{"id":13961,"date":"2023-08-02T11:39:00","date_gmt":"2023-08-02T03:39:00","guid":{"rendered":"https:\/\/www.franchise.com.hk\/%e7%99%be%e6%bf%9f%e7%a5%9e%e5%b7%9e2023%e5%b9%b4%e7%ac%ac%e4%ba%8c%e5%ad%a3%e5%ba%a6%e6%a5%ad%e7%b8%be%e5%a2%9e%e9%95%b7%e5%bc%b7%e5%8b%81%ef%bc%8c%e5%85%a8%e7%90%83%e5%8c%96%e7%99%bc%e5%b1%95\/13961"},"modified":"2023-08-02T11:39:00","modified_gmt":"2023-08-02T03:39:00","slug":"%e7%99%be%e6%bf%9f%e7%a5%9e%e5%b7%9e2023%e5%b9%b4%e7%ac%ac%e4%ba%8c%e5%ad%a3%e5%ba%a6%e6%a5%ad%e7%b8%be%e5%a2%9e%e9%95%b7%e5%bc%b7%e5%8b%81%ef%bc%8c%e5%85%a8%e7%90%83%e5%8c%96%e7%99%bc%e5%b1%95","status":"publish","type":"post","link":"https:\/\/www.franchise.com.hk\/zh-hans\/%e7%99%be%e6%bf%9f%e7%a5%9e%e5%b7%9e2023%e5%b9%b4%e7%ac%ac%e4%ba%8c%e5%ad%a3%e5%ba%a6%e6%a5%ad%e7%b8%be%e5%a2%9e%e9%95%b7%e5%bc%b7%e5%8b%81%ef%bc%8c%e5%85%a8%e7%90%83%e5%8c%96%e7%99%bc%e5%b1%95\/13961","title":{"rendered":"\u767e\u6fdf\u795e\u5dde2023\u5e74\u7b2c\u4e8c\u5b63\u5ea6\u696d\u7e3e\u589e\u9577\u5f37\u52c1\uff0c\u5168\u7403\u5316\u767c\u5c55\u52a0\u901f"},"content":{"rendered":"<p>\u5f97\u76ca\u65bc\u767e\u6085\u6fa4\u00ae\u5168\u7403\u92b7\u552e\u984d\u7684\u589e\u9577\uff0c\u672c\u5b63\u5ea6\u7522\u54c1\u6536\u5165\u90545.54\u5104\u7f8e\u5143\uff0c\u540c\u6bd4\u589e\u957782%<\/p>\n<p>\u672c\u5b63\u5ea6\u767e\u6085\u6fa4\u00ae\u5168\u7403\u92b7\u552e\u984d\u90543.08\u5104\u7f8e\u5143\uff0c\u540c\u6bd4\u589e\u9577139%\uff0c\u74b0\u6bd4\u589e\u957746%\uff1b\u516c\u53f8\u6301\u7e8c\u63a8\u9032\u767e\u6085\u6fa4\u00ae\u5728\u7f8e\u570b\u548c\u6b50\u76df\u7528\u65bc\u6cbb\u7642\u6162\u6027\u6dcb\u5df4\u7d30\u80de\u767d\u8840\u75c5\uff08CLL\uff09\u6210\u4eba\u60a3\u8005\u7684\u4e0a\u5e02\u5de5\u4f5c\uff0c\u978f\u56fa\u5176\u4f5c\u70ba\u9996\u9078BTK\u6291\u5236\u5291\u7684\u5730\u4f4d<\/p>\n<p>\u8209\u8fa6\u6295\u8cc7\u8005\u7814\u767c\u65e5\u6d3b\u52d5\uff0c\u5c55\u793a\u516c\u53f8\u65e5\u76ca\u589e\u9577\u3001\u591a\u6a23\u5316\u7684\u5275\u65b0\u7ba1\u7dda\u548c\u5dee\u7570\u5316\u7684\u7814\u767c\u7b56\u7565<\/p>\n<p><span class=\"legendSpanClass\">\u4e2d\u570b\u5317\u4eac\u3001\u7f8e\u570b\u9ebb\u7701\u528d\u6a4b\u548c\u745e\u58eb\u5df4\u585e\u723e<\/span><span class=\"legendSpanClass\">2023\u5e748\u67082\u65e5<\/span> \/\u7f8e\u901a\u793e\/ &#8212;\u00a0\u767e\u6fdf\u795e\u5dde\uff08\u7d0d\u65af\u9054\u514b\u4ee3\u78bc\uff1aBGNE\uff1b\u9999\u6e2f\u806f\u4ea4\u6240\u4ee3\u78bc\uff1a06160\uff1b\u4e0a\u4ea4\u6240\u4ee3\u78bc\uff1a688235\uff09\u662f\u4e00\u5bb6\u5168\u7403\u6027\u751f\u7269\u79d1\u6280\u516c\u53f8\uff0c\u516c\u53f8\u4eca\u65e5\u516c\u4f482023\u5e74\u7b2c\u4e8c\u5b63\u5ea6\u8ca1\u52d9\u696d\u7e3e\u548c\u696d\u52d9\u4eae\u9ede\u3002\u00a0<\/p>\n<p>\u767e\u6fdf\u795e\u5dde\u806f\u5408\u5275\u59cb\u4eba\u3001\u8463\u4e8b\u9577\u517c\u9996\u5e2d\u57f7\u884c\u5b98\u6b50\u96f7\u5f37\uff08John V. Oyler\uff09\u5148\u751f\u8868\u793a\uff1a\u300c\u6211\u5011\u5728\u7b2c\u4e8c\u5b63\u5ea6\u53d6\u5f97\u5f37\u52c1\u7684\u696d\u7e3e\u8868\u73fe\uff0c\u6301\u7e8c\u5f70\u986f\u4e86\u516c\u53f8\u5168\u7403\u5546\u696d\u5316\u5718\u968a\u7684\u57f7\u884c\u529b\uff0c\u4ee5\u53ca\u767e\u6085\u6fa4\u00ae\u548c\u767e\u6fa4\u5b89\u00ae\u9019\u5169\u6b3e\u57fa\u77f3\u85e5\u7269\u7684\u6210\u529f\u3002\u96a8\u8457CLL\u60a3\u8005\u8655\u65b9\u91cf\u4e0d\u65b7\u589e\u9577\uff0c\u767e\u6085\u6fa4\u00ae\u6191\u85c9\u5176\u5728\u591a\u9805\u9069\u61c9\u75c7\u4e2d\u4ee4\u4eba\u4fe1\u670d\u7684\u7642\u6548\u548c\u5b89\u5168\u6027\u6578\u64da\uff0c\u5305\u62ec\u5728\u5fa9\u767c\u6216\u96e3\u6cbb\u6027\uff08R\/R\uff09CLL\u5c0d\u6bd4\u5104\u73c2\u00ae\u53d6\u5f97\u7684\u512a\u6548\u6027\u7d50\u679c\uff0c\u6b63\u5728\u6210\u70ba\u9996\u9078BTK\u6291\u5236\u5291\u3002\u5728\u8fd1\u671f\u7684\u6295\u8cc7\u8005\u7814\u767c\u65e5\u6d3b\u52d5\u4e2d\uff0c\u6211\u5011\u5c55\u793a\u4e86\u516c\u53f8\u5728\u7814\u767c\u7ba1\u7dda\u4e0a\u5f37\u6709\u529b\u7684\u4f48\u5c40\u3002\u4f5c\u70ba\u4e00\u5bb6\u7acb\u8db3\u65bc\u79d1\u5b78\u7684\u516c\u53f8\uff0c\u767e\u6fdf\u795e\u5dde\u5efa\u7acb\u4e86\u696d\u5167\u898f\u6a21\u6700\u5927\u3001\u6700\u9ad8\u7522\u7684\u816b\u7624\u7814\u7a76\u5718\u968a\u4e4b\u4e00\uff0c\u6211\u5011\u7684\u7814\u767c\u7ba1\u7dda\u5c07\u6301\u7e8c\u63a8\u52d5\u516c\u53f8\u77ed\u671f\u8207\u9577\u671f\u7684\u767c\u5c55\uff0c\u9032\u800c\u66f4\u597d\u5730\u8e10\u884c\u6211\u5011\u70ba\u5168\u7403\u66f4\u591a\u60a3\u8005\u63d0\u4f9b\u5275\u65b0\u6027\u6297\u816b\u7624\u85e5\u7269\u3001\u6539\u5584\u6cbb\u7642\u9078\u64c7\u7684\u4f7f\u547d\u3002\u300d<\/p>\n<p>\u95dc\u9375\u696d\u52d9\u9032\u5c55\u548c\u7ba1\u7dda\u4eae\u9ede<\/p>\n<p>\u7372\u5f97\u6b50\u6d32\u85e5\u54c1\u7ba1\u7406\u5c40\uff08EMA\uff09\u4eba\u7528\u85e5\u54c1\u59d4\u54e1\u6703\uff08CHMP\uff09\u7684\u7a4d\u6975\u610f\u898b\uff0c\u652f\u6301\u767e\u6fa4\u5b89\u00ae\u7528\u65bc\u55ae\u85e5\u6cbb\u7642\u65e2\u5f80\u63a5\u53d7\u904e\u542b\u9251\u5316\u7642\u7684\u4e0d\u53ef\u5207\u9664\u3001\u5c40\u90e8\u665a\u671f\u6216\u8f49\u79fb\u6027\u98df\u7ba1\u9c57\u72c0\u7d30\u80de\u764c\uff08ESCC\uff09\u6210\u4eba\u60a3\u8005\u3002 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CLL\/\u5c0f\u6dcb\u5df4\u7d30\u80de\u6dcb\u5df4\u7624\uff08SLL\uff09\u3002   \u5ba3\u4f48\u767e\u6085\u6fa4\u00ae\u7372\u5f97\u4e2d\u570b\u570b\u5bb6\u85e5\u54c1\u76e3\u7763\u7ba1\u7406\u5c40\uff08NMPA\uff09\u591a\u9805\u65b0\u7684\u8a3b\u518a\u7533\u8acb\uff0c\u5305\u62ec\u5169\u9805sNDA\uff0c\u7528\u65bcTN CLL\/ SLL\u548c\u83ef\u6c0f\u5de8\u7403\u86cb\u767d\u8840\u75c7\uff08WM\uff09\u6210\u4eba\u60a3\u8005\uff0c\u4ee5\u53ca\u5169\u9805\u9644\u689d\u4ef6\u6279\u51c6\u8f49\u70ba\u5e38\u898f\u6279\u51c6\u7684\u88dc\u5145\u7533\u8acb\uff0c\u7528\u65bc\u6cbb\u7642\u7279\u5b9aR\/R CLL\/SLL\u548cR\/R WM\u60a3\u8005\u3002   \u8209\u8fa6\u6295\u8cc7\u8005\u7814\u767c\u65e5\u6d3b\u52d5\uff0c\u5c55\u793a\u516c\u53f8\u65e5\u76ca\u589e\u9577\u3001\u591a\u6a23\u5316\u7684\u5275\u65b0\u7ba1\u7dda\u7522\u54c1\u3002\u5982\u9700\u89c0\u770b\u91cd\u64ad\u8996\u983b\u3001\u77ad\u89e3\u66f4\u591a\u6d3b\u52d5\u4fe1\u606f\uff0c\u8acb\u8a2a\u554f\u767e\u6fdf\u795e\u5dde\u6295\u8cc7\u8005\u95dc\u4fc2\u7db2\u7ad9<a