{"id":9586,"date":"2022-11-15T00:00:00","date_gmt":"2022-11-14T16:00:00","guid":{"rendered":"https:\/\/www.franchise.com.hk\/%e9%9b%b2%e9%a0%82%e6%96%b0%e8%80%80%e5%ae%a3%e4%bd%88%e4%b8%ad%e5%9c%8b%e5%9c%8b%e5%ae%b6%e8%97%a5%e5%93%81%e7%9b%a3%e7%9d%a3%e7%ae%a1%e7%90%86%e5%b1%80%e5%8f%97%e7%90%86nefecon%e7%94%a8%e6%96%bc\/9586"},"modified":"2022-11-15T00:00:00","modified_gmt":"2022-11-14T16:00:00","slug":"%e9%9b%b2%e9%a0%82%e6%96%b0%e8%80%80%e5%ae%a3%e4%bd%88%e4%b8%ad%e5%9c%8b%e5%9c%8b%e5%ae%b6%e8%97%a5%e5%93%81%e7%9b%a3%e7%9d%a3%e7%ae%a1%e7%90%86%e5%b1%80%e5%8f%97%e7%90%86nefecon%e7%94%a8%e6%96%bc","status":"publish","type":"post","link":"https:\/\/www.franchise.com.hk\/zh-hans\/%e9%9b%b2%e9%a0%82%e6%96%b0%e8%80%80%e5%ae%a3%e4%bd%88%e4%b8%ad%e5%9c%8b%e5%9c%8b%e5%ae%b6%e8%97%a5%e5%93%81%e7%9b%a3%e7%9d%a3%e7%ae%a1%e7%90%86%e5%b1%80%e5%8f%97%e7%90%86nefecon%e7%94%a8%e6%96%bc\/9586","title":{"rendered":"\u96f2\u9802\u65b0\u8000\u5ba3\u4f48\u4e2d\u570b\u570b\u5bb6\u85e5\u54c1\u76e3\u7763\u7ba1\u7406\u5c40\u53d7\u7406Nefecon\u7528\u65bc\u6cbb\u7642\u539f\u767c\u6027IgA\u814e\u75c5\u7684\u65b0\u85e5\u4e0a\u5e02\u8a31\u53ef\u7533\u8acb"},"content":{"rendered":"

— Nefecon (\u5e03\u5730\u5948\u5fb7\u9072\u91cb\u81a0\u56ca)\u65b0\u85e5\u4e0a\u5e02\u8a31\u53ef\u7533\u8acb\u7684\u53d7\u7406\uff0c\u6a19\u8a8c\u8457\u96f2\u9802\u65b0\u8000\u5728\u70ba\u4e2d\u570b\u539f\u767c\u6027IgA\u814e\u75c5\u60a3\u8005\u63d0\u4f9b\u8a72\u75be\u75c5\u9996\u5275\u7642\u6cd5\u4e0a\uff0c\u53c8\u9081\u9032\u4e86\u91cd\u8981\u4e00\u6b65<\/p>\n

–\u4e2d\u570b\u73fe\u6709\u7d04500\u842cIgA\u814e\u75c5\u60a3\u8005\uff0c\u662f\u8a72\u75c5\u60a3\u8005\u4eba\u6578\u6700\u591a\u7684\u570b\u5bb6\uff0c\u4e14\u76ee\u524d\u570b\u5167\u5c1a\u7121\u91dd\u5c0d\u6027\u6cbb\u7642\u85e5\u7269<\/p>\n

–Nefecon \u5df2\u5728\u7f8e\u570b\u548c\u6b50\u76df\u7372\u6279\u4e0a\u5e02\uff0c\u5728\u4e2d\u570b\u88ab\u7d0d\u5165\u7a81\u7834\u6027\u6cbb\u7642\u54c1\u7a2e<\/p>\n

