{"id":22799,"date":"2024-10-30T02:28:00","date_gmt":"2024-10-29T18:28:00","guid":{"rendered":"https:\/\/www.franchise.com.hk\/gemvax%e5%9c%a8neuro2024%e5%a4%a7%e6%9c%83%e4%b8%8a%e7%99%bc%e4%bd%88%e9%80%b2%e8%a1%8c%e6%80%a7%e6%a0%b8%e4%b8%8a%e6%80%a7%e9%ba%bb%e7%97%ba2a%e6%9c%9f%e8%87%a8%e5%ba%8a%e8%a9%a6%e9%a9%97%e9%a0%82\/22799"},"modified":"2024-10-30T02:28:00","modified_gmt":"2024-10-29T18:28:00","slug":"gemvax%e5%9c%a8neuro2024%e5%a4%a7%e6%9c%83%e4%b8%8a%e7%99%bc%e4%bd%88%e9%80%b2%e8%a1%8c%e6%80%a7%e6%a0%b8%e4%b8%8a%e6%80%a7%e9%ba%bb%e7%97%ba2a%e6%9c%9f%e8%87%a8%e5%ba%8a%e8%a9%a6%e9%a9%97%e9%a0%82","status":"publish","type":"post","link":"https:\/\/www.franchise.com.hk\/en\/gemvax%e5%9c%a8neuro2024%e5%a4%a7%e6%9c%83%e4%b8%8a%e7%99%bc%e4%bd%88%e9%80%b2%e8%a1%8c%e6%80%a7%e6%a0%b8%e4%b8%8a%e6%80%a7%e9%ba%bb%e7%97%ba2a%e6%9c%9f%e8%87%a8%e5%ba%8a%e8%a9%a6%e9%a9%97%e9%a0%82\/22799","title":{"rendered":"GemVax\u5728Neuro2024\u5927\u6703\u4e0a\u767c\u4f48\u9032\u884c\u6027\u6838\u4e0a\u6027\u9ebb\u75fa2a\u671f\u81e8\u5e8a\u8a66\u9a57\u9802\u7dda\u7d50\u679c"},"content":{"rendered":"

\u2014\u2014\u9802\u7dda\u6578\u64da\u652f\u6301\u9032\u51653\u671f\u8a66\u9a57\uff0c\u4e14\u986f\u793aGV1001\u6709\u671b\u6210\u70ba\u5168\u7403\u9996\u6b3ePSP\u6cbb\u7642\u85e5\u7269<\/p>\n

\u97d3\u570b\u9996\u723e<\/span>2024\u5e7410\u670830\u65e5<\/span> \/\u7f8e\u901a\u793e\/ — \u7576\u5730\u6642\u959310\u670824\u65e5\u4e0b\u53484\u9ede45\u5206\uff0cGemVax & KAEL Co., Ltd.\uff08\u7c21\u7a31\u300cGemVax\u300d\uff1bKOSDAQ\u80a1\u7968\u4ee3\u78bc\uff1a082270\uff09\u5728\u52a0\u62ff\u5927\u591a\u502b\u591a\u8209\u8fa6\u7684\u300cNeuro2024\uff1aPSP\u548cCBD\u570b\u969b\u7814\u7a76\u7814\u8a0e\u6703\u300d\u4e0a\u516c\u4f48\u4e86\u5176\u6cbb\u7642\u9032\u884c\u6027\u6838\u4e0a\u6027\u9ebb\u75fa(PSP)\u7684\u7814\u7a76\u7528\u591a\u80bd\u85e5\u7269GV1001\u76842a\u671f\u81e8\u5e8a\u8a66\u9a57\uff08\u7c21\u7a31\u300c2a\u671fPSP\u81e8\u5e8a\u8a66\u9a57\u300d\uff09\u7684\u9802\u7dda\u7d50\u679c\u3002<\/p>\n

PSP\u662f\u4e00\u7a2e\u9000\u884c\u6027\u75be\u75c5\uff0c\u8207\u5e15\u91d1\u68ee\u75c5\u4e00\u6a23\uff0c\u4e5f\u6703\u5c0e\u81f4\u6b65\u614b\u969c\u7919\u3001\u65e9\u671f\u8dcc\u5012\u3001\u5782\u76f4\u6027\u51dd\u8996\u9ebb\u75fa\u3001\u50f5\u76f4\u3001\u9707\u986b\u548c\u8a8d\u77e5\u80fd\u529b\u4e0b\u964d\u7b49\u75c7\u72c0\uff0c\u4f46\u5176\u75c5\u7a0b\u9032\u5c55\u66f4\u5feb\uff0c\u76ee\u524d\u5c1a\u7121\u6839\u6cbb\u624b\u6bb5\u3002PSP\u5206\u70ba\u591a\u7a2e\u985e\u578b\uff0c\u5305\u62ecPSP-\u7406\u67e5\u68ee\u7d9c\u5408\u5f81(PSP-RS)\u548cPSP-\u5e15\u91d1\u68ee\u7d9c\u5408\u5f81(PSP-P)\u3002\u76f8\u8f03\u65bc\u5176\u4ed6\u985e\u578b\uff0cPSP-RS\u578b\u8868\u73fe\u51fa\u66f4\u70ba\u986f\u8457\u7684tau\u86cb\u767d\u805a\u96c6\uff0c\u4e14\u5f71\u97ff\u7bc4\u570d\u66f4\u5ee3\uff0c\u6d89\u53ca\u5c0f\u8166\u3001\u9f52\u72c0\u6838\u3001\u6a4b\u8166\u6838\u3001\u984d\u8449\u53ca\u9802\u8449\u7b49\u5340\u57df\u3002<\/p>\n

2a\u671fPSP\u81e8\u5e8a\u8a66\u9a57\u662f\u4e00\u9805\u70ba\u671f24\u5468\u7684\u96a8\u6a5f\u3001\u96d9\u76f2\u3001\u5b89\u6170\u5291\u5c0d\u7167\u524d\u77bb\u6027\u63a2\u7d22\u6027\u81e8\u5e8a\u8a66\u9a57\uff0c\u5728\u97d3\u570b5\u500b\u7814\u7a76\u4e2d\u5fc3\u5171\u62db\u52df\u4e8678\u540dPSP\u60a3\u8005\u3002\u53c3\u8207\u8005\u63091:1:1\u7684\u6bd4\u4f8b\u96a8\u6a5f\u5206\u914d\uff0c\u5206\u5225\u63a5\u53d7\u5b89\u6170\u5291\u30010.56\u6beb\u514bGV1001\u62161.12\u6beb\u514bGV1001\u6cbb\u7642\u3002\u6cbb\u7642\u65b9\u6848\u70ba\u524d4\u5468\uff081\u500b\u6708\uff09\u6bcf\u9031\u4e00\u6b21\u76ae\u4e0b\u6ce8\u5c04\uff0c\u96a8\u5f8c\u6bcf2\u5468\u6ce8\u5c04\u4e00\u6b21\uff0c\u6301\u7e8c20\u5468\uff085\u500b\u6708\uff09\uff0c\u7e3d\u5171\u70ba\u671f24\u5468\uff086\u500b\u6708\uff09\u3002\u8a72\u8a66\u9a57\u9762\u5411PSP-RS\u548cPSP-P\u5169\u7a2e\u985e\u578b\u7684\u60a3\u8005\u958b\u653e\u3002\u8a66\u9a57\u7d50\u679c\u986f\u793a\uff0c\u4f4e\u5291\u91cf\u7d44\uff080.56\u6beb\u514b\uff09\u7642\u6548\u66f4\u70ba\u986f\u8457\uff0c\u5c24\u5176\u5c0dPSP-RS\u578b\u60a3\u8005\u6548\u679c\u66f4\u4f73\u3002<\/p>\n

\u8a66\u9a57\u7684\u4e3b\u8981\u7d42\u9ede\u662f\u4f7f\u7528GV1001\u6cbb\u764224\u5468\u5f8cPSP\u8a55\u4efd\u91cf\u8868\u7e3d\u5206\uff08\u63a1\u7528MMRM\u6cd5\u8a08\u7b97\u7684\u6700\u5c0f\u4e8c\u4e58\u5747\u6578\uff09\u8f03\u57fa\u7dda\u7684\u8b8a\u5316\u3002\u7d50\u679c\u986f\u793a\uff0c0.56\u6beb\u514b\u5291\u91cf\u7d44\u75c5\u60c5\u60e1\u53162.14\u5206\uff0c\u800c\u5b89\u6170\u5291\u7d444.10\u5206\uff0c\u8aaa\u660e\u75be\u75c5\u9032\u7a0b\u6e1b\u7de9\u4e8648%\uff08\u898b\u57161\uff09\u3002\u5118\u7ba1\u672a\u9054\u7d71\u8a08\u5b78\u986f\u8457\u5dee\u7570\uff0c\u4f46\u9019\u4e9b\u767c\u73fe\u4ecd\u63ed\u793a\u4e86GV1001\u6cbb\u7642\u76ee\u524d\u7121\u6cd5\u6cbb\u7652\u7684PSP\u7684\u6f5b\u529b\uff0c\u4e26\u70ba\u63a8\u9032GV1001\u81f3\u66f4\u9ad8\u7d1a\u5225\u81e8\u5e8a\u8a66\u9a57\u63d0\u4f9b\u4e86\u4f9d\u64da\u3002<\/p>\n

\n

<\/a>
Figure 1. PSP-Rating Scale Total Score (PSP-RS Type + PSP-P Type_ LS mean using MMRM)<\/span><\/p>\n<\/div>\n

\u81e8\u5e8a\u4e0a\uff0c\u591a\u6578PSP\u60a3\u8005\u5c6c\u65bc\u5178\u578b\u7684PSP-RS\u578b\uff0c\u9019\u4e00\u985e\u578b\u8f03\u5176\u4ed6PSP\u985e\u578b\u75c5\u7a0b\u9032\u5c55\u66f4\u5feb\uff0c\u5e73\u5747\u751f\u5b58\u671f\u4e5f\u66f4\u77ed\u3002\u8a66\u9a57\u5c08\u9580\u91dd\u5c0dPSP-RS\u578b\u60a3\u8005\u9032\u884c\u4e86\u5206\u7d44\u5206\u6790\u3002\u5728\u670d\u7528GV1001\u4e8c\u5341\u56db\u5468\u5f8c\uff0c\u63a1\u7528\u7c21\u55ae\u5e73\u5747\u6cd5\u8a08\u7b97PSP\u8a55\u4efd\u91cf\u8868\u7e3d\u5206\u5747\u503c\u7684\u8b8a\u5316\uff0c\u7d50\u679c\u986f\u793a\uff0c0.56\u6beb\u514b\u5291\u91cf\u7d44\u75c5\u60c5\u60e1\u5316\u5e73\u5747\u5206\u70ba0.25\u5206\uff0c\u800c\u5b89\u6170\u5291\u7d44\u70ba5.19\u5206\uff0c\u5169\u7d44\u76f8\u5dee4.94\u5206\uff0c\u8aaa\u660e\u75be\u75c5\u60e1\u5316\u7a0b\u5ea6\u964d\u4f4e\u4e8695%\uff08\u898b\u57162\uff09\u3002<\/p>\n