href=\"http:\/\/ir.beigene.com\/\" target=\"_blank\" rel=\"noopener\">http:\/\/ir.beigene.com<\/a>; <a href=\"https:\/\/hkexir.beigene.com\/\" target=\"_blank\" rel=\"noopener\">https:\/\/hkexir.beigene.com<\/a>; <a href=\"https:\/\/sseir.beigene.com\/\" target=\"_blank\" rel=\"noopener\">https:\/\/sseir.beigene.com<\/a>\u3002   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2023\u5e74\u7b2c\u4e8c\u5b63\u5ea6\uff0c\u767e\u6085\u6fa4\u00ae\u5728\u7f8e\u570b\u7684\u92b7\u552e\u984d\u70ba2.235\u5104\u7f8e\u5143\uff0c\u540c\u6bd4\u589e\u9577152.9%\uff0c\u4e3b\u8981\u5f97\u76ca\u65bc\u8a72\u7522\u54c1\u5728CLL\/SLL\u6210\u4eba\u60a3\u8005\u4e2d\u7684\u4f7f\u7528\u589e\u591a\uff0c\u4e14\u5728\u6240\u6709\u5df2\u7372FDA\u6279\u51c6\u7684\u9069\u61c9\u75c7\u4e2d\u7684\u61c9\u7528\u6301\u7e8c\u589e\u52a0\u3002\u5728\u4e2d\u570b\uff0c\u767e\u6085\u6fa4\u00ae\u672c\u5b63\u5ea6\u7684\u92b7\u552e\u984d\u70ba4,850\u842c\u7f8e\u5143\uff0c\u540c\u6bd4\u589e\u957732.2%\uff0c\u4e3b\u8981\u5f97\u76ca\u65bc\u6240\u6709\u5df2\u7372\u6279\u9069\u61c9\u75c7\u9818\u57df\u7684\u92b7\u552e\u984d\u589e\u9577\u3002\u516c\u53f8\u4f5c\u70ba\u4e2d\u570bBTK\u5e02\u5834\u7684\u9818\u8ecd\u4f01\u696d\uff0c\u5728\u9019\u4e00\u9818\u57df\u7684\u5e02\u5834\u4efd\u984d\u6301\u7e8c\u589e\u52a0\u3002   2023\u5e74\u7b2c\u4e8c\u5b63\u5ea6\uff0c\u767e\u6fa4\u5b89\u00ae\u5728\u4e2d\u570b\u7684\u92b7\u552e\u984d\u70ba1.495\u5104\u7f8e\u5143\uff0c\u540c\u6bd4\u589e\u957742.5%\u3002\u767e\u6fa4\u5b89\u00ae\u5e02\u5834\u6ef2\u900f\u7387\u7684\u63d0\u5347\uff0c\u4e26\u5728PD-1\u9818\u57df\u53d6\u5f97\u9818\u5148\u7684\u5e02\u5834\u4efd\u984d\uff0c\u4e3b\u8981\u5f97\u76ca\u65bc\u65b0\u9069\u61c9\u75c7\u7d0d\u5165\u91ab\u4fdd\u6240\u5e36\u4f86\u7684\u65b0\u589e\u60a3\u8005\u9700\u6c42\u3001\u92b7\u552e\u5718\u968a\u6548\u7387\u7684\u9032\u4e00\u6b65\u63d0\u5347\uff0c\u4ee5\u53ca\u85e5\u54c1\u9032\u9662\u6578\u91cf\u7684\u589e\u52a0\u3002   \u6309\u5730\u5340\u5283\u5206\uff0c\u7522\u54c1\u6536\u5165\u5177\u9ad4\u5982\u4e0b\uff08\u55ae\u4f4d\uff1a\u5343\u7f8e\u5143\uff09\uff1a  <\/p>\n<div>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u622a\u81f36\u670830\u65e5\u7684\u4e09\u500b\u6708<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u622a\u81f36\u670830\u65e5\u7684\u516d\u500b\u6708<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">2023\u5e74<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">2022\u5e74<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">2023\u5e74<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">2022\u5e74<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">$<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">$<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">$<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">$<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u4e2d\u570b<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">293,919<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">212,429<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">540,828<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">403,164<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u7f8e\u570b<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">223,540<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">88,381<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">362,307<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">156,269<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u5168\u7403\u5176\u4ed6\u5730\u5340<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">36,286<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">3,701<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">60,901<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">6,651<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u7e3d\u8a08<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">553,745<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">304,511<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">964,036<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">566,084<\/span><\/p>\n<\/div>\n<p>\u6bdb\u5229\u7387\uff1a2023\u5e74\u7b2c\u4e8c\u5b63\u5ea6\u7684\u6bdb\u5229\u5360\u5168\u7403\u7522\u54c1\u6536\u516582.7%\uff1b\u76f8\u6bd4\u8f03\uff0c\u4e0a\u4e00\u5e74\u540c\u671f\u70ba76.6%\u3002\u6bdb\u5229\u5360\u6bd4\u589e\u9577\u4e3b\u8981\u662f\u7531\u65bc\u767e\u6085\u6fa4\u00ae\u548c\u767e\u6fa4\u5b89\u00ae\u55ae\u4f4d\u6210\u672c\u8f03\u4f4e\uff0c\u4ee5\u53ca\u8207\u5176\u4ed6\u7522\u54c1\u7d44\u5408\u548c\u6bdb\u5229\u7387\u8f03\u4f4e\u7684\u6388\u6b0a\u8a31\u53ef\u7522\u54c1\u76f8\u6bd4\uff0c\u767e\u6085\u6fa4\u00ae\u5728\u5168\u7403\u92b7\u552e\u4e2d\u5360\u6bd4\u8f03\u9ad8\u3002<\/p>\n<p>\u7d93\u71df\u8cbb\u7528\uff1a\u622a\u81f32023\u5e746\u670830\u65e5\u7684\u4e09\u500b\u6708\u5167\uff0c\u7d93\u71df\u8cbb\u7528\u70ba8.18\u5104\u7f8e\u5143\uff1b\u76f8\u6bd4\u8f03\uff0c2022\u5e74\u540c\u671f\u8cbb\u7528\u70ba7.098\u5104\u7f8e\u5143\uff0c\u589e\u957715.2%\u3002\u800c\u7522\u54c1\u6536\u5165\u672c\u5b63\u5ea6\u540c\u6bd4\u589e\u957781.8%\uff0c\u7d93\u71df\u6760\u6746\u986f\u8457\u63d0\u5347\u3002<\/p>\n<p>\u6de8\u8667\u640d\uff1a\u622a\u81f32023\u5e746\u670830\u65e5\u7684\u7b2c\u4e8c\u5b63\u5ea6\u5167\uff0c\u6de8\u8667\u640d\u70ba3.811\u5104\u7f8e\u5143\uff0c\u5373\u6bcf\u80a1\u8667\u640d0.28\u7f8e\u5143\uff0c\u6bcf\u80a1\u7f8e\u570b\u5b58\u6258\u80a1\u4efd\uff08ADS\uff09\u8667\u640d3.64\u7f8e\u5143\uff1b\u76f8\u6bd4\u8f03\uff0c2022\u5e74\u540c\u671f\u6de8\u8667\u640d\u70ba5.657\u5104\u7f8e\u5143\uff0c\u5373\u6bcf\u80a1\u8667\u640d0.42\u7f8e\u5143\uff0c\u6bcf\u80a1ADS\u8667\u640d5.50\u7f8e\u5143\u3002\u6de8\u8667\u640d\u6e1b\u5c11\u4e3b\u8981\u56e0\u70ba\u7522\u54c1\u6536\u5165\u589e\u9577\u8d85\u904e\u4e86\u7d93\u71df\u8cbb\u7528\u589e\u9577\uff0c\u5f9e\u800c\u63d0\u9ad8\u4e86\u7d93\u71df\u6760\u6746\u3002\u516c\u53f8\u9810\u8a08\u5c07\u57282023\u5e74\u7e7c\u7e8c\u4fdd\u6301\u9019\u4e00\u8da8\u52e2\u3002\u672c\u5b63\u5ea6\u6de8\u8667\u640d\u9084\u5305\u62ec\u975e\u7d93\u71df\u8cbb\u75286,380\u842