\u4e0a\u6d77<\/span>2022\u5e7411\u670815\u65e5<\/span> \/\u7f8e\u901a\u793e\/ —\u00a0\u96f2\u9802\u65b0\u8000<\/a>\uff08HKEX 1952.HK\uff09\u662f\u4e00\u5bb6\u5c08\u6ce8\u65bc\u5275\u65b0\u85e5\u958b\u767c\u53ca\u5546\u696d\u5316\u7684\u751f\u7269\u88fd\u85e5\u516c\u53f8\uff0c\u81f4\u529b\u65bc\u6eff\u8db3\u4e9e\u592a\u5e02\u5834\u5c1a\u672a\u88ab\u6eff\u8db3\u7684\u91ab\u7642\u9700\u6c42\uff0c\u4eca\u65e5\u5ba3\u4f48\u4e2d\u570b\u570b\u5bb6\u85e5\u54c1\u76e3\u7763\u7ba1\u7406\u5c40\uff08NMPA\uff09\u5df2\u53d7\u7406Nefecon\uff08\u7f8e\u570b\u5546\u54c1\u540d\uff1aTARPEYO\u00ae<\/span>\uff0c\u6b50\u76df\u5546\u54c1\u540d\uff1aKinpeygo\u00ae<\/span>\uff09\u7684\u65b0\u85e5\u4e0a\u5e02\u8a31\u53ef\u7533\u8acb\uff08NDA\uff09\uff0c\u7528\u65bc\u6cbb\u7642\u5177\u6709\u9032\u5c55\u98a8\u96aa\u7684\u539f\u767c\u6027IgA\u814e\u75c5\uff08IgAN\uff09\u6210\u4eba\u60a3\u8005\u3002Nefecon\u65b0\u85e5\u4e0a\u5e02\u8a31\u53ef\u7533\u8acb\u7684\u53d7\u7406\uff0c\u6a19\u8a8c\u8457\u5728\u70ba\u4e2d\u570b\u539f\u767c\u6027IgA\u814e\u75c5\u60a3\u8005\u63d0\u4f9b\u8a72\u75be\u75c5\u9996\u5275\u7642\u6cd5\u4e0a\uff0c\u96f2\u9802\u65b0\u8000\u53c8\u9081\u9032\u4e86\u91cd\u8981\u4e00\u6b65\u3002\u4e2d\u570b\u570b\u5bb6\u85e5\u54c1\u76e3\u7763\u7ba1\u7406\u5c40\u65bc2020\u5e7412\u6708\u5c07Nefecon\u7d0d\u5165\u7a81\u7834\u6027\u6cbb\u7642\uff08BTD\uff09\u54c1\u7a2e\u3002<\/p>\n

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\u96f2\u9802\u65b0\u8000\u65bc\u4eca\u5e744\u6708\u4efd\u516c\u4f48\u4e2d\u570b\u4eba\u7fa4\u4e9e\u7d44\u5728\u63a5\u53d7Nefecon\u6cbb\u76429\u500b\u6708\u5f8c\uff0c\u86cb\u767d\u5c3f\u4e0b\u964d\u548c\u7a69\u5b9a\u814e\u5c0f\u7403\u6ffe\u904e\u7387\uff08eGFR\uff09\u7684\u7d50\u679c\u8207\u95dc\u9375\u6027\u5168\u74033\u671f\u81e8\u5e8a\u7814\u7a76\u00a0NefIgArd A\u90e8\u5206\u7684\u4e3b\u8981\u7d50\u679c\u4e00\u81f4\u30022020\u5e7411\u6708\uff0cNefIgArd \u8a66\u9a57A\u90e8\u5206\u7684\u4e3b\u8981\u7d50\u679c\u986f\u793a\u9054\u5230\u4e86\u7814\u7a76\u9810\u8a2d\u7684\u4e3b\u8981\u7d42\u9ede\u30022022\u5e7410\u6708\uff0cA\u90e8\u5206\u7814\u7a76\u7d50\u679c\u5728\u300aKidney International\u300b\u96dc\u8a8c\u5168\u6587\u767c\u8868\u3002\u7d50\u679c\u986f\u793a\uff1a\u5728\u7dad\u6301\u7a69\u5b9aRAS\u963b\u65b7\u5291\u6cbb\u7642\u7684\u57fa\u790e\u4e0a\uff0c\u6cbb\u76429\u500b\u6708\u5f8c\uff0cNefecon\u7d44\u7684\u5c3f\u86cb\u767d\u808c\u9150\u6bd4\uff08UPCR\uff09\u8207\u5b89\u6170\u5291\u7d44\u76f8\u6bd4\u964d\u4f4e\u4e8627% (P = 0.0003) \uff0cNefecon\u7d44\u548c\u5b89\u6170\u5291\u7d44\u7684UPCR\u8f03\u57fa\u7dda\u503c\u5206\u5225\u6e1b\u5c1131%\u548c5%\u3002\u5728\u814e\u529f\u80fd\u4fdd\u8b77\u65b9\u9762\uff0c\u6cbb\u76429\u500b\u6708\u5f8c\uff0cNefecon\u7d44\u7684eGFR\u7dad\u6301\u7a69\u5b9a\uff0c\u8f03\u57fa\u7dda\u50c5\u4e0b\u964d0.17ml\/min\/1.73 m<\/span>2\uff0c\u800c\u5b89\u6170\u5291\u7d44\u7684eGFR\u4e0b\u964d4.04 ml\/min\/1.73 m<\/span>2\u3002Nefecon\u7d44\u7684eGFR\u6cbb\u7642\u7372\u76ca\u9054\u52303.87 ml\/min\/1.73 m<\/span>2\uff0c\u5177\u6709\u7d71\u8a08\u5b78\u610f\u7fa9(P = 0.0014)\u3002\u5728\u5b89\u5168\u6027\u65b9\u9762\uff0cNefecon\u8010\u53d7\u6027\u826f\u597d\uff0c\u672a\u767c\u751f\u56b4\u91cd\u7684\u611f\u67d3\u76f8\u95dc\u4e0d\u826f\u4e8b\u4ef6\u3002<\/p>\n

