{"id":23217,"date":"2024-11-17T14:42:00","date_gmt":"2024-11-17T06:42:00","guid":{"rendered":"https:\/\/www.franchise.com.hk\/%e9%a6%96%e5%80%8b%e5%9c%8b%e7%94%a2%e5%8e%9f%e7%a0%94bcl-2%e6%8a%91%e5%88%b6%e5%8a%91%ef%bc%81%e4%ba%9e%e7%9b%9b%e9%86%ab%e8%97%a5apg-2575%e6%96%b0%e8%97%a5%e4%b8%8a%e5%b8%82%e7%94%b3%e8%ab%8b\/23217"},"modified":"2024-11-17T14:42:00","modified_gmt":"2024-11-17T06:42:00","slug":"%e9%a6%96%e5%80%8b%e5%9c%8b%e7%94%a2%e5%8e%9f%e7%a0%94bcl-2%e6%8a%91%e5%88%b6%e5%8a%91%ef%bc%81%e4%ba%9e%e7%9b%9b%e9%86%ab%e8%97%a5apg-2575%e6%96%b0%e8%97%a5%e4%b8%8a%e5%b8%82%e7%94%b3%e8%ab%8b","status":"publish","type":"post","link":"https:\/\/www.franchise.com.hk\/zh-hans\/%e9%a6%96%e5%80%8b%e5%9c%8b%e7%94%a2%e5%8e%9f%e7%a0%94bcl-2%e6%8a%91%e5%88%b6%e5%8a%91%ef%bc%81%e4%ba%9e%e7%9b%9b%e9%86%ab%e8%97%a5apg-2575%e6%96%b0%e8%97%a5%e4%b8%8a%e5%b8%82%e7%94%b3%e8%ab%8b\/23217","title":{"rendered":"\u9996\u500b\u570b\u7522\u539f\u7814Bcl-2\u6291\u5236\u5291\uff01\u4e9e\u76db\u91ab\u85e5APG-2575\u65b0\u85e5\u4e0a\u5e02\u7533\u8acb\u7372\u53d7\u7406\u4e26\u88ab\u63a8\u85a6\u7d0d\u5165\u512a\u5148\u5be9\u8a55"},"content":{"rendered":"<p><span class=\"legendSpanClass\">\u99ac\u91cc\u862d\u5dde\u7f85\u514b\u7dad\u723e\u5e02\u548c\u4e2d\u570b\u8607\u5dde<\/span><span class=\"legendSpanClass\">2024\u5e7411\u670817\u65e5<\/span> \/\u7f8e\u901a\u793e\/ &#8212; \u81f4\u529b\u65bc\u5728\u816b\u7624\u7b49\u9818\u57df\u958b\u767c\u5275\u65b0\u85e5\u7269\u7684\u9818\u5148\u7684\u751f\u7269\u91ab\u85e5\u4f01\u696d\u2014\u2014\u4e9e\u76db\u91ab\u85e5\uff086855.HK\uff09\u4eca\u65e5\u5ba3\u5e03\uff0c\u516c\u53f8\u81ea\u4e3b\u7814\u767c\u7684\u65b0\u578b\u9078\u64c7\u6027Bcl-2\u6291\u5236\u5291APG-2575\uff08\u64ec\u5b9a\u4e2d\u6587\u901a\u7528\u540d\uff1a\u529b\u52dd\u514b\u62c9\u7247\uff09\u7684\u65b0\u85e5\u4e0a\u5e02\u7533\u8acb\uff08NDA\uff09\u5df2\u7372\u570b\u5bb6\u85e5\u54c1\u76e3\u7763\u7ba1\u7406\u5c40\uff08NMPA\uff09\u85e5\u54c1\u5be9\u8a55\u4e2d\u5fc3\uff08CDE\uff09\u53d7\u7406\uff0c\u4e26\u88ab\u63a8\u85a6\u7d0d\u5165\u512a\u5148\u5be9\u8a55\u7a0b\u5e8f\uff0c\u7528\u65bc\u6cbb\u7642\u96e3\u6cbb\u6216\u5fa9\u767c\u6027\uff08r\/r\uff09\u6162\u6027\u6dcb\u5df4\u7d30\u80de\u767d\u8840\u75c5\/\u5c0f\u6dcb\u5df4\u7d30\u80de\u6dcb\u5df4\u7624\uff08CLL\/SLL\uff09\u3002\u9019\u662f\u9996\u500b\u5728\u570b\u5167\u63d0\u4ea4NDA\u7684\u570b\u7522\u539f\u7814Bcl-2\u6291\u5236\u5291\uff0c\u6709\u671b\u6210\u70ba\u5168\u7403\u7b2c\u4e8c\u500b\u4e0a\u5e02\u7684Bcl-2\u6291\u5236\u5291\u3002<\/p>\n<div class=\"PRN_ImbeddedAssetReference\">\n<\/div>\n<p>\u6b64\u6b21\u63d0\u4ea4\u7684NDA\u662f\u57fa\u65bc\u4e00\u9805\u5728\u4e2d\u570b\u958b\u5c55\u7684\u95dc\u9375\u8a3b\u518aII\u671f\u81e8\u5e8a\u7814\u7a76\uff08APG2575CC201\uff09\u7d50\u679c\u3002\u8a72\u7814\u7a76\u65e8\u5728\u8a55\u4f30APG-2575\u55ae\u85e5\u6cbb\u7642r\/r CLL\/SLL\u60a3\u8005\u7684\u6709\u6548\u6027\u548c\u5b89\u5168\u6027\uff0c\u8a72\u7814\u7a76\u7684\u4e3b\u8981\u7d42\u9ede\u6307\u6a19\u70ba\u7e3d\u7de9\u89e3\u7387\uff08ORR\uff09\u3002<\/p>\n<p>CLL\/SLL\u662f\u4e00\u7a2e\u6210\u719fB\u6dcb\u5df4\u7d30\u80de\u514b\u9686\u589e\u6b96\u6027\u816b\u7624\uff0c\u591a\u767c\u65bc\u8001\u5e74\u60a3\u8005\uff0c\u662f\u897f\u65b9\u570b\u5bb6\u6700\u5e38\u898b\u7684\u6210\u4eba\u767d\u8840\u75c5\u985e\u578b\uff0c\u5168\u7403\u6bcf\u5e74\u65b0\u589e\u75c5\u4f8b\u8d85\u904e10\u842c\u4f8b1\u3002\u4e2d\u570bCLL\/SLL\u7684\u767c\u75c5\u7387\u76f8\u5c0d\u6b50\u7f8e\u570b\u5bb6\u8f03\u4f4e\uff0c\u4f46\u5448\u660e\u986f\u4e0a\u5347\u8da8\u52e2\uff0c\u4e14\u5177\u6709\u767c\u75c5\u5e74\u9f61\u4f4e\u3001\u4fb5\u8972\u5ea6\u9ad8\u7b49\u7279\u9ede2\u3002SLL\u8207CLL\u662f\u540c\u4e00\u7a2e\u75be\u75c5\u7684\u4e0d\u540c\u8868\u73fe\uff0c\u7d0420\uff05\u7684SLL\u9032\u5c55\u70baCLL3\u3002\u5118\u7ba1\u514d\u75ab\u5316\u7642\u53ca\u5e03\u9b6f\u9813\u916a\u6c28\u9178\u6fc0\u9176\u6291\u5236\u5291\uff08BTKi\uff09\u7b49\u6cbb\u7642\u624b\u6bb5\u660e\u986f\u63d0\u9ad8\u4e86CLL\/SLL\u60a3\u8005\u521d\u6cbb\u7de9\u89e3\u7387\uff0c\u4f46\u56e0\u73fe\u6709\u6cbb\u7642\u65b9\u6cd5\u7684\u5c40\u9650\u3001\u60a3\u8005\u9810\u5f8c\u4e0d\u4f73\u3001\u75be\u75c5\u5c0d\u751f\u6d3b\u8cea\u91cf\u7684\u56b4\u91cd\u5f71\u97ff\u548c\u816b\u7624\u672c\u8eab\u7684\u8907\u96dc\u6027\u7b49\u539f\u56e0\uff0cr\/r