c\u7f8e\u5143\uff0c\u8a72\u90e8\u5206\u975e\u7d93\u71df\u6027\u8cbb\u7528\u4e3b\u8981\u4f86\u81ea\u4e8e\u7f8e\u5143\u8d70\u5f37\uff0c\u4ee5\u53ca\u6309\u7f8e\u5143\u8a08\u50f9\u5b50\u516c\u53f8\u6240\u6301\u5916\u5e63\u8ca8\u5e63\u50f9\u503c\u91cd\u4f30\u6240\u9304\u5f97\u7684\u532f\u514c\u640d\u5931\u30022022\u5e74\u540c\u671f\u975e\u7d93\u71df\u6027\u8cbb\u7528\u70ba1.296\u5104\u7f8e\u5143\u3002<\/p>\n<p>\u73fe\u91d1\u3001\u73fe\u91d1\u7b49\u50f9\u7269\u3001\u53d7\u9650\u8cc7\u91d1\u548c\u77ed\u671f\u6295\u8cc7\uff1a\u622a\u81f32023\u5e746\u670830\u65e5\u70ba35\u5104\u7f8e\u5143\uff1b\u76f8\u6bd4\u8f03\uff0c\u622a\u81f32022\u5e7412\u670831\u65e5\uff0c\u8a72\u90e8\u5206\u8cc7\u91d1\u70ba45\u5104\u7f8e\u5143\u3002\u00a0<\/p>\n<p>\u6709\u95dc\u516c\u53f82023\u5e74\u7b2c\u4e8c\u5b63\u5ea6\u8ca1\u52d9\u5831\u8868\u7684\u66f4\u591a\u8a73\u7d30\u4fe1\u606f\uff0c\u8acb\u53c3\u95b1\u767e\u6fdf\u795e\u5dde\u5411\u7f8e\u570b\u8b49\u5238\u4ea4\u6613\u59d4\u54e1\u6703\u63d0\u4ea4\u76842023\u5e74\u7b2c\u4e8c\u5b63\u5ea6\u5831\u544a\u768410-Q\u8868\u683c\u3002<\/p>\n<p>\u8a3b\u518a\u9032\u5c55\u548c\u958b\u767c\u9805\u76ee<\/p>\n<div>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u985e\u5225<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u7522\u54c1<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u8fd1\u671f\u91cc\u7a0b\u7891\u4e8b\u4ef6<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u7372\u6279\u00a0\/ \u8a3b\u518a\u9032\u5c55<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u767e\u6085\u6fa4\u00ae<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">(\u6fa4\u5e03\u66ff\u5c3c)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u00a0<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u2022\u00a0 <\/span><span class=\"prnews_span\">\u7372\u5f97\u52a0\u62ff\u5927\u885b\u751f\u90e8\u6279\u51c6\uff0c\u7528\u65bc\u6cbb\u7642<\/span><span class=\"prnews_span\">CLL\/SLL<\/span><span class=\"prnews_span\">\u6210\u4eba\u60a3\u8005<\/span><span class=\"prnews_span\"> <\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u2022\u00a0 <\/span><span class=\"prnews_span\">\u7372\u5f97\u6fb3\u5927\u5229\u4e9e\u85e5\u54c1\u7ba1\u7406\u5c40\u6279\u51c6\uff0c\u7528\u65bc\u6cbb\u7642<\/span><span class=\"prnews_span\">TN<\/span><span class=\"prnews_span\">\u548c<\/span><span class=\"prnews_span\">R\/R <br \/>\u00a0 \u00a0CLL\/SLL<\/span><span class=\"prnews_span\">\u60a3\u8005<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u2022\u00a0 <\/span><span class=\"prnews_span\">\u7372\u5f97\u4e2d\u570b<\/span><span class=\"prnews_span\">NMPA<\/span><span class=\"prnews_span\">\u6279\u51c6\uff1a<\/span><span class=\"prnews_span\"> <\/span><\/p>\n<p class=\"prnml70\"><span class=\"prnews_span\">o\u00a0 <\/span><span class=\"prnews_span\">\u65b0\u589e\u9069\u61c9\u75c7\u4e0a\u5e02\u8a31\u53ef\u7533\u8acb\uff0c\u7528\u65bc\u6cbb\u7642<\/span><span class=\"prnews_span\">TN <br \/>\u00a0 \u00a0 CLL\/SLL<\/span><span class=\"prnews_span\">\u6210\u4eba\u60a3\u8005<\/span><\/p>\n<p class=\"prnml70\"><span class=\"prnews_span\">o\u00a0 <\/span><span class=\"prnews_span\">\u65b0\u589e\u9069\u61c9\u75c7\u4e0a\u5e02\u8a31\u53ef\u7533\u8acb\uff0c\u7528\u65bc\u6cbb\u7642<\/span><span class=\"prnews_span\">TN WM\u00a0<br \/><\/span><span class=\"prnews_span\">\u00a0 \u00a0 \u6210\u4eba\u60a3\u8005<\/span><\/p>\n<p class=\"prnml70\"><span class=\"prnews_span\">o\u00a0 <\/span><span class=\"prnews_span\">\u7531\u9644\u689d\u4ef6\u6279\u51c6\u8f49\u70ba\u5e38\u898f\u6279\u51c6\uff0c\u7528\u65bc\u6cbb\u7642<\/span><span class=\"prnews_span\">R\/R <br \/>\u00a0 \u00a0 CLL\/SLL<\/span><span class=\"prnews_span\">\u6210\u4eba\u60a3\u8005<\/span><\/p>\n<p class=\"prnml70\"><span class=\"prnews_span\">o\u00a0 <\/span><span class=\"prnews_span\">\u7531\u9644\u689d\u4ef6\u6279\u51c6\u8f49\u70ba\u5e38\u898f\u6279\u51c6\uff0c\u7528\u65bc\u6cbb\u7642\u6210\u4eba\u00a0<br \/><\/span><span class=\"prnews_span\">\u00a0 \u00a0 R\/R WM<\/span><span class=\"prnews_span\">\u60a3\u8005<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u00a0<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u767e\u6fa4\u5b89\u00ae<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\uff08\u66ff\u96f7\u5229\u73e0\u55ae\u6297\uff09<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u2022\u00a0 <\/span><span class=\"prnews_span\">\u7372\u5f97<\/span><span class=\"prnews_span\">EMA CHMP<\/span><span class=\"prnews_span\">\u7684\u7a4d\u6975\u610f\u898b\uff0c\u652f\u6301\u767e\u6fa4\u5b89<\/span>\u00ae<span class=\"prnews_span\">\u7528\u65bc\u6cbb\u7642\u65e2\u5f80<br \/>\u00a0 \u00a0\u63a5\u53d7\u904e\u542b\u9251\u5316\u7642\u7684\u4e0d\u53ef\u5207\u9664\u3001\u5c40\u90e8\u665a\u671f\u6216\u8f49\u79fb\u6027<\/span><span class=\"prnews_span\">ESCC<\/span><span class=\"prnews_span\">\u6210<br \/>\u00a0 \u4eba\u60a3\u8005<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u2022\u00a0 <\/span><span class=\"prnews_span\">\u7372\u5f97\u4e2d\u570b<\/span><span class=\"prnews_span\">NMPA<\/span><span class=\"prnews_span\">\u6279\u51c6\uff1a<\/span><span class=\"prnews_span\"> <\/span><\/p>\n<p class=\"prnml40\"><span class=\"prnews_span\">o\u00a0 <\/span><span class=\"prnews_span\">\u7528\u65bc\u4e00\u7dda\u6cbb\u7642\u80c3\u764c\u6210\u4eba\u60a3\u8005\uff08<\/span><span class=\"prnews_span\">PD-L1<\/span><span class=\"prnews_span\">\u967d\u6027\uff09<\/span><span class=\"prnews_span\"> <\/span><\/p>\n<p class=\"prnml40\"><span class=\"prnews_span\">o\u00a0 <\/span><span class=\"prnews_span\">\u7528\u65bc\u4e00\u7dda\u6cbb\u7642<\/span><span class=\"prnews_span\">ESCC<\/span><span class=\"prnews_span\">\u6210\u4eba\u60a3\u8005<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u767e\u62d3\u7dad<\/span><span class=\"prnews_span\">\u00ae<\/span><span class=\"prnews_span\">\uff08\u6ce8\u5c04<br \/>\u7528\u6208\u820d\u745e\u6797\u5fae<br \/>\u7403\uff09<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u00a0<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u2022\u00a0 <\/span><span