\n

<\/a>
Figure 2. PSP-Rating Scale Total Score (PSP-RS Type_ simple average)<\/span><\/p>\n<\/div>\n

\u6cbb\u7642\u7d44\u4e2d\u591a\u6578PSP-RS\u578b\u60a3\u8005\u5728\u8a66\u9a57\u671f\u9593\u75c7\u72c0\u4fdd\u6301\u7a69\u5b9a\u751a\u81f3\u6709\u6240\u6539\u5584\u3002\u4ee5\u6cbb\u76426\u500b\u6708\u5f8cPSP\u8a55\u4efd\u91cf\u8868\u7e3d\u5206\u8207\u57fa\u7dda\u76f8\u6bd4\u6709\u6240\u6539\u5584\u6216\u4fdd\u6301\u7a69\u5b9a\u7684\u60a3\u8005\u6bd4\u4f8b\u4f86\u8a08\u7b97\u7de9\u89e3\u7387\uff0c0.56\u6beb\u514bGV1001\u7d44\u670958.33%\u7684PSP-RS\u578b\u60a3\u8005\u75c7\u72c0\u5f97\u5230\u4e86\u6539\u5584\u6216\u7a69\u5b9a\uff08\u898b\u57163\uff09\u3002<\/p>\n

\n

<\/a>
Figure 3. Responder Rate (PSP-RS Type)<\/span><\/p>\n<\/div>\n

\u57282a\u671fPSP\u81e8\u5e8a\u8a66\u9a57\u4e2d\uff0cGV1001\u7684\u5b89\u5168\u6027\u8868\u73fe\u8207\u4e4b\u524d\u7684\u6578\u64da\u76f8\u7b26\uff0c\u6574\u9ad4\u8010\u53d7\u6027\u826f\u597d\uff0c\u672a\u89c0\u5bdf\u5230\u8207\u85e5\u7269\u76f8\u95dc\u7684\u56b4\u91cd\u4e0d\u826f\u4e8b\u4ef6\u3002<\/p>\n

GemVax\u9996\u5e2d\u6230\u7565\u5b98Hyungsik Moon\u6307\u51fa\uff1a\u300c\u672c\u6b212a\u671f\u8a66\u9a57\u5c6c\u65bc\u63a2\u7d22\u6027\u7814\u7a76\uff0c\u65e8\u5728\u78ba\u5b9a\u6700\u512a\u5291\u91cf\u53ca\u591a\u80bd\u5c0d\u4e0d\u540c\u5206\u7d44\u7684\u6548\u679c\u3002\u5118\u7ba1\u9802\u7dda\u7d50\u679c\u672a\u9054\u5230\u7d71\u8a08\u5b78\u986f\u8457\u6027\uff0c\u4f46\u6240\u63d0\u4f9b\u7684\u8b49\u64da\u5df2\u5145\u5206\u652f\u6301\u6211\u5011\u8003\u616e\u63a8\u9032\u81f3\u95dc\u9375\u6027\u8a66\u9a57\uff0c\u540c\u6642\u8868\u660eGV1001\u6709\u671b\u6210\u70ba\u5168\u7403\u9996\u500bPSP\u6cbb\u7642\u65b9\u6848\u3002\u300d<\/p>\n

\u51fa\u5e2dNeuro2024\u6703\u8b70\u7684\u5c08\u5bb6\u5c0dPSP\u8a66\u9a57\u7d50\u679c\u8868\u793a\u6b61\u8fce\uff0c\u8a8d\u70ba\u6210\u679c\u632f\u596e\u4eba\u5fc3\uff0c\u4e26\u5c0d\u8a72\u85e5\u5373\u5c07\u9081\u5165\u5168\u74033\u671f\u81e8\u5e8a\u8a66\u9a57\u9032\u884c\u66f4\u6df1\u5165\u7684\u7814\u767c\u611f\u5230\u9ad8\u8208\u3002<\/p>\n

\u5168\u7403CRO ICON\u85e5\u7269\u958b\u767c\u9ad8\u7d1a\u526f\u7e3d\u88c1\u3001\u91ab\u5b78\u535a\u58ebPeter Sch\u00fcler<\/span>\u8868\u793a\uff1a\u300c\u9019\u9805\u8a66\u9a57\u6027\u7814\u7a76\u4e26\u975e\u5b8c\u5168\u6709\u6548\uff0c\u4e146\u500b\u6708\u7684\u6cbb\u7642\u9031\u671f\u76f8\u5c0d\u8f03\u77ed\uff0c\u56e0\u6b64\u7121\u6cd5\u9810\u671f\u7372\u5f97\u5177\u6709\u7d71\u8a08\u5b78\u610f\u7fa9\u7684\u78ba\u8b49\u7d50\u679c\u3002\u4e0d\u904e\uff0c\u5728\u904b\u52d5\u8868\u73fe\u548c\u8a8d\u77e5\u529f\u80fd\u9019\u5169\u500b\u9818\u57df\uff0c\u6211\u5011\u89c0\u5bdf\u5230\u7684\u8da8\u52e2\u65e2\u5408\u7406\u53c8\u4e00\u81f4\uff0c\u5747\u986f\u793a\u51fa\u4f4e\u5291\u91cf\u7d44\u7684\u512a\u52e2\u3002\u300d<\/p>\n

Sch\u00fcler<\/span>\u535a\u58eb\u8868\u793a\uff1a\u300c\u672c\u6b21\u8a66\u9a57\u78ba\u5b9a\u4e86\u6700\u4f73\u5291\u91cf\uff0c\u9019\u4e5f\u662f2a\u671f\u7814\u7a76\u7684\u4e3b\u8981\u76ee\u6a19\u4e4b\u4e00\uff0c\u4e26\u5c55\u73fe\u4e86\u8207\u5b89\u6170\u5291\u7d44\u76f8\u6bd4\uff0c\u75c5\u60c5\u5b8c\u5168\u7a69\u5b9a\u9019\u4e00\u5177\u6709\u81e8\u5e8a\u610f\u7fa9\u7684\u597d\u8655\u3002\u9019\u4e9b\u9802\u7dda\u6578\u64da\u70ba\u63a8\u9032\u81f33\u671f\u7814\u7a76\u63d0\u4f9b\u4e86\u6709\u529b\u7684\u4f9d\u64da\u3002\u300d<\/p>\n

\u6155\u5c3c\u9ed1\u5927\u5b78\u9644\u5c6c\u91ab\u9662(LMU Hospital)\u795e\u7d93\u79d1\u4e3b\u4efb\u3001\u5168\u7403\u77e5\u540dPSP\u5c08\u5bb6G\u00fcnter U. H\u00f6glinger<\/span>\u535a\u58eb\u8a55\u50f9\u9053\uff1a\u300c\u5728\u5168\u65b0\u4f5c\u7528\u6a5f\u5236\u7684\u65b0\u85e5\u7814\u7a76\u4e2d\uff0c\u6211\u5011\u7372\u5f97\u4e86\u6975\u70ba\u632f\u596e\u76842\u671f\u81e8\u5e8a\u6578\u64da\u3002\u5118\u7ba1\u6578\u64da\u5c1a\u5c6c\u521d\u6b65\uff0c\u4f46\u524d\u666f\u5ee3\u95ca\uff0c\u4e14\u8207[GV1001]\u5728\u963f\u723e\u8328\u6d77\u9ed8\u75c5\u4e2d\u7684\u81e8\u5e8a\u6578\u64da\u76f8\u5951\u5408\u3002\u6211\u5c0d\u63a5\u4e0b\u4f86\u7684\u7814\u767c\u5145\u6eff\u671f\u5f85\uff0c\u4e26\u5f88\u69ae\u5e78\u80fd\u53c3\u8207\u4e26\u9818\u5c0e[PSP]\u76843\u671f\u7814\u7a76\u3002\u300d<\/p>\n

CurePSP\u4e3b\u4efbKristophe Diaz\u535a\u58eb\u8868\u793a\uff1a\u300cGemVax\u6700\u8fd1\u7684\u81e8\u5e8a\u8a66\u9a57\u7d50\u679c\u4ee4\u4eba\u632f\u596e\uff0c\u70ba\u6574\u500bPSP\u7fa4\u9ad4\uff0c\u5305\u62ec\u76ee\u524d\u5c1a\u7121\u6cbb\u7642\u9078\u64c7\u7684\u60a3\u8005\u3001\u5bb6\u5c6c\u53ca\u6cbb\u7642\u4ed6\u5011\u7684\u91ab\u751f\uff0c\u5e36\u4f86\u4e86\u5e0c\u671b\u3002\u6211\u5011\u795d\u8cc0GemVax\u6210\u529f\u5b8c\u6210\u8a66\u9a57\uff0c\u4e26\u671f\u5f85\u5176\u80fd\u7e7c\u7e8c\u70baPSP\u793e\u7fa4\u5e36\u4f86\u66f4\u591a\u798f\u7949\u3002\u300d\u4ed6\u9084\u5f37\u8abf\uff1a\u300cCurePSP\u5c07\u4e00\u5982\u65e2\u5f80\u5730\u81f4\u529b\u65bc\u5408\u4f5c\uff0c\u652f\u6301\u70ba\u9019\u4e00\u6bc0\u6ec5\u6027\u75be\u75c5\u60a3\u8005\u5e36\u4f86\u5e0c\u671b\u8207\u6210\u679c\u7684\u5404\u9805\u5de5\u4f5c\u3002\u300d<\/p>\n

\u4e0b\u8f09PDF\uff1ahttps:\/\/mma.prnewswire.com\/media\/2542940\/2024_10_29__GemVax_Announces_Topline_Results.pdf<\/a><\/p>\n

