{"id":20099,"date":"2024-06-28T04:48:00","date_gmt":"2024-06-27T20:48:00","guid":{"rendered":"https:\/\/www.franchise.com.hk\/sirnaomics%e5%ae%a3%e4%bd%88%e5%ae%8c%e6%88%90stp707%e7%9a%84i%e6%9c%9f%e8%87%a8%e5%ba%8a%e7%a0%94%e7%a9%b6-%e5%85%b6%e7%b5%90%e6%9e%9c%e5%85%b7%e6%9c%89%e8%bc%83%e5%bc%b7%e7%9a%84%e5%ae%89%e5%85%a8\/20099"},"modified":"2024-06-28T04:48:00","modified_gmt":"2024-06-27T20:48:00","slug":"sirnaomics%e5%ae%a3%e4%bd%88%e5%ae%8c%e6%88%90stp707%e7%9a%84i%e6%9c%9f%e8%87%a8%e5%ba%8a%e7%a0%94%e7%a9%b6-%e5%85%b6%e7%b5%90%e6%9e%9c%e5%85%b7%e6%9c%89%e8%bc%83%e5%bc%b7%e7%9a%84%e5%ae%89%e5%85%a8","status":"publish","type":"post","link":"https:\/\/www.franchise.com.hk\/en\/sirnaomics%e5%ae%a3%e4%bd%88%e5%ae%8c%e6%88%90stp707%e7%9a%84i%e6%9c%9f%e8%87%a8%e5%ba%8a%e7%a0%94%e7%a9%b6-%e5%85%b6%e7%b5%90%e6%9e%9c%e5%85%b7%e6%9c%89%e8%bc%83%e5%bc%b7%e7%9a%84%e5%ae%89%e5%85%a8\/20099","title":{"rendered":"Sirnaomics\u5ba3\u4f48\u5b8c\u6210STP707\u7684I\u671f\u81e8\u5e8a\u7814\u7a76 \u5176\u7d50\u679c\u5177\u6709\u8f03\u5f37\u7684\u5b89\u5168\u6027\u548c\u6cbb\u7642\u80f0\u817a\u764c\u60a3\u8005\u7a69\u5b9a\u7684\u75be\u75c5\u6d3b\u6027"},"content":{"rendered":"<p><span class=\"legendSpanClass\">\u9999\u6e2f\u7279\u5225\u884c\u653f\u5340\u3001\u7f8e\u570b\u99ac\u91cc\u862d\u5dde\u5fb7\u570b\u57ce\u548c\u4e2d\u570b\u8607\u5dde<\/span><span class=\"legendSpanClass\">2024\u5e746\u670828\u65e5<\/span> \/\u7f8e\u901a\u793e\/ &#8212; Sirnaomics Ltd.\uff08\u300c\u516c\u53f8\u300d\uff0c\u9023\u540c\u5176\u9644\u5c6c\u516c\u53f8\uff0c\u7d71\u7a31\u300c\u96c6\u5718\u300d\u6216\u300cSirnaomics\u300d\uff1b\u80a1\u4efd\u4ee3\u865f\uff1a2257\uff09\uff0c\u4e00\u5bb6\u884c\u696d\u9818\u5148\u7684\u5c08\u6ce8\u65bc\u63a2\u7d22\u53ca\u958b\u767cRNAi\u7642\u6cd5\u7684\u751f\u7269\u88fd\u85e5\u516c\u53f8\uff0c\u4eca\u65e5\u5ba3\u4f48\uff0c\u96c6\u5718\u5df2\u5b8c\u6210STP707\u7684I\u671f\u81e8\u5e8a\u7814\u7a76\uff0c\u5177\u6709\u8f03\u5f37\u7684\u5b89\u5168\u6027\u548c\u6cbb\u7642\u80f0\u817a\u764c\u60a3\u8005\u7a69\u5b9a\u7684\u75be\u75c5\u6d3b\u6027\u3002\u9019\u662f\u4e00\u9805\u5728\u7f8e\u570b11\u5bb6\u816b\u7624\u8a3a\u6240\u9032\u884c\u7684\u5291\u91cf\u905e\u589e\u7814\u7a76\u3002\u8a72\u7814\u7a76\u6d89\u53ca\u516d\u7d44\uff0c\u5305\u62ec50\u540d\u60a3\u6709\u5404\u7a2e\u764c\u75c7\u7684\u60a3\u8005\uff0c\u5176\u4e2d11\u540d\u60a3\u6709\u80f0\u817a\u764c\u3002<\/p>\n<p>\u5728\u516c\u53f8\u5148\u524d\u65bc2023\u5e748\u6708\u767c\u4f48\u7684\u65b0\u805e\u7a3f\u4e2d\uff0c\u96c6\u5718\u6307\u51fa\u5176STP707\u6cbb\u7642\u591a\u767c\u6027\u5be6\u9ad4\u7624\u7684I\u671f\u7814\u7a76\u5df2\u5b8c\u6210\u6240\u6709\u7d66\u85e5\u65b9\u6848\u3002\u9019\u662f\u4e00\u9805\u62db\u52df\u4e86\u5c0d\u591a\u8f2a\u6cbb\u7642\u5931\u6557\u7684\u591a\u985e\u578b\u665a\u671f\u764c\u75c7\u60a3\u8005\u7684\u7c43\u5f0f\u7814\u7a76\u3002\u901a\u904e\u516d\u500b\u7d44\u7684\u905e\u589e\u5291\u91cf\u975c\u8108\u6ce8\u5c04\uff08IV\uff09\uff0c\u8a72\u7814\u7a76\u65e8\u5728\u8a55\u4f30\u96c6\u5718\u7684siRNA\uff08\u5c0f\u5e72\u64feRNA\uff09\u5019\u9078\u85e5\u7269STP707\u7684\u5b89\u5168\u6027\u3001\u8010\u53d7\u6027\u548c\u6297\u816b\u7624\u6d3b\u6027\u3002\u8a72\u7814\u7a76\u62db\u52df\u4e86\u665a\u671f\u2571\u8f49\u79fb\u6027\u6216\u624b\u8853\u4e0d\u53ef\u5207\u9664\u7684\uff0c\u5c0d\u6a19\u6e96\u6cbb\u7642\u7121\u6548\u7684\u5be6\u9ad4\u7624\u60a3\u8005\uff0c\u5305\u62ec\u80f0\u817a\u764c\u3001\u7d50\u76f4\u8178\u764c\u3001\u809d\u764c\u3001\u9ed1\u8272\u7d20\u7624\u548c\u5176\u4ed6\u764c\u75c7\u60a3\u8005\u3002\u6211\u5011\u5728\u905e\u589e\u5291\u91cf\u4e2d\u63a2\u7d22\u4e86\u516d\u500b\u5291\u91cf\u6c34\u6e96\uff083mg\u30016mg\u300112mg\u300124mg\u300136mg\u548c48mg\uff09\u3002\u60a3\u8005\u572828\u5929\u9031\u671f\u4e2d\u7684\u7b2c1\u30018\u300115\u548c22\u5929\u63a5\u53d7\u975c\u8108\u8f38\u6ce8\u3002<\/p>\n<p>\u8a72\u7814\u7a76\u62db\u52df\u4e8611\u540d\u80f0\u817a\u764c\u60a3\u8005\uff085\u540d\u7537\u6027\u548c6\u540d\u5973\u6027\uff0c\u5e73\u5747\u5e74\u9f6164\u6b72\uff09\u3002\u5728\u53c3\u52a0\u7814\u7a76\u4e4b\u524d\uff0c\u60a3\u8005\u5df2\u7d93\u63a5\u53d7\u4e86\u5927\u91cf\u6cbb\u7642\uff0c\u5728\u7d0d\u5165\u7814\u7a76\u4e4b\u524d\uff0c\u5e73\u5747\u63a5\u53d7\u4e86\u4e09\u7a2e\u6cbb\u7642\u65b9\u6cd5\uff08\u5305\u62ec\u5409\u897f\u4ed6\u6ff1\u3001\u7d2b\u6749\u9187\u548cFolfirinox\uff09\u3002\u521d\u6b65\u7d50\u679c\u8868\u660e\uff0c\u5b8c\u6210\u7684\u5e73\u5747\u6cbb\u7642\u9031\u671f\u70ba\u4e09\u500b\u9031\u671f\uff08\u5e73\u574712\u5291\uff09\u3002\u6240\u670911\u4f8b\u4f7f\u7528STP707\u85e5\u7269\u7684\u60a3\u8005\u75c5\u60c5\u7a69\u5b9a\u7684\u5e73\u5747\u5929\u6578\u70ba92\u5929\uff0c12mg\u7d44\u70ba31\u5929\uff0c24mg\u7d44\u70ba65\u5929\uff0c48mg\u7d44\u70ba112\u5929\uff0c\u5176\u4e2d1\u4f8b\u60a3\u8005\u75c5\u60c5\u7a69\u5b9a\u70ba281\u5929\u300211\u4f8b\u60a3\u8005\u672a\u5831\u544a\u6cbb\u7642\u76f8\u95dc\u4e0d\u826f\u4e8b\u4ef6\uff08TRAE\uff09\uff0c\u9664\u4e861\u4f8b\u60a3\u8005\u51fa\u73fe2\u7d1a\u8f38\u6ce8\u53cd\u61c9\u3002\u975e\u6cbb\u7642\u76f8\u95dc\u4e0d\u826f\u4e8b\u4ef6\u7e7c\u767c\u65bc\u5176\u665a\u671f\u8f49\u79fb\u6027\u75be\u75c5\uff0c\u5305\u62ec\u8178\u6897\u963b\u3001\u8179\u8139\u3001\u80c3\u8178\u9053\u6897\u963b\u3001\u6813\u585e\u3001\u6d88\u5316\u9053\u51fa\u8840\u3001\u816b\u7624\u75bc\u75db\u3001\u7f3a\u6c27\u548c\u547c\u5438\u56f0\u96e3\u3002<\/p>\n<p>\u5373\u4f7f\u572848mg\u7684\u5291\u91cf\u6c34\u6e96\u4e0b\uff0c\u6240\u670950\u540d\u665a\u671f\u764c\u75c7\u60a3\u8005\u4ecd\u672a\u9054\u5230STP707\u6700\u5927\u8010\u53d7\u5291\u91cf\u3002STP707\u5728\u5df2\u7d93\u63a5\u53d7\u904e\u5927\u91cf\u6cbb\u7642\u7684\u764c\u75c7\u60a3\u8005\u7fa4\u9ad4\u4e2d\u8010\u53d7\u6027\u975e\u5e38\u597d\u300211\u540d\u80f0\u817a\u764c\u60a3\u8005\u5728\u4e0d\u540c\u5291\u91cf\u4e0b\u8868\u73fe\u51fa\u4f4e\u6bd2\u6027\u548c\u76f8\u5c0d\u7a69\u5b9a\u75be\u75c5\uff08106\u3001281\u548c302\u5929\uff09\uff0c\u9452\u65bcSTP707\u5728\u81e8\u5e8a\u524d\u8b49\u660e\u7684\u5c07T\u7d30\u80de\u52df\u96c6\u5230\u816b\u7624\u5fae\u74b0\u5883\uff08TME\uff09\u7684\u80fd\u529b\uff0c\u6211\u5011\u8a8d\u70ba\u6709\u5fc5\u8981\u55ae\u7368\u4f7f\u7528STP707\u6216\u8207\u514d\u75ab\u6aa2\u67e5\u9ede\u6291\u5236\u5291\u806f\u5408\u4f7f\u7528\u4ee5\u4f5c\u9032\u4e00\u6b65\u7814\u7a76\u3002\u9019\u662f\u57fa\u65bc\u591a\u80bd\u7d0d\u7c73\u9846\u7c92\u7684siRNA\u764c\u75c7\u6cbb\u7642\u85e5\u7269\u9996\u6b21\u5728\u6cbb\u7642\u665a\u671f\u80f0\u817a\u764c\u60a3\u8005\u65b9\u9762\u986f\u793a\u51fa\u65e9\u671f\u7a4d\u6975\u7684\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\u7d50\u679c\u3002<\/p>\n<p>\u300c\u6211\u5011\u975e\u5e38\u9ad8\u8208\u5730\u770b\u5230STP707\uff0c\u6211\u5011\u9818\u5148\u7684siRNA\u85e5\u7269\u7522\u54c1\uff0c\u7528\u65bc\u6cbb\u7642\u5df2\u7d93\u63a5\u53d7\u904e\u5927\u91cf\u6cbb\u7642\u7684\u80f0\u817a\u764c\uff08\u6700\u81f4\u547d\u7684\u816b\u7624\u985e\u578b\u4e4b\u4e00\uff09\uff0c\u5728\u975c\u8108\u7d66\u85e5\u5f8c\u986