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\u91dd\u5c0d\u4e9f\u5f85\u6eff\u8db3\u7684\u81e8\u5e8a\u9700\u6c42\uff0c\u5169\u9805\u6700\u65b0\u7a81\u7834\u6458\u8981\u51f8\u986f\u66ff\u96f7\u5229\u73e0\u55ae\u6297\u806f\u5408\u5316\u7642\u6cbb\u7642\u5be6\u9ad4\u816b\u7624\u7684\u7b56\u7565<\/p>\n

\u66f4\u591a\u6578\u64da\u5f70\u986f\u79d1\u5b78\u9a45\u52d5\u7684\u66ff\u96f7\u5229\u73e0\u55ae\u6297\u8207\u767e\u6fdf\u795e\u5dde\u7ba1\u7dda\u5206\u5b50\u806f\u5408\u7528\u85e5\u7684\u6f5b\u529b<\/p>\n

\u4e2d\u570b\u5317\u4eac\uff0c\u7f8e\u570b\u9ebb\u7701\u528d\u6a4b\u548c\u745e\u58eb\u5df4\u585e\u723e<\/span>2023\u5e7410\u670816\u65e5<\/span> \/\u7f8e\u901a\u793e\/ — \u767e\u6fdf\u795e\u5dde\uff08\u7d0d\u65af\u9054\u514b\u4ee3\u78bc\uff1aBGNE\uff1b\u9999\u6e2f\u806f\u4ea4\u6240\u4ee3\u78bc\uff1a06160\uff1b\u4e0a\u4ea4\u6240\u4ee3\u78bc\uff1a688235\uff09\u662f\u4e00\u5bb6\u5168\u7403\u6027\u751f\u7269\u79d1\u6280\u516c\u53f8\u3002\u516c\u53f8\u4eca\u65e5\u5ba3\u4f48\u5c07\u65bc2023\u5e74\u6b50\u6d32\u816b\u7624\u5167\u79d1\u5b78\u6703\uff08 ESMO\uff09\u5927\u6703\u4e0a\u5c55\u793a\u5176\u5145\u6eff\u524d\u666f\u7684\u65b0\u6578\u64da\uff0c\u5f70\u986f\u516c\u53f8\u5728\u5be6\u9ad4\u816b\u7624\u9818\u57df\u7a69\u5065\u7684\u3001\u4ee5\u79d1\u5b78\u70ba\u9a45\u52d5\u7684\u5546\u696d\u5316\u548c\u7ba1\u7dda\u85e5\u7269\u7522\u54c1\u7d44\u5408\u3002<\/p>\n

\u53c3\u6703\u4eae\u9ede\u5305\u62ec\u66ff\u96f7\u5229\u73e0\u55ae\u6297\uff08\u4e2d\u6587\u5546\u54c1\u540d\uff1a\u767e\u6fa4\u5b89\u00ae\uff0c\u82f1\u6587\u5546\u54c1\u540d\uff1aTEVIMBRA\u00ae\uff09\u7684\u5169\u9805\u6700\u65b0\u7a81\u7834\u6458\u8981\uff1a<\/p>\n

\u8a55\u4f30\u66ff\u96f7\u5229\u73e0\u55ae\u6297\u806f\u5408\u5316\u7642\u7528\u65bc\u665a\u671f\u80c3\u6216\u80c3\u98df\u7ba1\u7d50\u5408\u90e8\u817a\u764c\uff08GC\/GEJC\uff09\u4e00\u7dda\u6cbb\u7642\u7684\u5168\u74033\u671f\u7814\u7a76RATIONALE-305\uff08NCT03777657\uff09\u7684\u6700\u7d42\u5206\u6790\uff1b 3\u671f\u7814\u7a76RATIONALE-315\uff08NCT04379635\uff09\u7d50\u679c\u4e2d\uff0c\u66ff\u96f7\u5229\u73e0\u55ae\u6297\u806f\u5408\u5316\u7642\u4f5c\u70ba\u53ef\u5207\u9664\u7684II-IIIA\u671f\u975e\u5c0f\u7d30\u80de\u80ba\u764c\uff08NSCLC\uff09\u60a3\u8005\u65b0\u8f14\u52a9\u6cbb\u7642\u75c5\u7406\u5b78\u7de9\u89e3\u7684\u6700\u7d42\u5206\u6790 <\/p>\n

