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\/>\n\u64ce\u6a02\u00ae\uff1a2024\u5e74\u7b2c\u4e00\u5b63\u5ea6\u92b7\u552e\u6536\u5165\u70ba610\u842c\u7f8e\u5143\uff0c2023\u5e74\u540c\u671f\u70ba130\u842c\u7f8e\u5143\uff0c\u540c\u6bd4\u589e\u9577367%\uff0c\u4e3b\u8981\u662f\u7531\u65bc\u5176\u65bc2023\u5e74\u7b2c\u4e00\u5b63\u5ea6\u88ab\u7d0d\u5165NRDL\uff0c\u7528\u65bc\u665a\u671f\u56db\u7dda\u80c3\u8178\u9593\u8cea\u7624\uff08GIST\uff09\u7684\u6cbb\u7642\u3002<br \/>\n\u7d10\u518d\u6a02\u00ae\uff1a2024\u5e74\u7b2c\u4e00\u5b63\u5ea6\u92b7\u552e\u6536\u5165\u70ba990\u842c\u7f8e\u5143\uff0c2023\u5e74\u540c\u671f\u70ba550\u842c\u7f8e\u5143\uff0c\u540c\u6bd4\u589e\u957781%\uff0c\u4e3b\u8981\u662f\u7531\u65bc\u7d10\u518d\u6a02\u975c\u8108\u6ce8\u5c04\u5291\u578b\u65bc2023\u5e74\u7b2c\u4e00\u5b63\u5ea6\u88ab\u7d0d\u5165NRDL\uff0c\u7528\u65bc\u6cbb\u7642\u6210\u4eba\u793e\u5340\u7372\u5f97\u6027\u7d30\u83cc\u6027\u80ba\u708e (CABP) \u548c\u6025\u6027\u7d30\u83cc\u6027\u76ae\u819a\u548c\u76ae\u819a\u7d50\u69cb\u611f\u67d3 (ABSSSI)\uff0c2024\u5e74\u7b2c\u4e00\u5b63\u5ea6\u4e0a\u8ff0\u9069\u61c9\u8b49\u7684\u53e3\u670d\u5291\u578b\u88ab\u7d0d\u5165NRDL\u3002<br \/>\n   2024\u5e74\u7b2c\u4e00\u5b63\u5ea6\u7684\u7814\u767c\u958b\u652f\u70ba5,460\u842c\u7f8e\u5143\uff0c2023\u5e74\u540c\u671f\u70ba4,850\u842c\u7f8e\u5143\u3002\u9019\u4e00\u589e\u9577\u4e3b\u8981\u662f\u7531\u65bc\u65b0\u555f\u52d5\u548c\u6b63\u5728\u958b\u5c55\u7684\u81e8\u5e8a\u7814\u7a76\u7684\u8cbb\u7528\u7684\u589e\u52a0\uff0c\u90e8\u5206\u88ab\u8a31\u53ef\u7522\u54c1\u7684\u91cc\u7a0b\u7891\u6b3e\u9805\u7684\u6e1b\u5c11\u6240\u62b5\u92b7\u3002   2024\u5e74\u7b2c\u4e00\u5b63\u5ea6\u7684\u92b7\u552e\u3001\u4e00\u822c\u548c\u884c\u653f\u958b\u652f\u70ba6,920\u842c\u7f8e\u5143\uff0c2023\u5e74\u540c\u671f\u70ba6,250\u842c\u7f8e\u5143\u3002\u9019\u4e00\u589e\u9577\u4e3b\u8981\u662f\u7531\u65bc\u8207\u885b\u5049\u8fe6\u4e0a\u5e02\u6709\u95dc\u7684\u4e00\u822c\u92b7\u552e\u8cbb\u7528\u7684\u589e\u9577\u548c\u4eba\u54e1\u7684\u589e\u52a0\u3002   2024\u5e74\u7b2c\u4e00\u5b63\u5ea6\u8667\u640d\u6de8\u984d\u70ba5,350\u842c\u7f8e\u5143\uff0c\u6bcf\u80a1\u666e\u901a\u80a1\u8667\u640d0.05\u7f8e\u5143\uff08\u6bcf\u4efd\u7f8e\u570b\u5b58\u6258\u80a1\u4efd\uff08ADS\uff09\u8667\u640d\u70ba0.55\u7f8e\u5143\uff09\uff0c2023\u5e74\u540c\u671f\u8667\u640d\u6de8\u984d\u70ba4,910\u842c\u7f8e\u5143\u3002\u6bcf\u80a1\u666e\u901a\u80a1\u8667\u640d0.05\u7f8e\u5143\uff08\u6bcf\u4efdADS\u8667\u640d\u70ba0.51\u7f8e\u5143\uff09\u3002   \u622a\u81f32024\u5e743\u670831\u65e5\uff0c\u73fe\u91d1\u53ca\u73fe\u91d1\u7b49\u50f9\u7269\u3001\u77ed\u671f\u6295\u8cc7\u3001\u6d41\u52d5\u53d7\u9650\u5236\u73fe\u91d1\u7e3d\u8a08\u70ba7.508\u5104\u7f8e\u5143\uff0c\u622a\u81f32023\u5e7412\u670831\u65e5\u70ba8.065\u5104\u7f8e\u5143\u3002  <\/p>\n<p>\u516c\u53f8\u9032\u5c55<\/p>\n<p>2024\u5e744\u6708\uff0c\u6731\u5f64\u5148\u751f\u52a0\u5165\u518d\u9f0e\u91ab\u85e5\uff0c\u64d4\u4efb\u5927\u4e2d\u83ef\u53402\u9996\u5e2d\u5546\u52d9\u5b98\u3002\u6731\u5f64\u5148\u751f\u5728\u69cb\u5efa\u5275\u65b0\u5546\u696d\u6a21\u5f0f\u548c\u8cc7\u6e90\u6574\u5408\u65b9\u9762\u64c1\u6709\u8c50\u5bcc\u7684\u7d93\u9a57\uff0c\u5c07\u5e6b\u52a9\u6211\u5011\u9032\u4e00\u6b65\u52a0\u5f37\u5546\u696d\u5316\u904b\u71df\uff0c\u63a8\u52d5\u5927\u4e2d\u83ef\u5340\u7684\u92b7\u552e\u548c\u5229\u6f64\u589e\u9577\u3002\u5728\u52a0\u5165\u518d\u9f0e\u91ab\u85e5\u4e4b\u524d\uff0c\u4ed6\u5728\u5148\u8072\u518d\u660e\u4efb\u8077\uff0c\u6700\u8fd1\u7684\u8077\u4f4d\u70ba\u9996\u5e2d\u904b\u71df\u5b98\uff0c\u8ca0\u8cac\u71df\u92b7\u548c\u88fd\u85e5\u696d\u52d9\u3002\u5728\u6b64\u4e4b\u524d\uff0c\u4ed6\u66fe\u5728\u963f\u65af\u5229\u5eb7\u3001\u7f85\u6c0f\u3001\u8cfd\u8afe\u83f2\u548c\u767e\u6642\u7f8e\u65bd\u8cb4\u5bf6\uff08BMS\uff09\u7b49\u5168\u7403\u9818\u5148\u7684\u751f\u7269\u88fd\u85e5\u516c\u53f8\u64d4\u4efb\u904e\u591a\u500b\u904b\u71df\u3001\u92b7\u552e\u548c\u5e02\u5834\u71df\u92b7\u9818\u5c0e\u8077\u52d9\u3002  <\/p>\n<p>\u8fd1\u671f\u7ba1\u7dda\u4eae\u9ede<\/p>\n<p>\u81ea\u4e0a\u6b21\u8ca1\u5831\u767c\u4f48\u4ee5\u4f86\u518d\u9f0e\u91ab\u85e5\u4e3b\u8981\u7522\u54c1\u9032\u5c55\u5305\u62ec\uff1a<\/p>\n<p>\u816b\u7624\u9818\u57df\u7ba1\u7dda<\/p>\n<p>\u816b\u7624\u96fb\u5834\u6cbb\u7642\uff1a<br \/>\n2024\u5e743\u6708\uff0c\u518d\u9f0e\u91ab\u85e5\u5408\u4f5c\u5925\u4f34Novocure\u5ba3\u4f48\u91dd\u5c0d\u975e\u5c0f\u7d30\u80de\u80ba\u764c\uff08NSCLC\uff09\u8166\u8f49\u79fb\u76843\u671fMETIS\u81e8\u5e8a\u7814\u7a76\u53d6\u5f97\u967d\u6027\u7d50\u679c\u3002\u816b\u7624\u96fb\u5834\u6cbb\u7642\u806f\u5408\u652f\u6301\u7642\u6cd5\uff0c\u8207\u55ae\u7368\u63a5\u53d7\u652f\u6301\u7642\u6cd5\u76f8\u6bd4\uff0c\u4e2d\u4f4d\u81f3\u9871\u5167\u9032\u5c55\u6642\u9593\u986f\u8457\u6539\u5584\uff08\u5206\u5225\u70ba21.9\u500b\u6708\u548c11.3\u500b\u6708\uff09\u3002\u76f8\u95dc\u7d50\u679c\u5c07\u57286\u67083\u65e5\u5728\u829d\u52a0\u54e5\u8209\u884c\u76842024\u5e74\u7f8e\u570b\u81e8\u5e8a\u816b\u7624\u5b78\u6703\uff08ASCO\uff09\u5e74\u6703\u4e0a\u4f5c\u70ba\u5b8c\u6574\u53e3\u982d\u5831\u544a\uff08LBA\uff09\u767c\u4f48\u3002\u518d\u9f0e\u91ab\u85e5\u6b63\u5728\u5927\u4e2d\u83ef\u5340\u53c3\u52a0METIS\u7814\u7a76\u3002    <\/p>\n<p>Bemarituzumab (FGFR2b):\u00a0<br \/>\n\u518d\u9f0e\u91ab\u85e5\u6b63\u5728\u5927\u4e2d\u83ef\u5340\u62db\u52df\u60a3\u8005\u53c3\u52a0\u5168\u74033\u671f\u81e8\u5e8a\u7814\u7a76FORTITUDE-101\u548cFORTITUDE-102\uff1a<br \/>\nFORTITUDE-101\u662f\u4e00\u9805bemarituzumab\u806f\u5408\u5316\u7642\u7528\u65bc\u80c3\u764c\u4e00\u7dda\u6cbb\u7642\u76843\u671f\u81e8\u5e8a\u7814\u7a76\u3002       