f\u793a\u51fa\u9019\u4e9b\u5f37\u5927\u7684\u7d50\u679c\u3002\u5c0d\u65bc\u57fa\u65bcRNAi\u7684\u764c\u75c7\u7642\u6cd5\u6cbb\u7642\u8f49\u79fb\u6027\u816b\u7624\u4f86\u8aaa\uff0c\u9019\u662f\u4e00\u500b\u975e\u5e38\u6709\u524d\u666f\u7684\u7d50\u679c\u300d\uff0cSirnaomics\u5275\u59cb\u4eba\u3001\u8463\u4e8b\u6703\u4e3b\u5e2d\u3001\u57f7\u884c\u8463\u4e8b\u3001\u7e3d\u88c1\u517c\u9996\u5e2d\u57f7\u884c\u5b98\u9678\u967d\u535a\u58eb\u8aaa\u3002\u300c\u9019\u7a2e\u975c\u8108\u6ce8\u5c04\u7684STP707\u5236\u5291\u5177\u6709\u5f37\u5927\u7684\u5b89\u5168\u6027\u3001\u6301\u4e45\u7a69\u5b9a\u7684\u75be\u75c5\u7642\u6548\u548c\u5291\u91cf\u4f9d\u8cf4\u6027\u6297\u816b\u7624\u6d3b\u6027\uff0c\u7121\u8ad6\u662f\u4f5c\u70ba\u55ae\u4e00\u85e5\u7269\u9084\u662f\u8207\u514d\u75ab\u6aa2\u67e5\u9ede\u6291\u5236\u5291\u85e5\u7269\u806f\u5408\u4f7f\u7528\uff0c\u90fd\u662f\u4e00\u7a2e\u6f5b\u5728\u7684\u65b0\u578b\u764c\u75c7\u6cbb\u7642\u65b9\u6cd5\u3002\u300d<\/p>\n<p>\u5982\u6b32\u4e86\u89e3\u6709\u95dcSirnaomics\u81e8\u5e8a\u8a66\u9a57\u7684\u5176\u4ed6\u76f8\u95dc\u4fe1\u606f\uff0c\u8acb\u700f\u89bdClinicalTrials.gov\uff08\u8b58\u5225\u78bc\uff1aNCT05037149\uff09\uff0c\u548c\u516c\u53f8\u7db2\u7ad9www.sirnaomics.com\u3002<\/p>\n<p>\u95dc\u65bcSTP707<\/p>\n<p>STP707\u7531\u9776\u5411TGF-\u03b21\u548cCOX-2 mRNA\u7684\u5169\u500bsiRNA\u5be1\u6838\u7518\u9178\u7d44\u6210\uff0c\u4e26\u8207\u7d44\u6c28\u9178\u8cf4\u6c28\u9178\u5171\u805a\u80bd\uff08HKP+H\uff09\u7684\u8f09\u9ad4\u7d50\u5408\u914d\u88fd\u6210\u7d0d\u7c73\u9846\u7c92\u88fd\u5291\u3002\u9019\u7a2e\u7279\u5b9a\u7684\u591a\u80bd\u8f09\u9ad4\u8207STP705\u6240\u7528\u7684\u8f09\u9ad4\u4e0d\u540c\u3002\u6bcf\u500b\u55ae\u7368\u7684siRNA\u90fd\u5177\u5099\u6291\u5236\u76f8\u61c9\u9776\u9edemRNA\u8868\u9054\u7684\u80fd\u529b\u3002\u800cSTP707\u53ef\u540c\u6642\u6291\u5236TGF-\u03b21\u548cCOX-2\u7684\u8868\u9054\uff0c\u5f9e\u800c\u7522\u751f\u5354\u540c\u6548\u61c9\uff0c\u6e1b\u5c11\u708e\u75c7\u53cd\u61c9\u3002\u4e14TGF-\u03b21\u548cCOX-2\u7684\u904e\u5ea6\u8868\u9054\u5df2\u88ab\u8b49\u5be6\u5728\u816b\u7624\u5f62\u6210\u4e2d\u8d77\u8457\u95dc\u9375\u7684\u8abf\u7bc0\u4f5c\u7528\u3002\u5728STP707\u7684\u4e00\u9805\u81e8\u5e8a\u524d\u7814\u7a76\u4e2d\uff0c\u975c\u8108\u6ce8\u5c04\u7d66\u85e5\u5f8c\u53ef\u89c0\u5bdf\u5230\u5305\u62ec\u809d\u81df\u3001\u80ba\u548c\u7570\u7a2e\u79fb\u690d\u7624\u7b49\u5668\u5b98\u4e2d\u7684TGF-\u03b21\u548cCOX-2\u57fa\u56e0\u8868\u9054\u88ab\u6572\u4f4e\u3002\u6b64\u5916\uff0c\u5728\u591a\u500b\u81e8\u5e8a\u524d\u6a21\u578b\u4e2d\uff0cSTP707\u986f\u793a\u51fa\u5c0d\u591a\u7a2e\u5be6\u9ad4\u816b\u7624\u985e\u578b\u5f37\u5927\u7684\u6297\u816b\u7624\u6d3b\u6027\u3002\u5728\u5c0f\u9f20\u539f\u4f4d\u809d\u764c\u6a21\u578b\u4e2d\uff0cSTP707\u548c\u514d\u75ab\u6aa2\u67e5\u9ede\u6297\u9ad4\u806f\u7528\uff0c\u5177\u6709\u5354\u540c\u7684\u6297\u816b\u7624\u6d3b\u6027\u3002<\/p>\n<p>\u95dc\u65bcSirnaomics<\/p>\n<p>Sirnaomics\u662f\u4e00\u5bb6RNA\u7642\u6cd5\u751f\u7269\u88fd\u85e5\u516c\u53f8\uff0c\u516c\u53f8\u5019\u9078\u7522\u54c1\u8655\u65bc\u81e8\u5e8a\u53ca\u81e8\u5e8a\u524d\u968e\u6bb5\uff0c\u5c08\u6ce8\u65bc\u63a2\u7d22\u53ca\u958b\u767c\u5275\u65b0\u85e5\u7269\uff0c\u7528\u65bc\u6cbb\u7642\u5177\u6709\u91ab\u7642\u9700\u6c42\u53ca\u9f90\u5927\u5e02\u5834\u6a5f\u6703\u7684\u9069\u61c9\u75c7\u3002Sirnaomics\u662f\u9996\u5bb6\u65bc\u4e9e\u6d32\u548c\u7f8e\u570b\u5747\u64c1\u6709\u91cd\u8981\u5e02\u5834\u5730\u4f4d\u7684\u81e8\u5e8a\u968e\u6bb5RNA\u7642\u6cd5\u751f\u7269\u88fd\u85e5\u516c\u53f8\u3002\u6191\u85c9\u5176\u5c08\u6709\u7684\u905e\u9001\u6280\u8853\uff1a\u591a\u80bd\u7d0d\u7c73\u9846\u7c92\u905e\u9001\u5e73\u53f0\u548c\u7b2c\u4e8c\u4ee3GalNAc\u5076\u806f\u7269\u905e\u9001\u5e73\u53f0\uff0c\u672c\u96c6\u5718\u5df2\u5efa\u7acb\u975e\u5e38\u8c50\u5bcc\u7684\u5019\u9078\u85e5\u7269\u7ba1\u7dda\u3002\u96a8\u8457\u516c\u53f8STP705\u548cSTP707\u7684\u81e8\u5e8a\u9805\u76ee\u53d6\u5f97\u591a\u9805\u6210\u529f\uff0cSirnaomics\u76ee\u524d\u5728\u63a8\u9032\u816b\u7624\u6cbb\u7642\u7684RNAi\u85e5\u7269\u65b9\u9762\u8655\u65bc\u570b\u969b\u9818\u5148\u5730\u4f4d\u3002STP122G\u662f\u9996\u6b3e\u9032\u5165\u81e8\u5e8a\u7814\u767c\u968e\u6bb5\u7684GalAhead\u2122\u6280\u8853\u5019\u9078\u85e5\u7269\u3002\u96a8\u8457Sirnaomics\u81e8\u5e8a\u751f\u7522\u8a2d\u65bd\u7684\u5efa\u7acb\uff0c\u672c\u96c6\u5718\u76ee\u524d\u6b63\u5728\u5be6\u73fe\u5f9e\u751f\u7269\u79d1\u6280\u516c\u53f8\u5411\u751f\u7269\u88fd\u85e5\u516c\u53f8\u7684\u8e8d\u9032\u3002\u5982\u6b32\u4e86\u89e3\u66f4\u591a\u95dc\u65bc\u516c\u53f8\u8cc7\u8a0a\uff0c\u53ef\u700f\u89bd\uff1awww.sirnaomics.com\u3002<\/p>\n<p>\u00a0<\/p>","protected":false},"excerpt":{"rendered":"<p>\u9999\u6e2f\u7279\u5225\u884c\u653f\u5340\u3001\u7f8e\u570b\u99ac\u91cc\u862d\u5dde\u5fb7\u570b\u57ce\u548c\u4e2d\u570b\u8607\u5dde2024\u5e746\u670828\u65e5 \/\u7f8e\u901a\u793e\/ &#8212; Sirnaomics Ltd.\uff08\u300c\u516c\u53f8\u300d\uff0c\u9023\u540c\u5176\u9644\u5c6c\u516c\u53f8\uff0c\u7d71\u7a31\u300c\u96c6\u5718\u300d\u6216\u300cSirnaomics\u300d\uff1b\u80a1\u4efd\u4ee3\u865f\uff1a2257\uff09\uff0c\u4e00\u5bb6\u884c\u696d\u9818\u5148\u7684\u5c08\u6ce8\u65bc\u63a2\u7d22\u53ca\u958b\u767cRNAi\u7642\u6cd5\u7684\u751f\u7269\u88fd\u85e5\u516c\u53f8\uff0c\u4eca\u65e5\u5ba3\u4f48\uff0c\u96c6\u5718\u5df2\u5b8c\u6210STP707\u7684I\u671f\u81e8\u5e8a\u7814\u7a76\uff0c\u5177\u6709\u8f03\u5f37\u7684\u5b89\u5168\u6027\u548c\u6cbb\u7642\u80f0\u817a\u764c\u60a3\u8005\u7a69\u5b9a\u7684\u75be\u75c5\u6d3b\u6027\u3002\u9019\u662f\u4e00\u9805\u5728\u7f8e\u570b11\u5bb6\u816b\u7624\u8a3a\u6240\u9032\u884c\u7684\u5291\u91cf\u905e\u589e\u7814\u7a76\u3002\u8a72\u7814\u7a76\u6d89\u53ca\u516d\u7d44\uff0c\u5305\u62ec50\u540d\u60a3\u6709\u5404\u7a2e\u764c\u75c7\u7684\u60a3\u8005\uff0c\u5176\u4e2d11\u540d\u60a3\u6709\u80f0\u817a\u764c\u3002 \u5728\u516c\u53f8\u5148\u524d\u65bc2023\u5e748\u6708\u767c\u4f48\u7684\u65b0\u805e\u7a3f\u4e2d\uff0c\u96c6\u5718\u6307\u51fa\u5176STP707\u6cbb\u7642\u591a\u767c\u6027\u5be6\u9ad4\u7624\u7684I\u671f\u7814\u7a76\u5df2\u5b8c\u6210\u6240\u6709\u7d66\u85e5\u65b9\u6848\u3002\u9019\u662f\u4e00\u9805\u62db\u52df\u4e86\u5c0d\u591a\u8f2a\u6cbb\u7642\u5931\u6557\u7684\u591a\u985e\u578b\u665a\u671f\u764c\u75c7\u60a3\u8005\u7684\u7c43\u5f0f\u7814\u7a76\u3002\u901a\u904e\u516d\u500b\u7d44\u7684\u905e\u589e\u5291\u91cf\u975c\u8108\u6ce8\u5c04\uff08IV\uff09\uff0c\u8a72\u7814\u7a76\u65e8\u5728\u8a55\u4f30\u96c6\u5718\u7684siRNA\uff08\u5c0f\u5e72\u64feRNA\uff09\u5019\u9078\u85e5\u7269STP707\u7684\u5b89\u5168\u6027\u3001\u8010\u53d7\u6027\u548c\u6297\u816b\u7624\u6d3b\u6027\u3002\u8a72\u7814\u7a76\u62db\u52df\u4e86\u665a\u671f\u2571\u8f49\u79fb\u6027\u6216\u624b\u8853\u4e0d\u53ef\u5207\u9664\u7684\uff0c\u5c0d\u6a19\u6e96\u6cbb\u7642\u7121\u6548\u7684\u5be6\u9ad4\u7624\u60a3\u8005\uff0c\u5305\u62ec\u80f0\u817a\u764c\u3001\u7d50\u76f4\u8178\u764c\u3001\u809d\u764c\u3001\u9ed1\u8272\u7d20\u7624\u548c\u5176\u4ed6\u764c\u75c7\u60a3\u8005\u3002\u6211\u5011\u5728\u905e\u589e\u5291\u91cf\u4e2d\u63a2\u7d22\u4e86\u516d\u500b\u5291\u91cf\u6c34\u6e96\uff083mg\u30016mg\u300112mg\u300124mg\u300136mg\u548c48mg\uff09\u3002\u60a3\u8005\u572828\u5929\u9031\u671f\u4e2d\u7684\u7b2c1\u30018\u300115\u548c22\u5929\u63a5\u53d7\u975c\u8108\u8f38\u6ce8\u3002 \u8a72\u7814\u7a76\u62db\u52df\u4e8611\u540d\u80f0\u817a\u764c\u60a3\u8005\uff085\u540d\u7537\u6027\u548c6\u540d\u5973\u6027\uff0c\u5e73\u5747\u5e74\u9f6164\u6b72\uff09\u3002\u5728\u53c3\u52a0\u7814\u7a76\u4e4b\u524d\uff0c\u60a3\u8005\u5df2\u7d93\u63a5\u53d7\u4e86\u5927\u91cf\u6cbb\u7642\uff0c\u5728\u7d0d\u5165\u7814\u7a76\u4e4b\u524d\uff0c\u5e73\u5747\u63a5\u53d7\u4e86\u4e09\u7a2e\u6cbb\u7642\u65b9\u6cd5\uff08\u5305\u62ec\u5409\u897f\u4ed6\u6ff1\u3001\u7d2b\u6749\u9187\u548cFolfirinox\uff09\u3002\u521d\u6b65\u7d50\u679c\u8868\u660e\uff0c\u5b8c\u6210\u7684\u5e73\u5747\u6cbb\u7642\u9031\u671f\u70ba\u4e09\u500b\u9031\u671f\uff08\u5e73\u574712\u5291\uff09\u3002\u6240\u670911\u4f8b\u4f7f\u7528STP707\u85e5\u7269\u7684\u60a3\u8005\u75c5\u60c5\u7a69\u5b9a\u7684\u5e73\u5747\u5929\u6578\u70ba92\u5929\uff0c12mg\u7d44\u70ba31\u5929\uff0c24mg\u7d44\u70ba65\u5929\uff0c48mg\u7d44\u70ba112\u5929\uff0c\u5176\u4e2d1\u4f8b\u60a3\u8005\u75c5\u60c5\u7a69\u5b9a\u70ba281\u5929\u300211\u4f8b\u60a3\u8005\u672a\u5831\u544a\u6cbb\u7642\u76f8\u95dc\u4e0d\u826f\u4e8b\u4ef6\uff08TRAE\uff09\uff0c\u9664\u4e861\u4f8b\u60a3\u8005\u51fa\u73fe2\u7d1a\u8f38\u6ce8\u53cd\u61c9\u3002\u975e\u6cbb\u7642\u76f8\u95dc\u4e0d\u826f\u4e8b\u4ef6\u7e7c\u767c\u65bc\u5176\u665a\u671f\u8f49\u79fb\u6027\u75be\u75c5\uff0c\u5305\u62ec\u8178\u6897\u963b\u3001\u8179\u8139\u3001\u80c3\u8178\u9053\u6897\u963b\u3001\u6813\u585e\u3001\u6d88\u5316\u9053\u51fa\u8840\u3001\u816b\u7624\u75bc\u75db\u3001\u7f3a\u6c27\u548c\u547c\u5438\u56f0\u96e3\u3002 \u5373\u4f7f\u572848mg\u7684\u5291\u91cf\u6c34\u6e96\u4e0b\uff0c\u6240\u670950\u540d\u665a\u671f\u764c\u75c7\u60a3\u8005\u4ecd\u672a\u9054\u5230STP707\u6700\u5927\u8010\u53d7\u5291\u91cf\u3002STP707\u5728\u5df2\u7d93\u63a5\u53d7\u904e\u5927\u91cf\u6cbb\u7642\u7684\u764c\u75c7\u60a3\u8005\u7fa4\u9ad4\u4e2d\u8010\u53d7\u6027\u975e\u5e38\u597d\u300211\u540d\u80f0\u817a\u764c\u60a3\u8005\u5728\u4e0d\u540c\u5291\u91cf\u4e0b\u8868\u73fe\u51fa\u4f4e\u6bd2\u6027\u548c\u76f8\u5c0d\u7a69\u5b9a\u75be\u75c5\uff08106\u3001281\u548c302\u5929\uff09\uff0c\u9452\u65bcSTP707\u5728\u81e8\u5e8a\u524d\u8b49\u660e\u7684\u5c07T\u7d30\u80de\u52df\u96c6\u5230\u816b\u7624\u5fae\u74b0\u5883\uff08TME\uff09\u7684\u80fd\u529b\uff0c\u6211\u5011\u8a8d\u70ba\u6709\u5fc5\u8981\u55ae\u7368\u4f7f\u7528STP707\u6216\u8207\u514d\u75ab\u6aa2\u67e5\u9ede\u6291\u5236\u5291\u806f\u5408\u4f7f\u7528\u4ee5\u4f5c\u9032\u4e00\u6b65\u7814\u7a76\u3002\u9019\u662f\u57fa\u65bc\u591a\u80bd\u7d0d\u7c73\u9846\u7c92\u7684siRNA\u764c\u75c7\u6cbb\u7642\u85e5\u7269\u9996\u6b21\u5728\u6cbb\u7642\u665a\u671f\u80f0\u817a\u764c\u60a3\u8005\u65b9\u9762\u986f\u793a\u51fa\u65e9\u671f\u7a4d\u6975\u7684\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\u7d50\u679c\u3002 \u300c\u6211\u5011\u975e\u5e38\u9ad8\u8208\u5730\u770b\u5230STP707\uff0c\u6211\u5011\u9818\u5148\u7684siRNA\u85e5\u7269\u7522\u54c1\uff0c\u7528\u65bc\u6cbb\u7642\u5df2\u7d93\u63a5\u53d7\u904e\u5927\u91cf\u6cbb\u7642\u7684\u80f0\u817a\u764c\uff08\u6700\u81f4\u547d\u7684\u816b\u7624\u985e\u578b\u4e4b\u4e00\uff09\uff0c\u5728\u975c\u8108\u7d66\u85e5\u5f8c\u986f\u793a\u51fa\u9019\u4e9b\u5f37\u5927\u7684\u7d50\u679c\u3002\u5c0d\u65bc\u57fa\u65bcRNAi\u7684\u764c\u75c7\u7642\u6cd5\u6cbb\u7642\u8f49\u79fb\u6027\u816b\u7624\u4f86\u8aaa\uff0c\u9019\u662f\u4e00\u500b\u975e\u5e38\u6709\u524d\u666f\u7684\u7d50\u679c\u300d\uff0cSirnaomics\u5275\u59cb\u4eba\u3001\u8463\u4e8b\u6703\u4e3b\u5e2d\u3001\u57f7\u884c\u8463\u4e8b\u3001\u7e3d\u88c1\u517c\u9996\u5e2d\u57f7\u884c\u5b98\u9678\u967d\u535a\u58eb\u8aaa\u3002\u300c\u9019\u7a2e\u975c\u8108\u6ce8\u5c04\u7684STP707\u5236\u5291\u5177\u6709\u5f37\u5927\u7684\u5b89\u5168\u6027\u3001\u6301\u4e45\u7a69\u5b9a\u7684\u75be\u75c5\u7642\u6548\u548c\u5291\u91cf\u4f9d\u8cf4\u6027\u6297\u816b\u7624\u6d3b\u6027\uff0c\u7121\u8ad6\u662f\u4f5c\u70ba\u55ae\u4e00\u85e5\u7269\u9084\u662f\u8207\u514d\u75ab\u6aa2\u67e5\u9ede\u6291\u5236\u5291\u85e5\u7269\u806f\u5408\u4f7f\u7528\uff0c\u90fd\u662f\u4e00\u7a2e\u6f5b\u5728\u7684\u65b0\u578b\u764c\u75c7\u6cbb\u7642\u65b9\u6cd5\u3002\u300d \u5982\u6b32\u4e86\u89e3\u6709\u95dcSirnaomics\u81e8\u5e8a\u8a66\u9a57\u7684\u5176\u4ed6\u76f8\u95dc\u4fe1\u606f\uff0c\u8acb\u700f\u89bdClinicalTrials.gov\uff08\u8b58\u5225\u78bc\uff1aNCT05037149\uff09\uff0c\u548c\u516c\u53f8\u7db2\u7ad9www.sirnaomics.com\u3002 \u95dc\u65bcSTP707 STP707\u7531\u9776\u5411TGF-\u03b21\u548cCOX-2 mRNA\u7684\u5169\u500bsiRNA\u5be1\u6838\u7518\u9178\u7d44\u6210\uff0c\u4e26\u8207\u7d44\u6c28\u9178\u8cf4\u6c28\u9178\u5171\u805a\u80bd\uff08HKP+H\uff09\u7684\u8f09\u9ad4\u7d50\u5408\u914d\u88fd\u6210\u7d0d\u7c73\u9846\u7c92\u88fd\u5291\u3002\u9019\u7a2e\u7279\u5b9a\u7684\u591a\u80bd\u8f09\u9ad4\u8207STP705\u6240\u7528\u7684\u8f09\u9ad4\u4e0d\u540c\u3002\u6bcf\u500b\u55ae\u7368\u7684siRNA\u90fd\u5177\u5099\u6291\u5236\u76f8\u61c9\u9776\u9edemRNA\u8868\u9054\u7684\u80fd\u529b\u3002\u800cSTP707\u53ef\u540c\u6642\u6291\u5236TGF-\u03b21\u548cCOX-2\u7684\u8868\u9054\uff0c\u5f9e\u800c\u7522\u751f\u5354\u540c\u6548\u61c9\uff0c\u6e1b\u5c11\u708e\u75c7\u53cd\u61c9\u3002\u4e14TGF-\u03b21\u548cCOX-2\u7684\u904e\u5ea6\u8868\u9054\u5df2\u88ab\u8b49\u5be6\u5728\u816b\u7624\u5f62\u6210\u4e2d\u8d77\u8457\u95dc\u9375\u7684\u8abf\u7bc0\u4f5c\u7528\u3002\u5728STP707\u7684\u4e00\u9805\u81e8\u5e8a\u524d\u7814\u7a76\u4e2d\uff0c\u975c\u8108\u6ce8\u5c04\u7d66\u85e5\u5f8c\u53ef\u89c0\u5bdf\u5230\u5305\u62ec\u809d\u81df\u3001\u80ba\u548c\u7570\u7a2e\u79fb\u690d\u7624\u7b49\u5668\u5b98\u4e2d\u7684TGF-\u03b21\u548cCOX-2\u57fa\u56e0\u8868\u9054\u88ab\u6572\u4f4e\u3002\u6b64\u5916\uff0c\u5728\u591a\u500b\u81e8\u5e8a\u524d\u6a21\u578b\u4e2d\uff0cSTP707\u986f\u793a\u51fa\u5c0d\u591a\u7a2e\u5be6\u9ad4\u816b\u7624\u985e\u578b\u5f37\u5927\u7684\u6297\u816b\u7624\u6d3b\u6027\u3002\u5728\u5c0f\u9f20\u539f\u4f4d\u809d\u764c\u6a21\u578b\u4e2d\uff0cSTP707\u548c\u514d\u75ab\u6aa2\u67e5\u9ede\u6297\u9ad4\u806f\u7528\uff0c\u5177\u6709\u5354\u540c\u7684\u6297\u816b\u7624\u6d3b\u6027\u3002 \u95dc\u65bcSirnaomics