class=\"prnews_span\">\u8207\u7da0\u8449\u5236\u85e5\u5408\u4f5c\uff0c\u7372\u5f97\u4e2d\u570b<\/span><span class=\"prnews_span\">NMPA<\/span><span class=\"prnews_span\">\u6279\u51c6\uff0c\u7528\u65bc\u9700\u8981\u96c4<br \/>\u00a0 \u00a0\u6fc0\u7d20\u53bb\u52e2\u6cbb\u7642\u7684\u524d\u5217\u817a\u764c\u60a3\u8005<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u8a3b\u518a\u7533\u5831<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u767e\u6085\u6fa4\u00ae<\/span><\/p>\n<p class=\"prnml20\"><span class=\"prnews_span\">\u2022\u00a0 <\/span><span class=\"prnews_span\">\u7528\u65bc\u6cbb\u7642<\/span><span class=\"prnews_span\">R\/R FL<\/span><span class=\"prnews_span\">\u6210\u4eba\u60a3\u8005\u7684<\/span><span class=\"prnews_span\">sNDA<\/span><span class=\"prnews_span\">\u5df2\u7372<\/span><span class=\"prnews_span\">FDA<\/span><span class=\"prnews_span\">\u53d7\u7406<\/span><\/p>\n<p class=\"prnml20\"><span class=\"prnews_span\">\u2022\u00a0 <\/span><span class=\"prnews_span\">\u7528\u65bc\u6cbb\u7642<\/span><span class=\"prnews_span\">R\/R FL<\/span><span class=\"prnews_span\">\u6210\u4eba\u60a3\u8005\u7684\u4e0a\u5e02\u8a31\u53ef\u7533\u8acb\uff08<\/span><span class=\"prnews_span\">MAA<\/span><span class=\"prnews_span\">\uff09\u5df2<br \/>\u00a0 \u00a0\u7372<\/span><span class=\"prnews_span\">EMA<\/span><span class=\"prnews_span\">\u53d7\u7406<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u81e8\u5e8a\u958b\u767c\u9032\u5c55<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u767e\u6085\u6fa4\u00ae<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u2022\u00a0 <\/span><span class=\"prnews_span\">\u7528\u65bc\u6cbb\u7642\u539f\u767c\u6027\u819c\u6027\u814e\u75c5\u7684<\/span><span class=\"prnews_span\">3<\/span><span class=\"prnews_span\">\u671f\u81e8\u5e8a\u8a66\u9a57\u5b8c\u6210\u9996\u4f8b\u60a3<br \/>\u00a0 \u00a0\u8005\u5165\u7d44<\/span><\/p>\n<\/div>\n<p>\u00a0<\/p>\n<p>\u9810\u8a08\u91cc\u7a0b\u7891\u4e8b\u4ef6<\/p>\n<div>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u985e\u5225<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u7522\u54c1<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u9810\u8a08\u91cc\u7a0b\u7891\u4e8b\u4ef6<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u7372\u6279\u00a0\/ \u8a3b\u518a\u9032\u5c55<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u767e\u6fa4\u5b89\u00ae<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u2022\u00a0 <\/span><span class=\"prnews_span\">\u8207\u8afe\u83ef\u5408\u4f5c\uff0c\u652f\u6301\u5728\u7f8e\u570b<\/span>[*]<span class=\"prnews_span\">\u548c\u6b50\u76df\u7528\u65bc\u4e8c\u7dda\u6cbb\u7642<\/span><span class=\"prnews_span\">ESCC<\/span><span class=\"prnews_span\">\u7684\u65b0\u85e5<br \/>\u00a0 \u4e0a\u5e02\u7533\u8acb\u7684\u8a3b\u518a\u5de5\u4f5c<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u00a0<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u8a3b\u518a\u7533\u5831<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u767e\u6fa4\u5b89\u00ae<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u2022\u00a0 <\/span><span class=\"prnews_span\">\u5728\u4e2d\u570b\u905e\u4ea4\u7528\u65bc\u4e00\u7dda\u6cbb\u7642\u5ee3\u6cdb\u671f\u5c0f\u7d30\u80de\u80ba\u764c\uff08<\/span><span class=\"prnews_span\">ES-SCLC<\/span><span class=\"prnews_span\">\uff09\u7684<br \/>\u00a0 \u00a0\u8a3b\u518a\u7533\u5831\u5de5\u4f5c<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u2022\u00a0 <\/span><span class=\"prnews_span\">\u8207\u8afe\u83ef\u5408\u4f5c\uff0c\u652f\u6301\u5728\u7f8e\u570b\u548c\u6b50\u76df\u7528\u65bc\u4e00\u7dda\u6cbb\u7642<\/span><span class=\"prnews_span\">ESCC<\/span><span class=\"prnews_span\">\u7684\u8a3b\u518a<br \/>\u00a0 \u00a0\u7533\u5831\u5de5\u4f5c<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u2022\u00a0 <\/span><span class=\"prnews_span\">\u8207\u8afe\u83ef\u5408\u4f5c\uff0c\u652f\u6301\u5728\u7f8e\u570b\u548c\u6b50\u76df\u7528\u65bc\u4e00\u7dda\u6cbb\u7642\u80c3\u764c\u7684\u8a3b\u518a<br \/>\u00a0 \u00a0\u7533\u5831\u5de5\u4f5c<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u2022\u00a0 <\/span><span class=\"prnews_span\">\u8207\u8afe\u83ef\u5408\u4f5c\uff0c\u652f\u6301\u5728\u65e5\u672c\u7528\u65bc\u4e00\u7dda\u3001\u4e8c\u7dda\u6cbb\u7642<\/span><span class=\"prnews_span\">ESCC<\/span><span class=\"prnews_span\">\u7684\u8a3b\u518a<br \/>\u00a0 \u00a0\u7533\u5831\u5de5\u4f5c<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u81e8\u5e8a\u958b\u767c\u9032\u5c55\u00a0\/ <br \/>\u6578\u64da\u8b80\u51fa<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u767e\u6085\u6fa4\u00ae<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u2022\u00a0 <\/span><span class=\"prnews_span\">\u516c\u4f48\u767e\u6085\u6fa4<\/span>\u00ae<span class=\"prnews_span\">\u5c0d\u6bd4\u5104\u73c2<\/span>\u00ae<span class=\"prnews_span\">\u6cbb\u7642<\/span><span class=\"prnews_span\">R\/R CLL<\/span><span class=\"prnews_span\">\u7684<\/span><span class=\"prnews_span\">3<\/span><span class=\"prnews_span\">\u671f<\/span><span class=\"prnews_span\">ALPINE<\/span><span class=\"prnews_span\">\u8a66\u9a57\u66f4<br \/>\u00a0 \u00a0\u9577\u96a8\u8a2a\u671f\u7684\u6578\u64da<\/span><\/p>\n<p class=\"prnml4\">\u00a0<\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u767e\u6fa4\u5b89\u00ae<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u00a0<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u2022\u00a0 <\/span><span class=\"prnews_span\">\u516c\u4f48\u65b0\u8f14\u52a9\u6cbb\u7642\u548c\u8f14\u52a9\u6cbb\u7642\u975e\u5c0f\u7d30\u80de\u80ba\u764c<\/span><span class=\"prnews_span\"> (NSCLC) <\/span><span class=\"prnews_span\">\u7684<\/span><span class=\"prnews_span\"> 3 <\/span><span class=\"prnews_span\">\u671f\u00a0<br \/><\/span><span class=\"prnews_span\">\u00a0 \u00a0 RATIONALE-315 <\/span><span class=\"prnews_span\">\u8a66\u9a57\u7d50\u679c<\/span><\/p>\n<p class=\"prnml4\">\u00a0<\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">Sonrotoclax\uff08BCL-<br \/>2\u6291\u5236\u5291BGB-<br \/>11417\uff09<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u00a0<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u2022\u00a0 <\/span><span class=\"prnews_span\">\u5c07\u4e8e<\/span><span class=\"prnews_span\">2023<\/span><span class=\"prnews_span\">\u5e74\u4e0b\u534a\u5e74\u555f\u52d5\u806f\u5408\u767e\u6085\u6fa4<\/span>\u00ae<span class=\"prnews_span\">\u7528\u65bc\u4e00\u7dda\u6cbb\u7642<\/span><span class=\"prnews_span\">CLL<\/span><span class=\"prnews_span\">\u7684\u5168<br \/>\u00a0 \u00a0\u7403\u95dc\u9375\u6027\u8a66\u9a57<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u2022\u00a0 <\/span><span class=\"prnews_span\">\u5c07\u65bc<\/span><span class=\"prnews_span\">2023<\/span><span class=\"prnews_span\">\u5e74\u4e0b\u534a\u5e74\u555f\u52d5\u6cbb\u7642<\/span><span class=\"prnews_span\">R\/R WM<\/span><span class=\"prnews_span\">\u7684\u6f5b\u5728\u8a3b\u518a\u53ef\u7528\u7684\u5168<br \/>\u00a0 \u00a0\u7403\u8a66\u9a57<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u2022\u00a0 <\/span><span class=\"prnews_span\">\u516c\u4f48<\/span><span class=\"prnews_span\">1<\/span><span class=\"prnews_span\">\u671f\u8a66\u9a57\u7684\u6700\u65b0\u6578\u64da\u7d50\u679c<\/span><\/p>\n<p class=\"prnml4\">\u00a0<\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">BTK CDAC (BGB-<br \/>16673)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u2022\u00a0 <\/span><span class=\"prnews_span\">\u516c\u4f48\u6cbb\u7642<\/span><span class=\"prnews_span\">B<\/span><span class=\"prnews_span\">\u7d30\u80de\u60e1\u6027\u816b\u7624\u7684<\/span><span class=\"prnews_span\">1<\/span><span class=\"prnews_span\">\u671f\u8a66\u9a57\u6700\u65b0\u6578\u64da\u7d50\u679c<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u6b50\u53f8\u73c0\u5229\u55ae\u6297\uff08\u6297<br \/>TIGIT\u6297\u9ad4\uff09<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u00a0<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u2022\u00a0 <\/span><span class=\"prnews_span\">\u5c07\u65bc<\/span><span class=\"prnews_span\">2023<\/span><span class=\"prnews_span\">\u5e74\u5b8c\u6210\u4e00\u7dda\u6cbb\u7642<\/span><span class=\"prnews_span\">NSCLC<\/span><span class=\"prnews_span\">\u7684<\/span><span class=\"prnews_span\">3<\/span><span class=\"prnews_span\">\u671f\u8a66\u9a57<\/span><span class=\"prnews_span\">AdvanTIG-302\u00a0<br \/><\/span><span class=\"prnews_span\">\u00a0 \u00a0\u7684\u5165\u7d44\u5de5\u4f5c<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u2022\u00a0 <\/span><span class=\"prnews_span\">\u516c\u4f48\u591a\u9805<\/span><span class=\"prnews_span\">2<\/span><span class=\"prnews_span\">\u671f\u8a66\u9a57\u6578\u64da\uff0c\u5305\u62ec\uff1a<\/span><\/p>\n<p class=\"prnml70\"><span class=\"prnews_span\">o\u00a0 <\/span><span class=\"prnews_span\">\u7528\u65bc\u4e8c\u7dda\u6cbb\u7642\u816b\u7624\u8868\u9054<\/span><span class=\"prnews_span\"> PD-(L)1 <\/span><span class=\"prnews_span\">\u7684<\/span><span class=\"prnews_span\">ESCC<\/span><\/p>\n<p class=\"prnml70\"><span class=\"prnews_span\">o\u00a0 <\/span><span class=\"prnews_span\">\u7528\u65bc\u4e00\u7dda\u6cbb\u7642\u809d\u7d30\u80de\u764c<\/span><span class=\"prnews_span\">(HCC)<\/span><\/p>\n<p class=\"prnml70\"><span class=\"prnews_span\">o\u00a0 <\/span><span class=\"prnews_span\">\u7528\u65bc\u4e00\u7dda\u6cbb\u7642<\/span><span class=\"prnews_span\">NSCLC<\/span><\/p>\n<p class=\"prnml4\">\u00a0<\/p>\n<\/div>\n<p><span>[*]\u539f\u6709PDUFA\u65e5\u671f\u5ef6\u9577<\/span><\/p>\n<p>\u79d1\u7814\u5b78\u8853\u5927\u6703\u9032\u5c55<\/p>\n<p>\u5c07\u57289\u6708\u4efd\u8209\u884c\u7684 2023 \u5e74\u4e16\u754c\u80ba\u764c\u5927\u6703\u4e0a\uff0c\u53e3\u982d\u5831\u544a\u767e\u6fa4\u5b89\u00ae\u806f\u5408\u6216\u4e0d\u806f\u5408\u5316\u7642\u6cbb\u7642\u5ee3\u6cdb\u671f\u5c0f\u7d30\u80de\u80ba\u764c\u76843 \u671f RATIONALE-312 \u8a66\u9a57\u7d50\u679c\u3002   \u5c07\u5728 10 \u6708\u4efd\u8209\u884c\u7684\u6b50\u6d32\u816b\u7624\u5167\u79d1\u5b78\u6703 (ESMO) \u5e74\u6703\u4e0a\uff0c\u5c55\u793a 8 \u7bc7\u6458\u8981\uff0c\u5305\u62ec\u767e\u6fa4\u5b89\u00ae\u3001\u6b50\u53f8\u73c0\u5229\u55ae\u6297\u4ee5\u53ca\u5176\u4ed6\u5be6\u9ad4\u7624\u9805\u76ee\u7684\u6578\u64da\u3002   \u5728\u7f8e\u570b\u81e8\u5e8a\u816b\u7624\u5b78\u6703\uff08ASCO\uff09\u5e74\u6703\u548c\u6b50\u6d32\u8840\u6db2\u5b78\u5354\u6703\uff08EHA\uff09\u5927\u6703\u4e0a\uff0c\u516c\u4f48\u767e\u6085\u6fa4\u00ae\u81e8\u5e8a\u8a66\u9a57\u7d50\u679c\uff0c\u5305\u62ec\u7528\u65bc\u6cbb\u7642R\/R\u5f4c\u6f2b\u6027\u5927B\u7d30\u80de\u6dcb\u5df4\u7624\uff08DLBCL\uff09\u76841\u671f\u7814\u7a76\u7d50\u679c\uff0c\u4ee5\u53ca\u8207\u4f73\u7f85\u83ef\u00ae\u806f\u7528\uff0c\u6cbb\u7642R\/R FL\u76843\u671fROSEWOOD\u8a66\u9a57\u7684\u6700\u65b0\u7814\u7a76\u7d50\u679c\u3002   \u5728ASCO\u5e74\u6703\u4e0a\uff0c\u5c55\u793a\u767e\u6fa4\u5b89\u00ae\u5169\u7bc7\u6458\u8981\uff0c\u5305\u62ec\u57283\u671fRATIONALE 301\u8a66\u9a57\u4e2d\uff0c\u5c0d\u6bd4\u7d22\u62c9\u975e\u5c3c\uff0c\u6cbb\u7642\u4e00\u7dda\u4e0d\u53ef\u5207\u9664\u809d\u7d30\u80de\u764c\uff08HCC\uff09\u7684\u88dc\u5145\u5206\u6790\uff1b   \u5728ASCO\u5e74\u6703\u4e0a\uff0c\u516c\u4f48\u81ea\u7814OX40\u6fc0\u52d5\u5291BGB-A445\u4e00\u98051\u671f\u7814\u7a76\u7d50\u679c\uff0c\u806f\u5408\u6216\u4e0d\u806f\u5408\u767e\u6fa4\u5b89\u00ae\uff0c\u6cbb\u7642\u665a\u671f\u5be6\u9ad4\u7624\u60a3\u8005\u3002   \u8207Zymeworks\u5408\u4f5c\uff0c\u5728ASCO\u5e74\u6703\u4e0a\u53e3\u982d\u5831\u544azanidatamab\u7528\u65bc\u6cbb\u7642\u65e2\u5f80\u7d93\u6cbb\u7684HER2\u57fa\u56e0\u64f4\u589e\u81bd\u9053\u764c2b\u671fHERIZON-BTC\u7814\u7a76\u7684\u6700\u65b0\u7d50\u679c\u3002  <\/p>\n<p>\u751f\u7522\u904b\u71df<\/p>\n<p>\u7e7c\u7e8c\u5efa\u8a2d\u4f4d\u65bc\u7f8e\u570b\u65b0\u6fa4\u897f\u5dde\u970d\u666e\u97cb\u723e\u666e\u6797\u65af\u9813\u897f\u90e8\u5275\u65b0\u5712\u5340\u7684\u65d7\u8266\u7d1a\u751f\u7522\u57fa\u5730\u548c\u81e8\u5e8a\u7814\u767c\u4e2d\u5fc3\uff0c\u8017\u8cc7\u8d85\u904e7\u5104\u7f8e\u5143\u3002\u8a72\u57fa\u5730\u9810\u7559\u4e86\u8d85\u904e100\u842c\u5e73\u65b9\u82f1\u5c3a\uff08\u7d049.3\u842c\u5e73\u65b9\u7c73\uff09\u7684\u53ef\u958b\u767c\u5730\u7522\uff0c\u4ee5\u5099\u7528\u4e8e\u672a\u4f86\u7684\u9032\u4e00\u6b65\u62d3\u5c55\u3002\u57fa\u5730\u9810\u8a08\u5c07\u65bc2024\u5e74\u5b8c\u5de5\u3002   \u7e7c\u7e8c\u5efa\u8a2d\u4f4d\u65bc\u4e2d\u570b\u5ee3\u5dde\u7684\u4e16\u754c\u4e00\u6d41\u751f\u7269\u85e5\u751f\u7522\u57fa\u5730\uff0c\u76ee\u524d\u7e3d\u7522\u80fd\u5df2\u905464,000\u5347\uff0c\u5305\u62ec\u4e00\u6b21\u6027\u53cd\u61c9\u5668\u548c\u4e0d\u92b9\u92fc\u53cd\u61c9\u5668\u6280\u8853\u3002\u8a72\u57fa\u5730\u5c07\u7e7c\u7e8c\u5efa\u8a2d\u6297\u9ad4\u5076\u806f\u85e5\u7269\uff08ADC\uff09\u751f\u7522\u8a2d\u65bd\u548c\u5168\u65b0\u751f\u7269\u85e5\u81e8\u5e8a\u751f\u7522\u5927\u6a13\uff0c\u9810\u8a08\u5c07\u65bc2024\u5e74\u5b8c\u5de5\u3002   \u7e7c\u7e8c\u5efa\u8a2d\u4f4d\u65bc\u4e2d\u570b\u8607\u5dde\u7684\u65b0\u5efa\u5c0f\u5206\u5b50\u5275\u65b0\u85e5\u7269\u7522\u696d\u5316\u57fa\u5730\u3002\u7b2c\u4e00\u968e\u6bb5\u7684\u5efa\u8a2d\u9762\u7a4d\u9810\u8a08\u5c07\u8d85\u904e55.9\u842c\u5e73\u65b9\u82f1\u5c3a\uff08\u7d045.2\u842c\u5e73\u65b9\u7c73\uff09\uff0c\u56fa\u9ad4\u5236\u5291\u7522\u80fd\u53ef\u64f4\u5927\u81f3\u6bcf\u5e746\u5104\u7247\uff08\u7c92\uff09\u5291\u6b21\uff0c\u8a72\u9805\u76ee\u9810\u8a08\u5c07\u65bc2023\u5e74\u5167\u5b8c\u5de5\u3002\u5f85\u57fa\u5730\u5efa\u8a2d\u5b8c\u6210\u3001\u9a57\u6536\u5408\u683c\u4e26\u7372\u6279\u5f8c\uff0c\u9810\u8a08\u6211\u5011\u5728\u4e2d\u570b\u7684\u5c0f\u5206\u5b50\u85e5\u7269\u751f\u7522\u80fd\u529b\u5c07\u63d0\u5347\u81f3\u76ee\u524d\u76845\u500d\u4ee5\u4e0a\u3002\u6b64\u5916\uff0c\u4f4d\u65bc\u8607\u5dde\u7684\u65b0\u7814\u767c\u4e2d\u5fc3\u4e5f\u5df2\u7d93\u555f\u52d5\u5efa\u8a2d\uff0c\u4ee5\u63d0\u9ad8\u81e8\u5e8a\u548c\u751f\u7522\u80fd\u529b\uff0c\u8a72\u7814\u767c\u4e2d\u5fc3\u9810\u8a08\u5c07\u65bc2024\u5e74\u5b8c\u5de5\u3002  <\/p>\n<p>\u4f01\u696d\u767c\u5c55<\/p>\n<p>\u767e\u6fdf\u795e\u5dde\u91cd\u65b0\u7372\u5f97\u4e86\u958b\u767c\u3001\u751f\u7522\u548c\u5546\u696d\u5316\u5728\u7814TIGIT\u6291\u5236\u5291\u6b50\u53f8\u73c0\u5229\u55ae\u6297\u7684\u5168\u90e8\u5168\u7403\u6b0a\u5229\u3002\u767e\u6fdf\u795e\u5dde\u8207\u8afe\u83ef\u5171\u540c\u6c7a\u5b9a\u7d42\u6b62\u300a\u9078\u64c7\u6b0a\u3001\u5408\u4f5c\u548c\u6388\u6b0a\u5408\u7d04\u300b\uff0c\u767e\u6fdf\u795e\u5dde\u5148\u524d\u6839\u64da\u8a72\u5354\u5b9a\u6388\u4e88\u8afe\u83ef\u4e00\u9805\u7368\u5bb6\u7684\u3001\u57fa\u65bc\u6642\u9593\u7684\u9078\u64c7\u6b0a\uff0c\u4ee5\u4f7f\u8afe\u83ef\u53ef\u4ee5\u901a\u904e\u884c\u4f7f\u8a72\u9078\u64c7\u6b0a\u7372\u5f97\u6b50\u53f8\u73c0\u5229\u55ae\u6297\u5728\u5317\u7f8e\u3001\u6b50\u6d32\u548c\u65e5\u672c\u7684\u958b\u767c\u3001\u751f\u7522\u548c\u5546\u696d\u5316\u6b0a\u5229\u3002   \u8207\u7da0\u8449\u5236\u85e5\u5408\u4f5c\uff0c\u5728\u4e2d\u570b\u5546\u696d\u5316\u767e\u62d3\u7dad\u00ae\uff08\u6ce8\u5c04\u7528\u6208\u820d\u745e\u6797\u5fae\u7403\uff09\uff0c\u7528\u65bc\u9700\u8981\u9032\u884c\u96c4\u6fc0\u7d20\u53bb\u52e2\u6cbb\u7642\u7684\u524d\u5217\u817a\u764c\u60a3\u8005\uff0c\u9032\u4e00\u6b65\u64f4\u5927\u516c\u53f8\u5728\u5c3f\u8def\u4e0a\u76ae\u764c\u9069\u61c9\u75c7\u9818\u57df\u7684\u4f48\u5c40\u3002  <\/p>\n<p>\u8ca1\u52d9\u6458\u8981<\/p>\n<p>\u7c21\u660e\u5408\u4f75\u8cc7\u7522\u8ca0\u50b5\u8868\u6458\u8981\u6578\u64da\uff08\u7f8e\u570b\u516c\u8a8d\u6703\u8a08\u6e96\u5247\uff09<\/p>\n<p>\uff08\u55ae\u4f4d\uff1a\u5343\u7f8e\u5143\uff09<\/p>\n<div>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u622a\u81f3<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">2023\u5e74<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">2022\u5e74\u00a0<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">6\u670830\u65e5<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">12\u670831\u65e5<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\uff08\u672a\u7d93\u5be9\u8a08\uff09<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\uff08\u7d93\u5be9\u8a08\uff09<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u8cc7\u7522\uff1a<\/span><\/p>\n<p>     <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u73fe\u91d1\u3001\u73fe\u91d1\u7b49\u50f9\u7269\u3001\u53d7\u9650\u8cc7\u91d1\u548c\u77ed\u671f\u6295\u8cc7<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">$\u00a0\u00a0\u00a0\u00a0\u00a0 3,527,267<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">$\u00a0\u00a0\u00a0\u00a0\u00a0 4,540,288<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u61c9\u6536\u8cec\u6b3e\u6de8\u984d<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">299,282<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">173,168<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u5b58\u8ca8<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">321,333<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">282,346<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u7269\u696d\uff0c\u5ee0\u623f\u53ca\u8a2d\u5099\uff0c\u6de8\u984d<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">1,031,938<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">845,946<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u7e3d\u8cc7\u7522<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">5,728,736<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">6,379,290<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u8ca0\u50b5\u53ca\u6240\u6709\u8005\u6b0a\u76ca\uff1a<\/span><\/p>\n<p>     <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u61c9\u4ed8\u5e33\u6b3e<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">266,975<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">294,781<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u9810\u63d0\u8cbb\u7528\u53ca\u5176\u4ed6\u61c9\u4ed8\u6b3e\u9805<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">454,950<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">467,352<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u905e\u5ef6\u6536\u5165<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">183,310<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">255,887<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u7814\u767c\u6210\u672c\u5206\u6524\u8ca0\u50b5<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">271,291<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">293,960<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u501f\u6b3e<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">628,478<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">538,117<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u7e3d\u8ca0\u50b5<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">1,930,177<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">1,995,935<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u6240\u6709\u8005\u6b0a\u76ca\u5408\u8a08<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">$\u00a0\u00a0\u00a0\u00a0\u00a0 