CLL\/SLL\u60a3\u8005\u4ecd\u8feb\u5207\u9700\u8981\u66f4\u5b89\u5168\u6709\u6548\u7684\u6cbb\u7642\u9078\u64c7\u3002<\/p>\n<p>Bcl-2\u6291\u5236\u5291\u7684\u51fa\u73fe\u8b93CLL\/SLL\u7684\u6cbb\u7642\u6709\u4e86\u9032\u4e00\u6b65\u7684\u9769\u65b0\u3002Bcl-2\u662f\u4e00\u7a2e\u51cb\u4ea1\u6291\u5236\u56e0\u5b50\uff0c\u53ef\u4ee5\u63a7\u5236\u7dda\u7c92\u9ad4\u819c\u901a\u900f\u6027\u4f86\u8abf\u7bc0\u7d30\u80de\u5b58\u6d3b\uff0c\u901a\u904e\u6291\u5236\u7dda\u7c92\u9ad4\u7d30\u80de\u8272\u7d20C\u7684\u91cb\u653e\uff0c\u6216\u8005\u7d50\u5408\u51cb\u4ea1\u6fc0\u6d3b\u56e0\u5b50\uff0c\u4f86\u6291\u5236\u51cb\u4ea1\u86cb\u767d\u9176\u7684\u6d3b\u6027\u3002Bcl-2\u5728\u8a31\u591a\u60e1\u6027\u8840\u6db2\u816b\u7624\u7279\u5225\u662fCLL\/SLL\u4e2d\u904e\u5ea6\u8868\u9054\uff0c\u662f\u816b\u7624\u7d30\u80de\u9003\u907f\u51cb\u4ea1\u7684\u91cd\u8981\u6a5f\u5236\u4e4b\u4e00\u3002<\/p>\n<p>\u7136\u800cBcl-2\u9776\u9ede\u6210\u85e5\u6027\u96e3\u5ea6\u5f88\u9ad8\uff0c\u4e3b\u8981\u662f\u56e0\u70ba\u5176\u4f5c\u7528\u6a5f\u5236\u662f\u86cb\u767d-\u86cb\u767d\u76f8\u4e92\u4f5c\u7528 (Protein-protein Interaction, PPI)\uff0c\u9776\u9ede\u7d50\u5408\u754c\u9762\u6bd4\u8f03\u5927\uff0c\u5f88\u96e3\u8a2d\u8a08\u5c0f\u5206\u5b50\u53bb\u6291\u5236\u4e26\u767c\u63ee\u963b\u65b7\u4f5c\u7528\u3002\u6b64\u5916\uff0cBcl-2\u9776\u9ede\u4f4d\u65bc\u7dda\u7c92\u9ad4\u819c\u4e0a\uff0c\u7dda\u7c92\u9ad4\u662f\u96d9\u819c\u7d50\u69cb\uff0c\u5c6c\u65bc\u7d30\u80de\u4e2d\u7d50\u69cb\u6700\u8907\u96dc\u3001\u6700\u96e3\u7684\u90e8\u5206\u4e4b\u4e00\uff0c\u85e5\u7269\u9700\u8981\u5148\u901a\u904e\u7d30\u80de\u819c\u9032\u5165\u7d30\u80de\u5f8c\u624d\u80fd\u9032\u4e00\u6b65\u4f5c\u7528\u65bc\u7dda\u7c92\u9ad4\u819c\u4e0a\uff0c\u9019\u7121\u7591\u66f4\u52a0\u5927\u6210\u85e5\u96e3\u5ea6\u3002\u9776\u9ede\u767c\u73fe\u81f3\u4eca\u8fd140\u5e74\uff0c\u5168\u7403\u53ea\u6709\u4e00\u6b3e\u9776\u5411Bcl-2\u7684\u6291\u5236\u5291\u7372\u6279\u4e0a\u5e02\uff0c\u5145\u5206\u5c55\u73fe\u4e86\u8a72\u9818\u57df\u7684\u7814\u767c\u96e3\u5ea6\u8207\u6311\u6230\u3002\u570b\u5916CLL\/SLL\u6cbb\u7642\u5df2\u9032\u5165\u4e86\u300c\u7121\u5316\u7642\u300d\u3001\u300c\u56fa\u5b9a\u7642\u7a0b\u300d\u7684\u65b0\u6642\u4ee3\uff0c\u800c\u6b64\u524d\u8a72\u6cbb\u7642\u9818\u57df\u5c1a\u672a\u6709\u4efb\u4f55\u4e00\u6b3eBcl-2\u6291\u5236\u5291\u5728\u4e2d\u570b\u7372\u6279\uff0c\u56e0\u6b64\u570b\u5167\u4e5f\u6025\u9700\u65b0\u7684\u6cbb\u7642\u9078\u64c7\u3002<\/p>\n<p>APG-2575\u662f\u4e9e\u76db\u91ab\u85e5\u81ea\u4e3b\u7814\u767c\u7684\u65b0\u578b\u53e3\u670dBcl-2\u9078\u64c7\u6027\u6291\u5236\u5291\uff0c\u901a\u904e\u9078\u64c7\u6027\u6291\u5236Bcl-2\u86cb\u767d\uff0c\u6062\u5fa9\u816b\u7624\u7d30\u80de\u7684\u6b63\u5e38\u51cb\u4ea1\u904e\u7a0b\uff0c\u5f9e\u800c\u9054\u5230\u6cbb\u7642\u816b\u7624\u7684\u76ee\u7684\u3002APG-2575\u662f\u5168\u7403\u7b2c\u4e8c\u500b\u3001\u4e2d\u570b\u9996\u500b\u770b\u5230\u660e\u78ba\u7642\u6548\u3001\u4e26\u9032\u5165\u95dc\u9375\u8a3b\u518a\u81e8\u5e8a\u968e\u6bb5\u7684Bcl-2\u6291\u5236\u5291\uff0c\u5728\u591a\u7a2e\u8840\u6db2\u816b\u7624\u548c\u5be6\u9ad4\u7624\u6cbb\u7642\u9818\u57df\u5177\u5099\u5ee3\u95ca\u7684\u6cbb\u7642\u524d\u666f\uff0c\u7279\u5225\u5728CLL\/SLL\u60a3\u8005\u4e2d\u5177\u6709\u55ae\u85e5\u548c\u806f\u5408\u6cbb\u7642\u6f5b\u529b\u3002APG-2575\u5728\u5168\u7403\u5c64\u9762\u5177\u540c\u985e\u6700\u4f73\uff08Best-in-class\uff09\u6f5b\u529b\uff0c\u6709\u671b\u6210\u70ba\u66f4\u5b89\u5168\u3001\u6709\u6548\uff0c\u4e14\u4fbf\u6377\u7684\u6cbb\u7642\u9078\u64c7\u3002<\/p>\n<p>\u540c\u6642\uff0cAPG-2575\u6b63\u5728\u958b\u5c55\u591a\u9805\u8a3b\u518aIII\u671f\u81e8\u5e8a\u8a66\u9a57\uff0c\u5206\u5225\u70ba\u806f\u5408BTKi\u6cbb\u7642\u7d93\u6cbbCLL\/SLL\u60a3\u8005\u7684\u5168\u7403\u8a3b\u518aIII\u671f\u81e8\u5e8a\u8a66\u9a57\uff08\u7531\u7f8e\u570bFDA\u8a31\u53ef\uff09\uff1b\u806f\u5408\u963f\u53ef\u66ff\u5c3c\u4e00\u7dda\u6cbb\u7642\u521d\u6cbbCLL\/SLL\u60a3\u8005\u7684\u5168\u7403\u8a3b\u518aIII\u671f\u81e8\u5e8a\u8a66\u9a57\uff1b\u806f\u5408\u963f\u624e\u80de\u7518\uff08AZA\uff09\u4e00\u7dda\u6cbb\u7642\u65b0\u8a3a\u65b7\u8001\u5e74\u6216\u4e0d\u8010\u53d7\u6a19\u6e96\u5316\u7642\u7684\u6025\u6027\u9ad3\u7cfb\u767d\u8840\u75c5\uff08AML\uff09\u60a3\u8005\u7684\u5168\u7403\u8a3b\u518aIII\u671f\u81e8\u5e8a\u8a66\u9a57\uff1b\u806f\u5408AZA\u4e00\u7dda\u6cbb\u7642\u65b0\u8a3a\u65b7\u4e2d\u9ad8\u5371\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u5f81\uff08MDS\uff09\u60a3\u8005\u7684\u5168\u7403\u8a3b\u518aIII\u671f\u81e8\u5e8a\u8a66\u9a57\u3002<\/p>\n<p>\u4e9e\u76db\u91ab\u85e5\u8463\u4e8b\u9577\u3001CEO\u694a\u5927\u4fca\u535a\