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1 \u91ab\u9662\u7ba1\u7406\u5c40\u9999\u6e2f\u764c\u75c7\u8cc7\u6599\u7d71\u8a08\u4e2d\u5fc32021
2 Chan YHY et al. Hong Kong Med J. 2023;29(3):198-207. (\u53ea\u9650\u82f1\u6587\u7248\u672c)
3 Kong X et al. Eur J Cancer. 2011;47(14):2084-2090. (\u53ea\u9650\u82f1\u6587\u7248\u672c)
4\u00a0Schmid P et al. N Eng J Med 2020;382:810-21. (\u53ea\u9650\u82f1\u6587\u7248\u672c)<\/p>\n
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complete response\uff09\u2014 \u5373\u60a3\u8005\u5b8c\u6210\u8853\u524d\u6cbb\u7642\u5f8c\u816b\u7624\u5b8c\u5168\u6d88\u5931\uff0c\u800c\u4e14\u5728\u624b\u8853\u5f8c\u7684\u75c5\u7406\u6aa2\u67e5\u7576\u4e2d\u4ea6\u627e\u4e0d\u5230\u764c\u7d30\u80de\u3002\u6b64\u985e\u60a3\u8005\u7684\u9810\u5f8c\u4ea6\u6703\u76f8\u5c0d\u8f03\u597d\u30023 \u5c08\u5bb6\u5c0f\u7d44\u7d93\u8a0e\u8ad6\u53ca\u6295\u7968\u5f8c\u9054\u6210\u6cbb\u7642\u5171\u8b58\u3002\u5728\u8a3a\u65b7\u65b9\u9762\uff0c\u5c08\u5bb6\u5c0f\u7d44\u540c\u610f\u70ba\u4e73\u764c\u500b\u6848\u61c9\u9032\u884c\u514d\u75ab\u7d44\u7e54\u5316\u5b78\u67d3\u8272\u00a0\uff08Immunohistochemistry \u2013 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survival\uff09\u4ea6\u6bd4\u55ae\u7528\u5316\u7642\u7684\u60a3\u8005\u986f\u8457\u5ef6\u9577\u30024\u300c\u75c5\u4eba\u539f\u672c\u53ef\u80fd\u9700\u8981\u63a5\u53d7\u5168\u4e73\u5207\u9664\u624b\u8853\uff0c\u4f46\u82e5\u5148\u63a5\u53d7\u514d\u75ab\u6cbb\u7642\u518d\u914d\u5408\u5316\u7642\u4f5c\u70ba\u8853\u524d\u6cbb\u7642\uff0c\u6709\u6a5f\u6703\u7e2e\u5c0f\u816b\u7624\uff0c\u4ee4\u75c5\u4eba\u6bcb\u9808\u5207\u9664\u6574\u500b\u4e73\u623f\uff0c\u5c0d\u75c5\u4eba\u7684\u5fc3\u7406\u548c\u751f\u6d3b\u8cea\u7d20\u90fd\u6709\u5f88\u5927\u7684\u6539\u5584\u3002\u300d 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\u6bcf\u6b21\u7642\u7a0b\u4f7f\u7528\u5339\u535a\u5229\u7d44\u55ae\u6297\uff08Pembrolizumab\uff09200 \u6beb\u514b\u6216\u00a0400 \u6beb\u514b\u5291\u91cf\u7684\u75c5\u4eba\u3002 *\u79c1\u5bb6\u91ab\u9662\u6216\u8a3a\u6240\u8f49\u4ecb\u7684\u60a3\u8005\u9700\u901a\u904e\u5165\u606f\u5be9\u67e5\uff0c\u6700\u8fd112\u500b\u6708\u5e73\u5747\u500b\u4eba\u5165\u606f\u6bcf\u6708\u5c11\u65bc\u6e2f\u5e636\u842c\u5143 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Hong Kong Med J. 2023;29(3):198-207. (\u53ea\u9650\u82f1\u6587\u7248\u672c)3 Kong X et al. Eur J Cancer. 