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2030 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\u81e8\u5e8a\u7814\u7a76\u6240\u53d6\u5f97\u7684\u6578\u64da\u7d50\u679c\u3002JX02002\u7814\u7a76\u9054\u5230\u4e86\u65b9\u6848\u9810\u8a2d\u7684\u4e3b\u8981\u7d42\u9ede\uff0c\u8207\u5b89\u6170\u5291\u76f8\u6bd4\uff0c\u4f7f\u7528\u827e\u66f2\u5e15\u7c73\u7684\u60a3\u8005\u5728\u7d66\u85e5\u5f8c\u768430\u5206\u9418\u5167\uff0cPSVT\u8f49\u5fa9\u70ba\u7ac7\u6027\u5fc3\u5f8b\u65b9\u9762\u5177\u6709\u986f\u8457\u512a\u6548\u6027\uff08\u98a8\u96aa\u6bd43.002\uff1bp=0.0005\uff09\u3002\u7e3d\u9ad4\u800c\u8a00\uff0c\u6cbb\u7642\u671f\u51fa\u73fe\u7684\u4e0d\u826f\u4e8b\u4ef6\uff08TEAEs\uff09\u5728\u827e\u66f2\u5e15\u7c73\u6cbb\u7642\u7d44\u548c\u5b89\u6170\u5291\u7d44\u4e4b\u9593\u76f8\u7576\u3002\u5c24\u70ba\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c\u5728\u6240\u67093\u671f\u8a66\u9a57\u4e2d\uff0c\u827e\u66f2\u5e15\u7c73\u7d66\u85e5\u5f8c 24 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= 2.62; p&lt;0.001\uff09\u3002\u827e\u66f2\u5e15\u7c73\u6cbb\u7642\u7d44\u7684\u4e2d\u4f4d\u8f49\u5fa9\u6642\u9593\u70ba17\u5206\u9418\uff0895% CI\uff1a13.4\uff0c26.5\uff09\uff0c\u800c\u5b89\u6170\u5291\u7d44\u70ba54\u5206\u9418\uff0895% CI\uff1a38.7\uff0c87.3\uff09\u3002\u00a0\u5728\u96a8\u6a5f\u81e8\u5e8a\u8a66\u9a57\u4e2d\uff0c\u767c\u751f\u7387\u22655%\u7684\u6700\u5e38\u898b\u4e0d\u826f\u4e8b\u4ef6\u6027\u8cea\u70ba\u8f15\u5ea6\u81f3\u4e2d\u5ea6\u4e14\u77ed\u66ab\uff0c\u5305\u62ec\u5c40\u90e8\u9f3b\u8154\u4e0d\u9069\u3001\u9f3b\u585e\u3001\u6d41\u6d95\u3001\u54bd\u5589\u523a\u6fc0\u548c\u9f3b\u51fa\u8840\u3002\u4e0d\u52302%\u7684\u8a66\u9a57\u53c3\u8207\u8005\u56e0\u4e0d\u826f\u4e8b\u4ef6\u800c\u505c\u6b62\u6cbb\u7642\u3002\u00a0<\/p>\n<p>\u827e\u66f2\u5e15\u7c73\u9f3b\u5674\u9727\u5291\u6b63\u958b\u767c\u7528\u65bcAFib-RVR\u9069\u61c9\u75c7<span>\u3002<\/span>\u5728\u570b\u969b\u591a\u4e2d\u5fc3\u3001\u96a8\u6a5f\u3001\u5b89\u6170\u5291\u5c0d\u7167\u7684II\u671f ReVeRA \u7814\u7a76\u4e2d\uff0c\u827e\u66f2\u5e15\u7c73\u986f\u8457\u4e14\u5feb\u901f\u5730\u964d\u4f4e\u4e86AFibRVR\u60a3\u8005\u7684\u5fc3\u5ba4\u7387\uff0c\u9054\u5230\u4e86\u4e3b\u8981\u7d42\u9ede\u3002\u63a5\u53d7\u827e\u66f2\u5e15\u7c73\u6cbb\u7642\u7684\u60a3\u8005\u4e2d\uff0c\u5fc3\u5ba4\u7387\u4f4e\u65bc100 bpm\u7684\u4eba\u6578\uff0858.3%\uff09\u9ad8\u65bc\u63a5\u53d7\u5b89\u6170\u5291\u6cbb\u7642\u7684\u4eba\u6578\uff084%\uff09\u3002\u5b89\u5168\u6027\u7e3d\u9ad4\u826f\u597d\u4e26\u8207\u65e2\u5f80\u7814\u7a76\u7d50\u679c\u4e00\u81f4\u3002<\/p>\n<p>\u95dc\u65bc\u827e\u66f2\u5e15\u7c73\u9f3b\u5674\u9727\u5291<\/p>\n<p>\u827e\u66f2\u5e15\u7c73\u662f\u4e00\u7a2e\u65b0\u7684\u5316\u5b78\u5be6\u9ad4\uff0c\u662fMilestone Pharmaceuticals, Inc.