3,798,559<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">$\u00a0\u00a0\u00a0\u00a0\u00a0 4,383,355<\/span><\/p>\n<\/div>\n<p>\u00a0<\/p>\n<p>\u7c21\u660e\u5408\u4f75\u640d\u76ca\u8868\uff08\u7f8e\u570b\u516c\u8a8d\u6703\u8a08\u6e96\u5247\uff09<\/p>\n<p>\uff08\u9664\u666e\u901a\u80a1\u6578\u91cf\u3001ADS\u6578\u91cf\u3001\u6bcf\u80a1\u666e\u901a\u80a1\u548c\u6bcf\u80a1ADS\u6578\u64da\u5916\uff0c\u5176\u9918\u55ae\u4f4d\u5747\u70ba\u5343\u7f8e\u5143\uff09<\/p>\n<div>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u622a\u81f36\u670830\u65e5\u7684\u4e09\u500b\u6708<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u00a0<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u622a\u81f36\u670830\u65e5\u7684\u516d\u500b\u6708<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u00a0<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">2023\u5e74<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">2022\u5e741<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">2023\u5e74\u00a0<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">2022\u5e741<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\uff08\u672a\u7d93\u5be9\u8a08\uff09<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\uff08\u672a\u7d93\u5be9\u8a08\uff09<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u6536\u5165\uff1a<\/span><\/p>\n<p>     <\/p>\n<p class=\"prnml10\"><span class=\"prnews_span\">\u7522\u54c1\u6536\u5165\uff0c\u6de8\u984d<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">$\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 553,745<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">$\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 304,511<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">$\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 964,036<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">$\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 566,084<\/span><\/p>\n<p class=\"prnml10\"><span class=\"prnews_span\">\u5408\u4f5c\u6536\u5165<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">41,516<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">37,061<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">79,026<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">82,114<\/span><\/p>\n<p class=\"prnml20\"><span class=\"prnews_span\">\u7e3d\u6536\u5165<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">595,261<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">341,572<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">1,043,062<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">648,198<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u8cbb\u7528\uff1a<\/span><\/p>\n<p>     <\/p>\n<p class=\"prnml10\"><span class=\"prnews_span\">\u7522\u54c1\u92b7\u552e\u6210\u672c<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">95,990<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">71,173<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">177,779<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">136,410<\/span><\/p>\n<p class=\"prnml10\"><span class=\"prnews_span\">\u7814\u767c\u8cbb\u7528<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">422,764<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">378,207<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">831,348<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">768,122<\/span><\/p>\n<p class=\"prnml10\"><span class=\"prnews_span\">\u92b7\u552e\u53ca\u7ba1\u7406\u8cbb\u7528<\/span><span class=\"prnews_span\"> <\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">395,034<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">331,403<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">723,533<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">625,976<\/span><\/p>\n<p class=\"prnml10\"><span class=\"prnews_span\">\u7121\u5f62\u8cc7\u7522\u6524\u92b7<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">188<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">188<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">375<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">376<\/span><\/p>\n<p class=\"prnml20\"><span class=\"prnews_span\">\u7e3d\u8cbb\u7528<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">913,976<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">780,971<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">1,733,035<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">1,530,884<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u7d93\u71df\u8667\u640d<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">(318,715)<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">(439,399)<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">(689,973)<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">(882,686)<\/span><\/p>\n<p class=\"prnml10\"><span class=\"prnews_span\">\u5229\u606f\u6536\u5165\uff0c\u6de8\u984d<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">15,070<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">11,431<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">31,086<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">21,502<\/span><\/p>\n<p class=\"prnml10\"><span