\u95dc\u65bc2a\u671fPSP\u81e8\u5e8a\u8a66\u9a57(NCT05819658)<\/p>\n

2a\u671fPSP\u81e8\u5e8a\u8a66\u9a57\u662f\u4e00\u9805\u70ba\u671f24\u5468\u7684\u591a\u4e2d\u5fc3\u3001\u96a8\u6a5f\u3001\u96d9\u76f2\u3001\u5b89\u6170\u5291\u5c0d\u7167\u524d\u77bb\u6027\u63a2\u7d22\u6027\u81e8\u5e8a\u7814\u7a76\uff0c\u65e8\u5728\u8a55\u4f300.56\u6beb\u514b\u62161.12\u6beb\u514bGV1001\u8207\u5b89\u6170\u5291\u76f8\u6bd4\u5728\u6cbb\u7642PSP\u60a3\u8005\u4e0a\u7684\u5b89\u5168\u6027\u548c\u7642\u6548\u3002\u4e3b\u8981\u7d42\u9ede\u70ba\u4f7f\u7528GV1001\u6cbb\u764224\u5468\u5f8c\uff0cPSP\u8a55\u4efd\u91cf\u8868\u7e3d\u5206\u76f8\u5c0d\u65bc\u57fa\u7dda\u7684\u8b8a\u5316\u3002\u6b21\u8981\u7d42\u9ede\u5247\u5305\u62ec3\u500b\u6708\u6642PSP\u8a55\u4efd\u91cf\u8868\u7e3d\u5206\u4ee5\u53ca3\u500b\u6708\u548c6\u500b\u6708\u6642MoCA-K\u3001K-FAB\u548cES-ADL\u8a55\u5206\u76f8\u5c0d\u65bc\u57fa\u7dda\u7684\u8b8a\u5316\u3002\u6b64\u5916\uff0c\u7814\u7a76\u9084\u5168\u9762\u8a55\u4f30\u4e86GV1001\u7684\u7e3d\u9ad4\u5b89\u5168\u6027\u3002<\/p>\n

\u95dc\u65bcGV1001<\/p>\n

GV1001\u662f\u4e00\u7a2e\u5408\u6210\u80bd\uff0c\u753116\u500b\u6c28\u57fa\u9178\u69cb\u6210\uff0c\u4ee5\u7aef\u7c92\u9176\u7684\u95dc\u9375\u5e8f\u5217\u70ba\u57fa\u790e\u3002\u5b83\u5df2\u88ab\u7814\u7a76\u7528\u65bc\u6cbb\u7642\u5305\u62ec\u963f\u723e\u8328\u6d77\u9ed8\u75c5\u548cPSP\u5728\u5167\u7684\u795e\u7d93\u9000\u884c\u6027\u75be\u75c5\u3002\u7814\u7a76\u986f\u793a\uff0cGV1001\u80fd\u5920\u8abf\u7bc0\u795e\u7d93\u81a0\u8cea\u7d30\u80de\u7684\u8868\u578b\u4e26\u6e1b\u8f15\u795e\u7d93\u708e\u75c7\u3002\u9664\u4e86\u6b63\u5728\u9032\u884c\u76842a\u671fPSP\u81e8\u5e8a\u8a66\u9a57\u5916\uff0c\u91dd\u5c0d\u963f\u723e\u8328\u6d77\u9ed8\u75c5\u76842\u671f\u81e8\u5e8a\u8a66\u9a57\u4e5f\u6b63\u5728\u7f8e\u570b\u548c\u6b50\u6d32\u540c\u6b65\u63a8\u9032(NCT05189210)\u3002<\/p>\n

\u95dc\u65bcPSP<\/p>\n

\u9032\u884c\u6027\u6838\u4e0a\u6027\u9ebb\u75fa\u662f\u4e00\u7a2e\u7f55\u898b\u7684\u3001\u6210\u5e74\u5f8c\u767c\u75c5\u7684\u9032\u884c\u6027\u795e\u7d93\u9000\u884c\u6027\u75be\u75c5\uff0c\u76ee\u524d\u5c1a\u7121\u85e5\u7269\u80fd\u6539\u8b8a\u5176\u75c5\u7a0b\u3002\u5168\u7403\u767c\u75c5\u7387\u7d04\u70ba\u6bcf\u5341\u842c\u4eba\u4e2d\u6709\u4e03\u4f8b\uff0c\u4e14\u7537\u6027\u66f4\u70ba\u5e38\u898b\u3002\u60a3\u8005\u591a\u70ba60\u6b72\u4ee5\u4e0a\u7684\u8001\u5e74\u4eba\u3002PSP\u7684\u75c7\u72c0\u5305\u62ec\u5e73\u8861\u611f\u55aa\u5931\u3001\u6027\u683c\u8b8a\u5316\u3001\u773c\u7403\u6d3b\u52d5\u7121\u529b\uff08\u5c24\u5176\u662f\u5411\u4e0b\u770b\u6642\uff09\u3001\u541e\u56a5\u56f0\u96e3\u3001\u8a00\u8a9e\u4e0d\u6e05\u4ee5\u53ca\u8a8d\u77e5\u529f\u80fd\u53d7\u640d\u3002<\/p>\n

\u95dc\u65bcGemVax & KAEL<\/p>\n

GemVax & KAEL Co., Ltd.\u662f\u97d3\u570b\u4e00\u5bb6\u8655\u65bc\u81e8\u5e8a\u968e\u6bb5\u7684\u751f\u7269\u88fd\u85e5\u5148\u92d2\u4f01\u696d\uff0c\u5c08\u6ce8\u65bc\u7814\u767c\u6cbb\u7642\u795e\u7d93\u9000\u884c\u6027\u75be\u75c5\uff08\u5982\u9032\u884c\u6027\u6838\u4e0a\u6027\u9ebb\u75fa\u548c\u963f\u723e\u8328\u6d77\u9ed8\u75c5\uff09\u7684\u5c08\u5229\u7642\u6cd5\u3002\u91dd\u5c0dPSP\uff0cGemVax\u6b63\u5728\u97d3\u570b\u9032\u884c2a\u671f\u7814\u7a76\uff0c\u4ee5\u8a55\u4f30GV1001\u5c0dPSP\u60a3\u8005\u7684\u7642\u6548\u8207\u5b89\u5168\u6027\uff0c\u540c\u6642\u4e5f\u5728\u7c4c\u5099\u5168\u7403\u6027\u7684PSP\u81e8\u5e8a\u8a66\u9a57\u3002\u6b64\u5916\uff0c\u516c\u53f8\u76ee\u524d\u9084\u5728\u7f8e\u570b\u548c\u6b50\u6d32\u540c\u6b65\u958b\u5c55\u963f\u723e\u8328\u6d77\u9ed8\u75c5\u76842\u671f\u81e8\u5e8a\u8a66\u9a57\u3002\u6b32\u77ad\u89e3\u66f4\u591a\u4fe1\u606f\uff0c\u8acb\u8a2a\u554fwww.gemvax.com<\/a>\u4e26\u5728Linkedin<\/a>\u4e0a\u95dc\u6ce8\u6211\u5011\u3002<\/p>\n

\u524d\u77bb\u6027\u9673\u8ff0<\/p>\n

\u672c\u6587\u4ef6\u6240\u542b\u4fe1\u606f\u5305\u62ec\u6216\u57fa\u65bc\u300a1995\u5e74\u8b49\u5238\u8a34\u8a1f\u6539\u9769\u6cd5\u6848\u300b\u754c\u5b9a\u7684\u300c\u524d\u77bb\u6027\u9673\u8ff0\u300d\u3002\u9019\u4e9b\u9673\u8ff0\u53ef\u80fd\u4f7f\u7528\u300c\u8a08\u5283\u300d\u3001\u300c\u5c07\u8981\u300d\u3001\u300c\u9810\u8a08\u300d\u3001\u300c\u9810\u6e2c\u300d\u3001\u300c\u6253\u7b97\u300d\u3001\u300c\u76f8\u4fe1\u300d\u3001\u300c\u6f5b\u529b\u300d\u3001\u300c\u7e7c\u7e8c\u300d\u7b49\u660e\u78ba\u6a19\u8b58\u8a5e\uff0c\u6216\u5176\u4ed6\u985e\u4f3c\u8868\u8ff0\uff0c\u4e5f\u53ef\u80fd\u4e0d\u4f7f\u7528\u3002\u6b64\u985e\u9673\u8ff0\u53d7\u5df2\u77e5\u548c\u672a\u77e5\u98a8\u96aa\u53ca\u4e0d\u78ba\u5b9a\u6027\u7684\u5f71\u97ff\uff0c\u53ef\u80fd\u5c0e\u81f4\u5be6\u969b\u7d50\u679c\u8207\u9673\u8ff0\u4e2d\u660e\u793a\u6216\u6697\u793a\u7684\u7d50\u679c\u6709\u91cd\u5927\u51fa\u5165\u3002\u9019\u4e9b\u98a8\u96aa\u548c\u4e0d\u78ba\u5b9a\u6027\u5305\u62ec\u4f46\u4e0d\u9650\u65bc\uff1a\u85e5\u7269\u7814\u767c\u7684\u56fa\u6709\u6311\u6230\uff08\u5982\u81e8\u5e8a\u524d\u548c\u81e8\u5e8a\u9805\u76ee\u7684\u6642\u9593\u5b89\u6392\u548c\u7d50\u679c\uff0c\u9019\u4e9b\u9805\u76ee\u56e0\u9ad8\u98a8\u96aa\u800c\u53ef\u80fd\u5728\u4efb\u4f55\u968e\u6bb5\u5931\u6557\uff0c\u5305\u62ec\u76e3\u7ba1\u5be9\u6279\u524d\u5f8c\u56e0\u7642\u6548\u4e0d\u4f73\u3001\u5b89\u5168\u6027\u554f\u984c\u6216\u5176\u4ed6\u56e0\u7d20\u5c0e\u81f4\u7684\u5931\u6557\uff09\uff1b\u6211\u5011\u5229\u7528\u548c\u52a0\u5f37\u85e5\u7269\u767c\u73fe\u5e73\u53f0\u7684\u80fd\u529b\uff1b\u6211\u5011\u70ba\u958b\u767c\u6d3b\u52d5\u548c\u5176\u4ed6\u4f01\u696d\u76ee\u7684\u7c4c\u96c6\u8cc7\u91d1\u7684\u80fd\u529b\uff1b\u6211\u5011\u5408\u4f5c\u9805\u76ee\u7684\u6210\u6557\uff1b\u6211\u5011\u7372\u5f97\u76e3\u7ba1\u6279\u51c6\u4e26\u6700\u7d42\u5be6\u73fe\u85e5\u7269\u5019\u9078\u7522\u54c1\u5546\u696d\u5316\u7684\u80fd\u529b\uff1b\u6211\u5011\u7372\u53d6\u3001\u7dad\u6301\u548c\u843d\u5be6\u77e5\u8b58\u7522\u6b0a\u4fdd\u8b77\u7684\u80fd\u529b\uff1b\u6211\u5011\u7684\u6280\u8853\u7cfb\u7d71\u906d\u53d7\u7db2\u7d61\u653b\u64ca\u6216\u5176\u4ed6\u5e72\u64fe\u7684\u98a8\u96aa\uff1b\u6211\u5011\u5438\u5f15\u3001\u6fc0\u52f5\u548c\u7559\u4f4f\u95dc\u9375\u4eba\u624d\u4ee5\u53ca\u7ba1\u7406\u589e\u9577\u7684\u80fd\u529b\uff1b\u901a\u8ca8\u81a8\u8139\u548c\u5176\u4ed6\u5b8f\u89c0\u7d93\u6fdf\u554f\u984c\uff1b\u4ee5\u53ca\u5176\u4ed6\u98a8\u96aa\u548c\u4e0d\u78ba\u5b9a\u6027\u3002\u6240\u6709\u524d\u77bb\u6027\u9673\u8ff0\u5747\u57fa\u65bc\u7ba1\u7406\u5c64\u7576\u524d\u7684\u4f30\u8a08\u3001\u9810\u6e2c\u548c\u5047\u8a2d\uff0c\u9664\u975e\u6cd5\u5f8b\u53e6\u6709\u8981\u6c42\uff0cGemVax\u4e0d\u627f\u64d4\u66f4\u6b63\u6216\u66f4\u65b0\u9019\u4e9b\u9673\u8ff0\u7684\u7fa9\u52d9\uff0c\u7121\u8ad6\u662f\u56e0\u70ba\u65b0\u4fe1\u606f\u7684\u51fa\u73fe\u3001\u672a\u4f86\u4e8b\u614b\u7684\u767c\u5c55\u9084\u662f\u5176\u4ed6\u539f\u56e0\u3002<\/p>\n