FORTITUDE-102\u662f\u4e00\u9805bemarituzumab\u806f\u5408\u5316\u7642\u548c\u7d0d\u6b66\u5229\u5c24\u55ae\u6297\u7528\u65bc\u80c3\u764c\u4e00\u7dda\u6cbb\u7642\u76841b\/3\u671f\u81e8\u5e8a\u7814\u7a76\u3002      <\/p>\n<p>Tisotumab Vedotin\uff08\u7d44\u7e54\u56e0\u5b50 ADC\uff09<br \/>\n2024\u5e744\u6708\uff0c\u518d\u9f0e\u91ab\u85e5\u5408\u4f5c\u5925\u4f34\u8f1d\u745e\u548cGenmab A\/S\u5ba3\u4f48\uff0c\u7f8e\u570b\u98df\u54c1\u85e5\u54c1\u76e3\u7763\u7ba1\u7406\u5c40\uff08FDA\uff09\u5df2\u7d93\u6279\u51c6\u4e86tisotumab vedotin (TIVDAK\u00ae\uff09\u7684sBLA\uff0c\u5b8c\u5168\u6279\u51c6\u5176\u7528\u65bc\u6cbb\u7642\u5316\u7642\u671f\u9593\u6216\u5316\u7642\u5f8c\u75be\u75c5\u767c\u751f\u9032\u5c55\u7684\u5fa9\u767c\u6027\u6216\u8f49\u79fb\u6027\u5bae\u9838\u764c\u60a3\u8005\u3002\u00a0\u518d\u9f0e\u91ab\u85e5\u6b63\u5728\u5927\u4e2d\u83ef\u5340\u53c3\u8207\u5176\u5168\u74033\u671f\u81e8\u5e8ainnovaTV 301\u548c\u64f4\u5c55\u7814\u7a76\u3002    <\/p>\n<p>Adagrasib (KRASG12C):<br \/>\n\u518d\u9f0e\u91ab\u85e5\u6b63\u5728\u8a55\u4f30\u5168\u74033\u671f\u81e8\u5e8a\u7814\u7a76KRYSTAL-12\u7684\u81e8\u5e8a\u6578\u64da\uff0c\u8a72\u7814\u7a76\u65e8\u5728\u8a55\u4f30adagrasib\u7528\u65bc\u5148\u524d\u7d93\u6cbb\u7684KRASG12C\u7a81\u8b8a\u975e\u5c0f\u7d30\u80de\u80ba\u764c\u60a3\u8005\uff0c\u540c\u6642\u6211\u5011\u5c07\u78ba\u5b9a\u8a72\u7522\u54c1\u4e0b\u4e00\u6b65\u7684\u9069\u61c9\u8b49\u958b\u767c\u3002    <\/p>\n<p>ZL-1310 (DLL3 ADC):\u00a0<br \/>\n2024\u5e743\u6708\uff0c\u518d\u9f0e\u91ab\u85e5\u5728\u6b50\u6d32\u80ba\u764c\u5927\u6703 (ELCC) \u4e0a\u516c\u4f48\u4e86ZL-1310\u81e8\u5e8a\u524d\u7814\u7a76\u7d50\u679c\uff0c\u5c55\u73fe\u4e86\u5176\u6cbb\u7642\u6f5b\u529b\u3002     \u518d\u9f0e\u91ab\u85e5\u6b63\u5728\u7f8e\u570b\u548c\u5927\u4e2d\u83ef\u5340\u70ba\u5176\u5168\u74031\u671f\u81e8\u5e8a\u7814\u7a76\u62db\u52df\u63a5\u53d7\u9251\u985e\u6cbb\u7642\u5f8c\u51fa\u73fe\u9032\u5c55\u7684\u5fa9\u767c\u548c\u96e3\u6cbb\u6027\u4e8c\u7dda\u53ca\u4ee5\u4e0a\u5c0f\u7d30\u80de\u80ba\u764c (SCLC) \u60a3\u8005\u3002    <\/p>\n<p>ZL-1218 (CCR8):\u00a0<br \/>\n\u518d\u9f0e\u91ab\u85e5\u6b63\u5728\u7f8e\u570b\u3001\u6b50\u6d32\u548c\u5927\u4e2d\u83ef\u5340\u70ba\u5176\u5168\u74031\u671f\u81e8\u5e8a\u7814\u7a76\u62db\u52df\u60a3\u8005\uff0c\u8a72\u7814\u7a76\u65e8\u5728\u8a55\u4f30ZL-1218\u55ae\u85e5\u4ee5\u53ca\u8207\u5e15\u535a\u5229\u73e0\u55ae\u6297\u806f\u5408\u6cbb\u7642\u665a\u671f\u60e1\u6027\u5be6\u9ad4\u7624\u3002    <\/p>\n<p>\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u3001\u611f\u67d3\u6027\u75be\u75c5\u548c\u4e2d\u6a1e\u795e\u7d93\u7cfb\u7d71\u75be\u75c5\u9818\u57df\u7ba1\u7dda<\/p>\n<p>\u827e\u52a0\u83ab\u5fb7\uff08FcRn\uff09\uff1a<br \/>\n2024\u5e744\u6708\uff0c\u518d\u9f0e\u91ab\u85e5\u5411\u4e2d\u570b\u570b\u5bb6\u85e5\u54c1\u76e3\u7763\u7ba1\u7406\u5c40\uff08NMPA\uff09\u63d0\u4ea4\u4e86\u827e\u52a0\u83ab\u5fb7\u76ae\u4e0b\u6ce8\u5c04\u5291\u578b\u7528\u65bc\u6162\u6027\u708e\u6027\u812b\u9ad3\u9798\u6027\u591a\u767c\u6027\u795e\u7d93\u6839\u795e\u7d93\u75c5\uff08CIDP\uff09\u7684sBLA\u3002    <\/p>\n<p>Xanomeline-Trospium\uff08KarXT\uff09\uff08M1\/M4\u578b\u6bd2\u8548\u9e7c\u4e59\u9170\u81bd\u9e7c\u53d7\u9ad4\u6fc0\u52d5\u5291\uff09:<br \/>\n2024\u5e744\u6708\uff0c\u518d\u9f0e\u91ab\u85e5\u5408\u4f5c\u5925\u4f34BMS\u5728\u570b\u969b\u7cbe\u795e\u5206\u88c2\u75c7\u7814\u7a76\u5b78\u6703 (SIRS) \u5e74\u6703\u4e0a\u516c\u4f48\u4e86\u65b0\u76843\u671f\u81e8\u5e8a\u7814\u7a76EMERGENT\u9805\u76ee\u7684\u9577\u671f\u6578\u64da\u4e2d\u671f\u5206\u6790\u3002<br \/>\n\u5728\u5c0d3\u671f\u958b\u653e\u6a19\u7c64\u64f4\u5c55\u7814\u7a76\u7684EMERGENT-4\u7684\u9577\u671f\u6709\u6548\u6027\u6578\u64da\u9032\u884c\u7684\u65b0\u7684\u4e2d\u671f\u5206\u6790\u4e2d\uff0cKarXT\u820752\u5468\u6642\u7cbe\u795e\u5206\u88c2\u75c7\u75c7\u72c0\u7684\u6240\u6709\u6709\u6548\u6027\u6307\u6a19\u7684\u986f\u8457\u6539\u5584\u76f8\u95dc\u3002       \u57283\u671f\u81e8\u5e8a\u7814\u7a76EMERGENT-4\u548cEMERGENT-5\u7684\u9577\u671f\u5b89\u5168\u6027\u4ee3\u8b1d\u7d50\u679c\u532f\u7e3d\u4e2d\u671f\u5206\u6790\u4e2d\uff0cKarXT\u8868\u73fe\u51fa\u826f\u597d\u7684\u9577\u671f\u4ee3\u8b1d\u7279\u5fb5\uff0c\u5927\u591a\u6578\u60a3\u8005\u572852\u5468\u7684\u6cbb\u7642\u4e2d\u7d93\u6b77\u4e86\u4ee3\u8b1d\u53c3\u6578\u7684\u7a69\u5b9a\u6216\u6539\u5584\u3002<br \/>\n     \u518d\u9f0e\u91ab\u85e5\u6b63\u5728\u4e2d\u570b\u5167\u5730\u62db\u52df\u60a3\u8005\u53c3\u52a0\u8a3b\u518a\u6027\u6a4b\u63a5\u7814\u7a76\u3002    <\/p>\n<p>2024\u5e74\u7684\u9810\u671f\u91cd\u8981\u91cc\u7a0b\u7891\u4e8b\u4ef6<\/p>\n<p>\u816b\u7624\u9818\u57df<\/p>\n<p>\u745e\u666e\u66ff\u5c3c<\/p>\n<p>\u745e\u666e\u66ff\u5c3c\u7528\u65bc\u6cbb\u7642ROS1\u967d\u6027\u5c40\u90e8\u665a\u671f\u6216\u8f49\u79fb\u6027NSCLC\u6210\u4eba\u60a3\u8005\u7684NDA\u6709\u671b\u7372NMPA\u6279\u51c6\u3002  <\/p>\n<p>\u816b\u7624\u96fb\u5834\u6cbb\u7642<\/p>\n<p>\u518d\u9f0e\u91ab\u85e5\u5c07\u5411NMPA\u63d0\u4ea4\u816b\u7624\u96fb\u5834\u6cbb\u7642\u7528\u65bc\u9251\u985e\u6cbb\u7642\u5f8c\u51fa\u73fe\u75be\u75c5\u9032\u5c55\u7684\u4e8c\u7dda\u53ca\u4ee5\u4e0aNSCLC \u7684\u4e0a\u5e02\u8a31\u53ef\u7533\u8acb\uff08MAA\uff09\u3002   Novocure\u5c07\u65bc2024\u5e74\u7b2c\u56db\u5b63\u5ea6\u516c\u4f48\u7528\u65bc\u5c40\u90e8\u665a\u671f\u80f0\u817a\u764c\u76843\u671f\u81e8\u5e8a\u7814\u7a76PANOVA-3\u7684\u4e3b\u8981\u6578\u64da\u3002\u518d\u9f0e\u91ab\u85e5\u6b63\u5728\u5927\u4e2d\u83ef\u5340\u53c3\u8207\u9019\u9805\u7814\u7a76\u3002  <\/p>\n<p>ZL-1310 (DLL3 ADC) <\/p>\n<p>\u6709\u671b\u57282024\u5e74\u5e95\u62162025\u5e74\u521d\u516c\u4f48\u7528\u65bc\u5fa9\u767c\u548c\u96e3\u6cbb\u6027\u4e8c\u7dda\u53ca\u4ee5\u4e0aSCLC\u60a3\u8005\u7684\u5168\u74031\u671f\u7814\u7a76\u7684\u5291\u91cf\u905e\u589e\u6578\u64da\u3002  <\/p>\n<p>\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u3001\u611f\u67d3\u6027\u75be\u75c5\u548c\u4e2d\u6a1e\u795e\u7d93\u7cfb\u7d71\u75be\u75c5\u9818\u57df<\/p>\n<p>\u827e\u52a0\u83ab\u5fb7\uff08FcRn\uff09<\/p>\n<p>\u827e\u52a0\u83ab\u5fb7\u76ae\u4e0b\u6ce8\u5c04\u5291\u578b\u7528\u65bcgMG\u7684\u751f\u7269\u88fd\u54c1\u4e0a\u5e02\u7533\u8acb\u6709\u671b\u7372NMPA\u6279\u51c6 \u3002   \u518d\u9f0e\u91ab\u85e5\u8a08\u5283\u65bc2024\u5e74\u4e0b\u534a\u5e74\u5728\u5927\u4e2d\u83ef\u5340\u53c3\u8207\u827e\u52a0\u83ab\u5fb7\u76ae\u4e0b\u6ce8\u5c04\u5291\u578b\u7528\u65bc\u6cbb\u7642\u7532\u72c0\u817a\u773c\u75c5\uff08TED\uff09\u7684\u8a3b\u518a\u6027\u81e8\u5e8a\u7814\u7a76\u3002  <\/p>\n<p>\u8212\u5df4\u5766\u9209-\u5ea6\u6d1b\u5df4\u5766\u9209\uff08SUL-DUR\uff09<\/p>\n<p>\u7528\u65bc\u6cbb\u7642\u7531\u9b91\u66fc\u4e0d\u52d5\u687f\u83cc-\u918b\u9178\u9223\u5fa9\u5408\u9ad4\uff08ABC\uff09\u7684\u654f\u611f\u5206\u96e2\u682a\u5f15\u8d77\u7684\u611f\u67d3\u7684NDA\u6709\u671b\u7372NMPA\u6279\u51c6\u3002  <\/p>\n<p>Xanomeline-Trospium (KarXT)\uff08M1\/M4\u578b\u6bd2\u8548\u9e7c\u4e59\u9170\u81bd\u9e7c\u53d7\u9ad4\u6fc0\u52d5\u5291\uff09<\/p>\n<p>\u518d\u9f0e\u91ab\u85e5\u5c07\u5b8c\u6210\u5728\u4e2d\u570b\u7528\u65bc\u7cbe\u795e\u5206\u88c2\u75c7\u7684\u6a4b\u63a5\u7814\u7a76\u7684\u60a3\u8005\u5165\u7d44\u3002   \u518d\u9f0e\u91ab\u85e5\u5c07\u65bc\u5e74\u4e2d\u5728\u5927\u4e2d\u83ef\u5340\u52a0\u5165\u963f\u723e\u8328\u6d77\u9ed8\u75c7\u76f8\u95dc\u7684\u7cbe\u795e\u75be\u75c5\u7684\u5168\u74033\u671f\u7814\u7a76ADEPT-2\u548cADEPT-3 \u3002   BMS\u5c07\u57282024\u5e74\u4e0b\u534a\u5e74\u516c\u4f48EMERGENT-4\u548cEMERGENT-5\u7814\u7a76\u7684\u6578\u64da\uff0c\u4ee5\u8a55\u4f30\u7cbe\u795e\u5206\u88c2\u75c7\u6cbb\u7642\u7684\u9577\u671f\u5b89\u5168\u6027\u3002  <\/p>\n<p>ZL-1102 (IL-17 Humabody\u00ae)<\/p>\n<p>\u518d\u9f0e\u91ab\u85e5\u5c07\u65bc2024\u5e74\u7b2c\u4e8c\u5b63\u5ea6\u555f\u52d5\u91dd\u5c0d\u8f15\u4e2d\u5ea6\u6162\u6027\u6591\u584a\u72c0\u9280\u5c51\u75c5\u7684\u5168\u74032\u671f\u7814\u7a76\u3002  <\/p>\n<p>\u96fb\u8a71\u6703\u8b70\u548c\u7db2\u7d61\u76f4\u64ad\u76f8\u95dc\u4fe1\u606f<\/p>\n<p>\u518d\u9f0e\u91ab\u85e5\u5c07\u65bc\u7f8e\u570b\u6771\u90e8\u6642\u95932024\u5e745\u67089\u65e5\u4e0a\u53488\u9ede\uff08\u5317\u4eac\u6642\u9593\u665a\u4e0a8\u9ede\uff09\u8209\u884c\u96fb\u8a71\u6703\u8b70\u548c\u7db2\u7d61\u76f4\u64ad\u3002\u8207\u6703\u8005\u53ef\u4ee5\u8a2a\u554f\u516c\u53f8\u7db2\u7ad9<a href=\"http:\/\/ir.zailaboratory.com\/\" target=\"_blank\" rel=\"noopener\">http:\/\/ir.zailaboratory.com<\/a>\u53c3\u8207\u5be6\u6642\u7db2\u7d61\u76f4\u64ad\u3002\u5982\u8981\u53c3\u52a0\u96fb\u8a71\u6703\u8b70\uff0c\u9700\u63d0\u524d\u8a3b\u518a\u3002<\/p>\n<p>\u8a73\u7d30\u4fe1\u606f\u5982\u4e0b\uff1a<\/p>\n<p>\u8a3b\u518a\u93c8\u63a5\uff1a<a href=\"https:\/\/register.vevent.com\/register\/BIb8622a7cf98e46cd9bc9198a5f105c36\" target=\"_blank\" rel=\"noopener\">https:\/\/register.vevent.com\/register\/BIb8622a7cf98e46cd9bc9198a5f105c36<\/a><\/p>\n<p>\u6240\u6709\u8207\u6703\u8005\u90fd\u5fc5\u9808\u5728\u96fb\u8a71\u6703\u8b70\u4e4b\u524d\u901a\u904e\u4e0a\u65b9\u93c8\u63a5\u5b8c\u6210\u5728\u7dda\u8a3b\u518a\u3002\u8a3b\u518a\u6210\u529f\u5f8c\uff0c\u60a8\u5c07\u6536\u5230\u78ba\u8a8d\u90f5\u4ef6\uff0c\u5167\u542b\u64a5\u5165\u96fb\u8a71\u6703\u8b70\u7684\u5177\u9ad4\u4fe1\u606f\u3002<\/p>\n<p>\u6703\u8b70\u7d50\u675f\u5f8c\uff0c\u60a8\u53ef\u901a\u904e\u8a2a\u554f\u518d\u9f0e\u91ab\u85e5\u7db2\u7ad9\u89c0\u770b\u56de\u653e\u3002<\/p>\n<p>\u95dc\u65bc\u518d\u9f0e\u91ab\u85e5<\/p>\n<p>\u518d\u9f0e\u91ab\u85e5\uff08\u7d0d\u65af\u9054\u514b\u80a1\u7968\u4ee3\u78bc\uff1aZLAB\uff1b\u00a0\u9999\u6e2f\u806f\u4ea4\u6240\u80a1\u4efd\u4ee3\u865f\uff1a9688\uff09\u662f\u4e00\u5bb6\u4ee5\u7814\u767c\u70ba\u57fa\u790e\u3001\u8655\u65bc\u5546\u696d\u5316\u968e\u6bb5\u7684\u5275\u65b0\u578b\u751f\u7269\u88fd\u85e5\u516c\u53f8\uff0c\u7e3d\u90e8\u4f4d\u65bc\u4e2d\u570b\u548c\u7f8e\u570b\u3002\u6211\u5011\u81f4\u529b\u65bc\u901a\u904e\u5275\u65b0\u7522\u54c1\u7684\u767c\u73fe\u3001\u958b\u767c\u548c\u5546\u696d\u5316\u89e3\u6c7a\u816b\u7624\u3001\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u3001\u611f\u67d3\u6027\u75be\u75c5\u548c\u4e2d\u6a1e\u795e\u7d93\u7cfb\u7d71\u75be\u75c5\u9818\u57df\u672a\u88ab\u6eff\u8db3\u7684\u5de8\u5927\u91ab\u7642\u9700\u6c42\u3002\u6211\u5011\u7684\u76ee\u6a19\u662f\u5229\u7528\u6211\u5011\u7684\u80fd\u529b\u548c\u8cc7\u6e90\u52aa\u529b\u4fc3\u9032\u4e2d\u570b\u53ca\u5168\u4e16\u754c\u4eba\u985e\u7684\u5065\u5eb7\u798f\u7949\u3002<\/p>\n<p>\u6709\u95dc\u518d\u9f0e\u91ab\u85e5\u7684\u66f4\u591a\u4fe1\u606f\uff0c\u8acb\u8a2a\u554f<a href=\"http:\/\/www.zailaboratory.com\/\" target=\"_blank\" rel=\"noopener\">www.zailaboratory.com<\/a>\u6216\u95dc\u6ce8\u516c\u53f8\u5b98\u5fae\uff1a\u518d\u9f0e\u91ab\u85e5\u3002<\/p>\n<div>\n<p class=\"prnml4\"><span class=\"prnews_span\">1 \u73fe\u91d1\u5132\u5099\u5305\u62ec\u73fe\u91d1\u53ca\u73fe\u91d1\u7b49\u50f9\u7269\u3001\u6d41\u52d5\u53d7\u9650\u5236\u73fe\u91d1\u548c\u77ed\u671f\u6295\u8cc7\u3002<\/span><\/p>\n<p class=\"prnml4\"><span class=\"prnews_span\">2\u00a0\u4e2d\u570b\u5927\u9678\uff08\u5167\u5730\uff09\u3001\u9999\u6e2f\u3001\u6fb3\u9580\u548c\u53f0\u7063\u5730\u5340\u00a0(\u5408\u7a31\u5927\u4e2d\u83ef\u5340)\u3002<\/span><\/p>\n<\/div>\n<p>\u00a0<\/p>","protected":false},"excerpt":{"rendered":"<p>2024\u5e74\u7b2c\u4e00\u5b63\u5ea6\u7522\u54c1\u6536\u5165\u6de8\u984d\u5408\u8a08\u70ba8,710\u842c\u7f8e\u5143\uff0c\u540c\u6bd4\u589e\u957739%\uff1b\u00a0\u6309\u56fa\u5b9a\u532f\u7387\uff08CER\uff09\u8a08\u7b97\u540c\u6bd4\u589e\u957743% \u885b\u5049\u8fe6\u00ae\uff08\u827e\u52a0\u83ab\u5fb7\u03b1\u6ce8\u5c04\u6db2\uff092024\u5e74\u7b2c\u4e00\u5b63\u5ea6\u92b7\u552e\u984d\u70ba1,320\u842c\u7f8e\u5143\uff0c\u4e3b\u8981\u662f\u7531\u65bc\u60a3\u8005\u53ef\u53ca\u6027\u7684\u589e\u52a0\uff1b\u64da\u4f30\u7b97\u7d04\u67092,700\u540d\u65b0\u589e\u60a3\u8005\u65bc2024\u5e74\u7b2c\u4e00\u5b63\u5ea6\u63a5\u53d7\u4e86\u885b\u5049\u8fe6\u7684\u6cbb\u7642 \u8212\u5df4\u5766\u9209-\u5ea6\u6d1b\u5df4\u5766\u9209\u7528\u65bc\u9b91\u66fc\u4e0d\u52d5\u687f\u83cc-\u918b\u9178\u9223\u5fa9\u5408\u9ad4\uff08ABC\uff09\u7684\u654f\u611f\u5206\u96e2\u682a\u3001\u827e\u52a0\u83ab\u5fb7\u76ae\u4e0b\u6ce8\u5c04\u5291\u578b\u7528\u65bc\u5168\u8eab\u578b\u91cd\u75c7\u808c\u7121\u529b\uff08gMG\uff09\u3001\u745e\u666e\u66ff\u5c3c\u7528\u65bcROS1\u967d\u6027\u975e\u5c0f\u7d30\u80de\u80ba\u764c\uff08NSCLC\uff09\u6b63\u5728\u8a3b\u518a\u5be9\u8a55\u4e2d\uff1b\u827e\u52a0\u83ab\u5fb7\u76ae\u4e0b\u6ce8\u5c04\u5291\u578b\u7528\u65bc\u6162\u6027\u708e\u6027\u812b\u9ad3\u9798\u6027\u591a\u767c\u6027\u795e\u7d93\u6839\u795e\u7d93\u75c5\uff08CIDP\uff09\u7684\u88dc\u5145\u751f\u7269\u88fd\u54c1\u4e0a\u5e02\u7533\u8acb\uff08sBLA\uff09\u5df2\u7d93\u63d0\u4ea4 \u7a69\u5065\u7684\u8cc7\u7522\u8ca0\u50b5\u72c0\u6cc1\uff0c\u622a\u81f32024\u5e743\u670831\u65e5\u73fe\u91d1\u5132\u50991\u70ba7.508\u5104\u7f8e\u5143\uff0c\u800c\u622a\u81f32023\u5e7412\u670831\u65e5\u70ba8.065\u5104\u7f8e\u5143 \u516c\u53f8\u5c07\u65bc\u7f8e\u570b\u6771\u90e8\u6642\u95932024\u5e745\u67089\u65e5\u4e0a\u53488:00\uff08\u5317\u4eac\u6642\u9593\u665a\u4e0a8:00\uff09\u8209\u884c\u96fb\u8a71\u6703\u8b70\u548c\u7db2\u7d61\u76f4\u64ad \u4e2d\u570b\u4e0a\u6d77\u548c\u7f8e\u570b\u99ac\u85a9\u8af8\u585e\u5dde\u528d\u6a4b2024\u5e745\u67089\u65e5 \/\u7f8e\u901a\u793e\/ &#8212; \u518d\u9f0e\u91ab\u85e5\u6709\u9650\u516c\u53f8\uff08\u7d0d\u65af\u9054\u514b\u80a1\u7968\u4ee3\u78bc\uff1aZLAB\uff1b\u9999\u6e2f\u806f\u4ea4\u6240\u80a1\u4efd\u4ee3\u865f\uff1a9688\uff09\u516c\u4f48\u4e862024\u5e74\u7b2c\u4e00\u5b63\u5ea6\u7684\u8ca1\u52d9\u696d\u7e3e\uff0c\u4ee5\u53ca\u8fd1\u671f\u7684\u7522\u54c1\u4eae\u9ede\u548c\u516c\u53f8\u9032\u5c55\u3002 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\u518d\u9f0e\u91ab\u85e5\u6b63\u5728\u5927\u4e2d\u83ef\u5340\u62db\u52df\u60a3\u8005\u53c3\u52a0\u5168\u74033\u671f\u81e8\u5e8a\u7814\u7a76FORTITUDE-101\u548cFORTITUDE-102\uff1a FORTITUDE-101\u662f\u4e00\u9805bemarituzumab\u806f\u5408\u5316\u7642\u7528\u65bc\u80c3\u764c\u4e00\u7dda\u6cbb\u7642\u76843\u671f\u81e8\u5e8a\u7814\u7a76\u3002 FORTITUDE-102\u662f\u4e00\u9805bemarituzumab\u806f\u5408\u5316\u7642\u548c\u7d0d\u6b66\u5229\u5c24\u55ae\u6297\u7528\u65bc\u80c3\u764c\u4e00\u7dda\u6cbb\u7642\u76841b\/3\u671f\u81e8\u5e8a\u7814\u7a76\u3002 Tisotumab Vedotin\uff08\u7d44\u7e54\u56e0\u5b50 ADC\uff09 2024\u5e744\u6708\uff0c\u518d\u9f0e\u91ab\u85e5\u5408\u4f5c\u5925\u4f34\u8f1d\u745e\u548cGenmab A\/S\u5ba3\u4f48\uff0c\u7f8e\u570b\u98df\u54c1\u85e5\u54c1\u76e3\u7763\u7ba1\u7406\u5c40\uff08FDA\uff09\u5df2\u7d93\u6279\u51c6\u4e86tisotumab vedotin (TIVDAK\u00ae\uff09\u7684sBLA\uff0c\u5b8c\u5168\u6279\u51c6\u5176\u7528\u65bc\u6cbb\u7642\u5316\u7642\u671f\u9593\u6216\u5316\u7642\u5f8c\u75be\u75c5\u767c\u751f\u9032\u5c55\u7684\u5fa9\u767c\u6027\u6216\u8f49\u79fb\u6027\u5bae\u9838\u764c\u60a3\u8005\u3002\u00a0\u518d\u9f0e\u91ab\u85e5\u6b63\u5728\u5927\u4e2d\u83ef\u5340\u53c3\u8207\u5176\u5168\u74033\u671f\u81e8\u5e8ainnovaTV 301\u548c\u64f4\u5c55\u7814\u7a76\u3002 Adagrasib (KRASG12C): \u518d\u9f0e\u91ab\u85e5\u6b63\u5728\u8a55\u4f30\u5168\u74033\u671f\u81e8\u5e8a\u7814\u7a76KRYSTAL-12\u7684\u81e8\u5e8a\u6578\u64da\uff0c\u8a72\u7814\u7a76\u65e8\u5728\u8a55\u4f30adagrasib\u7528\u65bc\u5148\u524d\u7d93\u6cbb\u7684KRASG12C\u7a81\u8b8a\u975e\u5c0f\u7d30\u80de\u80ba\u764c\u60a3\u8005\uff0c\u540c\u6642\u6211\u5011\u5c07\u78ba\u5b9a\u8a72\u7522\u54c1\u4e0b\u4e00\u6b65\u7684\u9069\u61c9\u8b49\u958b\u767c\u3002 ZL-1310 (DLL3 ADC):\u00a0 2024\u5e743\u6708\uff0c\u518d\u9f0e\u91ab\u85e5\u5728\u6b50\u6d32\u80ba\u764c\u5927\u6703 (ELCC) \u4e0a\u516c\u4f48\u4e86ZL-1310\u81e8\u5e8a\u524d\u7814\u7a76\u7d50\u679c\uff0c\u5c55\u73fe\u4e86\u5176\u6cbb\u7642\u6f5b\u529b\u3002 \u518d\u9f0e\u91ab\u85e5\u6b63\u5728\u7f8e\u570b\u548c\u5927\u4e2d\u83ef\u5340\u70ba\u5176\u5168\u74031\u671f\u81e8\u5e8a\u7814\u7a76\u62db\u52df\u63a5\u53d7\u9251\u985e\u6cbb\u7642\u5f8c\u51fa\u73fe\u9032\u5c55\u7684\u5fa9\u767c\u548c\u96e3\u6cbb\u6027\u4e8c\u7dda\u53ca\u4ee5\u4e0a\u5c0f\u7d30\u80de\u80ba\u764c (SCLC) \u60a3\u8005\u3002 ZL-1218 (CCR8):\u00a0 \u518d\u9f0e\u91ab\u85e5\u6b63\u5728\u7f8e\u570b\u3001\u6b50\u6d32\u548c\u5927\u4e2d\u83ef\u5340\u70ba\u5176\u5168\u74031\u671f\u81e8\u5e8a\u7814\u7a76\u62db\u52df\u60a3\u8005\uff0c\u8a72\u7814\u7a76\u65e8\u5728\u8a55\u4f30ZL-1218\u55ae\u85e5\u4ee5\u53ca\u8207\u5e15\u535a\u5229\u73e0\u55ae\u6297\u806f\u5408\u6cbb\u7642\u665a\u671f\u60e1\u6027\u5be6\u9ad4\u7624\u3002 \u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u3001\u611f\u67d3\u6027\u75be\u75c5\u548c\u4e2d\u6a1e\u795e\u7d93\u7cfb\u7d71\u75be\u75c5\u9818\u57df\u7ba1\u7dda \u827e\u52a0\u83ab\u5fb7\uff08FcRn\uff09\uff1a 2024\u5e744\u6708\uff0c\u518d\u9f0e\u91ab\u85e5\u5411\u4e2d\u570b\u570b\u5bb6\u85e5\u54c1\u76e3\u7763\u7ba1\u7406\u5c40\uff08NMPA\uff09\u63d0\u4ea4\u4e86\u827e\u52a0\u83ab\u5fb7\u76ae\u4e0b\u6ce8\u5c04\u5291\u578b\u7528\u65bc\u6162\u6027\u708e\u6027\u812b\u9ad3\u9798\u6027\u591a\u767c\u6027\u795e\u7d93\u6839\u795e\u7d93\u75c5\uff08CIDP\uff09\u7684sBLA\u3002 Xanomeline-Trospium\uff08KarXT\uff09\uff08M1\/M4\u578b\u6bd2\u8548\u9e7c\u4e59\u9170\u81bd\u9e7c\u53d7\u9ad4\u6fc0\u52d5\u5291\uff09: 2024\u5e744\u6708\uff0c\u518d\u9f0e\u91ab\u85e5\u5408\u4f5c\u5925\u4f34BMS\u5728\u570b\u969b\u7cbe\u795e\u5206\u88c2\u75c7\u7814\u7a76\u5b78\u6703 (SIRS) \u5e74\u6703\u4e0a\u516c\u4f48\u4e86\u65b0\u76843\u671f\u81e8\u5e8a\u7814\u7a76EMERGENT\u9805\u76ee\u7684\u9577\u671f\u6578\u64da\u4e2d\u671f\u5206\u6790\u3002 \u5728\u5c0d3\u671f\u958b\u653e\u6a19\u7c64\u64f4\u5c55\u7814\u7a76\u7684EMERGENT-4\u7684\u9577\u671f\u6709\u6548\u6027\u6578\u64da\u9032\u884c\u7684\u65b0\u7684\u4e2d\u671f\u5206\u6790\u4e2d\uff0cKarXT\u820752\u5468\u6642\u7cbe\u795e\u5206\u88c2\u75c7\u75c7\u72c0\u7684\u6240\u6709\u6709\u6548\u6027\u6307\u6a19\u7684\u986f\u8457\u6539\u5584\u76f8\u95dc\u3002 \u57283\u671f\u81e8\u5e8a\u7814\u7a76EMERGENT-4\u548cEMERGENT-5\u7684\u9577\u671f\u5b89\u5168\u6027\u4ee3\u8b1d\u7d50\u679c\u532f\u7e3d\u4e2d\u671f\u5206\u6790\u4e2d\uff0cKarXT\u8868\u73fe\u51fa\u826f\u597d\u7684\u9577\u671f\u4ee3\u8b1d\u7279\u5fb5\uff0c\u5927\u591a\u6578\u60a3\u8005\u572852\u5468\u7684\u6cbb\u7642\u4e2d\u7d93\u6b77\u4e86\u4ee3\u8b1d\u53c3\u6578\u7684\u7a69\u5b9a\u6216\u6539\u5584\u3002 \u518d\u9f0e\u91ab\u85e5\u6b63\u5728\u4e2d\u570b\u5167\u5730\u62db\u52df\u60a3\u8005\u53c3\u52a0\u8a3b\u518a\u6027\u6a4b\u63a5\u7814\u7a76\u3002 2024\u5e74\u7684\u9810\u671f\u91cd\u8981\u91cc\u7a0b\u7891\u4e8b\u4ef6 \u816b\u7624\u9818\u57df \u745e\u666e\u66ff\u5c3c \u745e\u666e\u66ff\u5c3c\u7528\u65bc\u6cbb\u7642ROS1\u967d\u6027\u5c40\u90e8\u665a\u671f\u6216\u8f49\u79fb\u6027NSCLC\u6210\u4eba\u60a3\u8005\u7684NDA\u6709\u671b\u7372NMPA\u6279\u51c6\u3002 \u816b\u7624\u96fb\u5834\u6cbb\u7642 \u518d\u9f0e\u91ab\u85e5\u5c07\u5411NMPA\u63d0\u4ea4\u816b\u7624\u96fb\u5834\u6cbb\u7642\u7528\u65bc\u9251\u985e\u6cbb\u7642\u5f8c\u51fa\u73fe\u75be\u75c5\u9032\u5c55\u7684\u4e8c\u7dda\u53ca\u4ee5\u4e0aNSCLC \u7684\u4e0a\u5e02\u8a31\u53ef\u7533\u8acb\uff08MAA\uff09\u3002 Novocure\u5c07\u65bc2024\u5e74\u7b2c\u56db\u5b63\u5ea6\u516c\u4f48\u7528\u65bc\u5c40\u90e8\u665a\u671f\u80f0\u817a\u764c\u76843\u671f\u81e8\u5e8a\u7814\u7a76PANOVA-3\u7684\u4e3b\u8981\u6578\u64da\u3002\u518d\u9f0e\u91ab\u85e5\u6b63\u5728\u5927\u4e2d\u83ef\u5340\u53c3\u8207\u9019\u9805\u7814\u7a76\u3002 ZL-1310 (DLL3 ADC) \u6709\u671b\u57282024\u5e74\u5e95\u62162025\u5e74\u521d\u516c\u4f48\u7528\u65bc\u5fa9\u767c\u548c\u96e3\u6cbb\u6027\u4e8c\u7dda\u53ca\u4ee5\u4e0aSCLC\u60a3\u8005\u7684\u5168\u74031\u671f\u7814\u7a76\u7684\u5291\u91cf\u905e\u589e\u6578\u64da\u3002 \u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u3001\u611f\u67d3\u6027\u75be\u75c5\u548c\u4e2d\u6a1e\u795e\u7d93\u7cfb\u7d71\u75be\u75c5\u9818\u57df \u827e\u52a0\u83ab\u5fb7\uff08FcRn\uff09 \u827e\u52a0\u83ab\u5fb7\u76ae\u4e0b\u6ce8\u5c04\u5291\u578b\u7528\u65bcgMG\u7684\u751f\u7269\u88fd\u54c1\u4e0a\u5e02\u7533\u8acb\u6709\u671b\u7372NMPA\u6279\u51c6 \u3002 \u518d\u9f0e\u91ab\u85e5\u8a08\u5283\u65bc2024\u5e74\u4e0b\u534a\u5e74\u5728\u5927\u4e2d\u83ef\u5340\u53c3\u8207\u827e\u52a0\u83ab\u5fb7\u76ae\u4e0b\u6ce8\u5c04\u5291\u578b\u7528\u65bc\u6cbb\u7642\u7532\u72c0\u817a\u773c\u75c5\uff08TED\uff09\u7684\u8a3b\u518a\u6027\u81e8\u5e8a\u7814\u7a76\u3002 \u8212\u5df4\u5766\u9209-\u5ea6\u6d1b\u5df4\u5766\u9209\uff08SUL-DUR\uff09 \u7528\u65bc\u6cbb\u7642\u7531\u9b91\u66fc\u4e0d\u52d5\u687f\u83cc-\u918b\u9178\u9223\u5fa9\u5408\u9ad4\uff08ABC\uff09\u7684\u654f\u611f\u5206\u96e2\u682a\u5f15\u8d77\u7684\u611f\u67d3\u7684NDA\u6709\u671b\u7372NMPA\u6279\u51c6\u3002 Xanomeline-Trospium (KarXT)\uff08M1\/M4\u578b\u6bd2\u8548\u9e7c\u4e59\u9170\u81bd\u9e7c\u53d7\u9ad4\u6fc0\u52d5\u5291\uff09 \u518d\u9f0e\u91ab\u85e5\u5c07\u5b8c\u6210\u5728\u4e2d\u570b\u7528\u65bc\u7cbe\u795e\u5206\u88c2\u75c7\u7684\u6a4b\u63a5\u7814\u7a76\u7684\u60a3\u8005\u5165\u7d44\u3002 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\u518d\u9f0e\u91ab\u85e5\u5c07\u65bc\u7f8e\u570b\u6771\u90e8\u6642\u95932024\u5e745\u67089\u65e5\u4e0a\u53488\u9ede\uff08\u5317\u4eac\u6642\u9593\u665a\u4e0a8\u9ede\uff09\u8209\u884c\u96fb\u8a71\u6703\u8b70\u548c\u7db2\u7d61\u76f4\u64ad\u3002\u8207\u6703\u8005\u53ef\u4ee5\u8a2a\u554f\u516c\u53f8\u7db2\u7ad9http:\/\/ir.zailaboratory.com\u53c3\u8207\u5be6\u6642\u7db2\u7d61\u76f4\u64ad\u3002\u5982\u8981\u53c3\u52a0\u96fb\u8a71\u6703\u8b70\uff0c\u9700\u63d0\u524d\u8a3b\u518a\u3002 \u8a73\u7d30\u4fe1\u606f\u5982\u4e0b\uff1a \u8a3b\u518a\u93c8\u63a5\uff1ahttps:\/\/register.vevent.com\/register\/BIb8622a7cf98e46cd9bc9198a5f105c36 \u6240\u6709\u8207\u6703\u8005\u90fd\u5fc5\u9808\u5728\u96fb\u8a71\u6703\u8b70\u4e4b\u524d\u901a\u904e\u4e0a\u65b9\u93c8\u63a5\u5b8c\u6210\u5728\u7dda\u8a3b\u518a\u3002\u8a3b\u518a\u6210\u529f\u5f8c\uff0c\u60a8\u5c07\u6536\u5230\u78ba\u8a8d\u90f5\u4ef6\uff0c\u5167\u542b\u64a5\u5165\u96fb\u8a71\u6703\u8b70\u7684\u5177\u9ad4\u4fe1\u606f\u3002 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\u64ce\u6a02\u00ae\uff1a2024\u5e74\u7b2c\u4e00\u5b63\u5ea6\u92b7\u552e\u6536\u5165\u70ba610\u842c\u7f8e\u5143\uff0c2023\u5e74\u540c\u671f\u70ba130\u842c\u7f8e\u5143\uff0c\u540c\u6bd4\u589e\u9577367%\uff0c\u4e3b\u8981\u662f\u7531\u65bc\u5176\u65bc2023\u5e74\u7b2c\u4e00\u5b63\u5ea6\u88ab\u7d0d\u5165NRDL\uff0c\u7528\u65bc\u665a\u671f\u56db\u7dda\u80c3\u8178\u9593\u8cea\u7624\uff08GIST\uff09\u7684\u6cbb\u7642\u3002 \u7d10\u518d\u6a02\u00ae\uff1a2024\u5e74\u7b2c\u4e00\u5b63\u5ea6\u92b7\u552e\u6536\u5165\u70ba990\u842c\u7f8e\u5143\uff0c2023\u5e74\u540c\u671f\u70ba550\u842c\u7f8e\u5143\uff0c\u540c\u6bd4\u589e\u957781%\uff0c\u4e3b\u8981\u662f\u7531\u65bc\u7d10\u518d\u6a02\u975c\u8108\u6ce8\u5c04\u5291\u578b\u65bc2023\u5e74\u7b2c\u4e00\u5b63\u5ea6\u88ab\u7d0d\u5165NRDL\uff0c\u7528\u65bc\u6cbb\u7642\u6210\u4eba\u793e\u5340\u7372\u5f97\u6027\u7d30\u83cc\u6027\u80ba\u708e (CABP) \u548c\u6025\u6027\u7d30\u83cc\u6027\u76ae\u819a\u548c\u76ae\u819a\u7d50\u69cb\u611f\u67d3 (ABSSSI)\uff0c2024\u5e74\u7b2c\u4e00\u5b63\u5ea6\u4e0a\u8ff0\u9069\u61c9\u8b49\u7684\u53e3\u670d\u5291\u578b\u88ab\u7d0d\u5165NRDL\u3002 