\u767e\u6fdf\u795e\u5dde\u5be6\u9ad4\u816b\u7624\u9996\u5e2d\u91ab\u5b78\u5b98Mark Lanasa\u91ab\u5b78\u535a\u58eb\u8868\u793a\uff1a\u300c\u57282023\u5e74ESMO\u5927\u6703\u4e0a\uff0c\u6211\u5011\u671f\u5f85\u5c55\u793a\u66ff\u96f7\u5229\u73e0\u55ae\u6297\u806f\u5408\u5176\u4ed6\u6cbb\u7642\u65b9\u6848\uff0c\u5728\u591a\u9805\u81e8\u5e8a\u8a66\u9a57\u4e2d\u7528\u65bc\u591a\u500b\u75be\u75c5\u9818\u57df\u548c\u591a\u7dda\u6cbb\u7642\u6642\u6240\u53d6\u5f97\u7684\u7d50\u679c\u3002\u66ff\u96f7\u5229\u73e0\u55ae\u6297\u662f\u767e\u6fdf\u795e\u5dde\u591a\u6a23\u5316\u7ba1\u7dda\u7684\u57fa\u77f3\u7522\u54c1\uff0c\u6211\u5011\u7684\u6cdb\u5be6\u9ad4\u816b\u7624\u9805\u76ee\u8457\u773c\u65bc\u65b0\u4e00\u6ce2\u514d\u75ab\u816b\u7624\u9776\u9ede\u3002\u6211\u5011\u5f88\u9ad8\u8208\u4e8e\u8fd1\u671f\u91cd\u65b0\u7372\u5f97\u9019\u4e00\u91cd\u8981\u85e5\u7269\u7684\u5168\u7403\u6b0a\u5229\uff0c\u4e26\u5c07\u7e7c\u7e8c\u9075\u5faa\u79d1\u5b78\u548c\u6578\u64da\uff0c\u63a8\u9032\u65b0\u7684\u6cbb\u7642\u5be6\u9ad4\u816b\u7624\u7684\u806f\u5408\u7528\u85e5\u7b56\u7565\u3002\u300d<\/p>\n

\u66ff\u96f7\u5229\u73e0\u55ae\u6297\u8fd1\u671f\u7372\u5f97\u6b50\u76df\u59d4\u54e1\u6703\uff08EC\uff09\u6279\u51c6\uff0c\u4f5c\u70ba\u55ae\u85e5\u7528\u65bc\u6cbb\u7642\u65e2\u5f80\u63a5\u53d7\u904e\u542b\u9251\u5316\u7642\u7684\u4e0d\u53ef\u5207\u9664\u3001\u5c40\u90e8\u665a\u671f\u6216\u8f49\u79fb\u6027\u98df\u7ba1\u9c57\u72c0\u7d30\u80de\u764c\uff08ESCC\uff09\u6210\u5e74\u60a3\u8005\u3002\u00a0\u6b64\u5916\uff0c\u7f8e\u570b\u98df\u54c1\u85e5\u54c1\u76e3\u7763\u7ba1\u7406\u5c40\uff08FDA\uff09\u6700\u8fd1\u4e5f\u5df2\u53d7\u7406\u66ff\u96f7\u5229\u73e0\u55ae\u6297\u7684\u4e00\u9805\u4e0a\u5e02\u8a31\u53ef\u7533\u8acb\uff0c\u7528\u65bc\u4e00\u7dda\u6cbb\u7642\u4e0d\u53ef\u5207\u9664\u7684\u5c40\u90e8\u665a\u671f\u3001\u5fa9\u767c\u6216\u8f49\u79fb\u6027ESCC\u60a3\u8005\u3002<\/p>\n

\u66f4\u591a\u767e\u6fdf\u795e\u5dde\u6458\u8981\u8a73\u60c5\u8acb\u898bESMO Programme<\/a>\u3002<\/p>\n

\u516c\u53f8\u7533\u8fa6\u7684\u81e8\u5e8a\u8a66\u9a57\u6578\u64da\u5c55\u793a\u5305\u62ec\uff1a<\/p>\n