\n

<\/a>
<\/span><\/p>\n<\/div>\n

\u00a0<\/p>\n

\n<\/div>","protected":false},"excerpt":{"rendered":"

\u2014\u2014\u9802\u7dda\u6578\u64da\u652f\u6301\u9032\u51653\u671f\u8a66\u9a57\uff0c\u4e14\u986f\u793aGV1001\u6709\u671b\u6210\u70ba\u5168\u7403\u9996\u6b3ePSP\u6cbb\u7642\u85e5\u7269 \u97d3\u570b\u9996\u723e2024\u5e7410\u670830\u65e5 \/\u7f8e\u901a\u793e\/ — \u7576\u5730\u6642\u959310\u670824\u65e5\u4e0b\u53484\u9ede45\u5206\uff0cGemVax & KAEL Co., Ltd.\uff08\u7c21\u7a31\u300cGemVax\u300d\uff1bKOSDAQ\u80a1\u7968\u4ee3\u78bc\uff1a082270\uff09\u5728\u52a0\u62ff\u5927\u591a\u502b\u591a\u8209\u8fa6\u7684\u300cNeuro2024\uff1aPSP\u548cCBD\u570b\u969b\u7814\u7a76\u7814\u8a0e\u6703\u300d\u4e0a\u516c\u4f48\u4e86\u5176\u6cbb\u7642\u9032\u884c\u6027\u6838\u4e0a\u6027\u9ebb\u75fa(PSP)\u7684\u7814\u7a76\u7528\u591a\u80bd\u85e5\u7269GV1001\u76842a\u671f\u81e8\u5e8a\u8a66\u9a57\uff08\u7c21\u7a31\u300c2a\u671fPSP\u81e8\u5e8a\u8a66\u9a57\u300d\uff09\u7684\u9802\u7dda\u7d50\u679c\u3002 PSP\u662f\u4e00\u7a2e\u9000\u884c\u6027\u75be\u75c5\uff0c\u8207\u5e15\u91d1\u68ee\u75c5\u4e00\u6a23\uff0c\u4e5f\u6703\u5c0e\u81f4\u6b65\u614b\u969c\u7919\u3001\u65e9\u671f\u8dcc\u5012\u3001\u5782\u76f4\u6027\u51dd\u8996\u9ebb\u75fa\u3001\u50f5\u76f4\u3001\u9707\u986b\u548c\u8a8d\u77e5\u80fd\u529b\u4e0b\u964d\u7b49\u75c7\u72c0\uff0c\u4f46\u5176\u75c5\u7a0b\u9032\u5c55\u66f4\u5feb\uff0c\u76ee\u524d\u5c1a\u7121\u6839\u6cbb\u624b\u6bb5\u3002PSP\u5206\u70ba\u591a\u7a2e\u985e\u578b\uff0c\u5305\u62ecPSP-\u7406\u67e5\u68ee\u7d9c\u5408\u5f81(PSP-RS)\u548cPSP-\u5e15\u91d1\u68ee\u7d9c\u5408\u5f81(PSP-P)\u3002\u76f8\u8f03\u65bc\u5176\u4ed6\u985e\u578b\uff0cPSP-RS\u578b\u8868\u73fe\u51fa\u66f4\u70ba\u986f\u8457\u7684tau\u86cb\u767d\u805a\u96c6\uff0c\u4e14\u5f71\u97ff\u7bc4\u570d\u66f4\u5ee3\uff0c\u6d89\u53ca\u5c0f\u8166\u3001\u9f52\u72c0\u6838\u3001\u6a4b\u8166\u6838\u3001\u984d\u8449\u53ca\u9802\u8449\u7b49\u5340\u57df\u3002 2a\u671fPSP\u81e8\u5e8a\u8a66\u9a57\u662f\u4e00\u9805\u70ba\u671f24\u5468\u7684\u96a8\u6a5f\u3001\u96d9\u76f2\u3001\u5b89\u6170\u5291\u5c0d\u7167\u524d\u77bb\u6027\u63a2\u7d22\u6027\u81e8\u5e8a\u8a66\u9a57\uff0c\u5728\u97d3\u570b5\u500b\u7814\u7a76\u4e2d\u5fc3\u5171\u62db\u52df\u4e8678\u540dPSP\u60a3\u8005\u3002\u53c3\u8207\u8005\u63091:1:1\u7684\u6bd4\u4f8b\u96a8\u6a5f\u5206\u914d\uff0c\u5206\u5225\u63a5\u53d7\u5b89\u6170\u5291\u30010.56\u6beb\u514bGV1001\u62161.12\u6beb\u514bGV1001\u6cbb\u7642\u3002\u6cbb\u7642\u65b9\u6848\u70ba\u524d4\u5468\uff081\u500b\u6708\uff09\u6bcf\u9031\u4e00\u6b21\u76ae\u4e0b\u6ce8\u5c04\uff0c\u96a8\u5f8c\u6bcf2\u5468\u6ce8\u5c04\u4e00\u6b21\uff0c\u6301\u7e8c20\u5468\uff085\u500b\u6708\uff09\uff0c\u7e3d\u5171\u70ba\u671f24\u5468\uff086\u500b\u6708\uff09\u3002\u8a72\u8a66\u9a57\u9762\u5411PSP-RS\u548cPSP-P\u5169\u7a2e\u985e\u578b\u7684\u60a3\u8005\u958b\u653e\u3002\u8a66\u9a57\u7d50\u679c\u986f\u793a\uff0c\u4f4e\u5291\u91cf\u7d44\uff080.56\u6beb\u514b\uff09\u7642\u6548\u66f4\u70ba\u986f\u8457\uff0c\u5c24\u5176\u5c0dPSP-RS\u578b\u60a3\u8005\u6548\u679c\u66f4\u4f73\u3002 \u8a66\u9a57\u7684\u4e3b\u8981\u7d42\u9ede\u662f\u4f7f\u7528GV1001\u6cbb\u764224\u5468\u5f8cPSP\u8a55\u4efd\u91cf\u8868\u7e3d\u5206\uff08\u63a1\u7528MMRM\u6cd5\u8a08\u7b97\u7684\u6700\u5c0f\u4e8c\u4e58\u5747\u6578\uff09\u8f03\u57fa\u7dda\u7684\u8b8a\u5316\u3002\u7d50\u679c\u986f\u793a\uff0c0.56\u6beb\u514b\u5291\u91cf\u7d44\u75c5\u60c5\u60e1\u53162.14\u5206\uff0c\u800c\u5b89\u6170\u5291\u7d444.10\u5206\uff0c\u8aaa\u660e\u75be\u75c5\u9032\u7a0b\u6e1b\u7de9\u4e8648%\uff08\u898b\u57161\uff09\u3002\u5118\u7ba1\u672a\u9054\u7d71\u8a08\u5b78\u986f\u8457\u5dee\u7570\uff0c\u4f46\u9019\u4e9b\u767c\u73fe\u4ecd\u63ed\u793a\u4e86GV1001\u6cbb\u7642\u76ee\u524d\u7121\u6cd5\u6cbb\u7652\u7684PSP\u7684\u6f5b\u529b\uff0c\u4e26\u70ba\u63a8\u9032GV1001\u81f3\u66f4\u9ad8\u7d1a\u5225\u81e8\u5e8a\u8a66\u9a57\u63d0\u4f9b\u4e86\u4f9d\u64da\u3002 Figure 1. PSP-Rating Scale Total Score (PSP-RS Type + PSP-P Type_ LS mean using MMRM) \u81e8\u5e8a\u4e0a\uff0c\u591a\u6578PSP\u60a3\u8005\u5c6c\u65bc\u5178\u578b\u7684PSP-RS\u578b\uff0c\u9019\u4e00\u985e\u578b\u8f03\u5176\u4ed6PSP\u985e\u578b\u75c5\u7a0b\u9032\u5c55\u66f4\u5feb\uff0c\u5e73\u5747\u751f\u5b58\u671f\u4e5f\u66f4\u77ed\u3002\u8a66\u9a57\u5c08\u9580\u91dd\u5c0dPSP-RS\u578b\u60a3\u8005\u9032\u884c\u4e86\u5206\u7d44\u5206\u6790\u3002\u5728\u670d\u7528GV1001\u4e8c\u5341\u56db\u5468\u5f8c\uff0c\u63a1\u7528\u7c21\u55ae\u5e73\u5747\u6cd5\u8a08\u7b97PSP\u8a55\u4efd\u91cf\u8868\u7e3d\u5206\u5747\u503c\u7684\u8b8a\u5316\uff0c\u7d50\u679c\u986f\u793a\uff0c0.56\u6beb\u514b\u5291\u91cf\u7d44\u75c5\u60c5\u60e1\u5316\u5e73\u5747\u5206\u70ba0.25\u5206\uff0c\u800c\u5b89\u6170\u5291\u7d44\u70ba5.19\u5206\uff0c\u5169\u7d44\u76f8\u5dee4.94\u5206\uff0c\u8aaa\u660e\u75be\u75c5\u60e1\u5316\u7a0b\u5ea6\u964d\u4f4e\u4e8695%\uff08\u898b\u57162\uff09\u3002 Figure 2. PSP-Rating Scale Total Score (PSP-RS Type_ simple average) \u6cbb\u7642\u7d44\u4e2d\u591a\u6578PSP-RS\u578b\u60a3\u8005\u5728\u8a66\u9a57\u671f\u9593\u75c7\u72c0\u4fdd\u6301\u7a69\u5b9a\u751a\u81f3\u6709\u6240\u6539\u5584\u3002\u4ee5\u6cbb\u76426\u500b\u6708\u5f8cPSP\u8a55\u4efd\u91cf\u8868\u7e3d\u5206\u8207\u57fa\u7dda\u76f8\u6bd4\u6709\u6240\u6539\u5584\u6216\u4fdd\u6301\u7a69\u5b9a\u7684\u60a3\u8005\u6bd4\u4f8b\u4f86\u8a08\u7b97\u7de9\u89e3\u7387\uff0c0.56\u6beb\u514bGV1001\u7d44\u670958.33%\u7684PSP-RS\u578b\u60a3\u8005\u75c7\u72c0\u5f97\u5230\u4e86\u6539\u5584\u6216\u7a69\u5b9a\uff08\u898b\u57163\uff09\u3002 