2024\u5e74\u7b2c\u4e00\u5b63\u5ea6\u7684\u7814\u767c\u958b\u652f\u70ba5,460\u842c\u7f8e\u5143\uff0c2023\u5e74\u540c\u671f\u70ba4,850\u842c\u7f8e\u5143\u3002\u9019\u4e00\u589e\u9577\u4e3b\u8981\u662f\u7531\u65bc\u65b0\u555f\u52d5\u548c\u6b63\u5728\u958b\u5c55\u7684\u81e8\u5e8a\u7814\u7a76\u7684\u8cbb\u7528\u7684\u589e\u52a0\uff0c\u90e8\u5206\u88ab\u8a31\u53ef\u7522\u54c1\u7684\u91cc\u7a0b\u7891\u6b3e\u9805\u7684\u6e1b\u5c11\u6240\u62b5\u92b7\u3002 2024\u5e74\u7b2c\u4e00\u5b63\u5ea6\u7684\u92b7\u552e\u3001\u4e00\u822c\u548c\u884c\u653f\u958b\u652f\u70ba6,920\u842c\u7f8e\u5143\uff0c2023\u5e74\u540c\u671f\u70ba6,250\u842c\u7f8e\u5143\u3002\u9019\u4e00\u589e\u9577\u4e3b\u8981\u662f\u7531\u65bc\u8207\u885b\u5049\u8fe6\u4e0a\u5e02\u6709\u95dc\u7684\u4e00\u822c\u92b7\u552e\u8cbb\u7528\u7684\u589e\u9577\u548c\u4eba\u54e1\u7684\u589e\u52a0\u3002 2024\u5e74\u7b2c\u4e00\u5b63\u5ea6\u8667\u640d\u6de8\u984d\u70ba5,350\u842c\u7f8e\u5143\uff0c\u6bcf\u80a1\u666e\u901a\u80a1\u8667\u640d0.05\u7f8e\u5143\uff08\u6bcf\u4efd\u7f8e\u570b\u5b58\u6258\u80a1\u4efd\uff08ADS\uff09\u8667\u640d\u70ba0.55\u7f8e\u5143\uff09\uff0c2023\u5e74\u540c\u671f\u8667\u640d\u6de8\u984d\u70ba4,910\u842c\u7f8e\u5143\u3002\u6bcf\u80a1\u666e\u901a\u80a1\u8667\u640d0.05\u7f8e\u5143\uff08\u6bcf\u4efdADS\u8667\u640d\u70ba0.51\u7f8e\u5143\uff09\u3002 \u622a\u81f32024\u5e743\u670831\u65e5\uff0c\u73fe\u91d1\u53ca\u73fe\u91d1\u7b49\u50f9\u7269\u3001\u77ed\u671f\u6295\u8cc7\u3001\u6d41\u52d5\u53d7\u9650\u5236\u73fe\u91d1\u7e3d\u8a08\u70ba7.508\u5104\u7f8e\u5143\uff0c\u622a\u81f32023\u5e7412\u670831\u65e5\u70ba8.065\u5104\u7f8e\u5143\u3002 \u516c\u53f8\u9032\u5c55 2024\u5e744\u6708\uff0c\u6731\u5f64\u5148\u751f\u52a0\u5165\u518d\u9f0e\u91ab\u85e5\uff0c\u64d4\u4efb\u5927\u4e2d\u83ef\u53402\u9996\u5e2d\u5546\u52d9\u5b98\u3002\u6731\u5f64\u5148\u751f\u5728\u69cb\u5efa\u5275\u65b0\u5546\u696d\u6a21\u5f0f\u548c\u8cc7\u6e90\u6574\u5408\u65b9\u9762\u64c1\u6709\u8c50\u5bcc\u7684\u7d93\u9a57\uff0c\u5c07\u5e6b\u52a9\u6211\u5011\u9032\u4e00\u6b65\u52a0\u5f37\u5546\u696d\u5316\u904b\u71df\uff0c\u63a8\u52d5\u5927\u4e2d\u83ef\u5340\u7684\u92b7\u552e\u548c\u5229\u6f64\u589e\u9577\u3002\u5728\u52a0\u5165\u518d\u9f0e\u91ab\u85e5\u4e4b\u524d\uff0c\u4ed6\u5728\u5148\u8072\u518d\u660e\u4efb\u8077\uff0c\u6700\u8fd1\u7684\u8077\u4f4d\u70ba\u9996\u5e2d\u904b\u71df\u5b98\uff0c\u8ca0\u8cac\u71df\u92b7\u548c\u88fd\u85e5\u696d\u52d9\u3002\u5728\u6b64\u4e4b\u524d\uff0c\u4ed6\u66fe\u5728\u963f\u65af\u5229\u5eb7\u3001\u7f85\u6c0f\u3001\u8cfd\u8afe\u83f2\u548c\u767e\u6642\u7f8e\u65bd\u8cb4\u5bf6\uff08BMS\uff09\u7b49\u5168\u7403\u9818\u5148\u7684\u751f\u7269\u88fd\u85e5\u516c\u53f8\u64d4\u4efb\u904e\u591a\u500b\u904b\u71df\u3001\u92b7\u552e\u548c\u5e02\u5834\u71df\u92b7\u9818\u5c0e\u8077\u52d9\u3002 \u8fd1\u671f\u7ba1\u7dda\u4eae\u9ede \u81ea\u4e0a\u6b21\u8ca1\u5831\u767c\u4f48\u4ee5\u4f86\u518d\u9f0e\u91ab\u85e5\u4e3b\u8981\u7522\u54c1\u9032\u5c55\u5305\u62ec\uff1a \u816b\u7624\u9818\u57df\u7ba1\u7dda \u816b\u7624\u96fb\u5834\u6cbb\u7642\uff1a 2024\u5e743\u6708\uff0c\u518d\u9f0e\u91ab\u85e5\u5408\u4f5c\u5925\u4f34Novocure\u5ba3\u4f48\u91dd\u5c0d\u975e\u5c0f\u7d30\u80de\u80ba\u764c\uff08NSCLC\uff09\u8166\u8f49\u79fb\u76843\u671fMETIS\u81e8\u5e8a\u7814\u7a76\u53d6\u5f97\u967d\u6027\u7d50\u679c\u3002\u816b\u7624\u96fb\u5834\u6cbb\u7642\u806f\u5408\u652f\u6301\u7642\u6cd5\uff0c\u8207\u55ae\u7368\u63a5\u53d7\u652f\u6301\u7642\u6cd5\u76f8\u6bd4\uff0c\u4e2d\u4f4d\u81f3\u9871\u5167\u9032\u5c55\u6642\u9593\u986f\u8457\u6539\u5584\uff08\u5206\u5225\u70ba21.9\u500b\u6708\u548c11.3\u500b\u6708\uff09\u3002\u76f8\u95dc\u7d50\u679c\u5c07\u57286\u67083\u65e5\u5728\u829d\u52a0\u54e5\u8209\u884c\u76842024\u5e74\u7f8e\u570b\u81e8\u5e8a\u816b\u7624\u5b78\u6703\uff08ASCO\uff09\u5e74\u6703\u4e0a\u4f5c\u70ba\u5b8c\u6574\u53e3\u982d\u5831\u544a\uff08LBA\uff09\u767c\u4f48\u3002\u518d\u9f0e\u91ab\u85e5\u6b63\u5728\u5927\u4e2d\u83ef\u5340\u53c3\u52a0METIS\u7814\u7a76\u3002 Bemarituzumab (FGFR2b):\u00a0 \u518d\u9f0e\u91ab\u85e5\u6b63\u5728\u5927\u4e2d\u83ef\u5340\u62db\u52df\u60a3\u8005\u53c3\u52a0\u5168\u74033\u671f\u81e8\u5e8a\u7814\u7a76FORTITUDE-101\u548cFORTITUDE-102\uff1a FORTITUDE-101\u662f\u4e00\u9805bemarituzumab\u806f\u5408\u5316\u7642\u7528\u65bc\u80c3\u764c\u4e00\u7dda\u6cbb\u7642\u76843\u671f\u81e8\u5e8a\u7814\u7a76\u3002 FORTITUDE-102\u662f\u4e00\u9805bemarituzumab\u806f\u5408\u5316\u7642\u548c\u7d0d\u6b66\u5229\u5c24\u55ae\u6297\u7528\u65bc\u80c3\u764c\u4e00\u7dda\u6cbb\u7642\u76841b\/3\u671f\u81e8\u5e8a\u7814\u7a76\u3002 Tisotumab Vedotin\uff08\u7d44\u7e54\u56e0\u5b50 ADC\uff09 2024\u5e744\u6708\uff0c\u518d\u9f0e\u91ab\u85e5\u5408\u4f5c\u5925\u4f34\u8f1d\u745e\u548cGenmab A\/S\u5ba3\u4f48\uff0c\u7f8e\u570b\u98df\u54c1\u85e5\u54c1\u76e3\u7763\u7ba1\u7406\u5c40\uff08FDA\uff09\u5df2\u7d93\u6279\u51c6\u4e86tisotumab vedotin (TIVDAK\u00ae\uff09\u7684sBLA\uff0c\u5b8c\u5168\u6279\u51c6\u5176\u7528\u65bc\u6cbb\u7642\u5316\u7642\u671f\u9593\u6216\u5316\u7642\u5f8c\u75be\u75c5\u767c\u751f\u9032\u5c55\u7684\u5fa9\u767c\u6027\u6216\u8f49\u79fb\u6027\u5bae\u9838\u764c\u60a3\u8005\u3002\u00a0\u518d\u9f0e\u91ab\u85e5\u6b63\u5728\u5927\u4e2d\u83ef\u5340\u53c3\u8207\u5176\u5168\u74033\u671f\u81e8\u5e8ainnovaTV 301\u548c\u64f4\u5c55\u7814\u7a76\u3002 Adagrasib (KRASG12C): \u518d\u9f0e\u91ab\u85e5\u6b63\u5728\u8a55\u4f30\u5168\u74033\u671f\u81e8\u5e8a\u7814\u7a76KRYSTAL-12\u7684\u81e8\u5e8a\u6578\u64da\uff0c\u8a72\u7814\u7a76\u65e8\u5728\u8a55\u4f30adagrasib\u7528\u65bc\u5148\u524d\u7d93\u6cbb\u7684KRASG12C\u7a81\u8b8a\u975e\u5c0f\u7d30\u80de\u80ba\u764c\u60a3\u8005\uff0c\u540c\u6642\u6211\u5011\u5c07\u78ba\u5b9a\u8a72\u7522\u54c1\u4e0b\u4e00\u6b65\u7684\u9069\u61c9\u8b49\u958b\u767c\u3002 ZL-1310 (DLL3 ADC):\u00a0 