\uff08Nasdaq: MIST\uff09\u7684\u4e3b\u8981\u7814\u7a76\u7522\u54c1\u3002\u5b83\u662f\u4e00\u7a2e\u65b0\u578b\u7684\u9223\u901a\u9053\u963b\u6eef\u5291\uff0c\u65e8\u5728\u70ba\u767c\u4f5c\u6027\u5fc3\u8840\u7ba1\u75be\u75c5\u60a3\u8005\u63d0\u4f9b\u4e00\u7a2e\u5feb\u901f\u8d77\u6548\u7684\u7642\u6cd5\u3002\u4f5c\u70ba\u4e00\u7a2e\u7531\u60a3\u8005\u81ea\u884c\u7d66\u85e5\u7684\u9f3b\u5674\u9727\u5291\uff0c\u827e\u66f2\u5e15\u7c73\u9f3b\u5674\u9727\u5291\u5177\u6709\u6539\u8b8a\u7576\u524d\u60a3\u8005\u6cbb\u7642\u9ad4\u9a57\u7684\u6f5b\u529b\uff0c\u5f9e\u6025\u8a3a\u6cbb\u7642\u8f49\u70ba\u9662\u5916\u6cbb\u7642\u30022021\u5e745\u6708\uff0c\u7b95\u661f\u548cMilestone\u9054\u6210\u7368\u5bb6\u8a31\u53ef\u5354\u8b70\uff0c\u7372\u5f97\u5728\u5927\u4e2d\u83ef\u5340\u958b\u767c\u548c\u5546\u696d\u5316\u5728\u7814\u85e5\u7269\u827e\u66f2\u5e15\u7c73\u9f3b\u5674\u9727\u5291\uff08\u64ec\u5b9a\u4f7f\u7528\u7684\u4e2d\u6587\u5546\u54c1\u540d\uff1a\u661f\u5fc5\u59a5\u00ae\uff09\u6cbb\u7642PSVT\u548c\u5176\u5b83\u5fc3\u8840\u7ba1\u75be\u75c5\u7684\u7368\u5bb6\u8a31\u53ef\u6b0a\u3002<\/p>\n<p>\u95dc\u65bc\u96f2\u9802\u65b0\u8000<\/p>\n<p>\u96f2\u9802\u65b0\u8000\u662f\u4e00\u5bb6\u5c08\u6ce8\u65bc\u5275\u65b0\u85e5\u7814\u767c\u3001\u81e8\u5e8a\u958b\u767c\u3001\u88fd\u9020\u548c\u5546\u696d\u5316\u7684\u751f\u7269\u88fd\u85e5\u516c\u53f8\uff0c\u81f4\u529b\u65bc\u6eff\u8db3\u5168\u7403\u5e02\u5834\u5c1a\u672a\u6eff\u8db3\u7684\u91ab\u7642\u9700\u6c42\u3002\u96f2\u9802\u65b0\u8000\u7684\u7ba1\u7406\u5718\u968a\u5728\u4e2d\u570b\u53ca\u5168\u7403\u9818\u5148\u88fd\u85e5\u4f01\u696d\u64c1\u6709\u6df1\u539a\u7684\u5c08\u9577\u548c\u8c50\u5bcc\u7684\u7d93\u9a57\u3002\u516c\u53f8\u5728\u6d59\u6c5f\u5609\u5584\u64c1\u6709\u5177\u5099\u5546\u696d\u5316\u898f\u6a21\u7684\u5168\u7403\u751f\u7522\u57fa\u5730\uff0c\u4e26\u56b4\u683c\u6309\u7167\u570b\u5bb6\u85e5\u54c1\u76e3\u7763\u7ba1\u7406\u5c40\uff08NMPA\uff09\u548c\u6b50\u6d32\u85e5\u54c1\u7ba1\u7406\u5c40\uff08EMA\uff09\u7684GMP\u8981\u6c42\u53ca\u4e16\u754c\u885b\u751f\u7d44\u7e54\uff08WHO\uff09PQ\u6a19\u6e96\u5efa\u8a2d\u3002<\/p>\n<p>\u516c\u53f8\u805a\u7126\u81ea\u8eab\u514d\u75ab\u3001\u773c\u79d1\u3001\u6025\u91cd\u75c7\u53caCKM\uff08\u5fc3\u8840\u7ba1\u3001\u814e\u81df\u53ca\u4ee3\u8b1d\uff09\u7b49\u75be\u75c5\u6cbb\u7642\u9818\u57df\uff0c\u5df2\u6253\u9020\u96c6\u5168\u6e20\u9053\u5546\u696d\u5316\u9ad4\u7cfb\u8207\u85e5\u54c1\u5168\u751f\u547d\u9031\u671f\u5546\u696d\u5316\u80fd\u529b\u65bc\u4e00\u9ad4\u7684\u5546\u696d\u5316\u5e73\u53f0\uff0c\u4e26\u4ee5\u64c1\u6709\u5168\u7403\u6b0a\u76ca\u7684\u81ea\u7814mRNA\u5e73\u53f0\u70ba\u57fa\u790e\uff0c\u6301\u7e8c\u63a8\u9032mRNA