Figure 3. Responder Rate (PSP-RS Type) \u57282a\u671fPSP\u81e8\u5e8a\u8a66\u9a57\u4e2d\uff0cGV1001\u7684\u5b89\u5168\u6027\u8868\u73fe\u8207\u4e4b\u524d\u7684\u6578\u64da\u76f8\u7b26\uff0c\u6574\u9ad4\u8010\u53d7\u6027\u826f\u597d\uff0c\u672a\u89c0\u5bdf\u5230\u8207\u85e5\u7269\u76f8\u95dc\u7684\u56b4\u91cd\u4e0d\u826f\u4e8b\u4ef6\u3002 GemVax\u9996\u5e2d\u6230\u7565\u5b98Hyungsik Moon\u6307\u51fa\uff1a\u300c\u672c\u6b212a\u671f\u8a66\u9a57\u5c6c\u65bc\u63a2\u7d22\u6027\u7814\u7a76\uff0c\u65e8\u5728\u78ba\u5b9a\u6700\u512a\u5291\u91cf\u53ca\u591a\u80bd\u5c0d\u4e0d\u540c\u5206\u7d44\u7684\u6548\u679c\u3002\u5118\u7ba1\u9802\u7dda\u7d50\u679c\u672a\u9054\u5230\u7d71\u8a08\u5b78\u986f\u8457\u6027\uff0c\u4f46\u6240\u63d0\u4f9b\u7684\u8b49\u64da\u5df2\u5145\u5206\u652f\u6301\u6211\u5011\u8003\u616e\u63a8\u9032\u81f3\u95dc\u9375\u6027\u8a66\u9a57\uff0c\u540c\u6642\u8868\u660eGV1001\u6709\u671b\u6210\u70ba\u5168\u7403\u9996\u500bPSP\u6cbb\u7642\u65b9\u6848\u3002\u300d \u51fa\u5e2dNeuro2024\u6703\u8b70\u7684\u5c08\u5bb6\u5c0dPSP\u8a66\u9a57\u7d50\u679c\u8868\u793a\u6b61\u8fce\uff0c\u8a8d\u70ba\u6210\u679c\u632f\u596e\u4eba\u5fc3\uff0c\u4e26\u5c0d\u8a72\u85e5\u5373\u5c07\u9081\u5165\u5168\u74033\u671f\u81e8\u5e8a\u8a66\u9a57\u9032\u884c\u66f4\u6df1\u5165\u7684\u7814\u767c\u611f\u5230\u9ad8\u8208\u3002 \u5168\u7403CRO ICON\u85e5\u7269\u958b\u767c\u9ad8\u7d1a\u526f\u7e3d\u88c1\u3001\u91ab\u5b78\u535a\u58ebPeter Sch\u00fcler\u8868\u793a\uff1a\u300c\u9019\u9805\u8a66\u9a57\u6027\u7814\u7a76\u4e26\u975e\u5b8c\u5168\u6709\u6548\uff0c\u4e146\u500b\u6708\u7684\u6cbb\u7642\u9031\u671f\u76f8\u5c0d\u8f03\u77ed\uff0c\u56e0\u6b64\u7121\u6cd5\u9810\u671f\u7372\u5f97\u5177\u6709\u7d71\u8a08\u5b78\u610f\u7fa9\u7684\u78ba\u8b49\u7d50\u679c\u3002\u4e0d\u904e\uff0c\u5728\u904b\u52d5\u8868\u73fe\u548c\u8a8d\u77e5\u529f\u80fd\u9019\u5169\u500b\u9818\u57df\uff0c\u6211\u5011\u89c0\u5bdf\u5230\u7684\u8da8\u52e2\u65e2\u5408\u7406\u53c8\u4e00\u81f4\uff0c\u5747\u986f\u793a\u51fa\u4f4e\u5291\u91cf\u7d44\u7684\u512a\u52e2\u3002\u300d Sch\u00fcler\u535a\u58eb\u8868\u793a\uff1a\u300c\u672c\u6b21\u8a66\u9a57\u78ba\u5b9a\u4e86\u6700\u4f73\u5291\u91cf\uff0c\u9019\u4e5f\u662f2a\u671f\u7814\u7a76\u7684\u4e3b\u8981\u76ee\u6a19\u4e4b\u4e00\uff0c\u4e26\u5c55\u73fe\u4e86\u8207\u5b89\u6170\u5291\u7d44\u76f8\u6bd4\uff0c\u75c5\u60c5\u5b8c\u5168\u7a69\u5b9a\u9019\u4e00\u5177\u6709\u81e8\u5e8a\u610f\u7fa9\u7684\u597d\u8655\u3002\u9019\u4e9b\u9802\u7dda\u6578\u64da\u70ba\u63a8\u9032\u81f33\u671f\u7814\u7a76\u63d0\u4f9b\u4e86\u6709\u529b\u7684\u4f9d\u64da\u3002\u300d \u6155\u5c3c\u9ed1\u5927\u5b78\u9644\u5c6c\u91ab\u9662(LMU Hospital)\u795e\u7d93\u79d1\u4e3b\u4efb\u3001\u5168\u7403\u77e5\u540dPSP\u5c08\u5bb6G\u00fcnter U. H\u00f6glinger\u535a\u58eb\u8a55\u50f9\u9053\uff1a\u300c\u5728\u5168\u65b0\u4f5c\u7528\u6a5f\u5236\u7684\u65b0\u85e5\u7814\u7a76\u4e2d\uff0c\u6211\u5011\u7372\u5f97\u4e86\u6975\u70ba\u632f\u596e\u76842\u671f\u81e8\u5e8a\u6578\u64da\u3002\u5118\u7ba1\u6578\u64da\u5c1a\u5c6c\u521d\u6b65\uff0c\u4f46\u524d\u666f\u5ee3\u95ca\uff0c\u4e14\u8207[GV1001]\u5728\u963f\u723e\u8328\u6d77\u9ed8\u75c5\u4e2d\u7684\u81e8\u5e8a\u6578\u64da\u76f8\u5951\u5408\u3002\u6211\u5c0d\u63a5\u4e0b\u4f86\u7684\u7814\u767c\u5145\u6eff\u671f\u5f85\uff0c\u4e26\u5f88\u69ae\u5e78\u80fd\u53c3\u8207\u4e26\u9818\u5c0e[PSP]\u76843\u671f\u7814\u7a76\u3002\u300d CurePSP\u4e3b\u4efbKristophe Diaz\u535a\u58eb\u8868\u793a\uff1a\u300cGemVax\u6700\u8fd1\u7684\u81e8\u5e8a\u8a66\u9a57\u7d50\u679c\u4ee4\u4eba\u632f\u596e\uff0c\u70ba\u6574\u500bPSP\u7fa4\u9ad4\uff0c\u5305\u62ec\u76ee\u524d\u5c1a\u7121\u6cbb\u7642\u9078\u64c7\u7684\u60a3\u8005\u3001\u5bb6\u5c6c\u53ca\u6cbb\u7642\u4ed6\u5011\u7684\u91ab\u751f\uff0c\u5e36\u4f86\u4e86\u5e0c\u671b\u3002\u6211\u5011\u795d\u8cc0GemVax\u6210\u529f\u5b8c\u6210\u8a66\u9a57\uff0c\u4e26\u671f\u5f85\u5176\u80fd\u7e7c\u7e8c\u70baPSP\u793e\u7fa4\u5e36\u4f86\u66f4\u591a\u798f\u7949\u3002\u300d\u4ed6\u9084\u5f37\u8abf\uff1a\u300cCurePSP\u5c07\u4e00\u5982\u65e2\u5f80\u5730\u81f4\u529b\u65bc\u5408\u4f5c\uff0c\u652f\u6301\u70ba\u9019\u4e00\u6bc0\u6ec5\u6027\u75be\u75c5\u60a3\u8005\u5e36\u4f86\u5e0c\u671b\u8207\u6210\u679c\u7684\u5404\u9805\u5de5\u4f5c\u3002\u300d \u4e0b\u8f09PDF\uff1ahttps:\/\/mma.prnewswire.com\/media\/2542940\/2024_10_29__GemVax_Announces_Topline_Results.pdf \u95dc\u65bc2a\u671fPSP\u81e8\u5e8a\u8a66\u9a57(NCT05819658) 2a\u671fPSP\u81e8\u5e8a\u8a66\u9a57\u662f\u4e00\u9805\u70ba\u671f24\u5468\u7684\u591a\u4e2d\u5fc3\u3001\u96a8\u6a5f\u3001\u96d9\u76f2\u3001\u5b89\u6170\u5291\u5c0d\u7167\u524d\u77bb\u6027\u63a2\u7d22\u6027\u81e8\u5e8a\u7814\u7a76\uff0c\u65e8\u5728\u8a55\u4f300.56\u6beb\u514b\u62161.12\u6beb\u514bGV1001\u8207\u5b89\u6170\u5291\u76f8\u6bd4\u5728\u6cbb\u7642PSP\u60a3\u8005\u4e0a\u7684\u5b89\u5168\u6027\u548c\u7642\u6548\u3002\u4e3b\u8981\u7d42\u9ede\u70ba\u4f7f\u7528GV1001\u6cbb\u764224\u5468\u5f8c\uff0cPSP\u8a55\u4efd\u91cf\u8868\u7e3d\u5206\u76f8\u5c0d\u65bc\u57fa\u7dda\u7684\u8b8a\u5316\u3002\u6b21\u8981\u7d42\u9ede\u5247\u5305\u62ec3\u500b\u6708\u6642PSP\u8a55\u4efd\u91cf\u8868\u7e3d\u5206\u4ee5\u53ca3\u500b\u6708\u548c6\u500b\u6708\u6642MoCA-K\u3001K-FAB\u548cES-ADL\u8a55\u5206\u76f8\u5c0d\u65bc\u57fa\u7dda\u7684\u8b8a\u5316\u3002\u6b64\u5916\uff0c\u7814\u7a76\u9084\u5168\u9762\u8a55\u4f30\u4e86GV1001\u7684\u7e3d\u9ad4\u5b89\u5168\u6027\u3002 \u95dc\u65bcGV1001 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Ltd.