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  600mg BID\u5291\u91cf\u7d44 (RP2D\u63a8\u85a6\u5291\u91cf) \u5448\u73fe\u66f4\u512a\u7684\u7642\u6548\uff0c\u572830\u4f8b\u53ef\u8a55\u4f30\u53d7\u8a66\u8005\u4e2d\uff0c ORR\u70ba66.7%(20\/30)\uff0c\u5176\u4e2d\u78ba\u8a8d\u7684\u5ba2\u89c0\u7de9\u89e3\u7387\uff08cORR\uff09\u70ba53.3%\uff0816\/30\uff09\u3002DCR\u70ba96.7%\u3002mDOR\u5c1a\u672a\u9054\u5230\uff0c6\u500b\u6708DOR\u7387\u70ba74.5%\uff0895% CI, 39.8-91.7\uff09\u3002mPFS\u70ba8.2\u500b\u6708\uff0cPFS\u4e8b\u4ef6\u6578\u70ba46.7%\uff0814\/30\uff09\uff0c6\u500b\u6708\u548c9\u500b\u6708\u7121\u9032\u5c55\u751f\u5b58\u7387\u5206\u5225\u70ba58.9%\uff0895% CI, 39.0-74.3\uff09\u548c47.3%\uff0895% CI, 26.1-65.8\uff09\uff0c\u4e2d\u4f4d\u96a8\u8a2a\u6642\u95938.1\u500b\u6708\uff0c\u6578\u64da\u5c1a\u672a\u6210\u719f\u3002   \u5b89\u5168\u6027\u65b9\u9762\uff0c\u622a\u81f32022\u5e7411\u670830\u65e5\uff0c\u7e3d\u9ad4\u8010\u53d7\u6027\u826f\u597d, 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