2024\u5e743\u6708\uff0c\u518d\u9f0e\u91ab\u85e5\u5728\u6b50\u6d32\u80ba\u764c\u5927\u6703 (ELCC) \u4e0a\u516c\u4f48\u4e86ZL-1310\u81e8\u5e8a\u524d\u7814\u7a76\u7d50\u679c\uff0c\u5c55\u73fe\u4e86\u5176\u6cbb\u7642\u6f5b\u529b\u3002 \u518d\u9f0e\u91ab\u85e5\u6b63\u5728\u7f8e\u570b\u548c\u5927\u4e2d\u83ef\u5340\u70ba\u5176\u5168\u74031\u671f\u81e8\u5e8a\u7814\u7a76\u62db\u52df\u63a5\u53d7\u9251\u985e\u6cbb\u7642\u5f8c\u51fa\u73fe\u9032\u5c55\u7684\u5fa9\u767c\u548c\u96e3\u6cbb\u6027\u4e8c\u7dda\u53ca\u4ee5\u4e0a\u5c0f\u7d30\u80de\u80ba\u764c (SCLC) \u60a3\u8005\u3002 ZL-1218 (CCR8):\u00a0 \u518d\u9f0e\u91ab\u85e5\u6b63\u5728\u7f8e\u570b\u3001\u6b50\u6d32\u548c\u5927\u4e2d\u83ef\u5340\u70ba\u5176\u5168\u74031\u671f\u81e8\u5e8a\u7814\u7a76\u62db\u52df\u60a3\u8005\uff0c\u8a72\u7814\u7a76\u65e8\u5728\u8a55\u4f30ZL-1218\u55ae\u85e5\u4ee5\u53ca\u8207\u5e15\u535a\u5229\u73e0\u55ae\u6297\u806f\u5408\u6cbb\u7642\u665a\u671f\u60e1\u6027\u5be6\u9ad4\u7624\u3002 \u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u3001\u611f\u67d3\u6027\u75be\u75c5\u548c\u4e2d\u6a1e\u795e\u7d93\u7cfb\u7d71\u75be\u75c5\u9818\u57df\u7ba1\u7dda \u827e\u52a0\u83ab\u5fb7\uff08FcRn\uff09\uff1a 2024\u5e744\u6708\uff0c\u518d\u9f0e\u91ab\u85e5\u5411\u4e2d\u570b\u570b\u5bb6\u85e5\u54c1\u76e3\u7763\u7ba1\u7406\u5c40\uff08NMPA\uff09\u63d0\u4ea4\u4e86\u827e\u52a0\u83ab\u5fb7\u76ae\u4e0b\u6ce8\u5c04\u5291\u578b\u7528\u65bc\u6162\u6027\u708e\u6027\u812b\u9ad3\u9798\u6027\u591a\u767c\u6027\u795e\u7d93\u6839\u795e\u7d93\u75c5\uff08CIDP\uff09\u7684sBLA\u3002 Xanomeline-Trospium\uff08KarXT\uff09\uff08M1\/M4\u578b\u6bd2\u8548\u9e7c\u4e59\u9170\u81bd\u9e7c\u53d7\u9ad4\u6fc0\u52d5\u5291\uff09: 2024\u5e744\u6708\uff0c\u518d\u9f0e\u91ab\u85e5\u5408\u4f5c\u5925\u4f34BMS\u5728\u570b\u969b\u7cbe\u795e\u5206\u88c2\u75c7\u7814\u7a76\u5b78\u6703 (SIRS) 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\u518d\u9f0e\u91ab\u85e5\u6b63\u5728\u4e2d\u570b\u5167\u5730\u62db\u52df\u60a3\u8005\u53c3\u52a0\u8a3b\u518a\u6027\u6a4b\u63a5\u7814\u7a76\u3002 2024\u5e74\u7684\u9810\u671f\u91cd\u8981\u91cc\u7a0b\u7891\u4e8b\u4ef6 \u816b\u7624\u9818\u57df \u745e\u666e\u66ff\u5c3c \u745e\u666e\u66ff\u5c3c\u7528\u65bc\u6cbb\u7642ROS1\u967d\u6027\u5c40\u90e8\u665a\u671f\u6216\u8f49\u79fb\u6027NSCLC\u6210\u4eba\u60a3\u8005\u7684NDA\u6709\u671b\u7372NMPA\u6279\u51c6\u3002 \u816b\u7624\u96fb\u5834\u6cbb\u7642 \u518d\u9f0e\u91ab\u85e5\u5c07\u5411NMPA\u63d0\u4ea4\u816b\u7624\u96fb\u5834\u6cbb\u7642\u7528\u65bc\u9251\u985e\u6cbb\u7642\u5f8c\u51fa\u73fe\u75be\u75c5\u9032\u5c55\u7684\u4e8c\u7dda\u53ca\u4ee5\u4e0aNSCLC \u7684\u4e0a\u5e02\u8a31\u53ef\u7533\u8acb\uff08MAA\uff09\u3002 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\u64ce\u6a02\u00ae\uff1a2024\u5e74\u7b2c\u4e00\u5b63\u5ea6\u92b7\u552e\u6536\u5165\u70ba610\u842c\u7f8e\u5143\uff0c2023\u5e74\u540c\u671f\u70ba130\u842c\u7f8e\u5143\uff0c\u540c\u6bd4\u589e\u9577367%\uff0c\u4e3b\u8981\u662f\u7531\u65bc\u5176\u65bc2023\u5e74\u7b2c\u4e00\u5b63\u5ea6\u88ab\u7d0d\u5165NRDL\uff0c\u7528\u65bc\u665a\u671f\u56db\u7dda\u80c3\u8178\u9593\u8cea\u7624\uff08GIST\uff09\u7684\u6cbb\u7642\u3002 \u7d10\u518d\u6a02\u00ae\uff1a2024\u5e74\u7b2c\u4e00\u5b63\u5ea6\u92b7\u552e\u6536\u5165\u70ba990\u842c\u7f8e\u5143\uff0c2023\u5e74\u540c\u671f\u70ba550\u842c\u7f8e\u5143\uff0c\u540c\u6bd4\u589e\u957781%\uff0c\u4e3b\u8981\u662f\u7531\u65bc\u7d10\u518d\u6a02\u975c\u8108\u6ce8\u5c04\u5291\u578b\u65bc2023\u5e74\u7b2c\u4e00\u5b63\u5ea6\u88ab\u7d0d\u5165NRDL\uff0c\u7528\u65bc\u6cbb\u7642\u6210\u4eba\u793e\u5340\u7372\u5f97\u6027\u7d30\u83cc\u6027\u80ba\u708e (CABP) \u548c\u6025\u6027\u7d30\u83cc\u6027\u76ae\u819a\u548c\u76ae\u819a\u7d50\u69cb\u611f\u67d3 (ABSSSI)\uff0c2024\u5e74\u7b2c\u4e00\u5b63\u5ea6\u4e0a\u8ff0\u9069\u61c9\u8b49\u7684\u53e3\u670d\u5291\u578b\u88ab\u7d0d\u5165NRDL\u3002 2024\u5e74\u7b2c\u4e00\u5b63\u5ea6\u7684\u7814\u767c\u958b\u652f\u70ba5,460\u842c\u7f8e\u5143\uff0c2023\u5e74\u540c\u671f\u70ba4,850\u842c\u7f8e\u5143\u3002\u9019\u4e00\u589e\u9577\u4e3b\u8981\u662f\u7531\u65bc\u65b0\u555f\u52d5\u548c\u6b63\u5728\u958b\u5c55\u7684\u81e8\u5e8a\u7814\u7a76\u7684\u8cbb\u7528\u7684\u589e\u52a0\uff0c\u90e8\u5206\u88ab\u8a31\u53ef\u7522\u54c1\u7684\u91cc\u7a0b\u7891\u6b3e\u9805\u7684\u6e1b\u5c11\u6240\u62b5\u92b7\u3002 2024\u5e74\u7b2c\u4e00\u5b63\u5ea6\u7684\u92b7\u552e\u3001\u4e00\u822c\u548c\u884c\u653f\u958b\u652f\u70ba6,920\u842c\u7f8e\u5143\uff0c2023\u5e74\u540c\u671f\u70ba6,250\u842c\u7f8e\u5143\u3002\u9019\u4e00\u589e\u9577\u4e3b\u8981\u662f\u7531\u65bc\u8207\u885b\u5049\u8fe6\u4e0a\u5e02\u6709\u95dc\u7684\u4e00\u822c\u92b7\u552e\u8cbb\u7528\u7684\u589e\u9577\u548c\u4eba\u54e1\u7684\u589e\u52a0\u3002 2024\u5e74\u7b2c\u4e00\u5b63\u5ea6\u8667\u640d\u6de8\u984d\u70ba5,350\u842c\u7f8e\u5143\uff0c\u6bcf\u80a1\u666e\u901a\u80a1\u8667\u640d0.05\u7f8e\u5143\uff08\u6bcf\u4efd\u7f8e\u570b\u5b58\u6258\u80a1\u4efd\uff08ADS\uff09\u8667\u640d\u70ba0.55\u7f8e\u5143\uff09\uff0c2023\u5e74\u540c\u671f\u8667\u640d\u6de8\u984d\u70ba4,910\u842c\u7f8e\u5143\u3002\u6bcf\u80a1\u666e\u901a\u80a1\u8667\u640d0.05\u7f8e\u5143\uff08\u6bcf\u4efdADS\u8667\u640d\u70ba0.51\u7f8e\u5143\uff09\u3002 \u622a\u81f32024\u5e743\u670831\u65e5\uff0c\u73fe\u91d1\u53ca\u73fe\u91d1\u7b49\u50f9\u7269\u3001\u77ed\u671f\u6295\u8cc7\u3001\u6d41\u52d5\u53d7\u9650\u5236\u73fe\u91d1\u7e3d\u8a08\u70ba7.508\u5104\u7f8e\u5143\uff0c\u622a\u81f32023\u5e7412\u670831\u65e5\u70ba8.065\u5104\u7f8e\u5143\u3002 \u516c\u53f8\u9032\u5c55 