class=\"prnews_span\">\u5176\u4ed6\u8cbb\u7528\uff0c\u6de8\u984d<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">(63,818)<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">(129,617)<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">(45,515)<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">(117,650)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u6240\u5f97\u7a05\u524d\u8667\u640d<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">(367,463)<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">(557,585)<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">(704,402)<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">(978,834)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u6240\u5f97\u7a05\u8cbb\u7528<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">13,674<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">8,141<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">25,166<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">22,090<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u6de8\u8667\u640d<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">(381,137)<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">(565,726)<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">(729,568)<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">(1,000,924)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u6b78\u5c6c\u767e\u6fdf\u795e\u5dde\u7684\u6bcf\u80a1\u6de8\u8667\u640d\uff1a<\/span><\/p>\n<p>     <\/p>\n<p class=\"prnml10\"><span class=\"prnews_span\">\u57fa\u672c\u53ca\u7a00\u91cb<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">$\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 (0.28)<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">$\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 (0.42)<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">$\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 (0.54)<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">$\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 (0.75)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u6d41\u901a\u80a1\u52a0\u6b0a\u5e73\u5747\u6578\uff1a<\/span><\/p>\n<p>     <\/p>\n<p class=\"prnml10\"><span class=\"prnews_span\">\u57fa\u672c\u53ca\u7a00\u91cb<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">1,360,224,377<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">1,336,463,026<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">1,357,211,308<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">1,334,252,648<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u6b78\u5c6c\u767e\u6fdf\u795e\u5dde\u7684\u6bcf\u80a1<\/span><span class=\"prnews_span\">ADS<\/span><span class=\"prnews_span\">\u6de8\u8667\u640d\uff1a<\/span><\/p>\n<p>     <\/p>\n<p class=\"prnml10\"><span class=\"prnews_span\">\u57fa\u672c\u53ca\u7a00\u91cb<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">$\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 (3.64)<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">$\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 (5.50)<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">$\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 (6.99)<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">$\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 (9.75)<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">\u6d41\u901a<\/span><span class=\"prnews_span\">ADS<\/span><span class=\"prnews_span\">\u52a0\u6b0a\u5e73\u5747\u6578\uff1a<\/span><\/p>\n<p>     <\/p>\n<p class=\"prnml10\"><span class=\"prnews_span\">\u57fa\u672c\u53ca\u7a00\u91cb<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">104,632,644<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">102,804,848<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">104,400,870<\/span><\/p>\n<p>      <\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">102,634,819<\/span><\/p>\n<\/div>\n<p>1\u516c\u53f8\u4fee\u8a02\u4e86\u90e8\u5206\u524d\u671f\u8ca1\u52d9\u5831\u8868\u4ee5\u66f4\u6b63\u905e\u5ef6\u6240\u5f97\u7a05\u6de8\u8cc7\u7522\u4f30\u503c\u7684\u4e00\u9805\u5dee\u932f\uff0c\u8a72\u9805\u5dee\u932f\u5c0d\u5148\u524d\u5df2\u767c\u4f48\u76842022\u5e74\u7b2c\u4e8c\u5b63\u5ea6\u8ca1\u52d9\u5831\u8868\u4e0d\u91cd\u5927\uff08\u8acb\u53c3\u95b1\u5411\u7f8e\u570b\u8b49\u5238\u4ea4\u6613\u59d4\u54e1\u6703\u63d0\u4ea4\u7684\u622a\u81f32023\u5e746\u670830\u65e5\u768410-Q\u8868\u683c\u5b63\u5ea6\u5831\u544a\u4e2d\u7c21\u660e\u5408\u4f75\u8ca1\u52d9\u5831\u8868\u7684\u76f8\u95dc\u9644\u6ce8\uff0c\u300c\u9644\u6ce81.\u696d\u52d9\u63cf\u8ff0\u3001\u5448\u5217\u57fa\u6e96\u53ca\u5408\u4f75\u539f\u5247\u548c\u91cd\u5927\u6703\u8a08\u653f\u7b56\u300d\u4ee5\u53ca\u300c\u9644\u6ce82.\u524d\u671f\u8ca1\u52d9\u5831\u8868\u4fee\u8a02\u300d\uff09\u3002<\/p>\n<p>\u95dc\u65bc\u767e\u6fdf\u795e\u5dde<\/p>\n<p>\u767e\u6fdf\u795e\u5dde\u662f\u4e00\u5bb6\u5168\u7403\u6027\u751f\u7269\u79d1\u6280\u516c\u53f8\uff0c\u5c08\u6ce8\u65bc\u70ba\u5168\u7403\u764c\u75c7\u60a3\u8005\u767c\u73fe\u548c\u958b\u767c\u5275\u65b0\u6297\u816b\u7624\u85e5\u7269\uff0c\u63d0\u9ad8\u85e5\u7269\u53ef\u53ca\u6027\u548c\u53ef\u8ca0\u64d4\u6027\u3002\u901a\u904e\u5f37\u5927\u7684\u81ea\u4e3b\u7814\u767c\u80fd\u529b\u548c\u5916\u90e8\u6230\u7565\u5408\u4f5c\uff0c\u6211\u5011\u4e0d\u65b7\u52a0\u901f\u958b\u767c\u591a\u5143\u3001\u5275\u65b0\u7684\u85e5\u7269\u7ba1\u7dda\u3002\u6211\u5011\u81f4\u529b\u65bc\u70ba\u5168\u7403\u66f4\u591a\u60a3\u8005\u5168\u9762\u6539\u5584\u85e5\u7269\u53ef\u53ca\u6027\u3002\u767e\u6fdf\u795e\u5dde\u5728\u5168\u7403\u4e94\u5927\u6d32\u6253\u9020\u4e86\u4e00\u652f\u8d85\u904e10,000\u4eba\u7684\u5718\u968a\uff0c\u4e26\u5728\u4e2d\u570b\u5317\u4eac\u3001\u7f8e\u570b\u9ebb\u7701\u528d\u6a4b\u548c\u745e\u58eb\u5df4\u585e\u723e\u8a2d\u7acb\u4e86\u4e3b\u8981\u8fa6\u4e8b\u8655\u3002\u6b32\u77ad\u89e3\u66f4\u591a\u4fe1\u606f\uff0c\u8acb\u8a2a\u554f<a href=\"http:\/\/www.beigene.com.cn\/\" target=\"_blank\" rel=\"noopener\">www.beigene.com.cn<\/a>\u3002<\/p>\n<p>\u524d\u77bb\u6027\u8072\u660e<\/p>\n<p>\u672c\u65b0\u805e\u7a3f\u5305\u542b\u6839\u64da\u300a1995\u5e74\u79c1\u4eba\u8b49\u5238\u8a34\u8a1f\u6539\u9769\u6cd5\u6848\u300b\uff08Private Securities Litigation Reform Act of 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