Sirnaomics\u662f\u4e00\u5bb6RNA\u7642\u6cd5\u751f\u7269\u88fd\u85e5\u516c\u53f8\uff0c\u516c\u53f8\u5019\u9078\u7522\u54c1\u8655\u65bc\u81e8\u5e8a\u53ca\u81e8\u5e8a\u524d\u968e\u6bb5\uff0c\u5c08\u6ce8\u65bc\u63a2\u7d22\u53ca\u958b\u767c\u5275\u65b0\u85e5\u7269\uff0c\u7528\u65bc\u6cbb\u7642\u5177\u6709\u91ab\u7642\u9700\u6c42\u53ca\u9f90\u5927\u5e02\u5834\u6a5f\u6703\u7684\u9069\u61c9\u75c7\u3002Sirnaomics\u662f\u9996\u5bb6\u65bc\u4e9e\u6d32\u548c\u7f8e\u570b\u5747\u64c1\u6709\u91cd\u8981\u5e02\u5834\u5730\u4f4d\u7684\u81e8\u5e8a\u968e\u6bb5RNA\u7642\u6cd5\u751f\u7269\u88fd\u85e5\u516c\u53f8\u3002\u6191\u85c9\u5176\u5c08\u6709\u7684\u905e\u9001\u6280\u8853\uff1a\u591a\u80bd\u7d0d\u7c73\u9846\u7c92\u905e\u9001\u5e73\u53f0\u548c\u7b2c\u4e8c\u4ee3GalNAc\u5076\u806f\u7269\u905e\u9001\u5e73\u53f0\uff0c\u672c\u96c6\u5718\u5df2\u5efa\u7acb\u975e\u5e38\u8c50\u5bcc\u7684\u5019\u9078\u85e5\u7269\u7ba1\u7dda\u3002\u96a8\u8457\u516c\u53f8STP705\u548cSTP707\u7684\u81e8\u5e8a\u9805\u76ee\u53d6\u5f97\u591a\u9805\u6210\u529f\uff0cSirnaomics\u76ee\u524d\u5728\u63a8\u9032\u816b\u7624\u6cbb\u7642\u7684RNAi\u85e5\u7269\u65b9\u9762\u8655\u65bc\u570b\u969b\u9818\u5148\u5730\u4f4d\u3002STP122G\u662f\u9996\u6b3e\u9032\u5165\u81e8\u5e8a\u7814\u767c\u968e\u6bb5\u7684GalAhead\u2122\u6280\u8853\u5019\u9078\u85e5\u7269\u3002\u96a8\u8457Sirnaomics\u81e8\u5e8a\u751f\u7522\u8a2d\u65bd\u7684\u5efa\u7acb\uff0c\u672c\u96c6\u5718\u76ee\u524d\u6b63\u5728\u5be6\u73fe\u5f9e\u751f\u7269\u79d1\u6280\u516c\u53f8\u5411\u751f\u7269\u88fd\u85e5\u516c\u53f8\u7684\u8e8d\u9032\u3002\u5982\u6b32\u4e86\u89e3\u66f4\u591a\u95dc\u65bc\u516c\u53f8\u8cc7\u8a0a\uff0c\u53ef\u700f\u89bd\uff1awww.sirnaomics.com\u3002 \u00a0<\/p>\n","protected":false},"author":0,"featured_media":0,"comment_status":"","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_generate-full-width-content":"","spay_email":"","footnotes":""},"categories":[1],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v20.4 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Sirnaomics\u5ba3\u4f48\u5b8c\u6210STP707\u7684I\u671f\u81e8\u5e8a\u7814\u7a76 \u5176\u7d50\u679c\u5177\u6709\u8f03\u5f37\u7684\u5b89\u5168\u6027\u548c\u6cbb\u7642\u80f0\u817a\u764c\u60a3\u8005\u7a69\u5b9a\u7684\u75be\u75c5\u6d3b\u6027 - \u9999\u6e2f\u7279\u8a31\u7d93\u71df<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.franchise.com.hk\/en\/sirnaomics%e5%ae%a3%e4%bd%88%e5%ae%8c%e6%88%90stp707%e7%9a%84i%e6%9c%9f%e8%87%a8%e5%ba%8a%e7%a0%94%e7%a9%b6-%e5%85%b6%e7%b5%90%e6%9e%9c%e5%85%b7%e6%9c%89%e8%bc%83%e5%bc%b7%e7%9a%84%e5%ae%89%e5%85%a8\/20099\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Sirnaomics\u5ba3\u4f48\u5b8c\u6210STP707\u7684I\u671f\u81e8\u5e8a\u7814\u7a76 \u5176\u7d50\u679c\u5177\u6709\u8f03\u5f37\u7684\u5b89\u5168\u6027\u548c\u6cbb\u7642\u80f0\u817a\u764c\u60a3\u8005\u7a69\u5b9a\u7684\u75be\u75c5\u6d3b\u6027 - \u9999\u6e2f\u7279\u8a31\u7d93\u71df\" \/>\n<meta property=\"og:description\" content=\"\u9999\u6e2f\u7279\u5225\u884c\u653f\u5340\u3001\u7f8e\u570b\u99ac\u91cc\u862d\u5dde\u5fb7\u570b\u57ce\u548c\u4e2d\u570b\u8607\u5dde2024\u5e746\u670828\u65e5 \/\u7f8e\u901a\u793e\/ &#8212; Sirnaomics Ltd.\uff08\u300c\u516c\u53f8\u300d\uff0c\u9023\u540c\u5176\u9644\u5c6c\u516c\u53f8\uff0c\u7d71\u7a31\u300c\u96c6\u5718\u300d\u6216\u300cSirnaomics\u300d\uff1b\u80a1\u4efd\u4ee3\u865f\uff1a2257\uff09\uff0c\u4e00\u5bb6\u884c\u696d\u9818\u5148\u7684\u5c08\u6ce8\u65bc\u63a2\u7d22\u53ca\u958b\u767cRNAi\u7642\u6cd5\u7684\u751f\u7269\u88fd\u85e5\u516c\u53f8\uff0c\u4eca\u65e5\u5ba3\u4f48\uff0c\u96c6\u5718\u5df2\u5b8c\u6210STP707\u7684I\u671f\u81e8\u5e8a\u7814\u7a76\uff0c\u5177\u6709\u8f03\u5f37\u7684\u5b89\u5168\u6027\u548c\u6cbb\u7642\u80f0\u817a\u764c\u60a3\u8005\u7a69\u5b9a\u7684\u75be\u75c5\u6d3b\u6027\u3002\u9019\u662f\u4e00\u9805\u5728\u7f8e\u570b11\u5bb6\u816b\u7624\u8a3a\u6240\u9032\u884c\u7684\u5291\u91cf\u905e\u589e\u7814\u7a76\u3002\u8a72\u7814\u7a76\u6d89\u53ca\u516d\u7d44\uff0c\u5305\u62ec50\u540d\u60a3\u6709\u5404\u7a2e\u764c\u75c7\u7684\u60a3\u8005\uff0c\u5176\u4e2d11\u540d\u60a3\u6709\u80f0\u817a\u764c\u3002 \u5728\u516c\u53f8\u5148\u524d\u65bc2023\u5e748\u6708\u767c\u4f48\u7684\u65b0\u805e\u7a3f\u4e2d\uff0c\u96c6\u5718\u6307\u51fa\u5176STP707\u6cbb\u7642\u591a\u767c\u6027\u5be6\u9ad4\u7624\u7684I\u671f\u7814\u7a76\u5df2\u5b8c\u6210\u6240\u6709\u7d66\u85e5\u65b9\u6848\u3002\u9019\u662f\u4e00\u9805\u62db\u52df\u4e86\u5c0d\u591a\u8f2a\u6cbb\u7642\u5931\u6557\u7684\u591a\u985e\u578b\u665a\u671f\u764c\u75c7\u60a3\u8005\u7684\u7c43\u5f0f\u7814\u7a76\u3002\u901a\u904e\u516d\u500b\u7d44\u7684\u905e\u589e\u5291\u91cf\u975c\u8108\u6ce8\u5c04\uff08IV\uff09\uff0c\u8a72\u7814\u7a76\u65e8\u5728\u8a55\u4f30\u96c6\u5718\u7684siRNA\uff08\u5c0f\u5e72\u64feRNA\uff09\u5019\u9078\u85e5\u7269STP707\u7684\u5b89\u5168\u6027\u3001\u8010\u53d7\u6027\u548c\u6297\u816b\u7624\u6d3b\u6027\u3002\u8a72\u7814\u7a76\u62db\u52df\u4e86\u665a\u671f\u2571\u8f49\u79fb\u6027\u6216\u624b\u8853\u4e0d\u53ef\u5207\u9664\u7684\uff0c\u5c0d\u6a19\u6e96\u6cbb\u7642\u7121\u6548\u7684\u5be6\u9ad4\u7624\u60a3\u8005\uff0c\u5305\u62ec\u80f0\u817a\u764c\u3001\u7d50\u76f4\u8178\u764c\u3001\u809d\u764c\u3001\u9ed1\u8272\u7d20\u7624\u548c\u5176\u4ed6\u764c\u75c7\u60a3\u8005\u3002\u6211\u5011\u5728\u905e\u589e\u5291\u91cf\u4e2d\u63a2\u7d22\u4e86\u516d\u500b\u5291\u91cf\u6c34\u6e96\uff083mg\u30016mg\u300112mg\u300124mg\u300136mg\u548c48mg\uff09\u3002\u60a3\u8005\u572828\u5929\u9031\u671f\u4e2d\u7684\u7b2c1\u30018\u300115\u548c22\u5929\u63a5\u53d7\u975c\u8108\u8f38\u6ce8\u3002 \u8a72\u7814\u7a76\u62db\u52df\u4e8611\u540d\u80f0\u817a\u764c\u60a3\u8005\uff085\u540d\u7537\u6027\u548c6\u540d\u5973\u6027\uff0c\u5e73\u5747\u5e74\u9f6164\u6b72\uff09\u3002\u5728\u53c3\u52a0\u7814\u7a76\u4e4b\u524d\uff0c\u60a3\u8005\u5df2\u7d93\u63a5\u53d7\u4e86\u5927\u91cf\u6cbb\u7642\uff0c\u5728\u7d0d\u5165\u7814\u7a76\u4e4b\u524d\uff0c\u5e73\u5747\u63a5\u53d7\u4e86\u4e09\u7a2e\u6cbb\u7642\u65b9\u6cd5\uff08\u5305\u62ec\u5409\u897f\u4ed6\u6ff1\u3001\u7d2b\u6749\u9187\u548cFolfirinox\uff09\u3002\u521d\u6b65\u7d50\u679c\u8868\u660e\uff0c\u5b8c\u6210\u7684\u5e73\u5747\u6cbb\u7642\u9031\u671f\u70ba\u4e09\u500b\u9031\u671f\uff08\u5e73\u574712\u5291\uff09\u3002\u6240\u670911\u4f8b\u4f7f\u7528STP707\u85e5\u7269\u7684\u60a3\u8005\u75c5\u60c5\u7a69\u5b9a\u7684\u5e73\u5747\u5929\u6578\u70ba92\u5929\uff0c12mg\u7d44\u70ba31\u5929\uff0c24mg\u7d44\u70ba65\u5929\uff0c48mg\u7d44\u70ba112\u5929\uff0c\u5176\u4e2d1\u4f8b\u60a3\u8005\u75c5\u60c5\u7a69\u5b9a\u70ba281\u5929\u300211\u4f8b\u60a3\u8005\u672a\u5831\u544a\u6cbb\u7642\u76f8\u95dc\u4e0d\u826f\u4e8b\u4ef6\uff08TRAE\uff09\uff0c\u9664\u4e861\u4f8b\u60a3\u8005\u51fa\u73fe2\u7d1a\u8f38\u6ce8\u53cd\u61c9\u3002\u975e\u6cbb\u7642\u76f8\u95dc\u4e0d\u826f\u4e8b\u4ef6\u7e7c\u767c\u65bc\u5176\u665a\u671f\u8f49\u79fb\u6027\u75be\u75c5\uff0c\u5305\u62ec\u8178\u6897\u963b\u3001\u8179\u8139\u3001\u80c3\u8178\u9053\u6897\u963b\u3001\u6813\u585e\u3001\u6d88\u5316\u9053\u51fa\u8840\u3001\u816b\u7624\u75bc\u75db\u3001\u7f3a\u6c27\u548c\u547c\u5438\u56f0\u96e3\u3002 \u5373\u4f7f\u572848mg\u7684\u5291\u91cf\u6c34\u6e96\u4e0b\uff0c\u6240\u670950\u540d\u665a\u671f\u764c\u75c7\u60a3\u8005\u4ecd\u672a\u9054\u5230STP707\u6700\u5927\u8010\u53d7\u5291\u91cf\u3002STP707\u5728\u5df2\u7d93\u63a5\u53d7\u904e\u5927\u91cf\u6cbb\u7642\u7684\u764c\u75c7\u60a3\u8005\u7fa4\u9ad4\u4e2d\u8010\u53d7\u6027\u975e\u5e38\u597d\u300211\u540d\u80f0\u817a\u764c\u60a3\u8005\u5728\u4e0d\u540c\u5291\u91cf\u4e0b\u8868\u73fe\u51fa\u4f4e\u6bd2\u6027\u548c\u76f8\u5c0d\u7a69\u5b9a\u75be\u75c5\uff08106\u3001281\u548c302\u5929\uff09\uff0c\u9452\u65bcSTP707\u5728\u81e8\u5e8a\u524d\u8b49\u660e\u7684\u5c07T\u7d30\u80de\u52df\u96c6\u5230\u816b\u7624\u5fae\u74b0\u5883\uff08TME\uff09\u7684\u80fd\u529b\uff0c\u6211\u5011\u8a8d\u70ba\u6709\u5fc5\u8981\u55ae\u7368\u4f7f\u7528STP707\u6216\u8207\u514d\u75ab\u6aa2\u67e5\u9ede\u6291\u5236\u5291\u806f\u5408\u4f7f\u7528\u4ee5\u4f5c\u9032\u4e00\u6b65\u7814\u7a76\u3002\u9019\u662f\u57fa\u65bc\u591a\u80bd\u7d0d\u7c73\u9846\u7c92\u7684siRNA\u764c\u75c7\u6cbb\u7642\u85e5\u7269\u9996\u6b21\u5728\u6cbb\u7642\u665a\u671f\u80f0\u817a\u764c\u60a3\u8005\u65b9\u9762\u986f\u793a\u51fa\u65e9\u671f\u7a4d\u6975\u7684\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\u7d50\u679c\u3002 \u300c\u6211\u5011\u975e\u5e38\u9ad8\u8208\u5730\u770b\u5230STP707\uff0c\u6211\u5011\u9818\u5148\u7684siRNA\u85e5\u7269\u7522\u54c1\uff0c\u7528\u65bc\u6cbb\u7642\u5df2\u7d93\u63a5\u53d7\u904e\u5927\u91cf\u6cbb\u7642\u7684\u80f0\u817a\u764c\uff08\u6700\u81f4\u547d\u7684\u816b\u7624\u985e\u578b\u4e4b\u4e00\uff09\uff0c\u5728\u975c\u8108\u7d66\u85e5\u5f8c\u986f\u793a\u51fa\u9019\u4e9b\u5f37\u5927\u7684\u7d50\u679c\u3002\u5c0d\u65bc\u57fa\u65bcRNAi\u7684\u764c\u75c7\u7642\u6cd5\u6cbb\u7642\u8f49\u79fb\u6027\u816b\u7624\u4f86\u8aaa\uff0c\u9019\u662f\u4e00\u500b\u975e\u5e38\u6709\u524d\u666f\u7684\u7d50\u679c\u300d\uff0cSirnaomics\u5275\u59cb\u4eba\u3001\u8463\u4e8b\u6703\u4e3b\u5e2d\u3001\u57f7\u884c\u8463\u4e8b\u3001\u7e3d\u88c1\u517c\u9996\u5e2d\u57f7\u884c\u5b98\u9678\u967d\u535a\u58eb\u8aaa\u3002\u300c\u9019\u7a2e\u975c\u8108\u6ce8\u5c04\u7684STP707\u5236\u5291\u5177\u6709\u5f37\u5927\u7684\u5b89\u5168\u6027\u3001\u6301\u4e45\u7a69\u5b9a\u7684\u75be\u75c5\u7642\u6548\u548c\u5291\u91cf\u4f9d\u8cf4\u6027\u6297\u816b\u7624\u6d3b\u6027\uff0c\u7121\u8ad6\u662f\u4f5c\u70ba\u55ae\u4e00\u85e5\u7269\u9084\u662f\u8207\u514d\u75ab\u6aa2\u67e5\u9ede\u6291\u5236\u5291\u85e5\u7269\u806f\u5408\u4f7f\u7528\uff0c\u90fd\u662f\u4e00\u7a2e\u6f5b\u5728\u7684\u65b0\u578b\u764c\u75c7\u6cbb\u7642\u65b9\u6cd5\u3002\u300d \u5982\u6b32\u4e86\u89e3\u6709\u95dcSirnaomics\u81e8\u5e8a\u8a66\u9a57\u7684\u5176\u4ed6\u76f8\u95dc\u4fe1\u606f\uff0c\u8acb\u700f\u89bdClinicalTrials.gov\uff08\u8b58\u5225\u78bc\uff1aNCT05037149\uff09\uff0c\u548c\u516c\u53f8\u7db2\u7ad9www.sirnaomics.com\u3002 \u95dc\u65bcSTP707 STP707\u7531\u9776\u5411TGF-\u03b21\u548cCOX-2 mRNA\u7684\u5169\u500bsiRNA\u5be1\u6838\u7518\u9178\u7d44\u6210\uff0c\u4e26\u8207\u7d44\u6c28\u9178\u8cf4\u6c28\u9178\u5171\u805a\u80bd\uff08HKP+H\uff09\u7684\u8f09\u9ad4\u7d50\u5408\u914d\u88fd\u6210\u7d0d\u7c73\u9846\u7c92\u88fd\u5291\u3002\u9019\u7a2e\u7279\u5b9a\u7684\u591a\u80bd\u8f09\u9ad4\u8207STP705\u6240\u7528\u7684\u8f09\u9ad4\u4e0d\u540c\u3002\u6bcf\u500b\u55ae\u7368\u7684siRNA\u90fd\u5177\u5099\u6291\u5236\u76f8\u61c9\u9776\u9edemRNA\u8868\u9054\u7684\u80fd\u529b\u3002\u800cSTP707\u53ef\u540c\u6642\u6291\u5236TGF-\u03b21\u548cCOX-2\u7684\u8868\u9054\uff0c\u5f9e\u800c\u7522\u751f\u5354\u540c\u6548\u61c9\uff0c\u6e1b\u5c11\u708e\u75c7\u53cd\u61c9\u3002\u4e14TGF-\u03b21\u548cCOX-2\u7684\u904e\u5ea6\u8868\u9054\u5df2\u88ab\u8b49\u5be6\u5728\u816b\u7624\u5f62\u6210\u4e2d\u8d77\u8457\u95dc\u9375\u7684\u8abf\u7bc0\u4f5c\u7528\u3002\u5728STP707\u7684\u4e00\u9805\u81e8\u5e8a\u524d\u7814\u7a76\u4e2d\uff0c\u975c\u8108\u6ce8\u5c04\u7d66\u85e5\u5f8c\u53ef\u89c0\u5bdf\u5230\u5305\u62ec\u809d\u81df\u3001\u80ba\u548c\u7570\u7a2e\u79fb\u690d\u7624\u7b49\u5668\u5b98\u4e2d\u7684TGF-\u03b21\u548cCOX-2\u57fa\u56e0\u8868\u9054\u88ab\u6572\u4f4e\u3002\u6b64\u5916\uff0c\u5728\u591a\u500b\u81e8\u5e8a\u524d\u6a21\u578b\u4e2d\uff0cSTP707\u986f\u793a\u51fa\u5c0d\u591a\u7a2e\u5be6\u9ad4\u816b\u7624\u985e\u578b\u5f37\u5927\u7684\u6297\u816b\u7624\u6d3b\u6027\u3002\u5728\u5c0f\u9f20\u539f\u4f4d\u809d\u764c\u6a21\u578b\u4e2d\uff0cSTP707\u548c\u514d\u75ab\u6aa2\u67e5\u9ede\u6297\u9ad4\u806f\u7528\uff0c\u5177\u6709\u5354\u540c\u7684\u6297\u816b\u7624\u6d3b\u6027\u3002 \u95dc\u65bcSirnaomics Sirnaomics\u662f\u4e00\u5bb6RNA\u7642\u6cd5\u751f\u7269\u88fd\u85e5\u516c\u53f8\uff0c\u516c\u53f8\u5019\u9078\u7522\u54c1\u8655\u65bc\u81e8\u5e8a\u53ca\u81e8\u5e8a\u524d\u968e\u6bb5\uff0c\u5c08\u6ce8\u65bc\u63a2\u7d22\u53ca\u958b\u767c\u5275\u65b0\u85e5\u7269\uff0c\u7528\u65bc\u6cbb\u7642\u5177\u6709\u91ab\u7642\u9700\u6c42\u53ca\u9f90\u5927\u5e02\u5834\u6a5f\u6703\u7684\u9069\u61c9\u75c7\u3002Sirnaomics\u662f\u9996\u5bb6\u65bc\u4e9e\u6d32\u548c\u7f8e\u570b\u5747\u64c1\u6709\u91cd\u8981\u5e02\u5834\u5730\u4f4d\u7684\u81e8\u5e8a\u968e\u6bb5RNA\u7642\u6cd5\u751f\u7269\u88fd\u85e5\u516c\u53f8\u3002\u6191\u85c9\u5176\u5c08\u6709\u7684\u905e\u9001\u6280\u8853\uff1a\u591a\u80bd\u7d0d\u7c73\u9846\u7c92\u905e\u9001\u5e73\u53f0\u548c\u7b2c\u4e8c\u4ee3GalNAc\u5076\u806f\u7269\u905e\u9001\u5e73\u53f0\uff0c\u672c\u96c6\u5718\u5df2\u5efa\u7acb\u975e\u5e38\u8c50\u5bcc\u7684\u5019\u9078\u85e5\u7269\u7ba1\u7dda\u3002\u96a8\u8457\u516c\u53f8STP705\u548cSTP707\u7684\u81e8\u5e8a\u9805\u76ee\u53d6\u5f97\u591a\u9805\u6210\u529f\uff0cSirnaomics\u76ee\u524d\u5728\u63a8\u9032\u816b\u7624\u6cbb\u7642\u7684RNAi\u85e5\u7269\u65b9\u9762\u8655\u65bc\u570b\u969b\u9818\u5148\u5730\u4f4d\u3002STP122G\u662f\u9996\u6b3e\u9032\u5165\u81e8\u5e8a\u7814\u767c\u968e\u6bb5\u7684GalAhead\u2122\u6280\u8853\u5019\u9078\u85e5\u7269\u3002\u96a8\u8457Sirnaomics\u81e8\u5e8a\u751f\u7522\u8a2d\u65bd\u7684\u5efa\u7acb\uff0c\u672c\u96c6\u5718\u76ee\u524d\u6b63\u5728\u5be6\u73fe\u5f9e\u751f\u7269\u79d1\u6280\u516c\u53f8\u5411\u751f\u7269\u88fd\u85e5\u516c\u53f8\u7684\u8e8d\u9032\u3002\u5982\u6b32\u4e86\u89e3\u66f4\u591a\u95dc\u65bc\u516c\u53f8\u8cc7\u8a0a\uff0c\u53ef\u700f\u89bd\uff1awww.sirnaomics.com\u3002 \u00a0\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.franchise.com.hk\/en\/sirnaomics%e5%ae%a3%e4%bd%88%e5%ae%8c%e6%88%90stp707%e7%9a%84i%e6%9c%9f%e8%87%a8%e5%ba%8a%e7%a0%94%e7%a9%b6-%e5%85%b6%e7%b5%90%e6%9e%9c%e5%85%b7%e6%9c%89%e8%bc%83%e5%bc%b7%e7%9a%84%e5%ae%89%e5%85%a8\/20099\" \/>\n<meta property=\"og:site_name\" content=\"\u9999\u6e2f\u7279\u8a31\u7d93\u71df\" \/>\n<meta property=\"article:published_time\" content=\"2024-06-27T20:48:00+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/www.franchise.com.hk\/en\/sirnaomics%e5%ae%a3%e4%bd%88%e5%ae%8c%e6%88%90stp707%e7%9a%84i%e6%9c%9f%e8%87%a8%e5%ba%8a%e7%a0%94%e7%a9%b6-%e5%85%b6%e7%b5%90%e6%9e%9c%e5%85%b7%e6%9c%89%e8%bc%83%e5%bc%b7%e7%9a%84%e5%ae%89%e5%85%a8\/20099#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.franchise.com.hk\/en\/sirnaomics%e5%ae%a3%e4%bd%88%e5%ae%8c%e6%88%90stp707%e7%9a%84i%e6%9c%9f%e8%87%a8%e5%ba%8a%e7%a0%94%e7%a9%b6-%e5%85%b6%e7%b5%90%e6%9e%9c%e5%85%b7%e6%9c%89%e8%bc%83%e5%bc%b7%e7%9a%84%e5%ae%89%e5%85%a8\/20099\"},\"author\":{\"name\":\"\",\"@id\":\"\"},\"headline\":\"Sirnaomics\u5ba3\u4f48\u5b8c\u6210STP707\u7684I\u671f\u81e8\u5e8a\u7814\u7a76 \u5176\u7d50\u679c\u5177\u6709\u8f03\u5f37\u7684\u5b89\u5168\u6027\u548c\u6cbb\u7642\u80f0\u817a\u764c\u60a3\u8005\u7a69\u5b9a\u7684\u75be\u75c5\u6d3b\u6027\",\"datePublished\":\"2024-06-27T20:48:00+00:00\",\"dateModified\":\"2024-06-27T20:48:00+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.franchise.com.hk\/en\/sirnaomics%e5%ae%a3%e4%bd%88%e5%ae%8c%e6%88%90stp707%e7%9a%84i%e6%9c%9f%e8%87%a8%e5%ba%8a%e7%a0%94%e7%a9%b6-%e5%85%b6%e7%b5%90%e6%9e%9c%e5%85%b7%e6%9c%89%e8%bc%83%e5%bc%b7%e7%9a%84%e5%ae%89%e5%85%a8\/20099\"},\"wordCount\":86,\"publisher\":{\"@id\":\"https:\/\/www.franchise.com.hk\/en#organization\"},\"articleSection\":[\"\u672a\u5206\u985e\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.franchise.com.hk\/en\/sirnaomics%e5%ae%a3%e4%bd%88%e5%ae%8c%e6%88%90stp707%e7%9a%84i%e6%9c%9f%e8%87%a8%e5%ba%8a%e7%a0%94%e7%a9%b6-%e5%85%b6%e7%b5%90%e6%9e%9c%e5%85%b7%e6%9c%89%e8%bc%83%e5%bc%b7%e7%9a%84%e5%ae%89%e5%85%a8\/20099\",\"url\":\"https:\/\/www.franchise.com.hk\/en\/sirnaomics%e5%ae%a3%e4%bd%88%e5%ae%8c%e6%88%90stp707%e7%9a%84i%e6%9c%9f%e8%87%a8%e5%ba%8a%e7%a0%94%e7%a9%b6-%e5%85%b6%e7%b5%90%e6%9e%9c%e5%85%b7%e6%9c%89%e8%bc%83%e5%bc%b7%e7%9a%84%e5%ae%89%e5%85%a8\/20099\",\"name\":\"Sirnaomics\u5ba3\u4f48\u5b8c\u6210STP707\u7684I\u671f\u81e8\u5e8a\u7814\u7a76 \u5176\u7d50\u679c\u5177\u6709\u8f03\u5f37\u7684\u5b89\u5168\u6027\u548c\u6cbb\u7642\u80f0\u817a\u764c\u60a3\u8005\u7a69\u5b9a\u7684\u75be\u75c5\u6d3b\u6027 - \u9999\u6e2f\u7279\u8a31\u7d93\u71df\",\"isPartOf\":{\"@id\":\"https:\/\/www.franchise.com.hk\/en#website\"},\"datePublished\":\"2024-06-27T20:48:00+00:00\",\"dateModified\":\"2024-06-27T20:48:00+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/www.franchise.com.hk\/en\/sirnaomics%e5%ae%a3%e4%bd%88%e5%ae%8c%e6%88%90stp707%e7%9a%84i%e6%9c%9f%e8%87%a8%e5%ba%8a%e7%a0%94%e7%a9%b6-%e5%85%b6%e7%b5%90%e6%9e%9c%e5%85%b7%e6%9c%89%e8%bc%83%e5%bc%b7%e7%9a%84%e5%ae%89%e5%85%a8\/20099#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.franchise.com.hk\/en\/sirnaomics%e5%ae%a3%e4%bd%88%e5%ae%8c%e6%88%90stp707%e7%9a%84i%e6%9c%9f%e8%87%a8%e5%ba%8a%e7%a0%94%e7%a9%b6-%e5%85%b6%e7%b5%90%e6%9e%9c%e5%85%b7%e6%9c%89%e8%bc%83%e5%bc%b7%e7%9a%84%e5%ae%89%e5%85%a8\/20099\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.franchise.com.hk\/en\/sirnaomics%e5%ae%a3%e4%bd%88%e5%ae%8c%e6%88%90stp707%e7%9a%84i%e6%9c%9f%e8%87%a8%e5%ba%8a%e7%a0%94%e7%a9%b6-%e5%85%b6%e7%b5%90%e6%9e%9c%e5%85%b7%e6%9c%89%e8%bc%83%e5%bc%b7%e7%9a%84%e5%ae%89%e5%85%a8\/20099#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"\u9996\u9801\",\"item\":\"https:\/\/www.franchise.com.hk\/en\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Sirnaomics\u5ba3\u4f48\u5b8c\u6210STP707\u7684I\u671f\u81e8\u5e8a\u7814\u7a76 \u5176\u7d50\u679c\u5177\u6709\u8f03\u5f37\u7684\u5b89\u5168\u6027\u548c\u6cbb\u7642\u80f0\u817a\u764c\u60a3\u8005\u7a69\u5b9a\u7684\u75be\u75c5\u6d3b\u6027\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.franchise.com.hk\/en#website\",\"url\":\"https:\/\/www.franchise.com.hk\/en\",\"name\":\"\u9999\u6e2f\u7279\u8a31\u7d93\u71df\",\"description\":\"\u9999\u6e2f\u7279\u8a31\u7d93\u71df | Franchise HK\",\"publisher\":{\"@id\":\"https:\/\/www.franchise.com.hk\/en#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.franchise.com.hk\/en?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.franchise.com.hk\/en#organization\",\"name\":\"\u9999\u6e2f\u7279\u8a31\u7d93\u71df\",\"url\":\"https:\/\/www.franchise.com.hk\/en\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.franchise.com.hk\/en#\/schema\/logo\/image\/\",\"url\":\"https:\/\/i0.wp.com\/www.franchise.com.hk\/wp-content\/uploads\/2022\/05\/cropped-cropped-franchise-logo-02-e1652686851566-2.png?fit=350%2C76&ssl=1\",\"contentUrl\":\"https:\/\/i0.wp.com\/www.franchise.com.hk\/wp-content\/uploads\/2022\/05\/cropped-cropped-franchise-logo-02-e1652686851566-2.png?fit=350%2C76&ssl=1\",\"width\":350,\"height\":76,\"caption\":\"\u9999\u6e2f\u7279\u8a31\u7d93\u71df\"},\"image\":{\"@id\":\"https:\/\/www.franchise.com.hk\/en#\/schema\/logo\/image\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Sirnaomics\u5ba3\u4f48\u5b8c\u6210STP707\u7684I\u671f\u81e8\u5e8a\u7814\u7a76 \u5176\u7d50\u679c\u5177\u6709\u8f03\u5f37\u7684\u5b89\u5168\u6027\u548c\u6cbb\u7642\u80f0\u817a\u764c\u60a3\u8005\u7a69\u5b9a\u7684\u75be\u75c5\u6d3b\u6027 - \u9999\u6e2f\u7279\u8a31\u7d93\u71df","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.franchise.com.hk\/en\/sirnaomics%e5%ae%a3%e4%bd%88%e5%ae%8c%e6%88%90stp707%e7%9a%84i%e6%9c%9f%e8%87%a8%e5%ba%8a%e7%a0%94%e7%a9%b6-%e5%85%b6%e7%b5%90%e6%9e%9c%e5%85%b7%e6%9c%89%e8%bc%83%e5%bc%b7%e7%9a%84%e5%ae%89%e5%85%a8\/20099","og_locale":"en_US","og_type":"article","og_title":"Sirnaomics\u5ba3\u4f48\u5b8c\u6210STP707\u7684I\u671f\u81e8\u5e8a\u7814\u7a76 \u5176\u7d50\u679c\u5177\u6709\u8f03\u5f37\u7684\u5b89\u5168\u6027\u548c\u6cbb\u7642\u80f0\u817a\u764c\u60a3\u8005\u7a69\u5b9a\u7684\u75be\u75c5\u6d3b\u6027 - \u9999\u6e2f\u7279\u8a31\u7d93\u71df","og_description":"\u9999\u6e2f\u7279\u5225\u884c\u653f\u5340\u3001\u7f8e\u570b\u99ac\u91cc\u862d\u5dde\u5fb7\u570b\u57ce\u548c\u4e2d\u570b\u8607\u5dde2024\u5e746\u670828\u65e5 \/\u7f8e\u901a\u793e\/ &#8212; Sirnaomics Ltd.\uff08\u300c\u516c\u53f8\u300d\uff0c\u9023\u540c\u5176\u9644\u5c6c\u516c\u53f8\uff0c\u7d71\u7a31\u300c\u96c6\u5718\u300d\u6216\u300cSirnaomics\u300d\uff1b\u80a1\u4efd\u4ee3\u865f\uff1a2257\uff09\uff0c\u4e00\u5bb6\u884c\u696d\u9818\u5148\u7684\u5c08\u6ce8\u65bc\u63a2\u7d22\u53ca\u958b\u767cRNAi\u7642\u6cd5\u7684\u751f\u7269\u88fd\u85e5\u516c\u53f8\uff0c\u4eca\u65e5\u5ba3\u4f48\uff0c\u96c6\u5718\u5df2\u5b8c\u6210STP707\u7684I\u671f\u81e8\u5e8a\u7814\u7a76\uff0c\u5177\u6709\u8f03\u5f37\u7684\u5b89\u5168\u6027\u548c\u6cbb\u7642\u80f0\u817a\u764c\u60a3\u8005\u7a69\u5b9a\u7684\u75be\u75c5\u6d3b\u6027\u3002\u9019\u662f\u4e00\u9805\u5728\u7f8e\u570b11\u5bb6\u816b\u7624\u8a3a\u6240\u9032\u884c\u7684\u5291\u91cf\u905e\u589e\u7814\u7a76\u3002\u8a72\u7814\u7a76\u6d89\u53ca\u516d\u7d44\uff0c\u5305\u62ec50\u540d\u60a3\u6709\u5404\u7a2e\u764c\u75c7\u7684\u60a3\u8005\uff0c\u5176\u4e2d11\u540d\u60a3\u6709\u80f0\u817a\u764c\u3002 \u5728\u516c\u53f8\u5148\u524d\u65bc2023\u5e748\u6708\u767c\u4f48\u7684\u65b0\u805e\u7a3f\u4e2d\uff0c\u96c6\u5718\u6307\u51fa\u5176STP707\u6cbb\u7642\u591a\u767c\u6027\u5be6\u9ad4\u7624\u7684I\u671f\u7814\u7a76\u5df2\u5b8c\u6210\u6240\u6709\u7d66\u85e5\u65b9\u6848\u3002\u9019\u662f\u4e00\u9805\u62db\u52df\u4e86\u5c0d\u591a\u8f2a\u6cbb\u7642\u5931\u6557\u7684\u591a\u985e\u578b\u665a\u671f\u764c\u75c7\u60a3\u8005\u7684\u7c43\u5f0f\u7814\u7a76\u3002\u901a\u904e\u516d\u500b\u7d44\u7684\u905e\u589e\u5291\u91cf\u975c\u8108\u6ce8\u5c04\uff08IV\uff09\uff0c\u8a72\u7814\u7a76\u65e8\u5728\u8a55\u4f30\u96c6\u5718\u7684siRNA\uff08\u5c0f\u5e72\u64feRNA\uff09\u5019\u9078\u85e5\u7269STP707\u7684\u5b89\u5168\u6027\u3001\u8010\u53d7\u6027\u548c\u6297\u816b\u7624\u6d3b\u6027\u3002\u8a72\u7814\u7a76\u62db\u52df\u4e86\u665a\u671f\u2571\u8f49\u79fb\u6027\u6216\u624b\u8853\u4e0d\u53ef\u5207\u9664\u7684\uff0c\u5c0d\u6a19\u6e96\u6cbb\u7642\u7121\u6548\u7684\u5be6\u9ad4\u7624\u60a3\u8005\uff0c\u5305\u62ec\u80f0\u817a\u764c\u3001\u7d50\u76f4\u8178\u764c\u3001\u809d\u764c\u3001\u9ed1\u8272\u7d20\u7624\u548c\u5176\u4ed6\u764c\u75c7\u60a3\u8005\u3002\u6211\u5011\u5728\u905e\u589e\u5291\u91cf\u4e2d\u63a2\u7d22\u4e86\u516d\u500b\u5291\u91cf\u6c34\u6e96\uff083mg\u30016mg\u300112mg\u300124mg\u300136mg\u548c48mg\uff09\u3002\u60a3\u8005\u572828\u5929\u9031\u671f\u4e2d\u7684\u7b2c1\u30018\u300115\u548c22\u5929\u63a5\u53d7\u975c\u8108\u8f38\u6ce8\u3002 \u8a72\u7814\u7a76\u62db\u52df\u4e8611\u540d\u80f0\u817a\u764c\u60a3\u8005\uff085\u540d\u7537\u6027\u548c6\u540d\u5973\u6027\uff0c\u5e73\u5747\u5e74\u9f6164\u6b72\uff09\u3002\u5728\u53c3\u52a0\u7814\u7a76\u4e4b\u524d\uff0c\u60a3\u8005\u5df2\u7d93\u63a5\u53d7\u4e86\u5927\u91cf\u6cbb\u7642\uff0c\u5728\u7d0d\u5165\u7814\u7a76\u4e4b\u524d\uff0c\u5e73\u5747\u63a5\u53d7\u4e86\u4e09\u7a2e\u6cbb\u7642\u65b9\u6cd5\uff08\u5305\u62ec\u5409\u897f\u4ed6\u6ff1\u3001\u7d2b\u6749\u9187\u548cFolfirinox\uff09\u3002\u521d\u6b65\u7d50\u679c\u8868\u660e\uff0c\u5b8c\u6210\u7684\u5e73\u5747\u6cbb\u7642\u9031\u671f\u70ba\u4e09\u500b\u9031\u671f\uff08\u5e73\u574712\u5291\uff09\u3002\u6240\u670911\u4f8b\u4f7f\u7528STP707\u85e5\u7269\u7684\u60a3\u8005\u75c5\u60c5\u7a69\u5b9a\u7684\u5e73\u5747\u5929\u6578\u70ba92\u5929\uff0c12mg\u7d44\u70ba31\u5929\uff0c24mg\u7d44\u70ba65\u5929\uff0c48mg\u7d44\u70ba112\u5929\uff0c\u5176\u4e2d1\u4f8b\u60a3\u8005\u75c5\u60c5\u7a69\u5b9a\u70ba281\u5929\u300211\u4f8b\u60a3\u8005\u672a\u5831\u544a\u6cbb\u7642\u76f8\u95dc\u4e0d\u826f\u4e8b\u4ef6\uff08TRAE\uff09\uff0c\u9664\u4e861\u4f8b\u60a3\u8005\u51fa\u73fe2\u7d1a\u8f38\u6ce8\u53cd\u61c9\u3002\u975e\u6cbb\u7642\u76f8\u95dc\u4e0d\u826f\u4e8b\u4ef6\u7e7c\u767c\u65bc\u5176\u665a\u671f\u8f49\u79fb\u6027\u75be\u75c5\uff0c\u5305\u62ec\u8178\u6897\u963b\u3001\u8179\u8139\u3001\u80c3\u8178\u9053\u6897\u963b\u3001\u6813\u585e\u3001\u6d88\u5316\u9053\u51fa\u8840\u3001\u816b\u7624\u75bc\u75db\u3001\u7f3a\u6c27\u548c\u547c\u5438\u56f0\u96e3\u3002 \u5373\u4f7f\u572848mg\u7684\u5291\u91cf\u6c34\u6e96\u4e0b\uff0c\u6240\u670950\u540d\u665a\u671f\u764c\u75c7\u60a3\u8005\u4ecd\u672a\u9054\u5230STP707\u6700\u5927\u8010\u53d7\u5291\u91cf\u3002STP707\u5728\u5df2\u7d93\u63a5\u53d7\u904e\u5927\u91cf\u6cbb\u7642\u7684\u764c\u75c7\u60a3\u8005\u7fa4\u9ad4\u4e2d\u8010\u53d7\u6027\u975e\u5e38\u597d\u300211\u540d\u80f0\u817a\u764c\u60a3\u8005\u5728\u4e0d\u540c\u5291\u91cf\u4e0b\u8868\u73fe\u51fa\u4f4e\u6bd2\u6027\u548c\u76f8\u5c0d\u7a69\u5b9a\u75be\u75c5\uff08106\u3001281\u548c302\u5929\uff09\uff0c\u9452\u65bcSTP707\u5728\u81e8\u5e8a\u524d\u8b49\u660e\u7684\u5c07T\u7d30\u80de\u52df\u96c6\u5230\u816b\u7624\u5fae\u74b0\u5883\uff08TME\uff09\u7684\u80fd\u529b\uff0c\u6211\u5011\u8a8d\u70ba\u6709\u5fc5\u8981\u55ae\u7368\u4f7f\u7528STP707\u6216\u8207\u514d\u75ab\u6aa2\u67e5\u9ede\u6291\u5236\u5291\u806f\u5408\u4f7f\u7528\u4ee5\u4f5c\u9032\u4e00\u6b65\u7814\u7a76\u3002\u9019\u662f\u57fa\u65bc\u591a\u80bd\u7d0d\u7c73\u9846\u7c92\u7684siRNA\u764c\u75c7\u6cbb\u7642\u85e5\u7269\u9996\u6b21\u5728\u6cbb\u7642\u665a\u671f\u80f0\u817a\u764c\u60a3\u8005\u65b9\u9762\u986f\u793a\u51fa\u65e9\u671f\u7a4d\u6975\u7684\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\u7d50\u679c\u3002 \u300c\u6211\u5011\u975e\u5e38\u9ad8\u8208\u5730\u770b\u5230STP707\uff0c\u6211\u5011\u9818\u5148\u7684siRNA\u85e5\u7269\u7522\u54c1\uff0c\u7528\u65bc\u6cbb\u7642\u5df2\u7d93\u63a5\u53d7\u904e\u5927\u91cf\u6cbb\u7642\u7684\u80f0\u817a\u764c\uff08\u6700\u81f4\u547d\u7684\u816b\u7624\u985e\u578b\u4e4b\u4e00\uff09\uff0c\u5728\u975c\u8108\u7d66\u85e5\u5f8c\u986f\u793a\u51fa\u9019\u4e9b\u5f37\u5927\u7684\u7d50\u679c\u3002\u5c0d\u65bc\u57fa\u65bcRNAi\u7684\u764c\u75c7\u7642\u6cd5\u6cbb\u7642\u8f49\u79fb\u6027\u816b\u7624\u4f86\u8aaa\uff0c\u9019\u662f\u4e00\u500b\u975e\u5e38\u6709\u524d\u666f\u7684\u7d50\u679c\u300d\uff0cSirnaomics\u5275\u59cb\u4eba\u3001\u8463\u4e8b\u6703\u4e3b\u5e2d\u3001\u57f7\u884c\u8463\u4e8b\u3001\u7e3d\u88c1\u517c\u9996\u5e2d\u57f7\u884c\u5b98\u9678\u967d\u535a\u58eb\u8aaa\u3002\u300c\u9019\u7a2e\u975c\u8108\u6ce8\u5c04\u7684STP707\u5236\u5291\u5177\u6709\u5f37\u5927\u7684\u5b89\u5168\u6027\u3001\u6301\u4e45\u7a69\u5b9a\u7684\u75be\u75c5\u7642\u6548\u548c\u5291\u91cf\u4f9d\u8cf4\u6027\u6297\u816b\u7624\u6d3b\u6027\uff0c\u7121\u8ad6\u662f\u4f5c\u70ba\u55ae\u4e00\u85e5\u7269\u9084\u662f\u8207\u514d\u75ab\u6aa2\u67e5\u9ede\u6291\u5236\u5291\u85e5\u7269\u806f\u5408\u4f7f\u7528\uff0c\u90fd\u662f\u4e00\u7a2e\u6f5b\u5728\u7684\u65b0\u578b\u764c\u75c7\u6cbb\u7642\u65b9\u6cd5\u3002\u300d \u5982\u6b32\u4e86\u89e3\u6709\u95dcSirnaomics\u81e8\u5e8a\u8a66\u9a57\u7684\u5176\u4ed6\u76f8\u95dc\u4fe1\u606f\uff0c\u8acb\u700f\u89bdClinicalTrials.gov\uff08\u8b58\u5225\u78bc\uff1aNCT05037149\uff09\uff0c\u548c\u516c\u53f8\u7db2\u7ad9www.sirnaomics.com\u3002 \u95dc\u65bcSTP707 STP707\u7531\u9776\u5411TGF-\u03b21\u548cCOX-2 mRNA\u7684\u5169\u500bsiRNA\u5be1\u6838\u7518\u9178\u7d44\u6210\uff0c\u4e26\u8207\u7d44\u6c28\u9178\u8cf4\u6c28\u9178\u5171\u805a\u80bd\uff08HKP+H\uff09\u7684\u8f09\u9ad4\u7d50\u5408\u914d\u88fd\u6210\u7d0d\u7c73\u9846\u7c92\u88fd\u5291\u3002\u9019\u7a2e\u7279\u5b9a\u7684\u591a\u80bd\u8f09\u9ad4\u8207STP705\u6240\u7528\u7684\u8f09\u9ad4\u4e0d\u540c\u3002\u6bcf\u500b\u55ae\u7368\u7684siRNA\u90fd\u5177\u5099\u6291\u5236\u76f8\u61c9\u9776\u9edemRNA\u8868\u9054\u7684\u80fd\u529b\u3002\u800cSTP707\u53ef\u540c\u6642\u6291\u5236TGF-\u03b21\u548cCOX-2\u7684\u8868\u9054\uff0c\u5f9e\u800c\u7522\u751f\u5354\u540c\u6548\u61c9\uff0c\u6e1b\u5c11\u708e\u75c7\u53cd\u61c9\u3002\u4e14TGF-\u03b21\u548cCOX-2\u7684\u904e\u5ea6\u8868\u9054\u5df2\u88ab\u8b49\u5be6\u5728\u816b\u7624\u5f62\u6210\u4e2d\u8d77\u8457\u95dc\u9375\u7684\u8abf\u7bc0\u4f5c\u7528\u3002\u5728STP707\u7684\u4e00\u9805\u81e8\u5e8a\u524d\u7814\u7a76\u4e2d\uff0c\u975c\u8108\u6ce8\u5c04\u7d66\u85e5\u5f8c\u53ef\u89c0\u5bdf\u5230\u5305\u62ec\u809d\u81df\u3001\u80ba\u548c\u7570\u7a2e\u79fb\u690d\u7624\u7b49\u5668\u5b98\u4e2d\u7684TGF-\u03b21\u548cCOX-2\u57fa\u56e0\u8868\u9054\u88ab\u6572\u4f4e\u3002\u6b64\u5916\uff0c\u5728\u591a\u500b\u81e8\u5e8a\u524d\u6a21\u578b\u4e2d\uff0cSTP707\u986f\u793a\u51fa\u5c0d\u591a\u7a2e\u5be6\u9ad4\u816b\u7624\u985e\u578b\u5f37\u5927\u7684\u6297\u816b\u7624\u6d3b\u6027\u3002\u5728\u5c0f\u9f20\u539f\u4f4d\u809d\u764c\u6a21\u578b\u4e2d\uff0cSTP707\u548c\u514d\u75ab\u6aa2\u67e5\u9ede\u6297\u9ad4\u806f\u7528\uff0c\u5177\u6709\u5354\u540c\u7684\u6297\u816b\u7624\u6d3b\u6027\u3002 \u95dc\u65bcSirnaomics