\u662f\u97d3\u570b\u4e00\u5bb6\u8655\u65bc\u81e8\u5e8a\u968e\u6bb5\u7684\u751f\u7269\u88fd\u85e5\u5148\u92d2\u4f01\u696d\uff0c\u5c08\u6ce8\u65bc\u7814\u767c\u6cbb\u7642\u795e\u7d93\u9000\u884c\u6027\u75be\u75c5\uff08\u5982\u9032\u884c\u6027\u6838\u4e0a\u6027\u9ebb\u75fa\u548c\u963f\u723e\u8328\u6d77\u9ed8\u75c5\uff09\u7684\u5c08\u5229\u7642\u6cd5\u3002\u91dd\u5c0dPSP\uff0cGemVax\u6b63\u5728\u97d3\u570b\u9032\u884c2a\u671f\u7814\u7a76\uff0c\u4ee5\u8a55\u4f30GV1001\u5c0dPSP\u60a3\u8005\u7684\u7642\u6548\u8207\u5b89\u5168\u6027\uff0c\u540c\u6642\u4e5f\u5728\u7c4c\u5099\u5168\u7403\u6027\u7684PSP\u81e8\u5e8a\u8a66\u9a57\u3002\u6b64\u5916\uff0c\u516c\u53f8\u76ee\u524d\u9084\u5728\u7f8e\u570b\u548c\u6b50\u6d32\u540c\u6b65\u958b\u5c55\u963f\u723e\u8328\u6d77\u9ed8\u75c5\u76842\u671f\u81e8\u5e8a\u8a66\u9a57\u3002\u6b32\u77ad\u89e3\u66f4\u591a\u4fe1\u606f\uff0c\u8acb\u8a2a\u554fwww.gemvax.com\u4e26\u5728Linkedin\u4e0a\u95dc\u6ce8\u6211\u5011\u3002 \u524d\u77bb\u6027\u9673\u8ff0 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Ltd.\uff08\u7c21\u7a31\u300cGemVax\u300d\uff1bKOSDAQ\u80a1\u7968\u4ee3\u78bc\uff1a082270\uff09\u5728\u52a0\u62ff\u5927\u591a\u502b\u591a\u8209\u8fa6\u7684\u300cNeuro2024\uff1aPSP\u548cCBD\u570b\u969b\u7814\u7a76\u7814\u8a0e\u6703\u300d\u4e0a\u516c\u4f48\u4e86\u5176\u6cbb\u7642\u9032\u884c\u6027\u6838\u4e0a\u6027\u9ebb\u75fa(PSP)\u7684\u7814\u7a76\u7528\u591a\u80bd\u85e5\u7269GV1001\u76842a\u671f\u81e8\u5e8a\u8a66\u9a57\uff08\u7c21\u7a31\u300c2a\u671fPSP\u81e8\u5e8a\u8a66\u9a57\u300d\uff09\u7684\u9802\u7dda\u7d50\u679c\u3002 PSP\u662f\u4e00\u7a2e\u9000\u884c\u6027\u75be\u75c5\uff0c\u8207\u5e15\u91d1\u68ee\u75c5\u4e00\u6a23\uff0c\u4e5f\u6703\u5c0e\u81f4\u6b65\u614b\u969c\u7919\u3001\u65e9\u671f\u8dcc\u5012\u3001\u5782\u76f4\u6027\u51dd\u8996\u9ebb\u75fa\u3001\u50f5\u76f4\u3001\u9707\u986b\u548c\u8a8d\u77e5\u80fd\u529b\u4e0b\u964d\u7b49\u75c7\u72c0\uff0c\u4f46\u5176\u75c5\u7a0b\u9032\u5c55\u66f4\u5feb\uff0c\u76ee\u524d\u5c1a\u7121\u6839\u6cbb\u624b\u6bb5\u3002PSP\u5206\u70ba\u591a\u7a2e\u985e\u578b\uff0c\u5305\u62ecPSP-\u7406\u67e5\u68ee\u7d9c\u5408\u5f81(PSP-RS)\u548cPSP-\u5e15\u91d1\u68ee\u7d9c\u5408\u5f81(PSP-P)\u3002\u76f8\u8f03\u65bc\u5176\u4ed6\u985e\u578b\uff0cPSP-RS\u578b\u8868\u73fe\u51fa\u66f4\u70ba\u986f\u8457\u7684tau\u86cb\u767d\u805a\u96c6\uff0c\u4e14\u5f71\u97ff\u7bc4\u570d\u66f4\u5ee3\uff0c\u6d89\u53ca\u5c0f\u8166\u3001\u9f52\u72c0\u6838\u3001\u6a4b\u8166\u6838\u3001\u984d\u8449\u53ca\u9802\u8449\u7b49\u5340\u57df\u3002 2a\u671fPSP\u81e8\u5e8a\u8a66\u9a57\u662f\u4e00\u9805\u70ba\u671f24\u5468\u7684\u96a8\u6a5f\u3001\u96d9\u76f2\u3001\u5b89\u6170\u5291\u5c0d\u7167\u524d\u77bb\u6027\u63a2\u7d22\u6027\u81e8\u5e8a\u8a66\u9a57\uff0c\u5728\u97d3\u570b5\u500b\u7814\u7a76\u4e2d\u5fc3\u5171\u62db\u52df\u4e8678\u540dPSP\u60a3\u8005\u3002\u53c3\u8207\u8005\u63091:1:1\u7684\u6bd4\u4f8b\u96a8\u6a5f\u5206\u914d\uff0c\u5206\u5225\u63a5\u53d7\u5b89\u6170\u5291\u30010.56\u6beb\u514bGV1001\u62161.12\u6beb\u514bGV1001\u6cbb\u7642\u3002\u6cbb\u7642\u65b9\u6848\u70ba\u524d4\u5468\uff081\u500b\u6708\uff09\u6bcf\u9031\u4e00\u6b21\u76ae\u4e0b\u6ce8\u5c04\uff0c\u96a8\u5f8c\u6bcf2\u5468\u6ce8\u5c04\u4e00\u6b21\uff0c\u6301\u7e8c20\u5468\uff085\u500b\u6708\uff09\uff0c\u7e3d\u5171\u70ba\u671f24\u5468\uff086\u500b\u6708\uff09\u3002\u8a72\u8a66\u9a57\u9762\u5411PSP-RS\u548cPSP-P\u5169\u7a2e\u985e\u578b\u7684\u60a3\u8005\u958b\u653e\u3002\u8a66\u9a57\u7d50\u679c\u986f\u793a\uff0c\u4f4e\u5291\u91cf\u7d44\uff080.56\u6beb\u514b\uff09\u7642\u6548\u66f4\u70ba\u986f\u8457\uff0c\u5c24\u5176\u5c0dPSP-RS\u578b\u60a3\u8005\u6548\u679c\u66f4\u4f73\u3002 \u8a66\u9a57\u7684\u4e3b\u8981\u7d42\u9ede\u662f\u4f7f\u7528GV1001\u6cbb\u764224\u5468\u5f8cPSP\u8a55\u4efd\u91cf\u8868\u7e3d\u5206\uff08\u63a1\u7528MMRM\u6cd5\u8a08\u7b97\u7684\u6700\u5c0f\u4e8c\u4e58\u5747\u6578\uff09\u8f03\u57fa\u7dda\u7684\u8b8a\u5316\u3002\u7d50\u679c\u986f\u793a\uff0c0.56\u6beb\u514b\u5291\u91cf\u7d44\u75c5\u60c5\u60e1\u53162.14\u5206\uff0c\u800c\u5b89\u6170\u5291\u7d444.10\u5206\uff0c\u8aaa\u660e\u75be\u75c5\u9032\u7a0b\u6e1b\u7de9\u4e8648%\uff08\u898b\u57161\uff09\u3002\u5118\u7ba1\u672a\u9054\u7d71\u8a08\u5b78\u986f\u8457\u5dee\u7570\uff0c\u4f46\u9019\u4e9b\u767c\u73fe\u4ecd\u63ed\u793a\u4e86GV1001\u6cbb\u7642\u76ee\u524d\u7121\u6cd5\u6cbb\u7652\u7684PSP\u7684\u6f5b\u529b\uff0c\u4e26\u70ba\u63a8\u9032GV1001\u81f3\u66f4\u9ad8\u7d1a\u5225\u81e8\u5e8a\u8a66\u9a57\u63d0\u4f9b\u4e86\u4f9d\u64da\u3002 Figure 1. PSP-Rating Scale Total Score (PSP-RS Type + PSP-P Type_ LS mean using MMRM) \u81e8\u5e8a\u4e0a\uff0c\u591a\u6578PSP\u60a3\u8005\u5c6c\u65bc\u5178\u578b\u7684PSP-RS\u578b\uff0c\u9019\u4e00\u985e\u578b\u8f03\u5176\u4ed6PSP\u985e\u578b\u75c5\u7a0b\u9032\u5c55\u66f4\u5feb\uff0c\u5e73\u5747\u751f\u5b58\u671f\u4e5f\u66f4\u77ed\u3002\u8a66\u9a57\u5c08\u9580\u91dd\u5c0dPSP-RS\u578b\u60a3\u8005\u9032\u884c\u4e86\u5206\u7d44\u5206\u6790\u3002\u5728\u670d\u7528GV1001\u4e8c\u5341\u56db\u5468\u5f8c\uff0c\u63a1\u7528\u7c21\u55ae\u5e73\u5747\u6cd5\u8a08\u7b97PSP\u8a55\u4efd\u91cf\u8868\u7e3d\u5206\u5747\u503c\u7684\u8b8a\u5316\uff0c\u7d50\u679c\u986f\u793a\uff0c0.56\u6beb\u514b\u5291\u91cf\u7d44\u75c5\u60c5\u60e1\u5316\u5e73\u5747\u5206\u70ba0.25\u5206\uff0c\u800c\u5b89\u6170\u5291\u7d44\u70ba5.19\u5206\uff0c\u5169\u7d44\u76f8\u5dee4.94\u5206\uff0c\u8aaa\u660e\u75be\u75c5\u60e1\u5316\u7a0b\u5ea6\u964d\u4f4e\u4e8695%\uff08\u898b\u57162\uff09\u3002 