2024\u5e744\u6708\uff0c\u6731\u5f64\u5148\u751f\u52a0\u5165\u518d\u9f0e\u91ab\u85e5\uff0c\u64d4\u4efb\u5927\u4e2d\u83ef\u53402\u9996\u5e2d\u5546\u52d9\u5b98\u3002\u6731\u5f64\u5148\u751f\u5728\u69cb\u5efa\u5275\u65b0\u5546\u696d\u6a21\u5f0f\u548c\u8cc7\u6e90\u6574\u5408\u65b9\u9762\u64c1\u6709\u8c50\u5bcc\u7684\u7d93\u9a57\uff0c\u5c07\u5e6b\u52a9\u6211\u5011\u9032\u4e00\u6b65\u52a0\u5f37\u5546\u696d\u5316\u904b\u71df\uff0c\u63a8\u52d5\u5927\u4e2d\u83ef\u5340\u7684\u92b7\u552e\u548c\u5229\u6f64\u589e\u9577\u3002\u5728\u52a0\u5165\u518d\u9f0e\u91ab\u85e5\u4e4b\u524d\uff0c\u4ed6\u5728\u5148\u8072\u518d\u660e\u4efb\u8077\uff0c\u6700\u8fd1\u7684\u8077\u4f4d\u70ba\u9996\u5e2d\u904b\u71df\u5b98\uff0c\u8ca0\u8cac\u71df\u92b7\u548c\u88fd\u85e5\u696d\u52d9\u3002\u5728\u6b64\u4e4b\u524d\uff0c\u4ed6\u66fe\u5728\u963f\u65af\u5229\u5eb7\u3001\u7f85\u6c0f\u3001\u8cfd\u8afe\u83f2\u548c\u767e\u6642\u7f8e\u65bd\u8cb4\u5bf6\uff08BMS\uff09\u7b49\u5168\u7403\u9818\u5148\u7684\u751f\u7269\u88fd\u85e5\u516c\u53f8\u64d4\u4efb\u904e\u591a\u500b\u904b\u71df\u3001\u92b7\u552e\u548c\u5e02\u5834\u71df\u92b7\u9818\u5c0e\u8077\u52d9\u3002 \u8fd1\u671f\u7ba1\u7dda\u4eae\u9ede \u81ea\u4e0a\u6b21\u8ca1\u5831\u767c\u4f48\u4ee5\u4f86\u518d\u9f0e\u91ab\u85e5\u4e3b\u8981\u7522\u54c1\u9032\u5c55\u5305\u62ec\uff1a \u816b\u7624\u9818\u57df\u7ba1\u7dda \u816b\u7624\u96fb\u5834\u6cbb\u7642\uff1a 2024\u5e743\u6708\uff0c\u518d\u9f0e\u91ab\u85e5\u5408\u4f5c\u5925\u4f34Novocure\u5ba3\u4f48\u91dd\u5c0d\u975e\u5c0f\u7d30\u80de\u80ba\u764c\uff08NSCLC\uff09\u8166\u8f49\u79fb\u76843\u671fMETIS\u81e8\u5e8a\u7814\u7a76\u53d6\u5f97\u967d\u6027\u7d50\u679c\u3002\u816b\u7624\u96fb\u5834\u6cbb\u7642\u806f\u5408\u652f\u6301\u7642\u6cd5\uff0c\u8207\u55ae\u7368\u63a5\u53d7\u652f\u6301\u7642\u6cd5\u76f8\u6bd4\uff0c\u4e2d\u4f4d\u81f3\u9871\u5167\u9032\u5c55\u6642\u9593\u986f\u8457\u6539\u5584\uff08\u5206\u5225\u70ba21.9\u500b\u6708\u548c11.3\u500b\u6708\uff09\u3002\u76f8\u95dc\u7d50\u679c\u5c07\u57286\u67083\u65e5\u5728\u829d\u52a0\u54e5\u8209\u884c\u76842024\u5e74\u7f8e\u570b\u81e8\u5e8a\u816b\u7624\u5b78\u6703\uff08ASCO\uff09\u5e74\u6703\u4e0a\u4f5c\u70ba\u5b8c\u6574\u53e3\u982d\u5831\u544a\uff08LBA\uff09\u767c\u4f48\u3002\u518d\u9f0e\u91ab\u85e5\u6b63\u5728\u5927\u4e2d\u83ef\u5340\u53c3\u52a0METIS\u7814\u7a76\u3002 Bemarituzumab (FGFR2b):\u00a0 \u518d\u9f0e\u91ab\u85e5\u6b63\u5728\u5927\u4e2d\u83ef\u5340\u62db\u52df\u60a3\u8005\u53c3\u52a0\u5168\u74033\u671f\u81e8\u5e8a\u7814\u7a76FORTITUDE-101\u548cFORTITUDE-102\uff1a FORTITUDE-101\u662f\u4e00\u9805bemarituzumab\u806f\u5408\u5316\u7642\u7528\u65bc\u80c3\u764c\u4e00\u7dda\u6cbb\u7642\u76843\u671f\u81e8\u5e8a\u7814\u7a76\u3002 FORTITUDE-102\u662f\u4e00\u9805bemarituzumab\u806f\u5408\u5316\u7642\u548c\u7d0d\u6b66\u5229\u5c24\u55ae\u6297\u7528\u65bc\u80c3\u764c\u4e00\u7dda\u6cbb\u7642\u76841b\/3\u671f\u81e8\u5e8a\u7814\u7a76\u3002 Tisotumab Vedotin\uff08\u7d44\u7e54\u56e0\u5b50 ADC\uff09 2024\u5e744\u6708\uff0c\u518d\u9f0e\u91ab\u85e5\u5408\u4f5c\u5925\u4f34\u8f1d\u745e\u548cGenmab A\/S\u5ba3\u4f48\uff0c\u7f8e\u570b\u98df\u54c1\u85e5\u54c1\u76e3\u7763\u7ba1\u7406\u5c40\uff08FDA\uff09\u5df2\u7d93\u6279\u51c6\u4e86tisotumab vedotin (TIVDAK\u00ae\uff09\u7684sBLA\uff0c\u5b8c\u5168\u6279\u51c6\u5176\u7528\u65bc\u6cbb\u7642\u5316\u7642\u671f\u9593\u6216\u5316\u7642\u5f8c\u75be\u75c5\u767c\u751f\u9032\u5c55\u7684\u5fa9\u767c\u6027\u6216\u8f49\u79fb\u6027\u5bae\u9838\u764c\u60a3\u8005\u3002\u00a0\u518d\u9f0e\u91ab\u85e5\u6b63\u5728\u5927\u4e2d\u83ef\u5340\u53c3\u8207\u5176\u5168\u74033\u671f\u81e8\u5e8ainnovaTV 301\u548c\u64f4\u5c55\u7814\u7a76\u3002 Adagrasib (KRASG12C): \u518d\u9f0e\u91ab\u85e5\u6b63\u5728\u8a55\u4f30\u5168\u74033\u671f\u81e8\u5e8a\u7814\u7a76KRYSTAL-12\u7684\u81e8\u5e8a\u6578\u64da\uff0c\u8a72\u7814\u7a76\u65e8\u5728\u8a55\u4f30adagrasib\u7528\u65bc\u5148\u524d\u7d93\u6cbb\u7684KRASG12C\u7a81\u8b8a\u975e\u5c0f\u7d30\u80de\u80ba\u764c\u60a3\u8005\uff0c\u540c\u6642\u6211\u5011\u5c07\u78ba\u5b9a\u8a72\u7522\u54c1\u4e0b\u4e00\u6b65\u7684\u9069\u61c9\u8b49\u958b\u767c\u3002 ZL-1310 (DLL3 ADC):\u00a0 2024\u5e743\u6708\uff0c\u518d\u9f0e\u91ab\u85e5\u5728\u6b50\u6d32\u80ba\u764c\u5927\u6703 (ELCC) \u4e0a\u516c\u4f48\u4e86ZL-1310\u81e8\u5e8a\u524d\u7814\u7a76\u7d50\u679c\uff0c\u5c55\u73fe\u4e86\u5176\u6cbb\u7642\u6f5b\u529b\u3002 \u518d\u9f0e\u91ab\u85e5\u6b63\u5728\u7f8e\u570b\u548c\u5927\u4e2d\u83ef\u5340\u70ba\u5176\u5168\u74031\u671f\u81e8\u5e8a\u7814\u7a76\u62db\u52df\u63a5\u53d7\u9251\u985e\u6cbb\u7642\u5f8c\u51fa\u73fe\u9032\u5c55\u7684\u5fa9\u767c\u548c\u96e3\u6cbb\u6027\u4e8c\u7dda\u53ca\u4ee5\u4e0a\u5c0f\u7d30\u80de\u80ba\u764c (SCLC) \u60a3\u8005\u3002 ZL-1218 (CCR8):\u00a0 \u518d\u9f0e\u91ab\u85e5\u6b63\u5728\u7f8e\u570b\u3001\u6b50\u6d32\u548c\u5927\u4e2d\u83ef\u5340\u70ba\u5176\u5168\u74031\u671f\u81e8\u5e8a\u7814\u7a76\u62db\u52df\u60a3\u8005\uff0c\u8a72\u7814\u7a76\u65e8\u5728\u8a55\u4f30ZL-1218\u55ae\u85e5\u4ee5\u53ca\u8207\u5e15\u535a\u5229\u73e0\u55ae\u6297\u806f\u5408\u6cbb\u7642\u665a\u671f\u60e1\u6027\u5be6\u9ad4\u7624\u3002 \u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u3001\u611f\u67d3\u6027\u75be\u75c5\u548c\u4e2d\u6a1e\u795e\u7d93\u7cfb\u7d71\u75be\u75c5\u9818\u57df\u7ba1\u7dda \u827e\u52a0\u83ab\u5fb7\uff08FcRn\uff09\uff1a 2024\u5e744\u6708\uff0c\u518d\u9f0e\u91ab\u85e5\u5411\u4e2d\u570b\u570b\u5bb6\u85e5\u54c1\u76e3\u7763\u7ba1\u7406\u5c40\uff08NMPA\uff09\u63d0\u4ea4\u4e86\u827e\u52a0\u83ab\u5fb7\u76ae\u4e0b\u6ce8\u5c04\u5291\u578b\u7528\u65bc\u6162\u6027\u708e\u6027\u812b\u9ad3\u9798\u6027\u591a\u767c\u6027\u795e\u7d93\u6839\u795e\u7d93\u75c5\uff08CIDP\uff09\u7684sBLA\u3002 Xanomeline-Trospium\uff08KarXT\uff09\uff08M1\/M4\u578b\u6bd2\u8548\u9e7c\u4e59\u9170\u81bd\u9e7c\u53d7\u9ad4\u6fc0\u52d5\u5291\uff09: 2024\u5e744\u6708\uff0c\u518d\u9f0e\u91ab\u85e5\u5408\u4f5c\u5925\u4f34BMS\u5728\u570b\u969b\u7cbe\u795e\u5206\u88c2\u75c7\u7814\u7a76\u5b78\u6703 (SIRS) 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