in vivo CAR-T\u8207mRNA\u816b\u7624\u75ab\u82d7\u7b49\u73fe\u6709\u7ba1\u7dda\uff0c\u540c\u6642\u901a\u904e\u5f15\u9032\u53ca\u751f\u614b\u5b75\u5316\u6f5b\u529b\u5e73\u53f0\uff0c\u62d3\u5c55\u7814\u767c\u80fd\u529b\uff0c\u540c\u6642\u5f37\u5316\u5168\u7403\u5316\u4f48\u5c40\uff0c\u52a0\u5feb\u570b\u969b\u5316\u767c\u5c55\u9032\u7a0b\u3002\u66f4\u591a\u4fe1\u606f\uff0c\u8acb\u8a2a\u554f\u516c\u53f8\u5b98\u7db2\uff1a<a href=\"http:\/\/www.everestmedicines.com\/\" target=\"_blank\" rel=\"noopener\">www.everestmedicines.com<\/a>\u3002<\/p>\n<p>\u95dc\u65bc\u7b95\u661f\u85e5\u696d<\/p>\n<p>\u7b95\u661f\u85e5\u696d\u662f\u4e00\u5bb6\u81f4\u529b\u70ba\u5168\u7403\u5fc3\u8840\u7ba1\u4ee3\u8b1d\u75be\u75c5\u60a3\u8005\u958b\u767c\u5275\u65b0\u7642\u6cd5\u7684\u81e8\u5e8a\u968e\u6bb5\u7684\u751f\u7269\u88fd\u85e5\u516c\u53f8\u3002\u516c\u53f8\u5728\u7504\u5225\u3001\u5f15\u9032\u548c\u958b\u767c\u91dd\u5c0d\u5df2\u9a57\u8b49\u9776\u9ede\u53ca\u660e\u78ba\u4f5c\u7528\u6a5f\u5236\uff08MoA\uff09\u7684\u512a\u8cea\u81e8\u5e8a\u5019\u9078\u85e5\u7269\u65b9\u9762\u5177\u5099\u8c50\u5bcc\u7d93\u9a57\u548c\u5353\u8d8a\u5f80\u7e3e\u3002\u7b95\u661f\u85e5\u696d\u591a\u5143\u5316\u7684\u81e8\u5e8a\u968e\u6bb5\u7522\u54c1\u7ba1\u7dda\u6709\u671b\u91cd\u65b0\u5b9a\u7fa9\u6cbb\u7642\u6a19\u6e96\uff0c\u89e3\u6c7a\u7576\u4e0b\u591a\u7a2e\u5fc3\u8840\u7ba1\u4ee3\u8b1d\u75be\u75c5\u7642\u6cd5\u7684\u95dc\u9375\u5c40\u9650\u6027\u3002\u516c\u53f8\u6b63\u5728\u958b\u767c\u8986\u84cb\u5fc3\u8840\u7ba1\u4ee3\u8b1d\u75be\u75c5\u9818\u57df\u7684\u7cbe\u9078\u5c0f\u5206\u5b50\u5316\u5408\u7269\uff0c\u6838\u5fc3\u7522\u54c1\u5305\u62ec\u8655\u65bc\u81e8\u5e8a\u958b\u767c\u968e\u6bb5\u7684\u6cbb\u7642\u80a5\u80d6\u53ca\u8d85\u91cd\u30012\u578b\u7cd6\u5c3f\u75c5\u60a3\u8005\u7684\u53e3\u670d\u5c0f\u5206\u5b50GLP-1\u53d7\u9ad4\u6fc0\u52d5\u5291CX11\u3001\u6cbb\u7642\u6025\u6027\u7f3a\u8840\u6027\u8166\u5352\u4e2d\uff08AIS\uff09\u60a3\u8005\u7684\u5177\u6709\u6297\u708e\u7279\u6027\u7684\u65b0\u578b\u6eb6\u6813\u85e5\u7269JX10\u3001\u4ee5\u53ca\u8655\u65bc\u81e8\u5e8a\u524d\u958b\u767c\u968e\u6bb5\u7684\u53e3\u670d\u5c0f\u5206\u5b50\u80f0\u6fb1\u7d20\u53d7\u9ad4\u6fc0\u52d5\u5291CX12\u3002\u7b95\u661f\u85e5\u696d\u9084\u6709\u91dd\u5c0d\u5df2\u9a57\u8b49\u80a5\u80d6\u9776\u9ede\u7684\u5176\u4ed6\u5c0f\u5206\u5b50\u9805\u76ee\u8655\u65bc\u958b\u767c\u968e\u6bb5\u3002<\/p>\n<p>\u66f4\u591a\u4fe1\u606f\uff0c\u8acb\u8a2a\u554f<a href=\"http:\/\/www.corxelbio.com\/\" target=\"_blank\" rel=\"noopener\">www.corxelbio.com<\/a>\u548c\u300c\u7b95\u661f\u85e5\u696d\u300d\u5fae\u4fe1\u516c\u773e\u865f\u3002\u00a0<\/p>\n<p>\u524d\u77bb\u6027\u8072\u660e<br 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