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\u95dc\u65bcNefecon<\/p>\n

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\u95dc\u65bcIgA\u814e\u75c5<\/p>\n

IgA \u814e\u75c5\u662f\u5c0e\u81f4\u6162\u6027\u814e\u81df\u75c5\uff08 CKD \uff09\u548c\u814e\u529f\u80fd\u8870\u7aed\u7684\u4e3b\u8981\u75c5\u56e0\uff0c\u662f\u4e00\u7a2e\u8207\u9032\u884c\u6027\u814e\u640d\u50b7\u76f8\u95dc\u7684\u6162\u6027\u3001\u9032\u884c\u6027\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u3002IgA \u814e\u75c5\u60a3\u8005\u7684\u4e3b\u8981\u7279\u9ede\u662f\u5b58\u5728\u5faa\u74b0\u548c\u814e\u5c0f\u7403\u514d\u75ab\u8907\u5408\u7269\u3002\u8a72\u514d\u75ab\u8907\u5408\u7269\u542b\u6709\u534a\u4e73\u7cd6\u7f3a\u9677\u578b IgA1 \uff08\u53ef\u88ab IgG \u81ea\u8eab\u6297\u9ad4\u76f4\u63a5\u4f5c\u7528\u65bc\u9278\u93c8\u5340\u57df\u7684 O- \u805a\u7cd6\uff09\u548c C3 \u3002IgA \u814e\u75c5\u9032\u5c55\u6703\u4f34\u767c\u814e\u5c0f\u7403\u786c\u5316\u3001\u814e\u9593\u8cea\u7e96\u7dad\u5316\u3001\u814e\u529f\u80fd\u4e0d\u5168\u3001\u86cb\u767d\u5c3f\u548c\u9ad8\u8840\u58d3\u3002\u5176\u4e2d 50% \u7684 IgA \u814e\u75c5\u60a3\u8005\u5728 30 \u5e74\u5167\u6703\u9032\u5c55\u70ba\u7d42\u672b\u671f\u814e\u75c5\uff08 ESRD\uff09\u3002ESRD \u7684\u6a19\u6e96\u6cbb\u7642\u662f\u900f\u6790\u6216\u814e\u79fb\u690d\uff0c\u9019\u7d66\u60a3\u8005\u9020\u6210\u4e86\u5de8\u5927\u7684\u5065\u5eb7\u7d93\u6fdf\u8ca0\u64d4\uff0c\u4e26\u986f\u8457\u5f71\u97ff\u751f\u6d3b\u8cea\u91cf\u3002\u76ee\u524d\u4e2d\u570b\u5c1a\u7121\u7372\u6279\u6cbb\u7642IgA\u814e\u75c5\u7684\u85e5\u7269\u3002<\/p>\n

\u95dc\u65bc\u96f2\u9802\u65b0\u8000<\/p>\n

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— Nefecon (\u5e03\u5730\u5948\u5fb7\u9072\u91cb\u81a0\u56ca)\u65b0\u85e5\u4e0a\u5e02\u8a31\u53ef\u7533\u8acb\u7684\u53d7\u7406\uff0c\u6a19\u8a8c\u8457\u96f2\u9802\u65b0\u8000\u5728\u70ba\u4e2d\u570b\u539f\u767c\u6027IgA\u814e\u75c5\u60a3\u8005\u63d0\u4f9b\u8a72\u75be\u75c5\u9996\u5275\u7642\u6cd5\u4e0a\uff0c\u53c8\u9081\u9032\u4e86\u91cd\u8981\u4e00\u6b65 –\u4e2d\u570b\u73fe\u6709\u7d04500\u842cIgA\u814e\u75c5\u60a3\u8005\uff0c\u662f\u8a72\u75c5\u60a3\u8005\u4eba\u6578\u6700\u591a\u7684\u570b\u5bb6\uff0c\u4e14\u76ee\u524d\u570b\u5167\u5c1a\u7121\u91dd\u5c0d\u6027\u6cbb\u7642\u85e5\u7269 –Nefecon \u5df2\u5728\u7f8e\u570b\u548c\u6b50\u76df\u7372\u6279\u4e0a\u5e02\uff0c\u5728\u4e2d\u570b\u88ab\u7d0d\u5165\u7a81\u7834\u6027\u6cbb\u7642\u54c1\u7a2e \u4e0a\u6d772022\u5e7411\u670815\u65e5 \/\u7f8e\u901a\u793e\/ —\u00a0\u96f2\u9802\u65b0\u8000\uff08HKEX 1952.HK\uff09\u662f\u4e00\u5bb6\u5c08\u6ce8\u65bc\u5275\u65b0\u85e5\u958b\u767c\u53ca\u5546\u696d\u5316\u7684\u751f\u7269\u88fd\u85e5\u516c\u53f8\uff0c\u81f4\u529b\u65bc\u6eff\u8db3\u4e9e\u592a\u5e02\u5834 … <\/p>\n

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