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class=\"prntaj\">\u672c\u65b0\u805e\u7a3f\u6240\u767c\u4f48\u7684\u4fe1\u606f\u4e2d\u53ef\u80fd\u6703\u5305\u542b\u67d0\u4e9b\u524d\u77bb\u6027\u8868\u8ff0\u3002\u9019\u4e9b\u8868\u8ff0\u672c\u8cea\u4e0a\u5177\u6709\u76f8\u7576\u98a8\u96aa\u548c\u4e0d\u78ba\u5b9a\u6027\u3002\u5728\u4f7f\u7528\u300c\u9810\u671f\u300d\u3001\u300c\u76f8\u4fe1\u300d\u3001\u300c\u9810\u6e2c\u300d\u3001\u300c\u671f\u671b\u300d\u3001\u300c\u6253\u7b97\u300d\u53ca\u5176\u4ed6\u985e\u4f3c\u8a5e\u8a9e\u9032\u884c\u8868\u8ff0\u6642\uff0c\u51e1\u8207\u672c\u516c\u53f8\u6709\u95dc\u7684\uff0c\u76ee\u7684\u5747\u662f\u8981\u6307\u660e\u5176\u5c6c\u524d\u77bb\u6027\u8868\u8ff0\u3002\u672c\u516c\u53f8\u4e26\u7121\u7fa9\u52d9\u4e0d\u65b7\u5730\u66f4\u65b0\u9019\u4e9b\u9810\u6e2c\u6027\u9673\u8ff0\u3002<\/p>\n<p class=\"prntaj\">\u9019\u4e9b\u524d\u77bb\u6027\u8868\u8ff0\u4e43\u57fa\u65bc\u672c\u516c\u53f8\u7ba1\u7406\u5c64\u5728\u505a\u51fa\u8868\u8ff0\u6642\u5c0d\u672a\u4f86\u4e8b\u52d9\u7684\u73fe\u6709\u770b\u6cd5\u3001\u5047\u8a2d\u3001\u671f\u671b\u3001\u4f30\u8a08\u3001\u9810\u6e2c\u548c\u7406\u89e3\u3002\u9019\u4e9b\u8868\u8ff0\u4e26\u975e\u5c0d\u672a\u4f86\u767c\u5c55\u7684\u4fdd\u8b49\uff0c\u6703\u53d7\u5230\u98a8\u96aa\u3001\u4e0d\u78ba\u6027\u53ca\u5176\u4ed6\u56e0\u7d20\u7684\u5f71\u97ff\uff0c\u6709\u4e9b\u4e43\u8d85\u51fa\u672c\u516c\u53f8\u7684\u63a7\u5236\u7bc4\u570d\uff0c\u96e3\u4ee5\u9810\u8a08\u3002\u56e0\u6b64\uff0c\u53d7\u6211\u5011\u7684\u696d\u52d9\u3001\u7af6\u722d\u74b0\u5883\u3001\u653f\u6cbb\u3001\u7d93\u6fdf\u3001\u6cd5\u5f8b\u548c\u793e\u6703\u60c5\u6cc1\u7684\u672a\u4f86\u8b8a\u5316\u53ca\u767c\u5c55\u7684\u5f71\u97ff\uff0c\u5be6\u969b\u7d50\u679c\u53ef\u80fd\u6703\u8207\u524d\u77bb\u6027\u8868\u8ff0\u6240\u542b\u8cc7\u6599\u6709\u8f03\u5927\u5dee\u5225\u3002<\/p>\n<p class=\"prntaj\">\u672c\u516c\u53f8\u3001\u672c\u516c\u53f8\u8463\u4e8b\u53ca\u50f1\u54e1\u4ee3\u7406\u6982\u4e0d\u627f\u64d4 (a) \u66f4\u6b63\u6216\u66f4\u65b0\u672c\u7db2\u7ad9\u6240\u8f09\u524d\u77bb\u6027\u8868\u8ff0\u7684\u4efb\u4f55\u7fa9\u52d9;\u53ca (b) \u82e5\u56e0\u4efb\u4f55\u524d\u77bb\u6027\u8868\u8ff0\u4e0d\u80fd\u5be6\u73fe\u6216\u8b8a\u6210\u4e0d\u6b63\u78ba\u800c\u5f15\u81f4\u7684\u4efb\u4f55\u8cac\u4efb\u3002<\/p>","protected":false},"excerpt":{"rendered":"<p>\u7f8e\u570b\u820a\u91d1\u5c71\u548c\u4e2d\u570b\u8607\u5dde2025\u5e741\u67082\u65e5 \/\u7f8e\u901a\u793e\/ &#8212; \u4fe1\u9054\u751f\u7269\u88fd\u85e5\u96c6\u5718\uff08\u9999\u6e2f\u806f\u4ea4\u6240\u80a1\u7968\u4ee3\u78bc\uff1a01801\uff09\uff08\u4ee5\u4e0b\u7c21\u7a31\u300c\u4fe1\u9054\u751f\u7269\u300d\uff09\uff0c\u4e00\u5bb6\u81f4\u529b\u65bc\u7814\u767c\u3001\u751f\u7522\u548c\u92b7\u552e\u816b\u7624\u3001\u81ea\u8eab\u514d\u75ab\u3001\u5fc3\u8840\u7ba1\u53ca\u4ee3\u8b1d\u3001\u773c\u79d1\u7b49\u91cd\u5927\u75be\u75c5\u9818\u57df\u5275\u65b0\u85e5\u7269\u7684\u751f\u7269\u88fd\u85e5\u516c\u53f8\uff0c\u4eca\u65e5\u5ba3\u4f48\u8207\u7f85\u6c0f\uff08SIX: RO, ROG; OTCQX: RHHBY\uff09\u9054\u6210\u5168\u7403\u7368\u5bb6\u5408\u4f5c\u8207\u8a31\u53ef\u5354\u8b70\uff0c\u4ee5\u63a8\u9032IBI3009\uff0c\u4e00\u6b3e\u9776\u5411Delta\u6a23\u914d\u9ad43\uff08DLL3\uff09\u7684\u65b0\u4e00\u4ee3\u6297\u9ad4\u5076\u806f\u85e5\u7269\uff08ADC\uff09\u5019\u9078\u7522\u54c1\u7684\u958b\u767c\uff0c\u65e8\u5728\u70ba\u665a\u671f\u5c0f\u7d30\u80de\u80ba\u764c\uff08SCLC\uff09\u60a3\u8005\u63d0\u4f9b\u5168\u65b0\u7684\u6cbb\u7642\u9078\u64c7\u3002IBI3009\u5df2\u5728\u6fb3\u5927\u5229\u4e9e\u3001\u4e2d\u570b\u548c\u7f8e\u570b\u7372\u5f97\u81e8\u5e8a\u7533\u8acb\uff08IND\uff09\u6279\u51c6\uff0c\u4e26\u65bc2024\u5e7412\u6708\u5b8c\u6210I\u671f\u81e8\u5e8a\u7814\u7a76\u9996\u4f8b\u60a3\u8005\u7d66\u85e5\u3002 IBI3009\uff1a\u6f5b\u5728\u540c\u985e\u6700\u4f73\u7684DLL3 ADC \u5019\u9078\u85e5\u7269 IBI3009\u7279\u7570\u6027\u9776\u5411DLL3\uff0c\u4e00\u7a2e\u5728\u6b63\u5e38\u7d44\u7e54\u4e2d\u4f4e\u8868\u9054\u3001\u4f46\u5728\u7279\u5b9a\u764c\u7a2e\u5c24\u5176\u662fSCLC\u548c\u5176\u4ed6\u795e\u7d93\u5167\u5206\u6ccc\u816b\u7624\u4e2d\u986f\u8457\u904e\u5ea6\u8868\u9054\u7684\u6297\u539f\u3002\u4f5c\u70ba\u6f5b\u5728\u540c\u985e\u6700\u4f73\u548c\u958b\u767c\u9032\u5ea6\u9818\u5148\u7684\u9776\u5411DLL3 ADC\u4e4b\u4e00\uff0cIBI3009\u57fa\u65bc\u4fe1\u9054\u751f\u7269\u5c08\u6709\u7684\u65b0\u578b\u62d3\u64b2\u7570\u69cb\u9176I\u6291\u5236\u5291\uff08TOPO1i\uff09\u5e73\u53f0\u8a2d\u8a08\u958b\u767c\u3002IBI3009\u5728\u591a\u500b\u816b\u7624\u8ca0\u8377\u5c0f\u9f20\u6a21\u578b\uff08\u5c24\u5176\u5728\u5316\u7642\u8010\u85e5\u816b\u7624\u985e\u578b\uff09\u4e2d\u5c55\u73fe\u51fa\u4e86\u4ee4\u4eba\u9f13\u821e\u7684\u6297\u816b\u7624\u6d3b\u6027\uff0c\u4e26\u5177\u6709\u826f\u597d\u7684\u5b89\u5168\u6027\u7279\u5fb5\u3002 \u4fe1\u9054\u751f\u7269\u9996\u5e2d\u5546\u52d9\u5b98\u5f35\u8607\u83ef\u535a\u58eb\u8868\u793a\uff1a\u300c\u6211\u5011\u5f88\u9ad8\u8208\u80fd\u5920\u518d\u6b21\u8207\u5168\u7403\u816b\u7624\u88fd\u85e5\u9818\u5c0e\u8005\u7f85\u6c0f\u9054\u6210\u6230\u7565\u5408\u4f5c\uff0c\u4ee5\u63a8\u9032\u6211\u5011\u6f5b\u5728\u540c\u985e\u6700\u4f73\u7684DLL3 ADC\u5019\u9078\u85e5\u7269\u7684\u958b\u767c\u3002\u6211\u5011\u671f\u5f85\u901a\u904e\u7d50\u5408\u4fe1\u9054\u751f\u7269\u7684\u5275\u65b0\u6280\u8853\u8207\u7f85\u6c0f\u7684\u79d1\u5b78\u6d1e\u898b\u548c\u5168\u7403\u7814\u767c\u5be6\u529b\uff0c\u5171\u540c\u63a8\u9032\u9ad8\u8cea\u91cf\u5275\u65b0\u85e5\u7269\u7684\u53ef\u53ca\u6027\uff0c\u8b93\u66f4\u591a\u7684\u5168\u7403\u60a3\u8005\u76e1\u65e9\u53d7\u76ca\u3002\u300d \u7f85\u6c0f\u96c6\u5718\u5168\u7403\u4f01\u696d\u696d\u52d9\u767c\u5c55\u8ca0\u8cac\u4ebaBoris L. 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