u58eb\u8868\u793a\uff1a\u300c\u4e9e\u76db\u91ab\u85e5\u5275\u59cb\u5718\u968a\u5728\u7d30\u80de\u51cb\u4ea1\u9818\u57df\u5df2\u670920\u591a\u5e74\u7684\u7814\u767c\u6b77\u53f2\uff0c\u91dd\u5c0dBcl-2\u9776\u9ede\u66f4\u662f\u6df1\u5ea6\u5e03\u5c40\u3002\u76ee\u524d\u5168\u7403\u50c5\u6709\u4e00\u6b3eBcl-2\u6291\u5236\u5291\u7372\u6279\u4e0a\u5e02, \u5145\u5206\u8aaa\u660e\u4e86\u8a72\u9818\u57df\u85e5\u7269\u7814\u767c\u7684\u96e3\u5ea6\u548c\u6311\u6230\u3002\u6b64\u6b21\u6211\u5011\u63d0\u4ea4APG-2575\u7684NDA\uff0c\u610f\u5473\u8457\u8a72\u54c1\u7a2e\u5c07\u6210\u70ba\u9996\u500b\u570b\u7522\u539f\u7814Bcl-2\u6291\u5236\u5291\uff0c\u9019\u4e00\u9032\u5c55\u7121\u7591\u662f\u4e9e\u76db\u91ab\u85e5\u5341\u4e94\u5e74\u6df1\u8015\u6b77\u7a0b\u4e2d\u53c8\u4e00\u500b\u5177\u6709\u6a19\u8a8c\u6027\u610f\u7fa9\u7684\u91cc\u7a0b\u7891\u3002<\/p>\n<p>\u91dd\u5c0dr\/r CLL\/SLL\u60a3\u8005\u7684\u6cbb\u7642\u662f\u76ee\u524d\u5168\u7403\u5c1a\u672a\u6eff\u8db3\u7684\u81e8\u5e8a\u9700\u6c42\uff0cAPG-2575\u8d70\u5230\u9019\u4e00\u95dc\u9375\u7bc0\u9ede\uff0c\u9ad4\u73fe\u4e86\u4e9e\u76db\u91ab\u85e5\u5728\u5168\u7403\u91ab\u85e5\u9818\u57df\u7684\u5275\u65b0\u5be6\u529b\u3002\u6211\u5011\u5c07\u52a0\u901fAPG-2575\u5728\u5168\u7403\u5c64\u9762\u591a\u9069\u61c9\u75c7\u9818\u57df\u7684\u958b\u767c\uff0c\u66f4\u5feb\u5730\u9020\u798f\u60a3\u8005\u3002\u540c\u6642\u4e9e\u76db\u4e5f\u5c07\u7e7c\u7e8c\u5805\u5b88\u300e\u89e3\u6c7a\u4e2d\u570b\u4e43\u81f3\u5168\u7403\u60a3\u8005\u5c1a\u672a\u6eff\u8db3\u7684\u81e8\u5e8a\u9700\u6c42\u300f\u7684\u4f7f\u547d\uff0c\u5e36\u4f86\u66f4\u591a\u91cd\u78c5\u5275\u65b0\u85e5\u7269\uff0c\u60e0\u53ca\u66f4\u591a\u60a3\u8005\u3002\u300d<\/p>\n<p>\u53c3\u8003\u8cc7\u6599\uff1a<\/p>\n<p>1.\u00a0\u00a0\u00a0\u00a0 Yao, Y., Lin, X., Li, F., et al. The global burden and attributable risk factors of chronic lymphocytic leukemia in 204 countries and territories from 1990 to 2019: analysis based on the global burden of disease study 2019. Biomed Eng Online. 2022 Jan 11;21(1):4. DOI: 10.1186\/s12938-021-00973-6<\/p>\n<p>2.\u00a0\u00a0\u00a0\u00a0 \u5289\u6f8e. \u5fa9\u65e6\u5927\u5b78\u9644\u5c6c\u4e2d\u5c71\u91ab\u9662\u6162\u6027\u6dcb\u5df4\u7d30\u80de\u767d\u7d30\u80de\/\u5c0f\u6dcb\u5df4\u7d30\u80de\u6dcb\u5df4\u7624\u8a3a\u7642\u898f\u8303\uff08v1.2018\uff09[J].\u4e2d\u570b\u81e8\u5e8a\u91ab\u5b78, 2018, 25(1): 157-160. DOI: 10.12015\/j. issn. 1008-6358. 2018. 20180<\/p>\n<p>3.\u00a0\u00a0\u00a0\u00a0 \u674e\u5efa\u52c7, \u90b1\u9304\u8cb4. \u4e2d\u570b\u6297\u764c\u5354\u6703\u8840\u6db2\u816b\u7624\u5c08\u696d\u59d4\u54e1\u6703,\u4e2d\u83ef\u91ab\u5b78\u6703\u8840\u6db2\u5b78\u5206\u6703.\u4e2d\u570b\u6162\u6027\u6dcb\u5df4\u7d30\u80de\u767d\u8840\u75c5\/\u5c0f\u6dcb\u5df4\u7d30\u80de\u6dcb\u5df4\u7624\u7684\u8a3a\u65b7\u8207\u6cbb\u7642\u6307\u5357\uff082022\u5e74\u7248\uff09. \u4e2d\u83ef\u8840\u6db2\u5b78\u96dc\u8a8c, 2022,43(5) : 353-358. DOI: 10.3760\/cma.j.issn.0253-2727.2022.05.001<\/p>\n<p><span>\u95dc\u65bc\u4e9e\u76db\u91ab\u85e5<\/span><\/p>\n<p>\u4e9e\u76db\u91ab\u85e5\u662f\u4e00\u5bb6\u7d9c\u5408\u6027\u7684\u5168\u7403\u751f\u7269\u91ab\u85e5\u4f01\u696d\uff0c\u81f4\u529b\u65bc\u7814\u767c\u5275\u65b0\u85e5\uff0c\u4ee5\u89e3\u6c7a\u816b\u7624\u7b49\u9818\u57df\u5168\u7403\u60a3\u8005\u5c1a\u672a\u6eff\u8db3\u7684\u81e8\u5e8a\u9700\u6c42\u30022019\u5e7410\u670828\u65e5\uff0c\u516c\u53f8\u5728\u9999\u6e2f\u806f\u4ea4\u6240\u4e3b\u677f\u639b\u724c\u4e0a\u5e02\uff0c\u80a1\u7968\u4ee3\u78bc\uff1a6855.HK\u3002<\/p>\n<p>\u4e9e\u76db\u91ab\u85e5\u5df2\u5efa\u7acb\u8c50\u5bcc\u7684\u5275\u65b0\u85e5\u7522\u54c1\u7ba1\u7dda\uff0c\u5305\u62ec\u6291\u5236Bcl-2\u3001IAP \u6216 MDM2-p53 \u7b49\u7d30\u80de\u51cb\u4ea1\u901a\u8def\u95dc\u9375\u86cb\u767d\u7684\u6291\u5236\u5291\uff1b\u65b0\u4e00\u4ee3\u91dd\u5c0d\u764c\u75c7\u6cbb\u7642\u4e2d\u51fa\u73fe\u7684\u6fc0\u9176\u7a81\u8b8a\u9ad4\u7684\u6291\u5236\u5291\u7b49\uff0c\u70ba\u5168\u7403\u552f\u4e00\u5728\u7d30\u80de\u51cb\u4ea1\u901a\u8def\u95dc\u9375\u86cb\u767d\u9818\u57df\u5747\u6709\u81e8\u5e8a\u958b\u767c\u54c1\u7a2e\u7684\u5275\u65b0\u516c\u53f8\u3002\u76ee\u524d\u516c\u53f8\u5df2\u5728\u4e2d\u570b\u3001\u7f8e\u570b\u3001\u6fb3\u6d32\u53ca\u6b50\u6d32\u958b\u5c5540\u591a\u9805\u81e8\u5e8a\u8a66\u9a57\uff0c\u5176\u4e2d\u5305\u62ec13\u9805\u8a3b\u518a\u81e8\u5e8a\u7814\u7a76\uff08\u5df2\u5b8c\u6210\/\u9032\u884c\u4e2d\/\u64ec\u555f\u52d5\uff09\u3002<\/p>\n<p>\u7528\u65bc\u6cbb\u7642\u6162\