\u66ff\u96f7\u5229\u73e0\u55ae\u6297<\/p>\n

RATIONALE-305\u8a66\u9a57\u7684\u6700\u7d42\u5206\u6790\u7d50\u679c\uff1a\u66ff\u96f7\u5229\u73e0\u55ae\u6297\u806f\u5408\u5316\u7642\u5c0d\u6bd4\u5b89\u6170\u5291\u806f\u5408\u5316\u7642\u7528\u65bc\u4e00\u7dda\u6cbb\u7642\u665a\u671f\u80c3\u6216\u80c3\u98df\u7ba1\u7d50\u5408\u90e8\u817a\u764c\uff08\u6458\u8981#LBA80\uff09
\n\u5c0f\u578b\u53e3\u982d\u5831\u544a\uff0c10 \u6708 21 \u65e5\u9031\u516d\u4e0b\u53485:25-5:30\uff08\u6b50\u6d32\u4e2d\u90e8\u590f\u4ee4\u6642\u9593\uff09
\n RATIONALE-315\u8a66\u9a57\uff1a\u8a55\u4f30\u6b643\u671f\u8a66\u9a57\u4e2d\uff0c\u53ef\u5207\u9664\u7684II-IIIA \u671f NSCLC \u60a3\u8005\u5c0d\u65b0\u8f14\u52a9\u66ff\u96f7\u5229\u73e0\u55ae\u6297\u806f\u5408\u542b\u9251\u96d9\u85e5\u5316\u7642\u7684\u75c5\u7406\u5b78\u7de9\u89e3\uff08\u6458\u8981#LBA58\uff09
\n\u5c0f\u578b\u53e3\u982d\u5831\u544a\uff0c10 \u6708 23 \u65e5\u9031\u4e00\u4e0b\u53482:55-3:00\uff08\u6b50\u6d32\u4e2d\u90e8\u590f\u4ee4\u6642\u9593\uff09
\n RATIONALE-306\u8a66\u9a57\u6578\u64da\u66f4\u65b0\uff1a\u66ff\u96f7\u5229\u73e0\u55ae\u6297\u806f\u5408\u5316\u7642\u5c0d\u6bd4\u5b89\u6170\u5291\u806f\u5408\u5316\u7642\u7528\u65bc\u4e00\u7dda\u6cbb\u7642\u665a\u671f\/\u8f49\u79fb\u6027ESCC\u7684\u96a8\u6a5f\u3001\u5168\u7403 3 \u671f\u7814\u7a76\uff08\u6458\u8981#1514P\uff09
\n\u6d77\u5831\u5c55\u793a\uff0c10 \u6708 23 \u65e5\u9031\u4e00
\n BGB-A317-209\u8a66\u9a57\uff1a\u66ff\u96f7\u5229\u73e0\u55ae\u6297\u55ae\u85e5\u6cbb\u7642\u65e2\u5f80\u7d93\u6cbb\u3001\u5c40\u90e8\u665a\u671f\u3001\u4e0d\u53ef\u5207\u9664\u6216\u8f49\u79fb\u6027\u9ad8\u5fae\u885b\u661f\u4e0d\u7a69\u5b9a\u6027\u6216\u932f\u914d\u4fee\u5fa9\u7f3a\u9677\u5be6\u9ad4\u7624\u60a3\u8005\u76842 \u671f\u7814\u7a76\u9577\u671f\u96a8\u8a2a\uff08\u6458\u8981#1057P\uff09
\n\u6d77\u5831\u5c55\u793a\uff0c10 \u6708 23 \u65e5\u9031\u4e00 <\/p>\n