Sirnaomics\u662f\u4e00\u5bb6RNA\u7642\u6cd5\u751f\u7269\u88fd\u85e5\u516c\u53f8\uff0c\u516c\u53f8\u5019\u9078\u7522\u54c1\u8655\u65bc\u81e8\u5e8a\u53ca\u81e8\u5e8a\u524d\u968e\u6bb5\uff0c\u5c08\u6ce8\u65bc\u63a2\u7d22\u53ca\u958b\u767c\u5275\u65b0\u85e5\u7269\uff0c\u7528\u65bc\u6cbb\u7642\u5177\u6709\u91ab\u7642\u9700\u6c42\u53ca\u9f90\u5927\u5e02\u5834\u6a5f\u6703\u7684\u9069\u61c9\u75c7\u3002Sirnaomics\u662f\u9996\u5bb6\u65bc\u4e9e\u6d32\u548c\u7f8e\u570b\u5747\u64c1\u6709\u91cd\u8981\u5e02\u5834\u5730\u4f4d\u7684\u81e8\u5e8a\u968e\u6bb5RNA\u7642\u6cd5\u751f\u7269\u88fd\u85e5\u516c\u53f8\u3002\u6191\u85c9\u5176\u5c08\u6709\u7684\u905e\u9001\u6280\u8853\uff1a\u591a\u80bd\u7d0d\u7c73\u9846\u7c92\u905e\u9001\u5e73\u53f0\u548c\u7b2c\u4e8c\u4ee3GalNAc\u5076\u806f\u7269\u905e\u9001\u5e73\u53f0\uff0c\u672c\u96c6\u5718\u5df2\u5efa\u7acb\u975e\u5e38\u8c50\u5bcc\u7684\u5019\u9078\u85e5\u7269\u7ba1\u7dda\u3002\u96a8\u8457\u516c\u53f8STP705\u548cSTP707\u7684\u81e8\u5e8a\u9805\u76ee\u53d6\u5f97\u591a\u9805\u6210\u529f\uff0cSirnaomics\u76ee\u524d\u5728\u63a8\u9032\u816b\u7624\u6cbb\u7642\u7684RNAi\u85e5\u7269\u65b9\u9762\u8655\u65bc\u570b\u969b\u9818\u5148\u5730\u4f4d\u3002STP122G\u662f\u9996\u6b3e\u9032\u5165\u81e8\u5e8a\u7814\u767c\u968e\u6bb5\u7684GalAhead\u2122\u6280\u8853\u5019\u9078\u85e5\u7269\u3002\u96a8\u8457Sirnaomics\u81e8\u5e8a\u751f\u7522\u8a2d\u65bd\u7684\u5efa\u7acb\uff0c\u672c\u96c6\u5718\u76ee\u524d\u6b63\u5728\u5be6\u73fe\u5f9e\u751f\u7269\u79d1\u6280\u516c\u53f8\u5411\u751f\u7269\u88fd\u85e5\u516c\u53f8\u7684\u8e8d\u9032\u3002\u5982\u6b32\u4e86\u89e3\u66f4\u591a\u95dc\u65bc\u516c\u53f8\u8cc7\u8a0a\uff0c\u53ef\u700f\u89bd\uff1awww.sirnaomics.com\u3002 \u00a0","og_url":"https:\/\/www.franchise.com.hk\/en\/sirnaomics%e5%ae%a3%e4%bd%88%e5%ae%8c%e6%88%90stp707%e7%9a%84i%e6%9c%9f%e8%87%a8%e5%ba%8a%e7%a0%94%e7%a9%b6-%e5%85%b6%e7%b5%90%e6%9e%9c%e5%85%b7%e6%9c%89%e8%bc%83%e5%bc%b7%e7%9a%84%e5%ae%89%e5%85%a8\/20099","og_site_name":"\u9999\u6e2f\u7279\u8a31\u7d93\u71df","article_published_time":"2024-06-27T20:48:00+00:00","twitter_card":"summary_large_image","schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.franchise.com.hk\/en\/sirnaomics%e5%ae%a3%e4%bd%88%e5%ae%8c%e6%88%90stp707%e7%9a%84i%e6%9c%9f%e8%87%a8%e5%ba%8a%e7%a0%94%e7%a9%b6-%e5%85%b6%e7%b5%90%e6%9e%9c%e5%85%b7%e6%9c%89%e8%bc%83%e5%bc%b7%e7%9a%84%e5%ae%89%e5%85%a8\/20099#article","isPartOf":{"@id":"https:\/\/www.franchise.com.hk\/en\/sirnaomics%e5%ae%a3%e4%bd%88%e5%ae%8c%e6%88%90stp707%e7%9a%84i%e6%9c%9f%e8%87%a8%e5%ba%8a%e7%a0%94%e7%a9%b6-%e5%85%b6%e7%b5%90%e6%9e%9c%e5%85%b7%e6%9c%89%e8%bc%83%e5%bc%b7%e7%9a%84%e5%ae%89%e5%85%a8\/20099"},"author":{"name":"","@id":""},"headline":"Sirnaomics\u5ba3\u4f48\u5b8c\u6210STP707\u7684I\u671f\u81e8\u5e8a\u7814\u7a76 \u5176\u7d50\u679c\u5177\u6709\u8f03\u5f37\u7684\u5b89\u5168\u6027\u548c\u6cbb\u7642\u80f0\u817a\u764c\u60a3\u8005\u7a69\u5b9a\u7684\u75be\u75c5\u6d3b\u6027","datePublished":"2024-06-27T20:48:00+00:00","dateModified":"2024-06-27T20:48:00+00:00","mainEntityOfPage":{"@id":"https:\/\/www.franchise.com.hk\/en\/sirnaomics%e5%ae%a3%e4%bd%88%e5%ae%8c%e6%88%90stp707%e7%9a%84i%e6%9c%9f%e8%87%a8%e5%ba%8a%e7%a0%94%e7%a9%b6-%e5%85%b6%e7%b5%90%e6%9e%9c%e5%85%b7%e6%9c%89%e8%bc%83%e5%bc%b7%e7%9a%84%e5%ae%89%e5%85%a8\/20099"},"wordCount":86,"publisher":{"@id":"https:\/\/www.franchise.com.hk\/en#organization"},"articleSection":["\u672a\u5206\u985e"],"inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.franchise.com.hk\/en\/sirnaomics%e5%ae%a3%e4%bd%88%e5%ae%8c%e6%88%90stp707%e7%9a%84i%e6%9c%9f%e8%87%a8%e5%ba%8a%e7%a0%94%e7%a9%b6-%e5%85%b6%e7%b5%90%e6%9e%9c%e5%85%b7%e6%9c%89%e8%bc%83%e5%bc%b7%e7%9a%84%e5%ae%89%e5%85%a8\/20099","url":"https:\/\/www.franchise.com.hk\/en\/sirnaomics%e5%ae%a3%e4%bd%88%e5%ae%8c%e6%88%90stp707%e7%9a%84i%e6%9c%9f%e8%87%a8%e5%ba%8a%e7%a0%94%e7%a9%b6-%e5%85%b6%e7%b5%90%e6%9e%9c%e5%85%b7%e6%9c%89%e8%bc%83%e5%bc%b7%e7%9a%84%e5%ae%89%e5%85%a8\/20099","name":"Sirnaomics\u5ba3\u4f48\u5b8c\u6210STP707\u7684I\u671f\u81e8\u5e8a\u7814\u7a76 \u5176\u7d50\u679c\u5177\u6709\u8f03\u5f37\u7684\u5b89\u5168\u6027\u548c\u6cbb\u7642\u80f0\u817a\u764c\u60a3\u8005\u7a69\u5b9a\u7684\u75be\u75c5\u6d3b\u6027 - \u9999\u6e2f\u7279\u8a31\u7d93\u71df","isPartOf":{"@id":"https:\/\/www.franchise.com.hk\/en#website"},"datePublished":"2024-06-27T20:48:00+00:00","dateModified":"2024-06-27T20:48:00+00:00","breadcrumb":{"@id":"https:\/\/www.franchise.com.hk\/en\/sirnaomics%e5%ae%a3%e4%bd%88%e5%ae%8c%e6%88%90stp707%e7%9a%84i%e6%9c%9f%e8%87%a8%e5%ba%8a%e7%a0%94%e7%a9%b6-%e5%85%b6%e7%b5%90%e6%9e%9c%e5%85%b7%e6%9c%89%e8%bc%83%e5%bc%b7%e7%9a%84%e5%ae%89%e5%85%a8\/20099#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.franchise.com.hk\/en\/sirnaomics%e5%ae%a3%e4%bd%88%e5%ae%8c%e6%88%90stp707%e7%9a%84i%e6%9c%9f%e8%87%a8%e5%ba%8a%e7%a0%94%e7%a9%b6-%e5%85%b6%e7%b5%90%e6%9e%9c%e5%85%b7%e6%9c%89%e8%bc%83%e5%bc%b7%e7%9a%84%e5%ae%89%e5%85%a8\/20099"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/www.franchise.com.hk\/en\/sirnaomics%e5%ae%a3%e4%bd%88%e5%ae%8c%e6%88%90stp707%e7%9a%84i%e6%9c%9f%e8%87%a8%e5%ba%8a%e7%a0%94%e7%a9%b6-%e5%85%b6%e7%b5%90%e6%9e%9c%e5%85%b7%e6%9c%89%e8%bc%83%e5%bc%b7%e7%9a%84%e5%ae%89%e5%85%a8\/20099#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"\u9996\u9801","item":"https:\/\/www.franchise.com.hk\/en"},{"@type":"ListItem","position":2,"name":"Sirnaomics\u5ba3\u4f48\u5b8c\u6210STP707\u7684I\u671f\u81e8\u5e8a\u7814\u7a76 \u5176\u7d50\u679c\u5177\u6709\u8f03\u5f37\u7684\u5b89\u5168\u6027\u548c\u6cbb\u7642\u80f0\u817a\u764c\u60a3\u8005\u7a69\u5b9a\u7684\u75be\u75c5\u6d3b\u6027"}]},{"@type":"WebSite","@id":"https:\/\/www.franchise.com.hk\/en#website","url":"https:\/\/www.franchise.com.hk\/en","name":"\u9999\u6e2f\u7279\u8a31\u7d93\u71df","description":"\u9999\u6e2f\u7279\u8a31\u7d93\u71df | Franchise HK","publisher":{"@id":"https:\/\/www.franchise.com.hk\/en#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.franchise.com.hk\/en?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/www.franchise.com.hk\/en#organization","name":"\u9999\u6e2f\u7279\u8a31\u7d93\u71df","url":"https:\/\/www.franchise.com.hk\/en","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.franchise.com.hk\/en#\/schema\/logo\/image\/","url":"https:\/\/i0.wp.com\/www.franchise.com.hk\/wp-content\/uploads\/2022\/05\/cropped-cropped-franchise-logo-02-e1652686851566-2.png?fit=350%2C76&ssl=1","contentUrl":"https:\/\/i0.wp.com\/www.franchise.com.hk\/wp-content\/uploads\/2022\/05\/cropped-cropped-franchise-logo-02-e1652686851566-2.png?fit=350%2C76&ssl=1","width":350,"height":76,"caption":"\u9999\u6e2f\u7279\u8a31\u7d93\u71df"},"image":{"@id":"https:\/\/www.franchise.com.hk\/en#\/schema\/logo\/image\/"}}]}},"jetpack_featured_media_url":"","_links":{"self":[{"href":"https:\/\/www.franchise.com.hk\/en\/wp-json\/wp\/v2\/posts\/20099"}],"collection":[{"href":"https:\/\/www.franchise.com.hk\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.franchise.com.hk\/en\/wp-json\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/www.franchise.com.hk\/en\/wp-json\/wp\/v2\/comments?post=20099"}],"version-history":[{"count":0,"href":"https:\/\/www.franchise.com.hk\/en\/wp-json\/wp\/v2\/posts\/20099\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.franchise.com.hk\/en\/wp-json\/wp\/v2\/media?parent=20099"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.franchise.com.hk\/en\/wp-json\/wp\/v2\/categories?post=20099"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.franchise.com.hk\/en\/wp-json\/wp\/v2\/tags?post=20099"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}