u6027\u9ad3\u7d30\u80de\u767d\u8840\u75c5\u7684\u6838\u5fc3\u54c1\u7a2e\u8010\u7acb\u514b\u00ae\u66fe\u7372\u4e2d\u570b\u570b\u5bb6\u85e5\u54c1\u76e3\u7763\u7ba1\u7406\u5c40\u65b0\u85e5\u5be9\u8a55\u4e2d\u5fc3\uff08CDE\uff09\u7d0d\u5165\u512a\u5148\u5be9\u8a55\u548c\u7a81\u7834\u6027\u6cbb\u7642\u54c1\u7a2e\uff0c\u4e26\u5df2\u5728\u4e2d\u570b\u7372\u6279\uff0c\u662f\u516c\u53f8\u7684\u9996\u500b\u4e0a\u5e02\u54c1\u7a2e\u3002\u76ee\u524d\uff0c\u8010\u7acb\u514b\u00ae\u5df2\u88ab\u6210\u529f\u7d0d\u5165\u300a\u570b\u5bb6\u57fa\u672c\u91ab\u7642\u4fdd\u96aa\u3001\u5de5\u50b7\u4fdd\u96aa\u548c\u751f\u80b2\u4fdd\u96aa\u85e5\u54c1\u76ee\u9304\u300b\u3002\u8a72\u54c1\u7a2e\u9084\u7372\u5f97\u4e86\u7f8e\u570bFDA\u5feb\u901f\u901a\u9053\u8cc7\u683c\u3001\u5b64\u5152\u85e5\u8cc7\u683c\u8a8d\u5b9a\u4ee5\u53ca\u6b50\u76df\u5b64\u5152\u85e5\u8cc7\u683c\u8a8d\u5b9a\u3002<\/p>\n<p>\u622a\u81f3\u76ee\u524d\uff0c\u516c\u53f8\u5171\u67094\u500b\u5728\u7814\u65b0\u85e5\u7372\u5f9716\u9805FDA\u548c1\u9805\u6b50\u76df\u5b64\u5152\u85e5\u8cc7\u683c\u8a8d\u5b9a\uff0c2\u9805FDA\u5feb\u901f\u901a\u9053\u8cc7\u683c\u4ee5\u53ca2\u9805FDA\u5152\u7ae5\u7f55\u898b\u75c5\u8cc7\u683c\u8a8d\u8b49\u3002\u6191\u501f\u5f37\u5927\u7684\u7814\u767c\u80fd\u529b\uff0c\u4e9e\u76db\u91ab\u85e5\u5df2\u5728\u5168\u7403\u8303\u570d\u5167\u9032\u884c\u77e5\u8b58\u7522\u6b0a\u5e03\u5c40\uff0c\u4e26\u8207\u6b66\u7530\u3001\u9ed8\u6c99\u6771\u3001\u963f\u65af\u5229\u5eb7\u3001\u8f1d\u745e\u3001\u4fe1\u9054\u7b49\u9818\u5148\u7684\u751f\u7269\u5236\u85e5\u516c\u53f8\uff0c\u4ee5\u53caMD\u5b89\u5fb7\u68ee\u764c\u75c7\u4e2d\u5fc3\uff08MD Anderson Cancer Center\uff09\u3001\u6885\u5967\u91ab\u5b78\u4e2d\u5fc3\uff08Mayo Clinic\uff09\u3001\u4e39\u5a1c\u6cd5\u4f2f\u764c\u75c7\u7814\u7a76\u9662\uff08Dana-Farber Cancer Institute\uff09\u3001\u7f8e\u570b\u570b\u5bb6\u764c\u75c7\u7814\u7a76\u6240\uff08NCI\uff09\u548c\u5bc6\u897f\u6839\u5927\u5b78\u7b49\u5b78\u8853\u6a5f\u69cb\u9054\u6210\u5168\u7403\u5408\u4f5c\u95dc\u4fc2\u3002<\/p>\n<p>\u4e9e\u76db\u91ab\u85e5\u5df2\u69cb\u5efa\u5728\u539f\u5275\u65b0\u85e5\u7814\u767c\u8207\u81e8\u5e8a\u958b\u767c\u9818\u57df\u7d93\u9a57\u8c50\u5bcc\u7684\u570b\u969b\u5316\u4eba\u624d\u5718\u968a\uff0c\u4ee5\u53ca\u6210\u719f\u7684\u5546\u696d\u5316\u751f\u7522\u8207\u5e02\u5834\u71df\u92b7\u5718\u968a\u3002\u4e9e\u76db\u91ab\u85e5\u5c07\u4e0d\u65b7\u63d0\u9ad8\u7814\u767c\u80fd\u529b\uff0c\u52a0\u901f\u63a8\u9032\u516c\u53f8\u7522\u54c1\u7ba1\u7dda\u7684\u81e8\u5e8a\u958b\u767c\u9032\u5ea6\uff0c\u771f\u6b63\u8e10\u884c\u300c\u89e3\u6c7a\u4e2d\u570b\u4e43\u81f3\u5168\u7403\u60a3\u8005\u5c1a\u672a\u6eff\u8db3\u7684\u81e8\u5e8a\u9700\u6c42\u300d\u7684\u4f7f\u547d\uff0c\u4ee5\u9020\u798f\u66f4\u591a\u60a3\u8005\u3002<\/p>\n<p><span>\u524d\u77bb\u6027\u8072\u660e<\/span><\/p>\n<p>\u672c\u6587\u6240\u4f5c\u51fa\u7684\u524d\u77bb\u6027\u9673\u8ff0\u50c5\u8207\u672c\u6587\u4f5c\u51fa\u8a72\u9673\u8ff0\u7576\u65e5\u7684\u4e8b\u4ef6\u6216\u8cc7\u6599\u6709\u95dc\u3002\u9664\u6cd5\u5f8b\u898f\u5b9a\u5916\uff0c\u65bc\u4f5c\u51fa\u524d\u77bb\u6027\u9673\u8ff0\u7576\u65e5\u4e4b\u5f8c\uff0c\u7121\u8ad6\u662f\u5426\u51fa\u73fe\u65b0\u8cc7\u6599\u3001\u672a\u4f86\u4e8b\u4ef6\u6216\u5176\u4ed6\u60c5\u6cc1\uff0c\u6211\u5011\u4e26\u7121\u8cac\u4efb\u66f4\u65b0\u6216\u516c\u958b\u4fee\u6539\u4efb\u4f55\u524d\u77bb\u6027\u9673\u8ff0\u53ca\u9810\u6599\u4e4b\u5916\u7684\u4e8b\u4ef6\u3002\u8acb\u7d30\u95b1\u672c\u6587\uff0c\u4e26\u7406\u89e3\u6211\u5011\u7684\u5be6\u969b\u672a\u4f86\u696d\u7e3e\u6216\u8868\u73fe\u53ef\u80fd\u8207\u9810\u671f\u6709\u91cd\u5927\u5dee\u7570\u3002\u672c\u6587\u5167\u6240\u6709\u9673\u8ff0\u4e43\u672c\u6587\u7ae0\u520a\u767c\u65e5\u671f\u4f5c\u51fa\uff0c\u53ef\u80fd\u56e0\u672a\u4f86\u767c\u5c55\u800c\u51fa\u73fe\u8b8a\u52d5\u3002<\/p>","protected":false},"excerpt":{"rendered":"<p>\u99ac\u91cc\u862d\u5dde\u7f85\u514b\u7dad\u723e\u5e02\u548c\u4e2d\u570b\u8607\u5dde2024\u5e7411\u670817\u65e5 \/\u7f8e\u901a\u793e\/ &#8212; \u81f4\u529b\u65bc\u5728\u816b\u7624\u7b49\u9818\u57df\u958b\u767c\u5275\u65b0\u85e5\u7269\u7684\u9818\u5148\u7684\u751f\u7269\u91ab\u85e5\u4f01\u696d\u2014\u2014\u4e9e\u76db\u91ab\u85e5\uff086855.HK\uff09\u4eca\u65e5\u5ba3\u5e03\uff0c\u516c\u53f8\u81ea\u4e3b\u7814\u767c\u7684\u65b0\u578b\u9078\u64c7\u6027Bcl-2\u6291\u5236\u5291APG-2575\uff08\u64ec\u5b9a\u4e2d\u6587\u901a\u7528\u540d\uff1a\u529b\u52dd\u514b\u62c9\u7247\uff09\u7684\u65b0\u85e5\u4e0a\u5e02\u7533\u8acb\uff08NDA\uff09\u5df2\u7372\u570b\u5bb6\u85e5\u54c1\u76e3\u7763\u7ba1\u7406\u5c40\uff08NMPA\uff09\u85e5\u54c1\u5be9\u8a55\u4e2d\u5fc3\uff08CDE\uff09\u53d7\u7406\uff0c\u4e26\u88ab\u63a8\u85a6\u7d0d\u5165\u512a\u5148\u5be9\u8a55\u7a0b\u5e8f\uff0c\u7528\u65bc\u6cbb\u7642\u96e3\u6cbb\u6216\u5fa9\u767c\u6027\uff08r\/r\uff09\u6162\u6027\u6dcb\u5df4\u7d30\u80de\u767d\u8840\u75c5\/\u5c0f\u6dcb\u5df4\u7d30\u80de\u6dcb\u5df4\u7624\uff08CLL\/SLL\uff09\u3002\u9019\u662f\u9996\u500b\u5728\u570b\u5167\u63d0\u4ea4NDA\u7684\u570b\u7522\u539f\u7814Bcl-2\u6291 &#8230; <\/p>\n<p class=\"read-more-container\"><a title=\"\u9996\u500b\u570b\u7522\u539f\u7814Bcl-2\u6291\u5236\u5291\uff01\u4e9e\u76db\u91ab\u85e5APG-2575\u65b0\u85e5\u4e0a\u5e02\u7533\u8acb\u7372\u53d7\u7406\u4e26\u88ab\u63a8\u85a6\u7d0d\u5165\u512a\u5148\u5be9\u8a55\" class=\"read-more button\" href=\"https:\/\/www.franchise.com.hk\/zh-hans\/%e9%a6%96%e5%80%8b%e5%9c%8b%e7%94%a2%e5%8e%9f%e7%a0%94bcl-2%e6%8a%91%e5%88%b6%e5%8a%91%ef%bc%81%e4%ba%9e%e7%9b%9b%e9%86%ab%e8%97%a5apg-2575%e6%96%b0%e8%97%a5%e4%b8%8a%e5%b8%82%e7%94%b3%e8%ab%8b\/23217#more-23217\" aria-label=\"\u66f4\u591a \u9996\u500b\u570b\u7522\u539f\u7814Bcl-2\u6291\u5236\u5291\uff01\u4e9e\u76db\u91ab\u85e5APG-2575\u65b0\u85e5\u4e0a\u5e02\u7533\u8acb\u7372\u53d7\u7406\u4e26\u88ab\u63a8\u85a6\u7d0d\u5165\u512a\u5148\u5be9\u8a55\">\u4e86\u89e3\u8a73\u60c5<\/a><\/p>\n","protected":false},"author":0,"featured_media":23218,"comment_status":"","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_generate-full-width-content":"","spay_email":"","footnotes":""},"categories":[1],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v20.4 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>\u9996\u500b\u570b\u7522\u539f\u7814Bcl-2\u6291\u5236\u5291\uff01\u4e9e\u76db\u91ab\u85e5APG-2575\u65b0\u85e5\u4e0a\u5e02\u7533\u8acb\u7372\u53d7\u7406\u4e26\u88ab\u63a8\u85a6\u7d0d\u5165\u512a\u5148\u5be9\u8a55 - \u9999\u6e2f\u7279\u8a31\u7d93\u71df<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.franchise.com.hk\/zh-hans\/%e9%a6%96%e5%80%8b%e5%9c%8b%e7%94%a2%e5%8e%9f%e7%a0%94bcl-2%e6%8a%91%e5%88%b6%e5%8a%91%ef%bc%81%e4%ba%9e%e7%9b%9b%e9%86%ab%e8%97%a5apg-2575%e6%96%b0%e8%97%a5%e4%b8%8a%e5%b8%82%e7%94%b3%e8%ab%8b\/23217\" \/>\n<meta property=\"og:locale\" content=\"zh_CN\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u9996\u500b\u570b\u7522\u539f\u7814Bcl-2\u6291\u5236\u5291\uff01\u4e9e\u76db\u91ab\u85e5APG-2575\u65b0\u85e5\u4e0a\u5e02\u7533\u8acb\u7372\u53d7\u7406\u4e26\u88ab\u63a8\u85a6\u7d0d\u5165\u512a\u5148\u5be9\u8a55 - \u9999\u6e2f\u7279\u8a31\u7d93\u71df\" \/>\n<meta property=\"og:description\" content=\"\u99ac\u91cc\u862d\u5dde\u7f85\u514b\u7dad\u723e\u5e02\u548c\u4e2d\u570b\u8607\u5dde2024\u5e7411\u670817\u65e5 \/\u7f8e\u901a\u793e\/ &#8212; \u81f4\u529b\u65bc\u5728\u816b\u7624\u7b49\u9818\u57df\u958b\u767c\u5275\u65b0\u85e5\u7269\u7684\u9818\u5148\u7684\u751f\u7269\u91ab\u85e5\u4f01\u696d\u2014\u2014\u4e9e\u76db\u91ab\u85e5\uff086855.HK\uff09\u4eca\u65e5\u5ba3\u5e03\uff0c\u516c\u53f8\u81ea\u4e3b\u7814\u767c\u7684\u65b0\u578b\u9078\u64c7\u6027Bcl-2\u6291\u5236\u5291APG-2575\uff08\u64ec\u5b9a\u4e2d\u6587\u901a\u7528\u540d\uff1a\u529b\u52dd\u514b\u62c9\u7247\uff09\u7684\u65b0\u85e5\u4e0a\u5e02\u7533\u8acb\uff08NDA\uff09\u5df2\u7372\u570b\u5bb6\u85e5\u54c1\u76e3\u7763\u7ba1\u7406\u5c40\uff08NMPA\uff09\u85e5\u54c1\u5be9\u8a55\u4e2d\u5fc3\uff08CDE\uff09\u53d7\u7406\uff0c\u4e26\u88ab\u63a8\u85a6\u7d0d\u5165\u512a\u5148\u5be9\u8a55\u7a0b\u5e8f\uff0c\u7528\u65bc\u6cbb\u7642\u96e3\u6cbb\u6216\u5fa9\u767c\u6027\uff08r\/r\uff09\u6162\u6027\u6dcb\u5df4\u7d30\u80de\u767d\u8840\u75c5\/\u5c0f\u6dcb\u5df4\u7d30\u80de\u6dcb\u5df4\u7624\uff08CLL\/SLL\uff09\u3002\u9019\u662f\u9996\u500b\u5728\u570b\u5167\u63d0\u4ea4NDA\u7684\u570b\u7522\u539f\u7814Bcl-2\u6291 ... \u4e86\u89e3\u8a73\u60c5\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.franchise.com.hk\/zh-hans\/%e9%a6%96%e5%80%8b%e5%9c%8b%e7%94%a2%e5%8e%9f%e7%a0%94bcl-2%e6%8a%91%e5%88%b6%e5%8a%91%ef%bc%81%e4%ba%9e%e7%9b%9b%e9%86%ab%e8%97%a5apg-2575%e6%96%b0%e8%97%a5%e4%b8%8a%e5%b8%82%e7%94%b3%e8%ab%8b\/23217\" \/>\n<meta property=\"og:site_name\" content=\"\u9999\u6e2f\u7279\u8a31\u7d93\u71df\" \/>\n<meta property=\"article:published_time\" content=\"2024-11-17T06:42:00+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"\u9884\u8ba1\u9605\u8bfb\u65f6\u95f4\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 \u5206\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/www.franchise.com.hk\/zh-hans\/%e9%a6%96%e5%80%8b%e5%9c%8b%e7%94%a2%e5%8e%9f%e7%a0%94bcl-2%e6%8a%91%e5%88%b6%e5%8a%91%ef%bc%81%e4%ba%9e%e7%9b%9b%e9%86%ab%e8%97%a5apg-2575%e6%96%b0%e8%97%a5%e4%b8%8a%e5%b8%82%e7%94%b3%e8%ab%8b\/23217#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.franchise.com.hk\/zh-hans\/%e9%a6%96%e5%80%8b%e5%9c%8b%e7%94%a2%e5%8e%9f%e7%a0%94bcl-2%e6%8a%91%e5%88%b6%e5%8a%91%ef%bc%81%e4%ba%9e%e7%9b%9b%e9%86%ab%e8%97%a5apg-2575%e6%96%b0%e8%97%a5%e4%b8%8a%e5%b8%82%e7%94%b3%e8%ab%8b\/23217\"},\"author\":{\"name\":\"\",\"@id\":\"\"},\"headline\":\"\u9996\u500b\u570b\u7522\u539f\u7814Bcl-2\u6291\u5236\u5291\uff01\u4e9e\u76db\u91ab\u85e5APG-2575\u65b0\u85e5\u4e0a\u5e02\u7533\u8acb\u7372\u53d7\u7406\u4e26\u88ab\u63a8\u85a6\u7d0d\u5165\u512a\u5148\u5be9\u8a55\",\"datePublished\":\"2024-11-17T06:42:00+00:00\",\"dateModified\":\"2024-11-17T06:42:00+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.franchise.com.hk\/zh-hans\/%e9%a6%96%e5%80%8b%e5%9c%8b%e7%94%a2%e5%8e%9f%e7%a0%94bcl-2%e6%8a%91%e5%88%b6%e5%8a%91%ef%bc%81%e4%ba%9e%e7%9b%9b%e9%86%ab%e8%97%a5apg-2575%e6%96%b0%e8%97%a5%e4%b8%8a%e5%b8%82%e7%94%b3%e8%ab%8b\/23217\"},\"wordCount\":174,\"publisher\":{\"@id\":\"https:\/\/www.franchise.com.hk\/zh-hans#organization\"},\"articleSection\":[\"\u672a\u5206\u985e\"],\"inLanguage\":\"zh-Hans\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.franchise.com.hk\/zh-hans\/%e9%a6%96%e5%80%8b%e5%9c%8b%e7%94%a2%e5%8e%9f%e7%a0%94bcl-2%e6%8a%91%e5%88%b6%e5%8a%91%ef%bc%81%e4%ba%9e%e7%9b%9b%e9%86%ab%e8%97%a5apg-2575%e6%96%b0%e8%97%a5%e4%b8%8a%e5%b8%82%e7%94%b3%e8%ab%8b\/23217\",\"url\":\"https:\/\/www.franchise.com.hk\/zh-hans\/%e9%a6%96%e5%80%8b%e5%9c%8b%e7%94%a2%e5%8e%9f%e7%a0%94bcl-2%e6%8a%91%e5%88%b6%e5%8a%91%ef%bc%81%e4%ba%9e%e7%9b%9b%e9%86%ab%e8%97%a5apg-2575%e6%96%b0%e8%97%a5%e4%b8%8a%e5%b8%82%e7%94%b3%e8%ab%8b\/23217\",\"name\":\"\u9996\u500b\u570b\u7522\u539f\u7814Bcl-2\u6291\u5236\u5291\uff01\u4e9e\u76db\u91ab\u85e5APG-2575\u65b0\u85e5\u4e0a\u5e02\u7533\u8acb\u7372\u53d7\u7406\u4e26\u88ab\u63a8\u85a6\u7d0d\u5165\u512a\u5148\u5be9\u8a55 - \u9999\u6e2f\u7279\u8a31\u7d93\u71df\",\"isPartOf\":{\"@id\":\"https:\/\/www.franchise.com.hk\/zh-hans#website\"},\"datePublished\":\"2024-11-17T06:42:00+00:00\",\"dateModified\":\"2024-11-17T06:42:00+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/www.franchise.com.hk\/zh-hans\/%e9%a6%96%e5%80%8b%e5%9c%8b%e7%94%a2%e5%8e%9f%e7%a0%94bcl-2%e6%8a%91%e5%88%b6%e5%8a%91%ef%bc%81%e4%ba%9e%e7%9b%9b%e9%86%ab%e8%97%a5apg-2575%e6%96%b0%e8%97%a5%e4%b8%8a%e5%b8%82%e7%94%b3%e8%ab%8b\/23217#breadcrumb\"},\"inLanguage\":\"zh-Hans\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.franchise.com.hk\/zh-hans\/%e9%a6%96%e5%80%8b%e5%9c%8b%e7%94%a2%e5%8e%9f%e7%a0%94bcl-2%e6%8a%91%e5%88%b6%e5%8a%91%ef%bc%81%e4%ba%9e%e7%9b%9b%e9%86%ab%e8%97%a5apg-2575%e6%96%b0%e8%97%a5%e4%b8%8a%e5%b8%82%e7%94%b3%e8%ab%8b\/23217\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.franchise.com.hk\/zh-hans\/%e9%a6%96%e5%80%8b%e5%9c%8b%e7%94%a2%e5%8e%9f%e7%a0%94bcl-2%e6%8a%91%e5%88%b6%e5%8a%91%ef%bc%81%e4%ba%9e%e7%9b%9b%e9%86%ab%e8%97%a5apg-2575%e6%96%b0%e8%97%a5%e4%b8%8a%e5%b8%82%e7%94%b3%e8%ab%8b\/23217#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"\u9996\u9801\",\"item\":\"https:\/\/www.franchise.com.hk\/zh-hans\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"\u9996\u500b\u570b\u7522\u539f\u7814Bcl-2\u6291\u5236\u5291\uff01\u4e9e\u76db\u91ab\u85e5APG-2575\u65b0\u85e5\u4e0a\u5e02\u7533\u8acb\u7372\u53d7\u7406\u4e26\u88ab\u63a8\u85a6\u7d0d\u5165\u512a\u5148\u5be9\u8a55\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.franchise.com.hk\/zh-hans#website\",\"url\":\"https:\/\/www.franchise.com.hk\/zh-hans\",\"name\":\"\u9999\u6e2f\u7279\u8a31\u7d93\u71df\",\"description\":\"\u9999\u6e2f\u7279\u8a31\u7d93\u71df | Franchise HK\",\"publisher\":{\"@id\":\"https:\/\/www.franchise.com.hk\/zh-hans#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.franchise.com.hk\/zh-hans?