\u6b50\u53f8\u73c0\u5229\u55ae\u6297\u958b\u767c\u9805\u76ee<\/p>\n

AdvanTIG-203\uff1a\u6b50\u53f8\u73c0\u5229\u55ae\u6297\u806f\u5408\u66ff\u96f7\u5229\u73e0\u55ae\u6297\u6cbb\u7642\u4e0d\u53ef\u5207\u9664\u3001\u5c40\u90e8\u665a\u671f\u3001\u5fa9\u767c\/\u8f49\u79fb\u6027ESCC\u548c\u7a0b\u5f0f\u6027\u7d30\u80de\u6b7b\u4ea1\u914d\u9ad41\uff08PDL1\uff09\u967d\u6027\u60a3\u8005\u76842\u671f\u3001\u96a8\u6a5f\u3001\u591a\u4e2d\u5fc3\u7814\u7a76\uff08\u6458\u8981#1020MO\uff09
\n\u5c0f\u578b\u53e3\u982d\u5831\u544a\uff0c10\u670821\u65e5\u9031\u516d\u4e0b\u53484:30-4:35\uff08\u6b50\u6d32\u4e2d\u90e8\u590f\u4ee4\u6642\u9593\uff09
\n AdvanTIG-206\uff1a\u6b50\u53f8\u73c0\u5229\u55ae\u6297\u806f\u5408\u66ff\u96f7\u5229\u73e0\u55ae\u6297\u8207BAT1706\uff08\u8c9d\u4f10\u73e0\u55ae\u6297\u751f\u7269\u985e\u4f3c\u85e5\uff09\u5c0d\u6bd4\u66ff\u96f7\u5229\u73e0\u55ae\u6297\u806f\u5408BAT1706\u7528\u65bc\u6cbb\u7642\u665a\u671f\u809d\u7d30\u80de\u764c\uff08HCC\uff09\u60a3\u8005\u76842\u671f\u3001\u96a8\u6a5f\u3001\u958b\u653e\u6027\u7814\u7a76\uff08\u6458\u8981#945MO\uff09
\n\u5c0f\u578b\u53e3\u982d\u5831\u544a\uff0c10\u670821\u65e5\u9031\u516d\u4e0b\u53484:30-4:35\uff08\u6b50\u6d32\u4e2d\u90e8\u590f\u4ee4\u6642\u9593\uff09
\n AdvanTIG-202\uff1a\u66ff\u96f7\u5229\u73e0\u55ae\u6297\u806f\u5408\u6216\u4e0d\u806f\u5408\u6b50\u53f8\u73c0\u5229\u55ae\u6297\u6cbb\u7642\u65e2\u5f80\u7d93\u6cbb\u5fa9\u767c\/\u8f49\u79fb\u6027\u5bae\u9838\u764c\u60a3\u8005\u76842\u671f\u3001\u96a8\u6a5f\u3001\u591a\u4e2d\u5fc3\u3001\u958b\u653e\u6027\u7814\u7a76\uff08\u6458\u8981#744MO\uff09
\n\u5c0f\u578b\u53e3\u982d\u5831\u544a\uff0c10\u670822\u65e5\u5468\u65e5\u4e0a\u534810:55-11:00\uff08\u6b50\u6d32\u4e2d\u90e8\u590f\u4ee4\u6642\u9593\uff09
\n AdvanTIG-105\uff1a\u6b50\u53f8\u73c0\u5229\u55ae\u6297\u806f\u5408\u66ff\u96f7\u5229\u73e0\u55ae\u6297\u8207\u5316\u7642\u7528\u65bc\u6cbb\u7642\u8f49\u79fb\u6027\u98df\u7ba1\u9c57\u72c0\u7d30\u80de\u764c\u548c\u98df\u7ba1\u817a\u764c\u60a3\u8005\u76841b\u671f\u5291\u91cf\u64f4\u5c55\u7814\u7a76\uff08\u6458\u8981#1533P\uff09
\n\u6d77\u5831\u5c55\u793a\uff0c10\u670823\u65e5\u9031\u4e00 <\/p>\n

\u5176\u4ed6\u7ba1\u7dda\u8cc7\u7522<\/p>\n

\u6fa4\u5c3c\u9054\u59a5\u55ae\u6297\u806f\u5408\u5316\u7642\u548c\u66ff\u96f7\u5229\u73e0\u55ae\u6297\u7528\u65bc\u4e00\u7dda\u6cbb\u7642\u665a\u671fHER2\u967d\u6027\u80c3\/\u80c3\u98df\u7ba1\u7d50\u5408\u90e8\u817a\u764c\u60a3\u8005\uff1a1b\/2\u671f\u7814\u7a76\u7684\u66f4\u65b0\u7d50\u679c\uff08\u6458\u8981#1518P\uff09
\n\u6d77\u5831\u5c55\u793a\uff0c10\u670823\u65e5\u9031\u4e00
\n \u53f8\u66f2\u66ff\u5c3c\u55ae\u85e5\u6216\u806f\u5408\u66ff\u96f7\u5229\u73e0\u55ae\u6297\u6cbb\u7642\u665a\u671f\u809d\u7d30\u80de\u764c\u548c\u80c3\/\u80c3\u98df\u7ba1\u7d50\u5408\u90e8\u817a\u764c\u76841\/2\u671f\u7814\u7a76\uff08\u6458\u8981#948P\uff09
\n\u6d77\u5831\u5c55\u793a\uff0c10\u670823\u65e5\u9031\u4e00 <\/p>\n

\u95dc\u65bc\u66ff\u96f7\u5229\u73e0\u55ae\u6297<\/p>\n

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\u524d\u77bb\u6027\u8072\u660e<\/p>\n

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\n

\u00a0 i.Desai J et al. Ann Oncol. 2017;28(suppl_5):v122\u2013v141.
\u00a0 ii. Zhang T et al. Cancer Immunol Immunother. 2018;67:1079\u20131090.
\u00a0 iii. Arlauckas SP et al. Sci Transl Med. 2017;9:eaal3604.
\u00a0 iv. Dahan R et al. Cancer Cell. 2015;28:285\u2013295.<\/span><\/p>\n<\/div>\n

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