Figure 2. PSP-Rating Scale Total Score (PSP-RS Type_ simple average) \u6cbb\u7642\u7d44\u4e2d\u591a\u6578PSP-RS\u578b\u60a3\u8005\u5728\u8a66\u9a57\u671f\u9593\u75c7\u72c0\u4fdd\u6301\u7a69\u5b9a\u751a\u81f3\u6709\u6240\u6539\u5584\u3002\u4ee5\u6cbb\u76426\u500b\u6708\u5f8cPSP\u8a55\u4efd\u91cf\u8868\u7e3d\u5206\u8207\u57fa\u7dda\u76f8\u6bd4\u6709\u6240\u6539\u5584\u6216\u4fdd\u6301\u7a69\u5b9a\u7684\u60a3\u8005\u6bd4\u4f8b\u4f86\u8a08\u7b97\u7de9\u89e3\u7387\uff0c0.56\u6beb\u514bGV1001\u7d44\u670958.33%\u7684PSP-RS\u578b\u60a3\u8005\u75c7\u72c0\u5f97\u5230\u4e86\u6539\u5584\u6216\u7a69\u5b9a\uff08\u898b\u57163\uff09\u3002 Figure 3. Responder Rate (PSP-RS Type) \u57282a\u671fPSP\u81e8\u5e8a\u8a66\u9a57\u4e2d\uff0cGV1001\u7684\u5b89\u5168\u6027\u8868\u73fe\u8207\u4e4b\u524d\u7684\u6578\u64da\u76f8\u7b26\uff0c\u6574\u9ad4\u8010\u53d7\u6027\u826f\u597d\uff0c\u672a\u89c0\u5bdf\u5230\u8207\u85e5\u7269\u76f8\u95dc\u7684\u56b4\u91cd\u4e0d\u826f\u4e8b\u4ef6\u3002 GemVax\u9996\u5e2d\u6230\u7565\u5b98Hyungsik Moon\u6307\u51fa\uff1a\u300c\u672c\u6b212a\u671f\u8a66\u9a57\u5c6c\u65bc\u63a2\u7d22\u6027\u7814\u7a76\uff0c\u65e8\u5728\u78ba\u5b9a\u6700\u512a\u5291\u91cf\u53ca\u591a\u80bd\u5c0d\u4e0d\u540c\u5206\u7d44\u7684\u6548\u679c\u3002\u5118\u7ba1\u9802\u7dda\u7d50\u679c\u672a\u9054\u5230\u7d71\u8a08\u5b78\u986f\u8457\u6027\uff0c\u4f46\u6240\u63d0\u4f9b\u7684\u8b49\u64da\u5df2\u5145\u5206\u652f\u6301\u6211\u5011\u8003\u616e\u63a8\u9032\u81f3\u95dc\u9375\u6027\u8a66\u9a57\uff0c\u540c\u6642\u8868\u660eGV1001\u6709\u671b\u6210\u70ba\u5168\u7403\u9996\u500bPSP\u6cbb\u7642\u65b9\u6848\u3002\u300d \u51fa\u5e2dNeuro2024\u6703\u8b70\u7684\u5c08\u5bb6\u5c0dPSP\u8a66\u9a57\u7d50\u679c\u8868\u793a\u6b61\u8fce\uff0c\u8a8d\u70ba\u6210\u679c\u632f\u596e\u4eba\u5fc3\uff0c\u4e26\u5c0d\u8a72\u85e5\u5373\u5c07\u9081\u5165\u5168\u74033\u671f\u81e8\u5e8a\u8a66\u9a57\u9032\u884c\u66f4\u6df1\u5165\u7684\u7814\u767c\u611f\u5230\u9ad8\u8208\u3002 \u5168\u7403CRO ICON\u85e5\u7269\u958b\u767c\u9ad8\u7d1a\u526f\u7e3d\u88c1\u3001\u91ab\u5b78\u535a\u58ebPeter Sch\u00fcler\u8868\u793a\uff1a\u300c\u9019\u9805\u8a66\u9a57\u6027\u7814\u7a76\u4e26\u975e\u5b8c\u5168\u6709\u6548\uff0c\u4e146\u500b\u6708\u7684\u6cbb\u7642\u9031\u671f\u76f8\u5c0d\u8f03\u77ed\uff0c\u56e0\u6b64\u7121\u6cd5\u9810\u671f\u7372\u5f97\u5177\u6709\u7d71\u8a08\u5b78\u610f\u7fa9\u7684\u78ba\u8b49\u7d50\u679c\u3002\u4e0d\u904e\uff0c\u5728\u904b\u52d5\u8868\u73fe\u548c\u8a8d\u77e5\u529f\u80fd\u9019\u5169\u500b\u9818\u57df\uff0c\u6211\u5011\u89c0\u5bdf\u5230\u7684\u8da8\u52e2\u65e2\u5408\u7406\u53c8\u4e00\u81f4\uff0c\u5747\u986f\u793a\u51fa\u4f4e\u5291\u91cf\u7d44\u7684\u512a\u52e2\u3002\u300d Sch\u00fcler\u535a\u58eb\u8868\u793a\uff1a\u300c\u672c\u6b21\u8a66\u9a57\u78ba\u5b9a\u4e86\u6700\u4f73\u5291\u91cf\uff0c\u9019\u4e5f\u662f2a\u671f\u7814\u7a76\u7684\u4e3b\u8981\u76ee\u6a19\u4e4b\u4e00\uff0c\u4e26\u5c55\u73fe\u4e86\u8207\u5b89\u6170\u5291\u7d44\u76f8\u6bd4\uff0c\u75c5\u60c5\u5b8c\u5168\u7a69\u5b9a\u9019\u4e00\u5177\u6709\u81e8\u5e8a\u610f\u7fa9\u7684\u597d\u8655\u3002\u9019\u4e9b\u9802\u7dda\u6578\u64da\u70ba\u63a8\u9032\u81f33\u671f\u7814\u7a76\u63d0\u4f9b\u4e86\u6709\u529b\u7684\u4f9d\u64da\u3002\u300d \u6155\u5c3c\u9ed1\u5927\u5b78\u9644\u5c6c\u91ab\u9662(LMU Hospital)\u795e\u7d93\u79d1\u4e3b\u4efb\u3001\u5168\u7403\u77e5\u540dPSP\u5c08\u5bb6G\u00fcnter U. H\u00f6glinger\u535a\u58eb\u8a55\u50f9\u9053\uff1a\u300c\u5728\u5168\u65b0\u4f5c\u7528\u6a5f\u5236\u7684\u65b0\u85e5\u7814\u7a76\u4e2d\uff0c\u6211\u5011\u7372\u5f97\u4e86\u6975\u70ba\u632f\u596e\u76842\u671f\u81e8\u5e8a\u6578\u64da\u3002\u5118\u7ba1\u6578\u64da\u5c1a\u5c6c\u521d\u6b65\uff0c\u4f46\u524d\u666f\u5ee3\u95ca\uff0c\u4e14\u8207[GV1001]\u5728\u963f\u723e\u8328\u6d77\u9ed8\u75c5\u4e2d\u7684\u81e8\u5e8a\u6578\u64da\u76f8\u5951\u5408\u3002\u6211\u5c0d\u63a5\u4e0b\u4f86\u7684\u7814\u767c\u5145\u6eff\u671f\u5f85\uff0c\u4e26\u5f88\u69ae\u5e78\u80fd\u53c3\u8207\u4e26\u9818\u5c0e[PSP]\u76843\u671f\u7814\u7a76\u3002\u300d CurePSP\u4e3b\u4efbKristophe Diaz\u535a\u58eb\u8868\u793a\uff1a\u300cGemVax\u6700\u8fd1\u7684\u81e8\u5e8a\u8a66\u9a57\u7d50\u679c\u4ee4\u4eba\u632f\u596e\uff0c\u70ba\u6574\u500bPSP\u7fa4\u9ad4\uff0c\u5305\u62ec\u76ee\u524d\u5c1a\u7121\u6cbb\u7642\u9078\u64c7\u7684\u60a3\u8005\u3001\u5bb6\u5c6c\u53ca\u6cbb\u7642\u4ed6\u5011\u7684\u91ab\u751f\uff0c\u5e36\u4f86\u4e86\u5e0c\u671b\u3002\u6211\u5011\u795d\u8cc0GemVax\u6210\u529f\u5b8c\u6210\u8a66\u9a57\uff0c\u4e26\u671f\u5f85\u5176\u80fd\u7e7c\u7e8c\u70baPSP\u793e\u7fa4\u5e36\u4f86\u66f4\u591a\u798f\u7949\u3002\u300d\u4ed6\u9084\u5f37\u8abf\uff1a\u300cCurePSP\u5c07\u4e00\u5982\u65e2\u5f80\u5730\u81f4\u529b\u65bc\u5408\u4f5c\uff0c\u652f\u6301\u70ba\u9019\u4e00\u6bc0\u6ec5\u6027\u75be\u75c5\u60a3\u8005\u5e36\u4f86\u5e0c\u671b\u8207\u6210\u679c\u7684\u5404\u9805\u5de5\u4f5c\u3002\u300d \u4e0b\u8f09PDF\uff1ahttps:\/\/mma.prnewswire.com\/media\/2542940\/2024_10_29__GemVax_Announces_Topline_Results.pdf \u95dc\u65bc2a\u671fPSP\u81e8\u5e8a\u8a66\u9a57(NCT05819658) 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\u8a66\u9a57\u7684\u4e3b\u8981\u7d42\u9ede\u662f\u4f7f\u7528GV1001\u6cbb\u764224\u5468\u5f8cPSP\u8a55\u4efd\u91cf\u8868\u7e3d\u5206\uff08\u63a1\u7528MMRM\u6cd5\u8a08\u7b97\u7684\u6700\u5c0f\u4e8c\u4e58\u5747\u6578\uff09\u8f03\u57fa\u7dda\u7684\u8b8a\u5316\u3002\u7d50\u679c\u986f\u793a\uff0c0.56\u6beb\u514b\u5291\u91cf\u7d44\u75c5\u60c5\u60e1\u53162.14\u5206\uff0c\u800c\u5b89\u6170\u5291\u7d444.10\u5206\uff0c\u8aaa\u660e\u75be\u75c5\u9032\u7a0b\u6e1b\u7de9\u4e8648%\uff08\u898b\u57161\uff09\u3002\u5118\u7ba1\u672a\u9054\u7d71\u8a08\u5b78\u986f\u8457\u5dee\u7570\uff0c\u4f46\u9019\u4e9b\u767c\u73fe\u4ecd\u63ed\u793a\u4e86GV1001\u6cbb\u7642\u76ee\u524d\u7121\u6cd5\u6cbb\u7652\u7684PSP\u7684\u6f5b\u529b\uff0c\u4e26\u70ba\u63a8\u9032GV1001\u81f3\u66f4\u9ad8\u7d1a\u5225\u81e8\u5e8a\u8a66\u9a57\u63d0\u4f9b\u4e86\u4f9d\u64da\u3002 Figure 1. PSP-Rating Scale Total Score (PSP-RS Type + PSP-P Type_ LS mean using MMRM) \u81e8\u5e8a\u4e0a\uff0c\u591a\u6578PSP\u60a3\u8005\u5c6c\u65bc\u5178\u578b\u7684PSP-RS\u578b\uff0c\u9019\u4e00\u985e\u578b\u8f03\u5176\u4ed6PSP\u985e\u578b\u75c5\u7a0b\u9032\u5c55\u66f4\u5feb\uff0c\u5e73\u5747\u751f\u5b58\u671f\u4e5f\u66f4\u77ed\u3002\u8a66\u9a57\u5c08\u9580\u91dd\u5c0dPSP-RS\u578b\u60a3\u8005\u9032\u884c\u4e86\u5206\u7d44\u5206\u6790\u3002\u5728\u670d\u7528GV1001\u4e8c\u5341\u56db\u5468\u5f8c\uff0c\u63a1\u7528\u7c21\u55ae\u5e73\u5747\u6cd5\u8a08\u7b97PSP\u8a55\u4efd\u91cf\u8868\u7e3d\u5206\u5747\u503c\u7684\u8b8a\u5316\uff0c\u7d50\u679c\u986f\u793a\uff0c0.56\u6beb\u514b\u5291\u91cf\u7d44\u75c5\u60c5\u60e1\u5316\u5e73\u5747\u5206\u70ba0.25\u5206\uff0c\u800c\u5b89\u6170\u5291\u7d44\u70ba5.19\u5206\uff0c\u5169\u7d44\u76f8\u5dee4.94\u5206\uff0c\u8aaa\u660e\u75be\u75c5\u60e1\u5316\u7a0b\u5ea6\u964d\u4f4e\u4e8695%\uff08\u898b\u57162\uff09\u3002 Figure 2. PSP-Rating Scale Total Score (PSP-RS Type_ simple average) \u6cbb\u7642\u7d44\u4e2d\u591a\u6578PSP-RS\u578b\u60a3\u8005\u5728\u8a66\u9a57\u671f\u9593\u75c7\u72c0\u4fdd\u6301\u7a69\u5b9a\u751a\u81f3\u6709\u6240\u6539\u5584\u3002\u4ee5\u6cbb\u76426\u500b\u6708\u5f8cPSP\u8a55\u4efd\u91cf\u8868\u7e3d\u5206\u8207\u57fa\u7dda\u76f8\u6bd4\u6709\u6240\u6539\u5584\u6216\u4fdd\u6301\u7a69\u5b9a\u7684\u60a3\u8005\u6bd4\u4f8b\u4f86\u8a08\u7b97\u7de9\u89e3\u7387\uff0c0.56\u6beb\u514bGV1001\u7d44\u670958.33%\u7684PSP-RS\u578b\u60a3\u8005\u75c7\u72c0\u5f97\u5230\u4e86\u6539\u5584\u6216\u7a69\u5b9a\uff08\u898b\u57163\uff09\u3002 Figure 3. Responder Rate (PSP-RS Type) \u57282a\u671fPSP\u81e8\u5e8a\u8a66\u9a57\u4e2d\uff0cGV1001\u7684\u5b89\u5168\u6027\u8868\u73fe\u8207\u4e4b\u524d\u7684\u6578\u64da\u76f8\u7b26\uff0c\u6574\u9ad4\u8010\u53d7\u6027\u826f\u597d\uff0c\u672a\u89c0\u5bdf\u5230\u8207\u85e5\u7269\u76f8\u95dc\u7684\u56b4\u91cd\u4e0d\u826f\u4e8b\u4ef6\u3002 GemVax\u9996\u5e2d\u6230\u7565\u5b98Hyungsik Moon\u6307\u51fa\uff1a\u300c\u672c\u6b212a\u671f\u8a66\u9a57\u5c6c\u65bc\u63a2\u7d22\u6027\u7814\u7a76\uff0c\u65e8\u5728\u78ba\u5b9a\u6700\u512a\u5291\u91cf\u53ca\u591a\u80bd\u5c0d\u4e0d\u540c\u5206\u7d44\u7684\u6548\u679c\u3002\u5118\u7ba1\u9802\u7dda\u7d50\u679c\u672a\u9054\u5230\u7d71\u8a08\u5b78\u986f\u8457\u6027\uff0c\u4f46\u6240\u63d0\u4f9b\u7684\u8b49\u64da\u5df2\u5145\u5206\u652f\u6301\u6211\u5011\u8003\u616e\u63a8\u9032\u81f3\u95dc\u9375\u6027\u8a66\u9a57\uff0c\u540c\u6642\u8868\u660eGV1001\u6709\u671b\u6210\u70ba\u5168\u7403\u9996\u500bPSP\u6cbb\u7642\u65b9\u6848\u3002\u300d \u51fa\u5e2dNeuro2024\u6703\u8b70\u7684\u5c08\u5bb6\u5c0dPSP\u8a66\u9a57\u7d50\u679c\u8868\u793a\u6b61\u8fce\uff0c\u8a8d\u70ba\u6210\u679c\u632f\u596e\u4eba\u5fc3\uff0c\u4e26\u5c0d\u8a72\u85e5\u5373\u5c07\u9081\u5165\u5168\u74033\u671f\u81e8\u5e8a\u8a66\u9a57\u9032\u884c\u66f4\u6df1\u5165\u7684\u7814\u767c\u611f\u5230\u9ad8\u8208\u3002 \u5168\u7403CRO ICON\u85e5\u7269\u958b\u767c\u9ad8\u7d1a\u526f\u7e3d\u88c1\u3001\u91ab\u5b78\u535a\u58ebPeter Sch\u00fcler\u8868\u793a\uff1a\u300c\u9019\u9805\u8a66\u9a57\u6027\u7814\u7a76\u4e26\u975e\u5b8c\u5168\u6709\u6548\uff0c\u4e146\u500b\u6708\u7684\u6cbb\u7642\u9031\u671f\u76f8\u5c0d\u8f03\u77ed\uff0c\u56e0\u6b64\u7121\u6cd5\u9810\u671f\u7372\u5f97\u5177\u6709\u7d71\u8a08\u5b78\u610f\u7fa9\u7684\u78ba\u8b49\u7d50\u679c\u3002\u4e0d\u904e\uff0c\u5728\u904b\u52d5\u8868\u73fe\u548c\u8a8d\u77e5\u529f\u80fd\u9019\u5169\u500b\u9818\u57df\uff0c\u6211\u5011\u89c0\u5bdf\u5230\u7684\u8da8\u52e2\u65e2\u5408\u7406\u53c8\u4e00\u81f4\uff0c\u5747\u986f\u793a\u51fa\u4f4e\u5291\u91cf\u7d44\u7684\u512a\u52e2\u3002\u300d Sch\u00fcler\u535a\u58eb\u8868\u793a\uff1a\u300c\u672c\u6b21\u8a66\u9a57\u78ba\u5b9a\u4e86\u6700\u4f73\u5291\u91cf\uff0c\u9019\u4e5f\u662f2a\u671f\u7814\u7a76\u7684\u4e3b\u8981\u76ee\u6a19\u4e4b\u4e00\uff0c\u4e26\u5c55\u73fe\u4e86\u8207\u5b89\u6170\u5291\u7d44\u76f8\u6bd4\uff0c\u75c5\u60c5\u5b8c\u5168\u7a69\u5b9a\u9019\u4e00\u5177\u6709\u81e8\u5e8a\u610f\u7fa9\u7684\u597d\u8655\u3002\u9019\u4e9b\u9802\u7dda\u6578\u64da\u70ba\u63a8\u9032\u81f33\u671f\u7814\u7a76\u63d0\u4f9b\u4e86\u6709\u529b\u7684\u4f9d\u64da\u3002\u300d \u6155\u5c3c\u9ed1\u5927\u5b78\u9644\u5c6c\u91ab\u9662(LMU Hospital)\u795e\u7d93\u79d1\u4e3b\u4efb\u3001\u5168\u7403\u77e5\u540dPSP\u5c08\u5bb6G\u00fcnter U. 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