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"zh-Hans\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.franchise.com.hk\/zh-hans#organization\",\"name\":\"\u9999\u6e2f\u7279\u8a31\u7d93\u71df\",\"url\":\"https:\/\/www.franchise.com.hk\/zh-hans\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"zh-Hans\",\"@id\":\"https:\/\/www.franchise.com.hk\/zh-hans#\/schema\/logo\/image\/\",\"url\":\"https:\/\/i0.wp.com\/www.franchise.com.hk\/wp-content\/uploads\/2022\/05\/cropped-cropped-franchise-logo-02-e1652686851566-2.png?fit=350%2C76&ssl=1\",\"contentUrl\":\"https:\/\/i0.wp.com\/www.franchise.com.hk\/wp-content\/uploads\/2022\/05\/cropped-cropped-franchise-logo-02-e1652686851566-2.png?fit=350%2C76&ssl=1\",\"width\":350,\"height\":76,\"caption\":\"\u9999\u6e2f\u7279\u8a31\u7d93\u71df\"},\"image\":{\"@id\":\"https:\/\/www.franchise.com.hk\/zh-hans#\/schema\/logo\/image\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"\u9996\u500b\u570b\u7522\u539f\u7814Bcl-2\u6291\u5236\u5291\uff01\u4e9e\u76db\u91ab\u85e5APG-2575\u65b0\u85e5\u4e0a\u5e02\u7533\u8acb\u7372\u53d7\u7406\u4e26\u88ab\u63a8\u85a6\u7d0d\u5165\u512a\u5148\u5be9\u8a55 - \u9999\u6e2f\u7279\u8a31\u7d93\u71df","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.franchise.com.hk\/zh-hans\/%e9%a6%96%e5%80%8b%e5%9c%8b%e7%94%a2%e5%8e%9f%e7%a0%94bcl-2%e6%8a%91%e5%88%b6%e5%8a%91%ef%bc%81%e4%ba%9e%e7%9b%9b%e9%86%ab%e8%97%a5apg-2575%e6%96%b0%e8%97%a5%e4%b8%8a%e5%b8%82%e7%94%b3%e8%ab%8b\/23217","og_locale":"zh_CN","og_type":"article","og_title":"\u9996\u500b\u570b\u7522\u539f\u7814Bcl-2\u6291\u5236\u5291\uff01\u4e9e\u76db\u91ab\u85e5APG-2575\u65b0\u85e5\u4e0a\u5e02\u7533\u8acb\u7372\u53d7\u7406\u4e26\u88ab\u63a8\u85a6\u7d0d\u5165\u512a\u5148\u5be9\u8a55 - \u9999\u6e2f\u7279\u8a31\u7d93\u71df","og_description":"\u99ac\u91cc\u862d\u5dde\u7f85\u514b\u7dad\u723e\u5e02\u548c\u4e2d\u570b\u8607\u5dde2024\u5e7411\u670817\u65e5 \/\u7f8e\u901a\u793e\/ &#8212; \u81f4\u529b\u65bc\u5728\u816b\u7624\u7b49\u9818\u57df\u958b\u767c\u5275\u65b0\u85e5\u7269\u7684\u9818\u5148\u7684\u751f\u7269\u91ab\u85e5\u4f01\u696d\u2014\u2014\u4e9e\u76db\u91ab\u85e5\uff086855.HK\uff09\u4eca\u65e5\u5ba3\u5e03\uff0c\u516c\u53f8\u81ea\u4e3b\u7814\u767c\u7684\u65b0\u578b\u9078\u64c7\u6027Bcl-2\u6291\u5236\u5291APG-2575\uff08\u64ec\u5b9a\u4e2d\u6587\u901a\u7528\u540d\uff1a\u529b\u52dd\u514b\u62c9\u7247\uff09\u7684\u65b0\u85e5\u4e0a\u5e02\u7533\u8acb\uff08NDA\uff09\u5df2\u7372\u570b\u5bb6\u85e5\u54c1\u76e3\u7763\u7ba1\u7406\u5c40\uff08NMPA\uff09\u85e5\u54c1\u5be9\u8a55\u4e2d\u5fc3\uff08CDE\uff09\u53d7\u7406\uff0c\u4e26\u88ab\u63a8\u85a6\u7d0d\u5165\u512a\u5148\u5be9\u8a55\u7a0b\u5e8f\uff0c\u7528\u65bc\u6cbb\u7642\u96e3\u6cbb\u6216\u5fa9\u767c\u6027\uff08r\/r\uff09\u6162\u6027\u6dcb\u5df4\u7d30\u80de\u767d\u8840\u75c5\/\u5c0f\u6dcb\u5df4\u7d30\u80de\u6dcb\u5df4\u7624\uff08CLL\/SLL\uff09\u3002\u9019\u662f\u9996\u500b\u5728\u570b\u5167\u63d0\u4ea4NDA\u7684\u570b\u7522\u539f\u7814Bcl-2\u6291 ... \u4e86\u89e3\u8a73\u60c5","og_url":"https:\/\/www.franchise.com.hk\/zh-hans\/%e9%a6%96%e5%80%8b%e5%9c%8b%e7%94%a2%e5%8e%9f%e7%a0%94bcl-2%e6%8a%91%e5%88%b6%e5%8a%91%ef%bc%81%e4%ba%9e%e7%9b%9b%e9%86%ab%e8%97%a5apg-2575%e6%96%b0%e8%97%a5%e4%b8%8a%e5%b8%82%e7%94%b3%e8%ab%8b\/23217","og_site_name":"\u9999\u6e2f\u7279\u8a31\u7d93\u71df","article_published_time":"2024-11-17T06:42:00+00:00","twitter_card":"summary_large_image","twitter_misc":{"\u9884\u8ba1\u9605\u8bfb\u65f6\u95f4":"1 \u5206"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.franchise.com.hk\/zh-hans\/%e9%a6%96%e5%80%8b%e5%9c%8b%e7%94%a2%e5%8e%9f%e7%a0%94bcl-2%e6%8a%91%e5%88%b6%e5%8a%91%ef%bc%81%e4%ba%9e%e7%9b%9b%e9%86%ab%e8%97%a5apg-2575%e6%96%b0%e8%97%a5%e4%b8%8a%e5%b8%82%e7%94%b3%e8%ab%8b\/23217#article","isPartOf":{"@id":"https:\/\/www.franchise.com.hk\/zh-hans\/%e9%a6%96%e5%80%8b%e5%9c%8b%e7%94%a2%e5%8e%9f%e7%a0%94bcl-2%e6%8a%91%e5%88%b6%e5%8a%91%ef%bc%81%e4%ba%9e%e7%9b%9b%e9%86%ab%e8%97%a5apg-2575%e6%96%b0%e8%97%a5%e4%b8%8a%e5%b8%82%e7%94%b3%e8%ab%8b\/23217"},"author":{"name":"","@id":""},"headline":"\u9996\u500b\u570b\u7522\u539f\u7814Bcl-2\u6291\u5236\u5291\uff01\u4e9e\u76db\u91ab\u85e5APG-2575\u65b0\u85e5\u4e0a\u5e02\u7533\u8acb\u7372\u53d7\u7406\u4e26\u88ab\u63a8\u85a6\u7d0d\u5165\u512a\u5148\u5be9\u8a55","datePublished":"2024-11-17T06:42:00+00:00","dateModified":"2024-11-17T06:42:00+00:00","mainEntityOfPage":{"@id":"https:\/\/www.franchise.com.hk\/zh-hans\/%e9%a6%96%e5%80%8b%e5%9c%8b%e7%94%a2%e5%8e%9f%e7%a0%94bcl-2%e6%8a%91%e5%88%b6%e5%8a%91%ef%bc%81%e4%ba%9e%e7%9b%9b%e9%86%ab%e8%97%a5apg-2575%e6%96%b0%e8%97%a5%e4%b8%8a%e5%b8%82%e7%94%b3%e8%ab%8b\/23217"},"wordCount":174,"publisher":{"@id":"https:\/\/www.franchise.com.hk\/zh-hans#organization"},"articleSection":["\u672a\u5206\u985e"],"inLanguage":"zh-Hans"},{"@type":"WebPage","@id":"https:\/\/www.franchise.com.hk\/zh-hans\/%e9%a6%96%e5%80%8b%e5%9c%8b%e7%94%a2%e5%8e%9f%e7%a0%94bcl-2%e6%8a%91%e5%88%b6%e5%8a%91%ef%bc%81%e4%ba%9e%e7%9b%9b%e9%86%ab%e8%97%a5apg-2575%e6%96%b0%e8%97%a5%e4%b8%8a%e5%b8%82%e7%94%b3%e8%ab%8b\/23217","url":"https:\/\/www.franchise.com.hk\/zh-hans\/%e9%a6%96%e5%80%8b%e5%9c%8b%e7%94%a2%e5%8e%9f%e7%a0%94bcl-2%e6%8a%91%e5%88%b6%e5%8a%91%ef%bc%81%e4%ba%9e%e7%9b%9b%e9%86%ab%e8%97%a5apg-2575%e6%96%b0%e8%97%a5%e4%b8%8a%e5%b8%82%e7%94%b3%e8%ab%8b\/23217","name":"\u9996\u500b\u570b\u7522\u539f\u7814Bcl-2\u6291\u5236\u5291\uff01\u4e9e\u76db\u91ab\u85e5APG-2575\u65b0\u85e5\u4e0a\u5e02\u7533\u8acb\u7372\u53d7\u7406\u4e26\u88ab\u63a8\u85a6\u7d0d\u5165\u512a\u5148\u5be9\u8a55 - \u9999\u6e2f\u7279\u8a31\u7d93\u71df","isPartOf":{"@id":"https:\/\/www.franchise.com.hk\/zh-hans#website"},"datePublished":"2024-11-17T06:42:00+00:00","dateModified":"2024-11-17T06:42:00+00:00","breadcrumb":{"@id":"https:\/\/www.franchise.com.hk\/zh-hans\/%e9%a6%96%e5%80%8b%e5%9c%8b%e7%94%a2%e5%8e%9f%e7%a0%94bcl-2%e6%8a%91%e5%88%b6%e5%8a%91%ef%bc%81%e4%ba%9e%e7%9b%9b%e9%86%ab%e8%97%a5apg-2575%e6%96%b0%e8%97%a5%e4%b8%8a%e5%b8%82%e7%94%b3%e8%ab%8b\/23217#breadcrumb"},"inLanguage":"zh-Hans","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.franchise.com.hk\/zh-hans\/%e9%a6%96%e5%80%8b%e5%9c%8b%e7%94%a2%e5%8e%9f%e7%a0%94bcl-2%e6%8a%91%e5%88%b6%e5%8a%91%ef%bc%81%e4%ba%9e%e7%9b%9b%e9%86%ab%e8%97%a5apg-2575%e6%96%b0%e8%97%a5%e4%b8%8a%e5%b8%82%e7%94%b3%e8%ab%8b\/23217"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/www.franchise.com.hk\/zh-hans\/%e9%a6%96%e5%80%8b%e5%9c%8b%e7%94%a2%e5%8e%9f%e7%a0%94bcl-2%e6%8a%91%e5%88%b6%e5%8a%91%ef%bc%81%e4%ba%9e%e7%9b%9b%e9%86%ab%e8%97%a5apg-2575%e6%96%b0%e8%97%a5%e4%b8%8a%e5%b8%82%e7%94%b3%e8%ab%8b\/23217#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"\u9996\u9801","item":"https:\/\/www.franchise.com.hk\/zh-hans"},{"@type":"ListItem","position":2,"name":"\u9996\u500b\u570b\u7522\u539f\u7814Bcl-2\u6291\u5236\u5291\uff01\u4e9e\u76db\u91ab\u85e5APG-2575\u65b0\u85e5\u4e0a\u5e02\u7533\u8acb\u7372\u53d7\u7406\u4e26\u88ab\u63a8\u85a6\u7d0d\u5165\u512a\u5148\u5be9\u8a55"}]},{"@type":"WebSite","@id":"https:\/\/www.franchise.com.hk\/zh-hans#website","url":"https:\/\/www.franchise.com.hk\/zh-hans","name":"\u9999\u6e2f\u7279\u8a31\u7d93\u71df","description":"\u9999\u6e2f\u7279\u8a31\u7d93\u71df | Franchise HK","publisher":{"@id":"https:\/\/www.franchise.com.hk\/zh-hans#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.franchise.com.hk\/zh-hans?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"zh-Hans"},{"@type":"Organization","@id":"https:\/\/www.franchise.com.hk\/zh-hans#organization","name":"\u9999\u6e2f\u7279\u8a31\u7d93\u71df","url":"https:\/\/www.franchise.com.hk\/zh-hans","logo":{"@type":"ImageObject","inLanguage":"zh-Hans","@id":"https:\/\/www.franchise.com.hk\/zh-hans#\/schema\/logo\/image\/","url":"https:\/\/i0.wp.com\/www.franchise.com.hk\/wp-content\/uploads\/2022\/05\/cropped-cropped-franchise-logo-02-e1652686851566-2.png?fit=350%2C76&ssl=1","contentUrl":"https:\/\/i0.wp.com\/www.franchise.com.hk\/wp-content\/uploads\/2022\/05\/cropped-cropped-franchise-logo-02-e1652686851566-2.png?fit=350%2C76&ssl=1","width":350,"height":76,"caption":"\u9999\u6e2f\u7279\u8a31\u7d93\u71df"},"image":{"@id":"https:\/\/www.franchise.com.hk\/zh-hans#\/schema\/logo\/image\/"}}]}},"jetpack_featured_media_url":"https:\/\/i0.wp.com\/www.franchise.com.hk\/wp-content\/uploads\/2024\/11\/Ascentage_Pharma_Logo-211DUQ.jpeg?fit=597%2C115&ssl=1","_links":{"self":[{"href":"https:\/\/www.franchise.com.hk\/zh-hans\/wp-json\/wp\/v2\/posts\/23217"}],"collection":[{"href":"https:\/\/www.franchise.com.hk\/zh-hans\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.franchise.com.hk\/zh-hans\/wp-json\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/www.franchise.com.hk\/zh-hans\/wp-json\/wp\/v2\/comments?post=23217"}],"version-history":[{"count":0,"href":"https:\/\/www.franchise.com.hk\/zh-hans\/wp-json\/wp\/v2\/posts\/23217\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.franchise.com.hk\/zh-hans\/wp-json\/wp\/v2\/media\/23218"}],"wp:attachment":[{"href":"https:\/\/www.franchise.com.hk\/zh-hans\/wp-json\/wp\/v2\/media?parent=23217"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.franchise.com.hk\/zh-hans\/wp-json\/wp\/v2\/categories?post=23217"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.franchise.com.hk\/zh-hans\/wp-json\/wp\/v2\/tags?post=23217"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}