2011;47(14):2084-2090. (\u53ea\u9650\u82f1\u6587\u7248\u672c)4\u00a0Schmid P et al. N Eng J Med 2020;382:810-21. (\u53ea\u9650\u82f1\u6587\u7248\u672c) \u00a0<\/p>\n","protected":false},"author":0,"featured_media":0,"comment_status":"","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_generate-full-width-content":"","spay_email":"","footnotes":""},"categories":[1],"tags":[],"yoast_head":"\n
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complete response\uff09\u2014 \u5373\u60a3\u8005\u5b8c\u6210\u8853\u524d\u6cbb\u7642\u5f8c\u816b\u7624\u5b8c\u5168\u6d88\u5931\uff0c\u800c\u4e14\u5728\u624b\u8853\u5f8c\u7684\u75c5\u7406\u6aa2\u67e5\u7576\u4e2d\u4ea6\u627e\u4e0d\u5230\u764c\u7d30\u80de\u3002\u6b64\u985e\u60a3\u8005\u7684\u9810\u5f8c\u4ea6\u6703\u76f8\u5c0d\u8f03\u597d\u30023 \u5c08\u5bb6\u5c0f\u7d44\u7d93\u8a0e\u8ad6\u53ca\u6295\u7968\u5f8c\u9054\u6210\u6cbb\u7642\u5171\u8b58\u3002\u5728\u8a3a\u65b7\u65b9\u9762\uff0c\u5c08\u5bb6\u5c0f\u7d44\u540c\u610f\u70ba\u4e73\u764c\u500b\u6848\u61c9\u9032\u884c\u514d\u75ab\u7d44\u7e54\u5316\u5b78\u67d3\u8272\u00a0\uff08Immunohistochemistry \u2013 IHC\uff09\u6aa2\u6e2c\uff0c\u78ba\u5b9a\u75c5\u4eba\u7684ER\u3001PR\u548cHER2\u72c0\u6cc1\uff0c\u70ba\u60a3\u8005\u7684\u4e73\u764c\u5206\u985e\uff0c\u4ee5\u5236\u5b9a\u91dd\u5c0d\u6027\u7684\u6cbb\u7642\u65b9\u6848\u3002\u5728\u6cbb\u7642\u65b9\u9762\uff0c\u5c0d\u7b2cII\u671f\u548c\u7b2cIII\u671f\u4e09\u9670\u6027\u4e73\u764c\u60a3\u8005\uff0c\u53ea\u8981\u81e8\u5e8a\u72c0\u6cc1\u5408\u9069\uff0c\u8853\u524d\u6cbb\u7642\u61c9\u8a72\u88ab\u8996\u70ba\u6a19\u6e96\u548c\u512a\u5148\u8003\u616e\u7684\u6cbb\u7642\u65b9\u6848\u3002\u91ab\u751f\u4ea6\u61c9\u8a72\u8003\u616e\u4ee5\u514d\u75ab\u6cbb\u7642\u914d\u5408\u5316\u7642\u4f5c\u70ba\u8853\u524d\u6cbb\u7642\u548c\u8853\u5f8c\u8f14\u52a9\u6cbb\u7642\u3002 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\u6bcf\u6b21\u7642\u7a0b\u4f7f\u7528\u5339\u535a\u5229\u7d44\u55ae\u6297\uff08Pembrolizumab\uff09200 \u6beb\u514b\u6216\u00a0400 \u6beb\u514b\u5291\u91cf\u7684\u75c5\u4eba\u3002 *\u79c1\u5bb6\u91ab\u9662\u6216\u8a3a\u6240\u8f49\u4ecb\u7684\u60a3\u8005\u9700\u901a\u904e\u5165\u606f\u5be9\u67e5\uff0c\u6700\u8fd112\u500b\u6708\u5e73\u5747\u500b\u4eba\u5165\u606f\u6bcf\u6708\u5c11\u65bc\u6e2f\u5e636\u842c\u5143 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complete response\uff09\u2014 \u5373\u60a3\u8005\u5b8c\u6210\u8853\u524d\u6cbb\u7642\u5f8c\u816b\u7624\u5b8c\u5168\u6d88\u5931\uff0c\u800c\u4e14\u5728\u624b\u8853\u5f8c\u7684\u75c5\u7406\u6aa2\u67e5\u7576\u4e2d\u4ea6\u627e\u4e0d\u5230\u764c\u7d30\u80de\u3002\u6b64\u985e\u60a3\u8005\u7684\u9810\u5f8c\u4ea6\u6703\u76f8\u5c0d\u8f03\u597d\u30023 \u5c08\u5bb6\u5c0f\u7d44\u7d93\u8a0e\u8ad6\u53ca\u6295\u7968\u5f8c\u9054\u6210\u6cbb\u7642\u5171\u8b58\u3002\u5728\u8a3a\u65b7\u65b9\u9762\uff0c\u5c08\u5bb6\u5c0f\u7d44\u540c\u610f\u70ba\u4e73\u764c\u500b\u6848\u61c9\u9032\u884c\u514d\u75ab\u7d44\u7e54\u5316\u5b78\u67d3\u8272\u00a0\uff08Immunohistochemistry \u2013 IHC\uff09\u6aa2\u6e2c\uff0c\u78ba\u5b9a\u75c5\u4eba\u7684ER\u3001PR\u548cHER2\u72c0\u6cc1\uff0c\u70ba\u60a3\u8005\u7684\u4e73\u764c\u5206\u985e\uff0c\u4ee5\u5236\u5b9a\u91dd\u5c0d\u6027\u7684\u6cbb\u7642\u65b9\u6848\u3002\u5728\u6cbb\u7642\u65b9\u9762\uff0c\u5c0d\u7b2cII\u671f\u548c\u7b2cIII\u671f\u4e09\u9670\u6027\u4e73\u764c\u60a3\u8005\uff0c\u53ea\u8981\u81e8\u5e8a\u72c0\u6cc1\u5408\u9069\uff0c\u8853\u524d\u6cbb\u7642\u61c9\u8a72\u88ab\u8996\u70ba\u6a19\u6e96\u548c\u512a\u5148\u8003\u616e\u7684\u6cbb\u7642\u65b9\u6848\u3002\u91ab\u751f\u4ea6\u61c9\u8a72\u8003\u616e\u4ee5\u514d\u75ab\u6cbb\u7642\u914d\u5408\u5316\u7642\u4f5c\u70ba\u8853\u524d\u6cbb\u7642\u548c\u8853\u5f8c\u8f14\u52a9\u6cbb\u7642\u3002 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survival\uff09\u4ea6\u6bd4\u55ae\u7528\u5316\u7642\u7684\u60a3\u8005\u986f\u8457\u5ef6\u9577\u30024\u300c\u75c5\u4eba\u539f\u672c\u53ef\u80fd\u9700\u8981\u63a5\u53d7\u5168\u4e73\u5207\u9664\u624b\u8853\uff0c\u4f46\u82e5\u5148\u63a5\u53d7\u514d\u75ab\u6cbb\u7642\u518d\u914d\u5408\u5316\u7642\u4f5c\u70ba\u8853\u524d\u6cbb\u7642\uff0c\u6709\u6a5f\u6703\u7e2e\u5c0f\u816b\u7624\uff0c\u4ee4\u75c5\u4eba\u6bcb\u9808\u5207\u9664\u6574\u500b\u4e73\u623f\uff0c\u5c0d\u75c5\u4eba\u7684\u5fc3\u7406\u548c\u751f\u6d3b\u8cea\u7d20\u90fd\u6709\u5f88\u5927\u7684\u6539\u5584\u3002\u300d 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